Template:Infobox drug/doc

{{anchor|1=Single chemical}}

Drugs that are a simple chemical compound (about 90% of the drug articles are). Short parameter list:

{{Infobox drug

| drug_name =

| INN =

| type =

| image =

| image_class =

| alt =

| caption =

| pronounce =

| tradename =

| Drugs.com =

| MedlinePlus =

| pregnancy_AU =

| pregnancy_AU_comment =

| pregnancy_category=

| routes_of_administration =

| ATCvet =

| ATC_prefix =

| ATC_suffix =

| legal_AU =

| legal_AU_comment =

| legal_BR =

| legal_BR_comment =

| legal_CA =

| legal_CA_comment =

| legal_DE =

| legal_DE_comment =

| legal_NZ =

| legal_NZ_comment =

| legal_UK =

| legal_UK_comment =

| legal_US =

| legal_US_comment =

| legal_EU =

| legal_EU_comment =

| legal_UN =

| legal_UN_comment =

| legal_status =

| bioavailability =

| protein_bound =

| metabolism =

| metabolites =

| onset =

| elimination_half-life =

| duration_of_action=

| excretion =

| CAS_number =

| PubChem =

| DrugBank =

| IUPAC_name =

| chemical_formula =

| molecular_weight =

}}

Full single-drug template with extended fields:

{{Infobox drug

| drug_name =

| INN =

| type =

| image =

| image_class =

| width =

| alt =

| caption =

| image2 =

| image_class2 =

| width2 =

| alt2 =

| caption2 =

| imageL =

| image_classL =

| widthL =

| altL =

| imageR =

| image_classR =

| widthR =

| altR =

| captionLR =

| pronounce =

| tradename =

| Drugs.com =

| MedlinePlus =

| licence_CA =

| licence_EU =

| DailyMedID =

| licence_US =

| pregnancy_AU =

| pregnancy_AU_comment =

| pregnancy_category=

| tolerance_potential =

| dependency_liability =

| addiction_liability =

| routes_of_administration =

| class =

| ATCvet =

| ATC_prefix =

| ATC_suffix =

| ATC_supplemental =

| legal_AU =

| legal_AU_comment =

| legal_BR =

| legal_BR_comment =

| legal_CA =

| legal_CA_comment =

| legal_DE =

| legal_DE_comment =

| legal_NZ =

| legal_NZ_comment =

| legal_UK =

| legal_UK_comment =

| legal_US =

| legal_US_comment =

| legal_EU =

| legal_EU_comment =

| legal_UN =

| legal_UN_comment =

| legal_status =

| bioavailability =

| protein_bound =

| metabolism =

| metabolites =

| onset =

| elimination_half-life =

| duration_of_action=

| excretion =

| CAS_number =

| CAS_supplemental =

| PubChem =

| PubChemSubstance =

| IUPHAR_ligand =

| DrugBank =

| ChemSpiderID =

| UNII =

| KEGG =

| ChEBI =

| ChEMBL =

| NIAID_ChemDB =

| PDB_ligand =

| synonyms =

| IUPAC_name =

| chemical_formula =

| C= | H= | Ag= | Al= | As= | Au= | B= | Bi= | Br= | Ca= | Cl= | Co= | F= | Fe= | Gd= | I=

| K= | Li= | Mg= | Mn= | N= | Na= | O= | P= | Pt= | S= | Sb= | Se= | Sr= | Tc= | Zn= | charge=

| molecular_weight =

| SMILES =

| Jmol =

| StdInChI =

| StdInChI_comment =

| StdInChIKey =

| density =

| density_notes =

| melting_point =

| melting_high =

| melting_notes =

| boiling_point =

| boiling_notes =

| solubility =

| sol_units =

| specific_rotation =

}}

The {{Webarchive|url=https://web.archive.org/web/20230602170004/https://alyw234237.github.io/wiki-drugbox-chembox-maker/|title=Wikipedia Drugbox and Chembox Maker|date=mdy}} can be used to automatically generate single-chemical drugbox templates. Note: For unknown reason the For quicker access, this tool can be added to the tools section of Wikipedia's left sidebar via User:Qwerfjkl/scripts/chemboxmaker.

Another option is Diberri and Boghog's excellent [https://tools.wmflabs.org/citation-template-filling/cgi-bin/index.cgi Wikipedia template filling tool] which will generate a populated template to copy and paste into an article if "DrugBank ID" is selected in the dropdown menu and a DrugBank ID number (which may be obtained from [http://redpoll.pharmacy.ualberta.ca/drugbank/ DrugBank search]) is added in the adjacent field. Please select for Fill template vertically, but as Wikipedia is a general encyclopedia, most drugs do not warrant Show extended fields. However, drugbox generation with this tool [https://citation-template-filling.toolforge.org/cgi-bin/index.cgi?type=drugbank_id&id=DB00328 is currently broken] and [https://web.archive.org/web/20200712040837/https://citation-template-filling.toolforge.org/cgi-bin/index.cgi?type=drugbank_id&id=DB00328 has been for some time].

{{anchor|1=Combination of drugs}}

For drug-combinations, at least two components must be defined, with more optional (up to 6). For each component:

| componentn =

| classn =

Example for Seretide:

{{Infobox drug

| drug_name = Seretide

| type = combo

| component1 = Fluticasone

| class1 = Glucocorticoid

| component2 = Salmeterol

| class2 = Long-acting beta2 agonist

}}

| drug_name = Seretide

| type = combo

| component1 = Fluticasone

| class1 = Glucocorticoid

| component2 = Salmeterol

| class2 = Long-acting beta2 agonist

Generally combination articles will not need to display the molecular images of its constituents (the relevant specific articles would have the images). It disables all Chemical & Pharmacology parameters (which describe properties of single drug items). These redundant disabled parameters are best not included in the template calling, so use the following abridged forms of the template:

Shortened combination product form:

{{Infobox drug

| drug_name =

| type = combo

| component1 =

| class1 =

| component2 =

| class2 =

| pronounce =

| tradename =

| Drugs.com =

| MedlinePlus =

| pregnancy_AU =

| pregnancy_AU_comment =

| pregnancy_category=

| routes_of_administration =

| ATCvet =

| ATC_prefix =

| ATC_suffix =

| legal_AU =

| legal_AU_comment =

| legal_BR =

| legal_BR_comment =

| legal_CA =

| legal_CA_comment =

| legal_DE =

| legal_DE_comment =

| legal_NZ =

| legal_NZ_comment =

| legal_UK =

| legal_UK_comment =

| legal_US =

| legal_US_comment =

| legal_EU =

| legal_EU_comment =

| legal_UN =

| legal_UN_comment =

| legal_status =

| CAS_number =

| PubChem =

| DrugBank =

| KEGG =

}}

Full combination product template with extended fields and allowing for up to six items:

