Thiolysis
Thiolysis is a reaction with a thiol (R-SH) that cleaves one compound into two.{{Cite journal |last1=Rao |first1=Balaji |last2=Simpson |first2=Carolyne |last3=Lin |first3=Hui |last4=Liang |first4=Liyuan |last5=Gu |first5=Baohua |date=2014-11-02 |title=Determination of thiol functional groups on bacteria and natural organic matter in environmental systems |url=https://pubmed.ncbi.nlm.nih.gov/24401410/ |journal=Talanta |volume=119 |pages=240–247 |doi=10.1016/j.talanta.2013.11.004 |issn=1873-3573 |pmid=24401410}} Thiolysis involves the addition of coenzyme A to one of the products. This reaction is similar to hydrolysis, which involves water instead of a thiol.{{Citation |last=Huang |first=Chun-Jen |title=5 - Advanced surface modification technologies for biosensors |date=2019-01-01 |url=https://www.sciencedirect.com/science/article/pii/B978012815409000005X |work=Chemical, Gas, and Biosensors for Internet of Things and Related Applications |pages=65–86 |editor-last=Mitsubayashi |editor-first=Kohji |publisher=Elsevier |language=en |isbn=978-0-12-815409-0 |access-date=2023-01-04 |editor2-last=Niwa |editor2-first=Osamu |editor3-last=Ueno |editor3-first=Yuko}} This reaction is seen in β-oxidation of fatty acids.{{Cite journal |last1=Adeva-Andany |first1=María M. |last2=Carneiro-Freire |first2=Natalia |last3=Seco-Filgueira |first3=Mónica |last4=Fernández-Fernández |first4=Carlos |last5=Mouriño-Bayolo |first5=David |date=2018-03-15 |title=Mitochondrial β-oxidation of saturated fatty acids in humans |url=https://pubmed.ncbi.nlm.nih.gov/29551309/ |journal=Mitochondrion |volume=46 |pages=73–90 |doi=10.1016/j.mito.2018.02.009 |issn=1872-8278 |pmid=29551309|s2cid=4303820 }} The depolymerisation of condensed tannins with the use of benzyl mercaptan as nucleophile is also called thiolysis.{{Cite journal |last1=Rubert-Nason |first1=Kennedy F. |last2=Lindroth |first2=Richard L. |date=2018-12-11 |title=Analysis of condensed tannins in Populus spp. using reversed phase UPLC-PDA-(-)esi-MS following thiolytic depolymerisation |url=https://pubmed.ncbi.nlm.nih.gov/30548354/ |journal=Phytochemical Analysis |volume=30 |issue=3 |pages=257–267 |doi=10.1002/pca.2810 |issn=1099-1565 |pmid=30548354|s2cid=56486911 }}
