Tissuemed
{{Short description|British medical device manufacturer}}
{{Multiple issues|
{{Orphan|date=September 2023}}
{{Notability|Companies|date=December 2013}}
}}
{{Use mdy dates|date=December 2013}}
{{Infobox company
|name = Tissuemed Ltd.
|logo = Tissuemed Ltd logo.jpg
|type = Private
|location = Leeds, West Yorkshire, U.K.
|key_people =
|industry = Medical Devices
|products = TissuePatch product family of surgical sealant films
|homepage = [http://www.tissuemed.com/ www.tissuemed.com]
}}
Tissuemed is a medical device developer and manufacturer based in Leeds, UK.
The company was founded in 1985 and developed the first tissue heart valve (derived from pigs) to receive regulatory approval (CE mark) in Europe. This business was divested in 1999,AorTech buys TissueMed's heart valve division. Elservier Business Intelligence, 1999. http://www.elsevierbi.com/deals/199910268 and the heart values are currently sold by Vascutek, a Terumo company, under the Aspire brand.{{cite journal|last=Kumar|first=P|author2=Athanasiou T |author3=Mussa S |author4=Wood AJ. |title=Ten year experience with Aspire (Tissuemed) porcine bioprosthesis: single centre experience.|journal=Cardiovascular Surgery|year=2003|volume=11|issue=2|pages=131–7|pmid=12664048|doi=10.1016/s0967-2109(03)00011-5}}{{cite journal|last=Goldsmith|first=IR|author2=Spyt TJ |author3=Boehm M |author4=Kendall S |author5=Rosin MD. |title=Midterm evaluation of the Tissuemed (Aspire) porcine bioprosthesis: 493 patients, 506 bioprostheses.|journal=The Annals of Thoracic Surgery|year=2001|volume=71|issue=5|pages=1471–6|pmid=11383785|doi=10.1016/s0003-4975(01)02397-9 }} Thereafter, Tissuemed focused on the development of innovative tissue adhesives for internal surgical use, including a light activated tissue sealant to prevent blood loss during vascular anastomosis, the TissueBond system.{{cite journal|last=Birch|first=JF|author2=Mandley DJ |author3=Williams SL |author4=Worrall DR |author5=Trotter PJ |author6=Wilkinson F |author7=Bell PR. |title=Methylene blue based protein solder for vascular anastomoses: an in vitro burst pressure study.|journal=Lasers in Surgery and Medicine|year=2000|volume=26|issue=3|pages=323–9|doi=10.1002/(sici)1096-9101(2000)26:3<323::aid-lsm11>3.0.co;2-r|pmid=10738296 |s2cid=35428707 }}{{cite patent| country = US| number = 6,239,190| status = patent
| title = Enhancement of activation for biological tissue adhesives, bonding agents and sealants using "color change" chromophores| pubdate = 2001|assign1 = Tissuemed Ltd}}
More recently in 2007, Tissuemed launched TissuePatch, a range of surgical sealant films for the prevention of leaks during surgery, including thoracic, general and neurosurgery.{{cite journal|last=Ferroli|first=P|author2=Acerbi, F |author3=Broggi, M |author4=Schiariti, M |author5=Albanese, E |author6=Tringali, G |author7=Franzini, A |author8= Broggi, G |title=A novel impermeable adhesive membrane to reinforce dural closure: a preliminary retrospective study on 119 consecutive high-risk patients.|journal=World Neurosurgery|date=Mar–Apr 2013|volume=79|issue=3–4|pages=551–7|pmid=22120260|doi=10.1016/j.wneu.2011.09.022}}Schiariti M, Acerbi F, Broggi M, Tringali G, Raggi A, Broggi G, Ferroli P. Two alternative dural sealing techniques in posterior fossa surgery: (Polylactide-co-glycolide) self-adhesive resorbable membrane versus polyethylene glycol hydrogel. Surg Neurol Int. 2014 Dec 3;5:171. doi: 10.4103/2152-7806.146154.
These products incorporate a unique synthetic bioadhesive that forms a covalent bond with tissue proteins, enabling adhesion to internal organs and achieving a sealing effect. In June 2016, Tissuemed won approval from China's FDA for its TissuePatch surgical sealant.{{Cite web|url=http://www.massdevice.com/tissuemed-wins-chinas-ok-for-tissuepatch-surgical-sealant/|title=Tissuemed wins China's OK for TissuePatch surgical sealant – MassDevice|website=www.massdevice.com|date=June 2016 |language=en-US|access-date=2017-10-16}}
The company was acquired by Becton Dickinson in 2021.{{cite news |last1=Wright |first1=Greg |title=Leeds based medical device manufacturer Tissuemed is acquired by US-based Becton Dickinson |url=https://www.yorkshirepost.co.uk/business/leeds-based-tissuemed-acquired-by-becton-dickinson-3493534 |access-date=25 August 2022 |work=Yorkshire Post |date=14 December 2021}}