{{Infobox drug

| drug_name =

| type = combo

| component1 =

| class1 =

| component2 =

| class2 =

| component3 =

| class3 =

| component4 =

| class4 =

| component5 =

| class5 =

| component6 =

| class6 =

| pronounce =

| tradename =

| Drugs.com =

| MedlinePlus =

| licence_CA =

| licence_EU =

| DailyMedID =

| licence_US =

| pregnancy_AU =

| pregnancy_AU_comment =

| pregnancy_category=

| dependency_liability =

| addiction_liability =

| routes_of_administration =

| ATCvet =

| ATC_prefix =

| ATC_suffix =

| ATC_supplemental =

| legal_AU =

| legal_AU_comment =

| legal_BR =

| legal_BR_comment =

| legal_CA =

| legal_CA_comment =

| legal_DE =

| legal_DE_comment =

| legal_NZ =

| legal_NZ_comment =

| legal_UK =

| legal_UK_comment =

| legal_US =

| legal_US_comment =

| legal_EU =

| legal_EU_comment =

| legal_UN =

| legal_UN_comment =

| legal_status =

| CAS_number =

| CAS_supplemental =

| PubChem =

| PubChemSubstance =

| IUPHAR_ligand =

| DrugBank =

| ChemSpiderID =

| UNII =

| KEGG =

| ChEBI =

| ChEMBL =

| synonyms =

}}

{{anchor|1=Monoclonal antibody drugs}}

• {{para|type|mab}}

This form the box uses parameters:

| type = mab

| mab_type =

| source =

| target =

For example Catumaxomab:

{{Infobox drug

| drug_name = Catumaxomab

| type = mab

| mab_type = 3funct

| source = axo

| target = EpCAM, CD3

}}

| type = mab

| mab_type = 3funct

| source = axo

| target = EpCAM, CD3

mab_type defines one of the following types of antibody or antibody fragment:

|-

| mab || Whole antibody

|-

| Fab || Fab fragment

|-

| F(ab')2 || F(ab')₂ fragment

|-

| Fab' || Fab' fragment

|-

| scFv || Single-chain variable fragment

|-

| di-scFv || Di-single-chain variable fragment

|-

| sdAb || Single domain antibody

|-

| 3funct || Trifunctional antibody

|-

| clFab || Chemically linked Fab

|-

| BiTE || Bi-specific T-cell engager

|}

source is the species on which the protein sequence of the antibody is based:

|-

| a || Rat

|-

| e || Hamster

|-

| i || Primate

|-

| o || Mouse

|-

| u || Human

|-

| xi/a, xi/e, etc. || Chimeric (rat/human) etc.

|-

| xi || Chimeric [generic, use only if values above are not applicable]

|-

| zu/a, zu/e, etc. || Humanized (from rat) etc.

|-

| zu || Humanized [generic, use only if values above are not applicable]

|-

| xizu/a, xizu/e, etc. || Chimeric/humanized hybrid (rat/human) etc.

|-

| xizu || Chimeric/humanized hybrid [generic, use only if values above are not applicable]

|-

| axo || Rat/mouse hybrid

|}

target is the antigen at which the antibody is directed. This parameter takes free text as value, preferably including a wikilink such as {{para|target|TNF-α}}.

The drug name is followed by a "?" linked to Nomenclature of monoclonal antibodies, saving the need to explain how each monoclonal antibody has been named.

Shortened Monoclonal antibody form:

{{Infobox drug

| type = mab

| image =

| image_class =

| alt =

| caption =

| mab_type =

| source =

| target =

| pronounce =

| tradename =

| Drugs.com =

| MedlinePlus =

| pregnancy_AU =

| pregnancy_AU_comment =

| pregnancy_category=

| routes_of_administration =

| ATC_prefix =

| ATC_suffix =

| legal_AU =

| legal_AU_comment =

| legal_BR =

| legal_BR_comment =

| legal_CA =

| legal_CA_comment =

| legal_DE =

| legal_DE_comment =

| legal_NZ =

| legal_NZ_comment =

| legal_UK =

| legal_UK_comment =

| legal_US =

| legal_US_comment =

| legal_EU =

| legal_EU_comment =

| legal_UN =

| legal_UN_comment =

| legal_status =

| bioavailability =

| protein_bound =

| metabolism =

| metabolites =

| onset =

| elimination_half-life =

| duration_of_action=

| excretion =

| CAS_number =

| PubChem =

| DrugBank =

| KEGG =

}}

• {{para|type|vaccine}}

This allows the alternative parameters of the vaccine_type and target to be specified:

• target can be any text. Can be used to link to a specific article
• vaccine_type from the defined list of options as described at Vaccine#Types, the infobox will provide standardised display and links as follows:

Where a vaccination product protects against more than one agent, please use the combination form of this infobox with type=combo (per #Combination products), and each classX=Vaccine.

Shortened Vaccine form:

{{Infobox drug

| drug_name =

| type = vaccine

| image =

| image_class =

| alt =

| caption =

| target =

| vaccine_type =

| pronounce =

| tradename =

| Drugs.com =

| MedlinePlus =

| pregnancy_AU =

| pregnancy_AU_comment =

| pregnancy_category=

| routes_of_administration =

| ATCvet =

| ATC_prefix =

| ATC_suffix =

| legal_AU =

| legal_AU_comment =

| legal_BR =

| legal_BR_comment =

| legal_CA =

| legal_CA_comment =

| legal_DE =

| legal_DE_comment =

| legal_NZ =

| legal_NZ_comment =

| legal_UK =

| legal_UK_comment =

| legal_US =

| legal_US_comment =

| legal_EU =

| legal_EU_comment =

| legal_UN =

| legal_UN_comment =

| legal_status =

| CAS_number =

| PubChem =

| DrugBank =

}}

Full Vaccine template with extended fields:

