U.S. Route 50

{{lengths table}}

|-

|CA

|{{convert|109|mi|km|disp=table}}

|-

|NV

|{{convert|409|mi|km|disp=table}}

|-

|UT

|{{convert|335|mi|km|disp=table}}

|-

|CO

|{{convert|468|mi|km|disp=table}}

|-

|KS

|{{convert|448|mi|km|disp=table}}

|-

|MO

|{{convert|264|mi|km|disp=table}}

|-

|IL

|{{convert|166|mi|km|disp=table}}

|-

|IN

|{{convert|171|mi|km|disp=table}}

|-

|OH

|{{convert|209|mi|km|disp=table}}

|-

|WV

|{{convert|196|mi|km|disp=table}}

|-

|VA

|{{convert|86|mi|km|disp=table}}

|-

|DC

|{{convert|8|mi|km|disp=table}}

|-

|MD

|{{convert|150|mi|km|disp=table}}

|-

|Total

|{{convert|3,019|mi|km|disp=table}}

|}

File:Mileage Sign At West End of US 50.jpg at the western terminus of US 50]]

{{main|U.S. Route 50 in California|U.S. Route 50 in Nevada|U.S. Route 50 in Utah|U.S. Route 50 in Colorado}}

Image:Us route 50 nevada.jpg

US 50 begins as a major freeway at its junction with Interstate 80 in West Sacramento and continues into Sacramento. The portion of US 50 west of and including its interchange with California's State Highway 99 in Sacramento is also designated, but not signed as, Interstate 305. The signage along this portion of the highway indicates Business Loop I-80 and a portion of the way (2 miles/3.33 km) as California State Highway 99. From Sacramento, the highway heads eastward as the William Alexander Leidesdorff, Jr. Memorial Highway, continuing as a freeway to the Gold Country foothills, then following the American River up the Sierra Nevada as a conventional highway, until cresting the Sierras at Echo Summit and descending to Lake Tahoe, where the highway enters Nevada. In Nevada, the highway crosses a series of north–south running mountain ranges that break up the Nevada desert which are called Basin and Range. East of Carson City, the road enters the heart of the Great Basin, passing by few communities and minimal services, giving it the name "Loneliest Road in America" until reaching Utah.{{cite web |author = Nevada Commission on Tourism |url = http://files.travelnevada.com/guides/11300/11297/original-hwy50-issu.pdf |title = The Official Hwy 50 Survival Guide: The Loneliest Road in America |access-date = May 10, 2016 |publisher = Nevada Commission on Tourism |archive-url = https://web.archive.org/web/20160123053802/http://files.travelnevada.com/guides/11300/11297/original-hwy50-issu.pdf |archive-date = January 23, 2016 |url-status = dead |df = mdy-all }}

