Tuomas Knowles
{{Infobox scientist
| name = Tuomas Knowles
| native_name =
| native_name_lang =
| image =
| image_size =
| alt =
| caption =
| birth_name =
| birth_date =
| birth_place =
| death_date =
| death_place =
| resting_place =
| resting_place_coordinates =
| other_names =
| siglum =
| citizenship =
| nationality = British, Finnish
| fields = Biophysics, Chemistry, Physical Chemistry{{Cite web|url=https://scholar.google.co.uk/citations?user=vm5ZZlMAAAAJ&hl=en|title=Tuomas Knowles|website=scholar.google.co.uk}}
| workplaces = University of Cambridge
| patrons =
| alma_mater = ETH Zurich, University of Cambridge, University of Geneva
| thesis_title =
| thesis_url =
| thesis_year =
| doctoral_advisor = Sir Mark Welland
| academic_advisors = Sir Chris Dobson
| doctoral_students =
| notable_students =
| known_for = Protein biophysics
| author_abbrev_bot =
| author_abbrev_zoo =
| influences =
| influenced =
| awards = Corday–Morgan Prize from the Royal Society of Chemistry, Raymond and Beverly Sackler International Prize in Biophysics, Harrison-Meldola Memorial Prize from the Royal Society of Chemistry, Rita and John Cornforth Award, Royal Society of Chemistry, 2019
| signature =
| signature_alt =
| website =
| footnotes =
| spouse =
| children =
| partner =
}}
Tuomas Knowles is a British scientist and Professor of Physical Chemistry and Biophysics at the Department of Chemistry{{Cite web|url=https://www-knowles.ch.cam.ac.uk/directory/tpjk|title=Tuomas Knowles — Knowles Lab|website=www-knowles.ch.cam.ac.uk|date=9 June 2016 }} and at the Cavendish Laboratory at the University of Cambridge.{{Cite web|url=https://www.phy.cam.ac.uk/directory/professor-tuomas-knowles|title=Professor Tuomas Knowles — Department of Physics|website=www.phy.cam.ac.uk|date=10 May 2019 }} He is the co-director of the Cambridge Centre for Misfolding Diseases{{Cite web|url=https://www.cmd.ch.cam.ac.uk/|title=Index | Centre for Misfolding Diseases|website=www.cmd.ch.cam.ac.uk}} and a Fellow of St John's College, Cambridge.St John%27s College, Cambridge{{Circular reference|date=March 2021}} Prof. Knowles is a co-founder of four biotechnology companies: Fluidic Analytics, Wren Therapeutics, Xampla and Transition Bio. He was also the Cambridge Enterprise Academic Entrepreneur of the year in 2019.{{Cite web|url=https://www.ifm.eng.cam.ac.uk/news/helping-to-celebrate-regional-entrepreneurship/|title=IfM News and Features|website=www.ifm.eng.cam.ac.uk}}
Education
Tuomas Knowles studied Biology at the University of Geneva and Physics at the Swiss Federal Institute of Technology in Zurich and at the University of Cambridge. He holds a Ph.D. in Physics from the University of Cambridge and a master's degree in Physics from the Swiss Federal Institute of Technology Zurich. He was a visiting scholar at Harvard University{{Cite web|url=https://weitzlab.seas.harvard.edu/people/tuomas-knowles|title=Tuomas Knowles|website=weitzlab.seas.harvard.edu}} and Weston Visiting Professor at the Weizmann Institute of Science in Israel.
Research
The research of Tuomas Knowles focuses on understanding protein behavior in health and disease. Knowles is known for his work on protein aggregation and for describing the kinetics of this process and the underlying molecular mechanisms. He discovered the first integrated rate law for amyloid formation{{cite journal | vauthors = Knowles TP, Waudby CA, Devlin GL, Cohen SI, Aguzzi A, Vendruscolo M, Terentjev EM, Welland ME, Dobson CM | s2cid = 6267152 | display-authors = 6 | title = An analytical solution to the kinetics of breakable filament assembly | journal = Science | volume = 326 | issue = 5959 | pages = 1533–7 | date = December 2009 | pmid = 20007899 | doi = 10.1126/science.1178250 | bibcode = 2009Sci...326.1533K }} which has allowed the mechanisms of this process to be elucidated by researchers worldwide and together with collaborators he has made software available to the research community for kinetic analysis of protein aggregation. He has published over 300 papers, has an H-index of 70 and has been named Highly Cited Researcher by the Web of Science.{{Cite web|url=https://www.ch.cam.ac.uk/news/five-professors-named-2019-highly-cited-researchers|title=Five Professors named as 2019 Highly Cited Researchers | Yusuf Hamied Department of Chemistry|website=www.ch.cam.ac.uk}}
Awards and honors
- Corday-Morgan Prize from the Royal Society of Chemistry (awarded in 2017).{{Cite web|url=https://www.rsc.org/news-events/articles/2017/may/awards-and-prizes-2017/|title=Prizes and awards 2017|website=Royal Society of Chemistry|date=9 May 2017 }}
- Raymond and Beverly Sackler International Prize in Biophysics (awarded in 2017).{{Cite web|url=https://english.tau.ac.il/sackler_prize_in_biophysics_past_laureates|title=Past Laureates of the Raymond and Beverly Sackler International Prize in Biophysics|date=September 5, 2012|website=Tel Aviv University}}
- Harrison-Meldola Memorial Prize from the Royal Society of Chemistry{{Cite web|url=https://www.rsc.org/prizes-funding/prizes/find-a-prize/harrison-meldola-memorial-prizes/previous-winners/|title=Previous winners|website=Royal Society of Chemistry}}
- Young Investigator Award and Medal, British Biophysical Society
- Young Scientist Prize in Biological Physics, International Union of Pure and Applied Physics
- Rita and John Cornforth Award, The Royal Society of Chemistry
References
{{reflist}}
{{authority control}}
{{DEFAULTSORT:Knowles, Tuomas}}
Category:Alumni of the University of Cambridge
Category:University of Geneva alumni
Category:Scientists of the Cavendish Laboratory
Category:Professors of the University of Cambridge