{{Infobox drug

| drug_name =

| type = vaccine

| image =

| image_class =

| alt =

| width =

| caption =

| image2 =

| image_class2 =

| alt2 =

| width2 =

| caption2 =

| target =

| vaccine_type =

| pronounce =

| tradename =

| Drugs.com =

| MedlinePlus =

| licence_CA =

| licence_EU =

| DailyMedID =

| licence_US =

| pregnancy_AU =

| pregnancy_AU_comment =

| pregnancy_category=

| routes_of_administration =

| ATCvet =

| ATC_prefix =

| ATC_suffix =

| legal_AU =

| legal_AU_comment =

| legal_BR =

| legal_BR_comment =

| legal_CA =

| legal_CA_comment =

| legal_DE =

| legal_DE_comment =

| legal_NZ =

| legal_NZ_comment =

| legal_UK =

| legal_UK_comment =

| legal_US =

| legal_US_comment =

| legal_EU =

| legal_EU_comment =

| legal_UN =

| legal_UN_comment =

| legal_status =

| CAS_number =

| CAS_supplemental =

| PubChem =

| PubChemSubstance =

| IUPHAR_ligand =

| DrugBank =

| ChemSpiderID =

| UNII =

| KEGG =

| ChEBI =

| ChEMBL =

| NIAID_ChemDB =

}}

{{collapse top|title = {{tlf|Infobox drug}} parameter list| bg=#eaeaea}}

{{Infobox drug/doc/parameter list}}

{{collapse bottom}}

{{infobox drug|drug_name=Aspirin|image=Blank file.xcf|width=5px}}

By default, the title of the infobox is the article title. You can overwrite that using

{{para|drug_name}}.

Per the Manual of Style, the infobox title must be the International nonproprietary name (INN). There is a tooltip text referring to INN.

When, for some reason, the title is not the INN, the correct INN can be added as a subtitle using {{para|INN}}

{{infobox drug|drug_name=Heroin| INN=Diamorphine|image=Blank file.xcf|width=5px}}

| drug_name = Heroin

| INN = Diamorphine

When the drug has no INN at all, setting {{para|INN|none}} will suppress the tooltip text mentioning INN.

:See also #Names and identifiers

You can use the image to provide an illustration. A caption can be added. The alt parameter is a textual description of the image, and is shown in the 'tooltip' and read by visually impaired readers (more in WP:ALT). Parameter width sets the width in px; default width is 200px. CSS classes are applied through the image_class parameters.

Image classes default to dark_mode_safe defined at Template:Infobox drug/styles.css. This class applies a light grey background to images when dark mode is active as a widely applicable fallback for dark images on transparent backgrounds like structural diagrams. Setting an image_class parameter overrides this default class. For example, setting image_class = skin-invert-image results in no grey background with the colours of the first image inverted.

{{Infobox drug

| drug_name = demo: image

| image = Aspirin-skeletal.svg

| caption = structure

| alt = Molecule of aspirin

| width = 125

| image_class = skin-invert-image

}}

| image = Aspirin-skeletal.svg

| caption = structure

| alt = Molecule of aspirin

| width = 125

| image_class = skin-invert-image

{{clear}}

A second image can be added using image2:

| image2 =

| caption2 =

| alt2 =

| width2 =

| image_class2 =

Also a side-by-side pair of images can be added (with single caption):

| imageL =

| widthL =

| altL =

| image_classL =

| imageR =

| widthR =

| altR =

| image_classR =

| captionLR =

See also #Other chemical data input for the 3D model by Jmol (an external link).

| tradename =

| Drugs.com =

| MedlinePlus =

| routes_of_administration =

• tradename – comma separated list of trade names by the originator (no generics, not more than three names)
• Drugs.com – link to Drugs.com monograph
• MedlinePlus – MedlinePlus drug accession number

:See also pregnancy category, documentation for extensive documentation

Pregnancy Categorisation has been previously declared using just the pregnancy_category parameter with a variety of markup styles used to indicate various countries and their classifications. Alternatively pregnancy_AU may be set to the fixed categories. For Australia values permitted are: A, B1, B2, B3, C, D or X (note if just set to 'B' then B? is shown). Pregnancy categories are no longer used in the US.

Note the UK does not have official designated categorisations, but has both a variety of standard phrases with explanatory qualifications, plus many individual descriptions. The generic {{para|pregnancy_category}} accepts any text, and may be used with such country-specific information (non AU or US).

{{Infobox drug

| drug_name=Demo pregnancy

| pregnancy_AU = B1

| pregnancy_AU_comment = {{dummy reference}}

| pregnancy_category = Used in pregnancy against PIH

}}

| pregnancy_AU = B1

| pregnancy_AU_comment = ...

| pregnancy_category = Used in pregnancy against PIH

Optional parameters Dependence liability and Addiction_liability allow opioids or benzodiazepines to be flagged with the risk of becoming dependent/addicted upon them, although in many cases this may be somewhat subjective. Drugs should be rated as Low, Medium, High or Extremely high:

| dependency_liability = High

| addiction_liability = High

{{hatnote|1=In British English, "licence" is the noun, "to license" is the verb. In US English, the noun is "license" (more in {{section link||ENGVAR}} below)}}

There are three major licensing authorities that make drug information online accessible: the European Medicines Agency (EMA, EU), and the Food and Drug Administration (FDA, US).

The FDA "Label Information" and the EMA "Product Information", where available, are very detailed. There is material aimed at the professional and also plain-English consumer information. These are excellent reliable source for article information but also contains much that makes it a worthwhile "External link" since there is no way one can include all the info. Both sites work when using the brand name of the drug but the FDA site also allows searches with the generic name (active ingredient), which lists generic variants where they are licensed. Health Canada's site operates similarly to the FDA's site, with Canada-specific drug monographs and other information. The DailyMed site is a more user-friendly repository of primarily labeling information. For all sites, the use of the generic name of the drug is preferred whenever possible as this will list all brand and generic forms of the drug.

| licence_EU =

| DailyMedID =

| licence_US =

:{{para|licence_EU|yes}} will create a link to the EMA site, using the INN (i.e., INN, drug_name or article title). When the EMA used INN is different, enter its INN in {{para|INN_EMA}}.

