Terpentedienyl-diphosphate synthase

{{short description|Type of enzyme}}

{{Infobox enzyme

| Name = Terpentedienyl-diphosphate synthase

| EC_number = 5.5.1.15

| CAS_number =

| GO_code =

| image =

| width =

| caption =

}}

Terpentedienyl-diphosphate synthase ({{EnzExplorer|5.5.1.15}}, terpentedienol diphosphate synthase, Cyc1, clerodadienyl diphosphate synthase) is an enzyme with systematic name terpentedienyl-diphosphate lyase (decyclizing).{{cite journal | vauthors = Dairi T, Hamano Y, Kuzuyama T, Itoh N, Furihata K, Seto H | title = Eubacterial diterpene cyclase genes essential for production of the isoprenoid antibiotic terpentecin | journal = Journal of Bacteriology | volume = 183 | issue = 20 | pages = 6085–94 | date = October 2001 | pmid = 11567009 | pmc = 99688 | doi = 10.1128/jb.183.20.6085-6094.2001 }}{{cite journal | vauthors = Hamano Y, Kuzuyama T, Itoh N, Furihata K, Seto H, Dairi T | title = Functional analysis of eubacterial diterpene cyclases responsible for biosynthesis of a diterpene antibiotic, terpentecin | journal = The Journal of Biological Chemistry | volume = 277 | issue = 40 | pages = 37098–104 | date = October 2002 | pmid = 12138123 | doi = 10.1074/jbc.m206382200 | doi-access = free }}{{cite journal | vauthors = Eguchi T, Dekishima Y, Hamano Y, Dairi T, Seto H, Kakinuma K | title = A new approach for the investigation of isoprenoid biosynthesis featuring pathway switching, deuterium hyperlabeling, and 1H NMR spectroscopy. The reaction mechanism of a novel streptomyces diterpene cyclase | journal = The Journal of Organic Chemistry | volume = 68 | issue = 14 | pages = 5433–8 | date = July 2003 | pmid = 12839434 | doi = 10.1021/jo026728a }} This enzyme catalyses the following chemical reaction

: geranylgeranyl diphosphate $\backslash rightleftharpoons$ terpentedienyl diphosphate

This enzyme requires Mg²⁺.