Thistle Brook
{{short description|River in Buckinghamshire, England}}
{{Use dmy dates|date=April 2022}}
{{Infobox river
| name = Thistle Brook
| image = Thistle Brook - a tiddly dribble - geograph.org.uk - 1958010.jpg
| image_caption = The river near Wingrave
| source1_location = Mentmore, Aylesbury Vale
| source1_coordinates = {{coords|51.860899|-0.705015|format=dms|region:GB|display=inline}}
| mouth_location = River Thame, Aylesbury Vale
| mouth_coordinates = {{coords|51.842385|-0.736390|format=dms|region:GB|display=inline,title}}
| subdivision_type1 = Country
| subdivision_name1 = United Kingdom
| subdivision_type2 = County
| subdivision_name2 = Buckinghamshire
| map =
| map_caption =
| length =
| source1_elevation =
| discharge1_avg =
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}}
Thistle Brook is a short, minor river (brook) in Buckinghamshire, England that is a tributary to the River Thame.[https://www.francisfrith.com/thistle-brook/maps Old Maps of Thistle Brook, Buckinghamshire]. FrancisFrith.com. Retrieved 17 October 2021.
Located entirely in the Aylesbury Vale district, the brook rises in a farm (historically Thistlebrook farm)Great Britain. Ordnance Survey (1876) "[https://books.google.com/books?id=4NIHAAAAQAAJ Book of Reference to the Plan of the Parish of ...]". Eyre & Spottiswoode. p. 99. Retrieved 17 October 2021. in the civil parish of Mentmore, west of the village of Mentmore and south of Crafton, and flows south-west past Wingrave (located towards the north) and through a culvert under a road in the neighbourhood of Thistlebrook, before flowing into the River Thame.Ordnance Survey (2020) "181: Map of Chiltern Hills North". Ordnance Survey. Retrieved 17 October 2021.