Lists of products and the parameter term to use may be easily searched for:

• European Public Assessment Reports: [http://www.ema.europa.eu/sitemap.htm SiteMap], authorised products A–Z: [http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/landing/epar_search.jsp human], [http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/landing/vet_epar_search.jsp veterinary]
• Licence EU (EMA): any input in {{para|licence_EU}} will give a link to the EMA page for the active substance (INN).
• Drugs@FDA [http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?fuseaction=Search.Search_Drug_Name Search by Drug Name or Active Ingredient]
• : Where items are composed of more than one word, DailyMedID and licence_US require an underscore '_' in place of any spaces; e.g. Acyclovir_sodium.

| class = any text

The drug class designates the family that this drug belongs to. Typically the chemical class (e.g., benzodiazepine), mechanism of action (e.g., beta blocker), mode of action (e.g., diuretic), and/or therapeutic class (e.g., analgesic). Hence this field may contain more than one drug class if appropriate (each preferably wiki linked).

{{see|Wikipedia:WikiProject Pharmacology/Style guide#Use ATC codes}}

Where the drug is not included in ATC coding system (as opposed to its value just not been entered into the template) then set ATC_prefix to 'none', and the article is automatically added to :Category:Drugs not assigned an ATC code:

| ATC_prefix = none

Additional ATC(vet) may be included with the optional {{para|ATC_supplemental}} parameter as a comma-separated list. ATC templates may be used to have these additional codes link to the relevant databases:

| ATC_supplemental ={{ATC|M02|AA15}}, {{ATCvet|S01|BC03}}

Adds the following linked codes:

:For ATC – {{ATC|M02|AA15}}, {{ATCvet|S01|BC03}}

Veterinary drugs are placed in a slightly different classification system, ATCvet. The code may be specified as ATCvet by setting the parameter ATCvet to 'yes'. Do not include the leading 'Q' in ATC_prefix:

| ATCvet = yes

| ATC_prefix = N05

| ATC_suffix = AX90

When the ATCvet code happens to be the same as the ATC for a mainly human drug, it is usually a better idea to just provide the ATC in the infobox.

:See also: {{tl|Infobox drug/legal status}} for extensive documentation.

Legal status allows to specify which controlling acts are active in various countries and organisations. Available parameters are {{para|1=legal_AU, legal_BR, legal_CA, legal_DE, legal_NZ, legal_UK, legal_US, legal_EU, legal_UN}}, and links are provided for standard input. Also, the parameters can have the suffix {{para|1=..._comment}}.

Also available is {{para|legal_status}}, which is general and allows any text. When using this parameter, consider adding geographical information on where this is law.

{{infobox drug

| drug_name=Example

| legal_AU = S2

| legal_AU_comment = any text

| legal_BR = A1

| legal_BR_comment = any text

| legal_CA =

| legal_DE =

| legal_UK = gsl

| legal_US = Schedule II

| legal_US_comment = and OTC in Oregon

| legal_EU =

| legal_UN =

| legal_NZ =

| legal_status = Not marketed in Asia

}}

| legal_AU = S2

| legal_AU_comment = any text

| legal_BR = A1

| legal_BR_comment = any text

| legal_CA =

| legal_DE =

| legal_UK = gsl

| legal_US = Schedule II

| legal_US_comment = and OTC in Oregon

| legal_EU =

| legal_UN =

| legal_NZ =

| legal_status = Not marketed in Asia

Note: if a drug is restricted everywhere to prescription-only, please set legal_status = Rx-only rather than similarly define for each and every country. {{para|legal_status|Rx-only}} is specifically recognised and shows as {{Infobox drug/legal status|legal_status=Rx-only}}

Use wikilinks for values that the general reader might not understand (e. g. hepatic, CYP3A4, intraperitoneal).

| bioavailability =

| protein_bound =

| metabolism =

| metabolites =

| onset =

| elimination_half-life =

| duration_of_action=

| excretion =

{{Infobox drug/doc/names and identifiers|state=collapsed}}

Some countries have a variant INN name defined. For example, USAN (US) uses "acetaminophen" for paracetamol. Use {{para|1=AAN= BAN= JAN= USAN}} when a name is different from the INN (do not repeat INN).

{{para|CAS_number}}

Additional CAS codes may be included with optional {{para|CAS_supplement}} parameters in a comma-separated lists. CAS templates may be used to have these additional codes link to the relevant databases:

| CAS_supplemental ={{CAS|427-51-0}} (acetate)

Adds the following linked codes:

:For CAS – {{CAS|427-51-0}} (acetate)

• See also: Second identifiers and indexes

The DrugBank primary accession number (consisting of a 2 letter prefix (DB) and a 5 number suffix). Secondary accession numbers with a 4 letter suffix (APRD, EXPT, BIOD, NUTR) should not normally be used.

When available, the PubChem compound identifier (CID) should be used because it is unique for each chemical compound:

| PubChem = 4091

Make sure you choose the right CID: Often PubChem compound entries differ only very slightly, for example by an additional hydratation water or by a carbon atom with unspecified stereochemistry.

If no CID is available, which is usually the case when there is no structural information on PubChem, you may use one of the substance identifiers (SIDs):

| PubChemSubstance = 10099

{{Para|DTXSID}} is the identifier for the CompTox Chemicals Dashboard (by EPA). For example: {{para|DTXSID|DTXSID5020108}} for [https://comptox.epa.gov/dashboard/dsstoxdb/results?search=DTXSID5020108 aspirin].

By default, the value is read from Wikidata {{property|P3117}}. This can be overwritten by entering a value for {{Para|DTXSID}}. Setting {{Para|DTXSID|none}} suppresses the Wikidata value (no show).

{{anchor|1=Second identifier}}

{{collapse top|title=Using second identifiers|bg=#ddd}}

All identifiers can have a second, index-2 identifier, representing a second chemical substance. For example, {{para|CAS_number|536-71-0}}, {{para|CAS_number2|908-54-3}}.

Additionally, {{para|index_label}} and {{para|index2_label}} can be used to prefix (clarify) both substances.

• For combination drugs, better use {{para|type|combo}} settings: see #Combination of chemicals.

;Demo

{{infobox drug

| drug_name=Demo indexes
(Diminazen)

| index_label=

| index2_label=aceturate

| index_comment = standard

| index2_comment = see aceturic acid

| CAS_number = 536-71-0

| CAS_number2 = 908-54-3

| PubChem = 2354

| UNII = Y5G36EEA5Z

| UNII2 = JI8SAD85NO

| DrugBank =

}}

• When used, the indexes {{angbr|blank}} and 2 are used consistently for two substances (so, all #2 identifiers refer to the same alternate substance).
• When index 2 is used, consider adding {{para|index_label}} and {{para|index2_label}} prefixes, to appear before every identifier.
• These index prefixes can be explained using {{para|index_comment}}, {{para|index2_comment}} which will show in top.