In Utah, US 50 also passes through desolate, remote areas with few inhabitants. After crossing the Confusion Range via Kings Canyon and the House Range, the road traverses the north shore of the endorheic Sevier Lake. In Holden, US 50 shortly overlaps Interstate 15 to cross the Pavant Range. The road begins a much longer overlap with Interstate 70 in Salina crossing the Wasatch Plateau and San Rafael Swell into Colorado. US 50 leaves I-70 upon entering the state and heads southeast through Grand Junction and into the southern part of Colorado. Once there, the road climbs to its highest elevation of {{convert|11312|ft}}{{cite book |title=Cycling Colorado's Mountain Passes |last=Magsamen |first=Kurt |year=2002 |publisher=Fulcrum Publishing |isbn=1-55591-294-X |page=152 |url=https://books.google.com/books?id=qdWnRHuE5sEC&q=US+Highway+50+11312&pg=PA152 |access-date=2009-08-01}} over the Rocky Mountains and in Monarch Pass where it crosses the Continental Divide. After descending from the Rockies, US 50 passes by Royal Gorge near Cañon City and serves Pueblo. The route then joins U.S. Route 400 in Granada and follows the Arkansas River into Kansas.{{google maps |title=National Map of U.S. Route 50 |url = https://maps.google.com/maps?f=d&source=s_d&saddr=I-80+Bus+E&daddr=US-50+E+to:US-50+to:US-50+to:US-50+to:US-50+to:US-50+to:US-50+to:I-44+E+to:S+Lindbergh+Blvd%2FUS-50%2FUS-61%2FUS-67+to:S+Lindbergh+Blvd%2FUS-50%2FUS-61%2FUS-67+to:38.508147,-90.32989+to:I-255+N+to:New+Route+50%2FUS-50+to:US-50+to:US-50+to:Unknown+road+to:US-50%2FWooster+Pike+to:W+Main+St%2FOH-41%2FUS-50+to:John+Mosby+Hwy%2FUS-50+to:Fairfax+Blvd%2FUS-29%2FUS-50+to:Arlington+Blvd%2FUS-50+to:Arlington+Blvd%2FUS-50+to:Constitution+Ave+NW%2FUS-50+to:N+Division+St%2FMD-528&geocode=FaCbTAIdYPbA-A%3BFQzlTQId1yfK-A%3BFUglWAIdR6v4-A%3BFRLqWwIdYt79-A%3BFVRgSQIdaHOy-Q%3BFXh6QAIdWM8J-g%3BFcYrQwId4goZ-g%3BFVCwTQIdgkZ5-g%3BFUDrSgIdCKSV-g%3BFWofTAIdwJmc-g%3BFRqYSwIdhqqd-g%3B%3BFQgeSwId9Pme-g%3BFQBITQIdKn2p-g%3BFdoxUQIdNFLZ-g%3BFSgcVQIdOHXz-g%3BFfKYVAIdyk72-g%3BFRZHVQId2Ff4-g%3BFQiQVgIdOF8J-w%3BFUAgUgIdTt1g-w%3BFbD8UAIdqpZk-w%3BFbQRUQIdEDRm-w%3BFUFrUQIduuVn-w%3BFRJyUQIdEE9o-w%3BFcLkSAIdbUaG-w&hl=en&mra=dme&mrcr=1&mrsp=11&sz=15&via=1,2,3,4,6,7,8,9,10,11,12,13,14,15,17,18,19,20,21,22,23&sll=38.506115,-90.329354&sspn=0.014541,0.027595&ie=UTF8&ll=36.137875,-98.964844&spn=15.34217,45&z=5 |access-date = July 31, 2009 }}

{{main|U.S. Route 50 in Kansas|U.S. Route 50 in Missouri|U.S. Route 50 in Illinois|U.S. Route 50 in Indiana|U.S. Route 50 in Ohio}}

Image:Jefferson Barracks Bridge 1993 flood cropped.jpg over the Mississippi River]]

Upon entering Kansas, US 50, concurrent with US 400, runs along the Arkansas River to Dodge City where US 50 splits from US 400 and takes a more northerly course. US 50 continues to traverse the farmlands and small towns of the Great Plains mostly as a straight two-lane road until Emporia where it joins Interstate 35 and splits onto Interstate 435 to bypass the center of the Kansas City Area. In Missouri, US 50 leaves I-435 for Interstate 470 splitting at Lee's Summit. US 50 runs as a four-lane divided highway across the Western Plain to Sedalia where it continues as a two-lane road until reaching California, MO about 20 miles west of Jefferson City. The road continues as a four-lane divided highway into Jefferson City where it joins US 63 just south of the Missouri River Bridge. It continues 12 miles east of Jefferson City to the Osage River where US 63 splits off to the south. It then continues as a two-lane road as it traverses the northern sections of the Ozark Highlands east to Union where it begins an overlap with Interstate 44 which goes through Pacific. The routes separate in Sunset Hills where US 50 migrates southeast bypassing St Louis by joining Interstate 255 to cross Mississippi River into Illinois.

In that state, US 50 switches to Interstate 64 before splitting onto its own alignment in eastern O'Fallon. It heads east through Trenton, Breese, Carlyle crossing the Kaskaskia River, Salem, Flora and Lawrenceville to the Wabash River along a corridor between Interstates 64 and 70. US 50 enters Indiana at the Wabash River, bypassing Vincennes and Washington and passing through Bedford, Seymour, and Versailles. It meets the Ohio River at Aurora, and soon crosses into Ohio, running through downtown Cincinnati via Fort Washington Way (Interstate 71). The route crosses southern Ohio via Hillsboro, Chillicothe, and Athens, joining the four-lane divided Corridor D (State Route 32) west of Athens. It meets the Ohio River around Belpre, and crosses the newer Blennerhassett Island Bridge (previously crossing the Parkersburg-Belpre Bridge) into greater Parkersburg, West Virginia.

