Tramazoline

{{Short description|Chemical used as a nasal decongestant}}

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{{Expand German|Tramazolin|date=December 2017}}

{{Drugbox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 457287903

| IUPAC_name = N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine

| image = Tramazoline.svg

| width = 175

| tradename =

| Drugs.com = {{drugs.com|international|tramazoline}}

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| CAS_number_Ref = {{cascite|changed|??}}

| CAS_number = 1082-57-1

| ATC_prefix = R01

| ATC_suffix = AA09

| PubChem = 5524

| DrugBank_Ref = {{drugbankcite|correct|drugbank}}

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| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = SLE31693IV

| ChEMBL_Ref = {{ebicite|changed|EBI}}

| ChEMBL = 32573

| KEGG_Ref = {{keggcite|changed|kegg}}

| KEGG = D08624

| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}

| ChemSpiderID = 5323

| C=13 | H=17 | N=3

}}

Tramazoline is a chemical that is used in the form of tramazoline hydrochloride in nasal decongestant preparations.{{cite web| author= |title=Spray-Tish Consumer Information|url=http://www.mydr.com.au/medicines/cmis/spray-tish-nasal-spray |website= MyDr.com.au|accessdate=16 April 2011}} It is an α-adrenergic receptor agonist that inhibits secretion of nasal mucus.

It was patented in 1961 and came into medical use in 1962.{{cite book | vauthors = Fischer J, Ganellin CR |title=Analogue-based Drug Discovery |date=2006 |publisher=John Wiley & Sons |isbn=978-3-527-60749-5 |page=552 |url=https://books.google.com/books?id=FjKfqkaKkAAC&pg=PA552 |language= en}}

Brand names

  • Australia
  • Spray-Tish{{cite web|title= Consumer medicine information: Spray-Tish| url= https://www.nps.org.au/medicine-finder/spray-tish-nasal-spray |work= nps.org.au| publisher= NPS MedicineWise |date= 8 September 2017|accessdate=September 13, 2021 }}
  • Rhinaspray
  • Austria
  • Rhinorix
  • Belgium
  • Rhinospray
  • Bulgaria
  • Muconasal Plus
  • Czech Republic
  • Muconasal Plus
  • Germany
  • Biciron
  • Ellatun
  • Rhinospray
  • Hungary
  • Rhinospray Plus
  • Italy
  • Rinogutt
  • Fexallegra nasale (Tramazoline + Chlorpheniramine, 1 mg/mL + 3.55 mg/mL)
  • The Netherlands
  • Bisolnasal
  • Portugal
  • Rhinospray
  • Romania
  • Muconasal Plus (older)
  • Muconasal (newer)
  • Russia
  • Adrianol (tramazoline + phenylephrine)
  • Lasolvan Rhino
  • Spain
  • Rhinospray
  • Slovakia
  • Muconasal Plus
  • Ukraine
  • Lasorin

References

{{reflist}}

{{Nasal preparations}}

Category:Imidazolines

Category:Tetralins

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