{{clear}}

{{collapse bottom}}

Entering the chemical formula per element:

| C= | H= | Ag= | Al= | As= | Au= | B= | Bi= | Br= | Ca= | Cl= | Co= | F= | Fe= | Gd= | I=

| K= | Li= | Mg= | Mn= | N= | Na= | O= | P= | Pt= | S= | Sb= | Se= | Sr= | Tc= | Zn=

| charge=

| chemical_formula_ref =

| chemical_formula_comment =

E.g.

| C=2 | H=6 | O=1 | charge=2-

gives

:Formula {{Chembox Elements/molecular formula| C=2 | H=6 | O=1 | charge=2-}}

This is called the empirical form, the most simple form. Entered this way, the elements are ordered in the Hill notation order: When C is present, C_xH_y in front and the others alphabetically Ar ... Zr. When a molecular formula or structural formula is known, that one should be entered in {{para|chemical_formula}} (consider using {{tl|Chem2}}).

You can provide the chemical formula as fixed

| chemical_formula =

| chemical_formula_ref =

| chemical_formula_comment =

todo: example

;Molar mass

When the chemical formula is entered as |C=2 |O=1 |H=6, the molar mass is calculated and presented. This value can be overwritten by using {{para|molecular_weight}} (sic). For more information, see {{tl|Chem molar mass}}.

Additional chemical data fields are SMILES and standard InChI (optionally oncluding a comment and standard InChIKey).

| SMILES =

| Jmol =

| StdInChI =

| StdInChI_comment =

| StdInChIKey =

;The Jmol 3D model

When {{para|SMILES}} has input, the template automatically adds an external link to the Jmol 3D molecule model.

• {{para|Jmol|none}} will suppress (hide) that data row ("none" is case-sensitive).
• {{para|Jmol|{{angbr|some SMILES string}}}} will link to the 3D-model of that string (i.e. overwriting {{para|SMILES}} input). SMILES will show its input unchanged.

This is entirely optional data, and for most drugs is not helpful to the wider readership. Only include if information of particular interest for the drug as to its chemical properties (e.g. in its manufacture or as an important chemical in its own right, e.g. Aspirin).

| density =

| density_notes =

| melting_point =

| boiling_point =

| solubility =

| sol_units =

| specific_rotation =

The template will add the following to the numeric values provided:

• Density – added 'g/cm³'
• Melting or Boiling points – added '°C' along with calculated converted value in °F.
• Solubility – If sol_units is specified, it will follow the solubility value; otherwise " mg/mL (20 °C)" will follow. This is to accommodate multiple solubility values at different temps, other units, etc.

Hence:

| solubility = 100

| sol_units =  g/L ({{Convert|212|F|C}})

gives:

:Solubility 100 g/L (212 °F (100 °C))

In addition, where the melting point occurs over a range of temperatures, use melting_high for the upper value.

Hence:

| melting_point = 100

| melting_high = 104

gives:

:Melting point 100–104 °C (212–219 °F)

Comments can be added to the melting and boiling point entries using melting_notes and boiling_notes.

Hence:

| boiling_point = 100

| boiling_notes = (sublimes)

gives:

:Boiling point 100 °C (212 °F) (sublimes)

Endogenous drugs (neurotransmitters, neurohormones, or hormones) are a single chemical ({{para|type|<blank>}}). Their special data is shown in section "Physiological data".

Notes: input {{para|metabolism}} is shared with pharmacokinetic data, and will show in each of these sections that has more data (context).

When this section has input, sections Clinical data and Legal data should be empty.

| source_tissues =

| target_tissues =

| receptors =

| agonists =

| antagonists =

| precursor =

| biosynthesis =

| metabolism =

Example:

{{Infobox drug

| drug_name = Oxytocin

| source_tissues = posterior pituitary

| target_tissues = central nervous system

| receptors = oxytocin receptor

| agonists = carbetocin, demoxytocin

| antagonists = atosiban, epelsiban

| precursor = oxytocin-neurophysin 1

| biosynthesis = magnolysin

| metabolism = oxytocinase

}}

| drug_name = Oxytocin

| source_tissues = posterior pituitary

| target_tissues = central nervous system

| receptors = oxytocin receptor

| agonists = carbetocin, demoxytocin

| antagonists = atosiban, epelsiban

| precursor = oxytocin-neurophysin 1

| biosynthesis = magnolysin

| metabolism = oxytocinase

• Categorised: {{Category link with count|Drugs that are a physiological drug}}

| gt_target_gene =

| gt_vector =

| gt_nucleic_acid_type =

| gt_editing_method =

| gt_delivery_method =

Example:

{{Infobox drug

| drug_name = Voretigene neparvovec

| gt_target_gene = RPE65

| gt_vector = adenovirus serotype 2

| gt_nucleic_acid_type = [not applicable here]

| gt_editing_method = [not applicable here]

| gt_delivery_method = [not applicable here]

}}

{{Infobox drug

| drug_name = Voretigene neparvovec

| gt_target_gene = RPE65

| gt_vector = adenovirus serotype 2

| gt_nucleic_acid_type = [not applicable here]

| gt_editing_method = [not applicable here]

| gt_delivery_method = [not applicable here]

}}

• Categorised: {{Category link with count|Drugs that are a gene therapy}}

{{Uses Wikidata|P628|P2566|P3117}}

The template reads and shows the E number, ECHA InfoCard ID and Comptox DTXSID ID from Wikidata. If there is no value present, no data is shown.

See also {{cl|Chemical compounds and Wikidata}}.

Seven identifying parameters like {{para|CAS_number}} are tracked in a WP:Drugbox data validation process. A bot adds parameters like

{{para|verifiedrevid}} and {{para|CAS_number_Ref|{{cascite|correct}}}}. See also {{tl|cascite}} documentation.

The word "License/Licence" can be spelled in two ways, generally by English variant en-UK or en-US. Per Manual of Style:ENGVAR, this chosen regional language should be consistent throughout the whole article.