File:Saddle-mtn.jpg atop the Allegheny Front along US 50 in West Virginia]]

Image:DC us50 shield.jpg

File:Chesapeake Bay Bridge 2012.jpg, carrying US 50/US 301 over the bay]]

File:US 50 WB past MD 528.jpeg

{{main|U.S. Route 50 in West Virginia|U.S. Route 50 in Virginia|U.S. Route 50 in the District of Columbia|U.S. Route 50 in Maryland}}

The portion of US 50 from Parkersburg, West Virginia to Winchester, Virginia follows the historic Northwestern Turnpike, which crosses the southern tip of Garrett County, Maryland. From Parkersburg to Interstate 79 east of Clarksburg, US 50 has been upgraded as part of the four-lane divided Corridor D. US 50 is a curving two-lane mountain road, east of Clarksburg through Grafton, a bit of Maryland, and Romney to Winchester. This portion of the road is so curvy that locals claim "you can meet yourself coming." The land flattens out after the route crosses the Blue Ridge Mountain east of Winchester, and it follows the old Little River Turnpike from Aldie to Fairfax City and the newer Arlington Boulevard to Rosslyn, where it crosses the Washington, D.C. line on the west shore of the Potomac River and joins Interstate 66 on the Theodore Roosevelt Bridge.

Within the District, US 50 immediately exits the freeway onto Constitution Avenue along the north side of the National Mall and south of the White House. After turning north on 6th Street Northwest, it exits the city to the northeast on New York Avenue. Upon crossing into Maryland, it passes the south end of the Baltimore-Washington Parkway and becomes the John Hanson Highway, a freeway to Annapolis. The portion of this highway east of the Capital Beltway (I-95/I-495) is also designated, but not signed as, Interstate 595, and U.S. Route 301 joins from the south at Bowie. The freeway continues beyond Annapolis as the Blue Star Memorial Highway which crosses the Chesapeake Bay on the Chesapeake Bay Bridge and continues to Queenstown. There the Blue Star Memorial Highway continues northeast as US 301, while US 50 turns south, passing through Easton to Cambridge, and then east through Salisbury to Ocean City on the four-lane divided Ocean Gateway. US 50 ends near the Atlantic Ocean shore at Baltimore Avenue (Maryland Route 378 northbound); its westbound beginning is one block to the west, at Philadelphia Avenue (Maryland Route 528 southbound).

Image:US50LoneliestRoadInAmerica.jpg]]

{{Hatnote|For more details, see the state-specific articles linked in the route description above.}}

Before the creation of the Interstate Highway System after World War II, US 50 was a major east–west route. Numbered highways in the United States follow a pattern of odd numbers for north–south routes and even numbers for east–west routes, hence the designation of "50" for this route. In the preliminary report, approved by the Joint Board on Interstate Highways in late 1925, US 50 ran from Wadsworth, Nevada to Annapolis, Maryland, passing through Pueblo, Colorado; Kansas City, Missouri; Tipton, Missouri; St. Louis, Missouri; Cincinnati, Ohio, and Washington, D.C.{{cite book |type= Report |author = Joint Board on Interstate Highways |year = 1925 |chapter = Appendix VI: Descriptions of the Interstate Routes Selected, with Numbers Assigned |chapter-url = https://en.wikisource.org/wiki/Report_of_Joint_Board_on_Interstate_Highways_October_30,_1925#53 |title = Report of Joint Board on Interstate Highways, October 30, 1925, Approved by the Secretary of Agriculture, November 18, 1925 |location= Washington, DC |publisher= United States Department of Agriculture |page = 53 |id= {{OCLC|733875457|55123355|71026428}} |via = Wikisource |access-date = November 14, 2017 }} The route did not directly replace any auto trail, instead combining portions of many into one continuous route. It followed the historic Northwestern Turnpike across West Virginia, and portions of other historic roads. Major auto trails followed, including the Midland Trail in part of Indiana, Illinois, Missouri, and parts of Utah and Colorado. The National Old Trails Road (Old Santa Fe Trail) was designated in Kansas and eastern Colorado, and the Lincoln Highway was constructed in Nevada.{{cite map |publisher=Rand McNally |title=United States Road Atlas |url=http://www.broermapsonline.org/members/NorthAmerica/UnitedStates/ |year=1926 |access-date=2009-08-03}} In most states that had numbered their state highways, US 50 followed only one or two numbers across the state.The following routes were used, mostly shown on the 1926 Rand McNally:

