Tryptophan dimethylallyltransferase

{{Short description|Class of enzymes}}

{{infobox enzyme

| Name = tryptophan dimethylallyltransferase

| EC_number = 2.5.1.34

| CAS_number = 55127-01-0

| GO_code = 0050364

| image =

| width =

| caption =

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In enzymology, a tryptophan dimethylallyltransferase ({{EC number|2.5.1.34}}) is an enzyme that catalyzes the chemical reaction

:dimethylallyl diphosphate + L-tryptophan \rightleftharpoons diphosphate + 4-(3-methylbut-2-enyl)-L-tryptophan

Thus, the two substrates of this enzyme are dimethylallyl diphosphate and L-tryptophan, whereas its two products are diphosphate and 4-(3-methylbut-2-enyl)-L-tryptophan.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is {{chem name|dimethylallyl-diphosphate:L-tryptophan dimethylallyltransferase}}. Other names in common use include {{chem name|dimethylallylpyrophosphate:L-tryptophan dimethylallyltransferase}}, {{chem name|dimethylallyltryptophan synthetase}}, {{chem name|dimethylallylpyrophosphate:tryptophan dimethylallyl transferase}}, DMAT synthetase, and {{chem name|4-(gamma,gamma-dimethylallyl)tryptophan synthase}}.

References

{{reflist|1}}

  • {{cite journal | vauthors = Lee SL, Floss HG, Heinstein P | date = 1976 | title = Purification and properties of dimethylallylpyrophosphate:tryptopharm dimethylallyl transferase, the first enzyme of ergot alkaloid biosynthesis in Claviceps. sp. SD 58 | journal = Arch. Biochem. Biophys. | volume = 177 | pages = 84–94 | pmid = 999297 | doi = 10.1016/0003-9861(76)90418-5 | issue = 1 }}

{{Alkyl and aryl transferases}}

{{Enzymes}}

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Category:EC 2.5.1

Category:Enzymes of unknown structure

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