The default spelling in the infobox is en-US: "LicenSe". Setting {{para|engvar|2=en-AU, en-CA, en-EI, en-NZ, en-UK}} spells "LicenCe". Again, this should follow the article's overall language.

Independently from this, each parameter {{para|licence_US}} or {{para|license_US}} can be used for the same input point. This is for ease of editing, but does not change the spelling of "Licence/License" that will show.

A {{para|type}} can use specific headers.

| type=mab

| type=vaccine

| type=combo

| type=

:Types are listed in {{cl|Drugs by type}}

Dependent sections:

{{Infobox drug/doc/type-conditional sections|state=collapsed}}

• Eprinomectin, Hib vaccine, Sarafotoxin (3 boxes), Valproate, Varespladib

:(checked manually using WP:AWB, 5/8275, 20-12-2021)

{{collapse top|title=TemplateData|bg=#ddd}}

{{TemplateData header|noheader=1}}

{

"description": "This infobox provides information over-the-counter and prescription-only drugs. It can be used for single drugs, combination products, monoclonal antibodies and vaccines.",

"format": "{{_\n| _ = _\n}}",

"params": {

"drug_name": {

"label": "Drug name",

"description": "Name of the drug, medication, or vaccine, including combination drugs. The article title will be used if this is left blank.",

"type": "string",

"suggested": true

},

"image": {

"label": "Image",

"example": "Aspirin-Wireframe.svg",

"type": "wiki-file-name",

"suggested": true,

"description": "An imagine that will be displayed in the infobox"

},

"image_class": {

"label": "Image CSS class",

"example": "skin-invert-image",

"type": "string",

"suggested": true,

"description": "CSS class for the image. Options: skin-invert-image / bg-transparent / dark_mode_safe"

},

"width": {

"label": "Image width",

"description": "Sets the width of the image. Default is 200px",

"example": "300px",

"type": "number",

"default": "200px"

},

"alt": {

"label": "Alt text",

"description": "Describe the appearance of the image, for people who cannot see the image",

"example": "Two scored pills, one pink with a large numeral 1 stamped in the surface, and the other tan and marked with a large numeral 3",

"type": "string",

"suggested": true

},

"image2": {},

"image_class2": {},

"width2": {},

"alt2": {},

"caption": {

"label": "Caption",

"description": "A caption for the image",

"example": "Warfarin pills. The colors and numbers indicate different doses.",

"type": "string",

"suggested": true

},

"imageL": {},

"image_classL": {},

"imageR": {},

"image_classR": {},

"widthL": {},

"altL": {},

"widthR": {},

"altR": {},

"captionLR": {},

"type": {

"description": "Drug type, can be left (for single chemical), \"vaccine\", \"combo\" (combination of drugs), and \"mab\" (monoclonal antibody)",

"suggested": true,

"example": "combo",

"type": "string"

},

"IUPAC_name": {

"description": "Systematic IUPAC name"

},

"target": {

"label": "Target disease (vaccine or mab)"

},

"vaccine_type": {},

"mab_type": {},

"source": {},

"component1": {},

"class1": {},

"component2": {},

"class2": {},

"component3": {},

"class3": {},

"component4": {},

"class4": {},

"component5": {},

"class5": {},

"DailyMedID": {},

"Drugs.com": {},

"MedlinePlus": {

"suggested": true

},

"dependency_liability": {},

"addiction_liability": {},

"legal_AU_comment": {},

"legal_AU": {

"description": "Schedule 2, ... Schedule 9 (or: s2, ... s9)",

"example": "S7",

"type": "line"

},

"legal_BR_comment": {},

"legal_BR": {

"description": "OTC, A1, A2, A3, B1, B2, C1, C2, C3, C5, D1, D2, E, F1, F2, F3, F4",

"example": "A1"

},

"legal_CA_comment": {},

"legal_CA": {

"description": "OTC, Rx or Rx-only, Schedule I, ... Schedule VIII",

"example": "Schedule V"

},

"legal_DE_comment": {},

"legal_DE": {

"example": "Anlage I, Anlage II, Anlage III",

"type": "line"

},

"legal_EU_comment": {},

"legal_EU": {},

"legal_NZ_comment": {},

"legal_NZ": {},

"legal_UK_comment": {},

"legal_UK": {},

"legal_UN_comment": {},

"legal_UN": {},

"legal_US_comment": {},

"legal_US": {},

"legal_status": {

"description": "For general use and/or countries not specified within template",

"example": "'Available over-the-counter'; OR 'Prescription drug'",

"type": "string",

"suggested": true

},

"licence_EU": {

"suggested": true

},

"pregnancy_AU_comment": {},

"pregnancy_AU": {

"label": "Pregnancy (Australia)",

"description": "Pregnancy category in Australia. Use one of these codes: A, B1, B2, B3, C, D, X",

"example": "C",

"type": "line",

"suggested": true

},

"pregnancy_category": {

"label": "Pregnancy category",

"description": "General categorization regarding pregnant or lactating women",

"type": "string",

"suggested": true

},

"routes_of_administration": {

"description": "A medication administration route",

"example": "oral, sublingual, intravenous, intramuscular, etc. ",

"type": "string"

},

"tradename": {

"description": "Trade name (or brand name), not to be confused with other known names",

"example": "\"Tylenol\" instead of paracetamol (acetaminophen)"

},

"pronounce": {},

"pronounce comment": {},

"pronounce ref": {},

"pronounce 2": {

"deprecated": "pronounce should refer to title (drug name). Otherwise, add explaining text. There is no name that this #2 paramteer is associated with."

