Toxoplasma lactate dehydrogenase 1 regulatory UTR

{{Infobox rfam

| Name = LDH1 5′UTR

| image = RF02697.svg

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| caption = Predicted secondary structure and sequence conservation of LDH1 5′UTR

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| Rfam = RF02697

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| Tax_domain = Bacteria

| GO = {{GO|0045182}}

| SO = {{SO|0005836}},{{SO|0000204}}

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In Toxoplasma gondii the translational repression of lactate dehydrogenase 1 (LDH1) was discovered to be mediated through its 5′UTR. A small nucleotide regulatory RNA hairpin was shown to be essential for the repression. It is possible that this hairpin may act as the nucleation site for the binding of a trans-acting factor(s) that allow for the translational repression.{{cite journal | vauthors = Holmes M, Itaas V, Ananvoranich S | title = Sustained translational repression of lactate dehydrogenase 1 in Toxoplasma gondii bradyzoites is conferred by a small regulatory RNA hairpin | journal = The FEBS Journal | volume = 281 | issue = 22 | pages = 5077–5091 | date = November 2014 | pmid = 25223457 | doi = 10.1111/febs.13048 | s2cid = 45643970 | doi-access = free }}