Tiodazosin

{{Chembox

| ImageFile = Tiodazosin.svg

| ImageSize = 250px

| ImageAlt =

| PIN = [4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl][5-(methylsulfanyl)-1,3,4-oxadiazol-2-yl]methanone

| OtherNames =

|Section1={{Chembox Identifiers

| CASNo = 66969-81-1

| CASNo_Ref = {{cascite|correct|CAS}}

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = FQI0PYJ799

| PubChem = 60891

| ChemSpiderID = 54869

| StdInChI = 1S/C18H21N7O4S/c1-27-12-8-10-11(9-13(12)28-2)20-17(21-14(10)19)25-6-4-24(5-7-25)16(26)15-22-23-18(29-15)30-3/h8-9H,4-7H2,1-3H3,(H2,19,20,21)

| StdInChIKey = MULPYFRDYRZMDS-UHFFFAOYSA-N

| SMILES = COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=NN=C(O4)SC)N)OC}}

|Section2={{Chembox Properties

| C=18 | H=21 | N=7 | O=4 | S=1

| Appearance =

| Density =

| MeltingPt =

| BoilingPt =

| Solubility = }}

|Section3={{Chembox Hazards

| MainHazards =

| FlashPt =

| AutoignitionPt = }}

}}

Tiodazosin is an α1-adrenergic receptor antagonist.{{cite journal|pmid=1681068|year=1991|last1=Chiang|first1=J|last2=Hermodsson|first2=G|last3=Oie|first3=S|title=The effect of alpha 1-acid glycoprotein on the pharmacological activity of alpha 1-adrenergic antagonists in rabbit aortic strips|volume=43|issue=8|pages=540–7|journal=The Journal of Pharmacy and Pharmacology|doi=10.1111/j.2042-7158.1991.tb03533.x|s2cid=97860582}}

See also

References

{{Reflist}}

{{Adrenergic receptor modulators}}

Category:Alpha-1 blockers

Category:Quinazolines

Category:Oxadiazoles

Category:Thioethers

{{Pharmacology-stub}}