},

"licence_US": {

"suggested": true

},

"bioavailability": {},

"protein_bound": {},

"metabolism": {},

"metabolites": {},

"onset": {

"description": "Onset of action. The length of time it takes for a medicine to start to work. Use appropriate unit of time. If relevant, be specific about the routes of administration"

},

"elimination_half-life": {

"description": "Elimination half-life (biological half-life)"

},

"duration_of_action": {

"description": "Duration of action"

},

"excretion": {},

"synonyms": {

"description": "Other known names that are not trade names (or brand names). It will be displayed next to \"Other names\" ",

"type": "string"

},

"AAN": {},

"BAN": {},

"JAN": {},

"USAN": {},

"PDB_ligand": {},

"ATCvet": {},

"ATC_prefix": {},

"ATC_supplemental": {},

"CAS_number": {},

"ChEBI": {},

"ChEMBL": {},

"ChemSpiderID": {},

"DrugBank": {

"label": "DrugBank",

"description": "DrugBank identification number",

"example": "DB01060",

"suggested": true

},

"IUPHAR_ligand": {},

"KEGG": {},

"NIAID_ChemDB": {},

"PubChem": {},

"PubChemSubstance": {},

"UNII": {},

"CAS_number_Ref": {},

"CAS_supplemental": {},

"ATC_suffix": {},

"DrugBank_Ref": {},

"ChemSpiderID_Ref": {},

"UNII_Ref": {},

"KEGG_Ref": {},

"ChEBI_Ref": {},

"ChEMBL_Ref": {},

"Ac": {},

"Ag": {},

"Al": {},

"Am": {},

"Ar": {},

"As": {},

"At": {},

"Au": {},

"B": {},

"Ba": {},

"Be": {},

"Bh": {},

"Bi": {},

"Bk": {},

"Br": {},

"C": {},

"Ca": {},

"Cd": {},

"Ce": {},

"Cf": {},

"Cl": {},

"Cm": {},

"Cn": {},

"Co": {},

"Cr": {},

"Cs": {},

"Cu": {},

"Db": {},

"Ds": {},

"Dy": {},

"Er": {},

"Es": {},

"Eu": {},

"F": {},

"Fe": {},

"Fl": {},

"Fm": {},

"Fr": {},

"Ga": {},

"Gd": {},

"Ge": {},

"H": {},

"He": {},

"Hf": {},

"Hg": {},

"Ho": {},

"Hs": {},

"I": {},

"In": {},

"Ir": {},

"K": {},

"Kr": {},

"La": {},

"Li": {},

"Lr": {},

"Lu": {},

"Lv": {},

"Md": {},

"Mg": {},

"Mn": {},

"Mo": {},

"Mt": {},

"N": {},

"Na": {},

"Nb": {},

"Nd": {},

"Ne": {},

"Ni": {},

"No": {},

"Np": {},

"O": {},

"Os": {},

"P": {},

"Pa": {},

"Pb": {},

"Pd": {},

"Pm": {},

"Po": {},

"Pr": {},

"Pt": {},

"Pu": {},

"Ra": {},

"Rb": {},

"Re": {},

"Rf": {},

"Rg": {},

"Rh": {},

"Rn": {},

"Ru": {},

"S": {},

"Sb": {},

"Sc": {},

"Se": {},

"Sg": {},

"Si": {},

"Sm": {},

"Sn": {},

"Sr": {},

"Ta": {},

"Tb": {},

"Tc": {},

"Te": {},

"Th": {},

"Ti": {},

"Tl": {},

"Tm": {},

"U": {},

"Uuo": {},

"Uup": {},

"Uus": {},

"Uut": {},

"V": {},

"W": {},

"Xe": {},

"Y": {},

"Yb": {},

"Zn": {},

"Zr": {},

"chemical_formula": {},

"chemical_formula_comment": {},

"molecular_weight": {},

"molecular_weight_round": {},

"molecular_weight_unit": {},

"molecular_weight_comment": {},

"SMILES": {

"aliases": [

"smiles"

],

"description": "Simplified Molecular-Input Line-entry System"

},

"StdInChI": {},

"charge": {

"description": "Electrical charge of the molecule (when formula is entered by atom numbers)",

"example": "2+",

"type": "string"

},

"chemical_formula_ref": {},

"molecular_weight_ref": {},

"StdInChI_Ref": {},

"StdInChI_comment": {},

"StdInChIKey": {},

"StdInChIKey_Ref": {},

"density": {},

"density_notes": {},

"melting_point": {},

"boiling_point": {},

"solubility": {},

"specific_rotation": {},

"melting_high": {},

"melting_notes": {},

"boiling_high": {},

"boiling_notes": {},

"data_page": {},

"verifiedrevid": {},

"Verifiedfields": {

"description": "Bot-maintained tracking parameter",

"type": "string"

},

"Watchedfields": {

"description": "Bot-maintained tracking parameter"

},

"gt_vector": {},

"gt_nucleic_acid_type": {},

"gt_editing_method": {},

"gt_delivery_method": {},

"INN": {

"description": "International Nonproprietary Name (INN)",

"type": "string",

"suggested": true

},

"caption2": {},

"gt_target_gene": {},

"licence_CA": {},

"license_CA": {},

"license_EU": {},

"license_US": {},

"class": {},

"ATC_prefix2": {},

"ATC_supplemental2": {},

"pronounce_comment": {},

"pronounce_ref": {},

"engvar": {},

"INN_EMA": {},

"index_label": {},

"index2_label": {},

"ATC_suffix2": {},

"sources": {},

"targets": {},

"receptors": {},

"agonists": {},

"antagonists": {},

"precursor": {},

"biosynthesis": {},

"source_tissues": {},

"target_tissues": {},

"DTXSID": {},

"index_comment": {},

"index2_comment": {},

"CAS_number2": {},

"CAS_supplemental2": {},

"CAS_number2_Ref": {},

"PubChem2": {},

"PubChemSubstance2": {},

"IUPHAR_ligand2": {},

"DrugBank2": {},

"DrugBank2_Ref": {},

"ChemSpiderID2": {},

"ChemSpiderID2_Ref": {},

"UNIIRef": {},

"UNII2": {},

"UNII2_Ref": {},

"KEGG2": {},

"KEGG2_Ref": {},

"ChEBI2": {},

"ChEBI2_Ref": {},

"ChEMBL2": {},

"ChEMBL2_Ref": {},

"NIAID_ChemDB2": {},

"PDB_ligand2": {},

"DTXSID2": {},

"D": {},

"Mc": {},

"Nh": {},

"Og": {},

"Ts": {},

"chirality": {},

"Jmol": {},

"SMILES2": {},

"Jmol2": {},

"sol_units": {},

"StdInChI2": {},

"StdInChI2_Ref": {},

"StdInChIKey2": {},

"StdInChIKey2_Ref": {},

"QID": {},

"QID2": {},

"smiles2": {}

},

"paramOrder": [

"drug_name",

"type",

"IUPAC_name",

"image",

"image_class",

"width",

"alt",

"caption",

"image2",

"image_class2",

"width2",

"alt2",

"imageL",

"image_classL",

"widthL",

"altL",

"imageR",

"image_classR",

"widthR",

"altR",

"captionLR",

"vaccine_type",

"mab_type",

"source",

"target",

"pronounce",

"pronounce comment",

"pronounce ref",

"pronounce 2",

"tradename",

"Drugs.com",

"component1",

"class1",

"component2",

"class2",

"component3",

"class3",

"component4",

"class4",

"component5",

"class5",

"MedlinePlus",

"licence_EU",

"licence_US",

"DailyMedID",

"pregnancy_AU",

"pregnancy_AU_comment",

"pregnancy_category",

"legal_AU",

"legal_AU_comment",

"legal_BR",

"legal_BR_comment",

"legal_CA",

"legal_CA_comment",

"legal_DE",

"legal_DE_comment",

"legal_EU",

"legal_EU_comment",

"legal_NZ",

"legal_NZ_comment",

"legal_UK",

"legal_UK_comment",

"legal_US",

"legal_US_comment",

"legal_UN",

"legal_UN_comment",

"legal_status",

"dependency_liability",

"addiction_liability",

"routes_of_administration",

"bioavailability",

"protein_bound",

"metabolism",

"metabolites",

"onset",

"elimination_half-life",

"duration_of_action",

"excretion",

"CAS_number",

"CAS_number_Ref",

"CAS_supplemental",

"ATCvet",

"ATC_prefix",

"ATC_suffix",

"ATC_supplemental",

"PubChem",

"PubChemSubstance",

"IUPHAR_ligand",

"DrugBank",

"DrugBank_Ref",

"ChemSpiderID",

"ChemSpiderID_Ref",

"UNII",

"UNII_Ref",

"KEGG",

"KEGG_Ref",

"ChEBI",

"ChEBI_Ref",

"ChEMBL",

"ChEMBL_Ref",

"NIAID_ChemDB",

"PDB_ligand",

"synonyms",

"AAN",

"BAN",

"JAN",

"USAN",

"chemical_formula",

"chemical_formula_comment",

"Ac",

"Ag",

"Al",

"Am",

"Ar",

"As",

"At",

"Au",

"B",

"Ba",

"Be",

"Bh",

"Bi",

"Bk",

"Br",

"C",

"Ca",

"Cd",

"Ce",

"Cf",

"Cl",

"Cm",

"Cn",

"Co",

"Cr",

"Cs",

"Cu",

"Db",

"Ds",

"Dy",

"Er",

"Es",

"Eu",

"F",

"Fe",

"Fl",

"Fm",

"Fr",

"Ga",

"Gd",

"Ge",

"H",

"He",

"Hf",

"Hg",

"Ho",

"Hs",

"I",

"In",

"Ir",

"K",

"Kr",

"La",

"Li",

"Lr",

"Lu",

"Lv",

"Md",

"Mg",

"Mn",

"Mo",

"Mt",

"N",

"Na",

"Nb",

"Nd",

"Ne",

"Ni",

"No",

"Np",

"O",

"Os",

"P",

"Pa",

"Pb",

"Pd",

"Pm",

"Po",

"Pr",

"Pt",

"Pu",

"Ra",

"Rb",

"Re",

"Rf",

"Rg",

"Rh",

"Rn",

"Ru",

"S",

"Sb",

"Sc",

"Se",

"Sg",

"Si",

"Sm",

"Sn",

"Sr",

"Ta",

"Tb",

"Tc",

"Te",

"Th",

"Ti",

"Tl",

"Tm",

"U",

"Uuo",

"Uup",

"Uus",

"Uut",

"V",

"W",

"Xe",

"Y",

"Yb",

"Zn",

"Zr",

"charge",

"molecular_weight",

"molecular_weight_round",

"molecular_weight_unit",

"molecular_weight_ref",

"molecular_weight_comment",

"SMILES",

"StdInChI",

"StdInChI_comment",

"StdInChIKey",

"StdInChIKey_Ref",

"density",

"density_notes",

"chemical_formula_ref",

"StdInChI_Ref",

"melting_point",

"melting_high",

"melting_notes",

"boiling_point",

"boiling_high",

"boiling_notes",

"solubility",

"specific_rotation",

"data_page",

"verifiedrevid",

"Verifiedfields",

"Watchedfields",

"gt_vector",

"gt_nucleic_acid_type",

"gt_editing_method",

"gt_delivery_method",

"INN",

"caption2",

"gt_target_gene",

"licence_CA",

"license_CA",

"license_EU",

"license_US",

"class",

"ATC_prefix2",

"ATC_supplemental2",

"pronounce_comment",

"pronounce_ref",

"engvar",

"INN_EMA",

"index_label",

"index2_label",

"ATC_suffix2",

"sources",

"targets",

"receptors",

"agonists",

"antagonists",

"precursor",

"biosynthesis",

"source_tissues",

"target_tissues",

"DTXSID",

"index_comment",

"index2_comment",

"CAS_number2",

"CAS_supplemental2",

"CAS_number2_Ref",

"PubChem2",

"PubChemSubstance2",

"IUPHAR_ligand2",

"DrugBank2",

"DrugBank2_Ref",

"ChemSpiderID2",

"ChemSpiderID2_Ref",

"UNIIRef",

"UNII2",

"UNII2_Ref",

"KEGG2",

"KEGG2_Ref",

"ChEBI2",

"ChEBI2_Ref",

"ChEMBL2",

"ChEMBL2_Ref",

"NIAID_ChemDB2",

"PDB_ligand2",

"DTXSID2",

"D",

"Mc",

"Nh",

"Og",

"Ts",

"chirality",

"Jmol",

"SMILES2",

"Jmol2",

"sol_units",

"StdInChI2",

"StdInChI2_Ref",

"StdInChIKey2",

"StdInChIKey2_Ref",

"QID",

"QID2",

"smiles2"

]

}

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• {{Category link with count|Pages using infobox drug with unknown parameters}}
• See also: {{cl|Infobox drug tracking categories}}

• {{tl|Infobox drug class}}
• {{tl|Infobox medical condition}}
• WP:PHARM for WikiProject page
• [https://alyw234237.github.io/wiki-drugbox-chembox-maker/ Wikipedia Drugbox and Chembox Maker]

{{sandbox other| |

Drug

Category:Infobox drug templates

Category:Infobox templates using Wikidata

{{PAGENAME}}

}}