• Nevada: 2
• Utah: 8 (in the east half of the state; the west half was unnumbered)
• Colorado: 6
• Kansas: state highways were not numbered prior to the U.S. Highway system
• Missouri: 12, shown on Missouri State Highway Commission, [http://www.cosmos-monitor.com/mo/hist/maps/etc/map1922-backlin.html Route Map Showing Designated Routes and Numbers], Approved September 19, 1922
• Illinois: 12
• Indiana: 4 and 5; by 1926, a short piece was 41, but this was originally part of 5, shown on the description of the [http://www.libraries.iub.edu/index.php?pageId=2980 1917 Indiana State Highway Map] {{Webarchive|url=https://web.archive.org/web/20110520185627/http://www.libraries.iub.edu/index.php?pageId=2980 |date=May 20, 2011 }} at the Indiana University Bloomington Libraries
• Ohio: mostly 26; it had been Main Market Route V in the 1910s, shown on 1914, 1915, and 1917 [http://www.dot.state.oh.us/Divisions/TransSysDev/Innovation/Prod_Services/TransMap/Pages/default.aspx Ohio Transportation Maps]
• West Virginia: 1
• Virginia: 36; it had been 6 until the 1923 renumbering, shown in the [http://www.vahighways.com/route-log/VDOT%20logs/log1918.htm route descriptions as defined by the General Assembly] on January 31, 1918
• Maryland: state highways were not numbered prior to the U.S. Highway system

One major controversy related to the preliminary route of US 50. The through route had been assigned to the Old Santa Fe Trail, while the spur U.S. Route 250 followed the competing New Santa Fe Trail to the south. As a compromise, the Joint Board on Interstate Highways approved a split configuration—U.S. Route 50N and U.S. Route 50S—in January.{{cite web |first = Richard F. |last = Weingroff |url = https://www.fhwa.dot.gov/infrastructure/numbers.cfm |title = From Names to Numbers: The Origins of the U.S. Numbered Highway System |publisher = Federal Highway Administration }} Another problem was in western Utah, where no improved road existed for US 50 to use. The final numbering plan, approved in November 1926, left a gap in US 50 between Ely, Nevada and Thistle, Utah. Finally, rather than ending US 50 at Wadsworth, where the Lincoln and Victory Highways merged, it was sent over the Lincoln Highway's Pioneer Branch, past the south side of Lake Tahoe, to Sacramento, California.{{cite map |author1= Bureau of Public Roads |author2= American Association of State Highway Officials |date= November 11, 1926 |title= United States System of Highways Adopted for Uniform Marking by the American Association of State Highway Officials |url= https://commons.wikimedia.org/wiki/File:United_States_System_of_Highways_Adopted_for_Uniform_Marking_by_the_American_Association_of_State_Highway_Officials.jpg |scale= 1:7,000,000 |location= Washington, DC |publisher= United States Geological Survey |oclc= 32889555 |access-date= November 7, 2013 |via= Wikimedia Commons |name-list-style= amp}}{{cite book |chapter = United States Numbered Highways |title = American Highways |publisher = American Association of State Highway Officials |date = April 1927 }}

The gap in Utah was soon bypassed by taking US 50 to the north, crossing the Great Salt Lake Desert with U.S. Route 40 to Salt Lake City, and using long portions of U.S. Route 93 in Nevada and U.S. Route 89 in Utah.Nevada Department of Highways, [http://contentdm.library.unr.edu/u?/hmaps,459 Road Map] {{Webarchive|url=https://web.archive.org/web/20150613102542/http://contentdm.library.unr.edu/u?%2Fhmaps%2C459 |date=June 13, 2015 }}, 1932 U.S. Route 6 was marked along the direct, but still partially unimproved, route in 1937; it was finally paved in 1952,{{cite web |first = Richard F. |last = Weingroff |url = https://www.fhwa.dot.gov/infrastructure/us6.cfm |title = US 6: The Grand Army of the Republic Highway |publisher = Federal Highway Administration }} and US 50 was moved to it within a few years.{{cite map |publisher=Nevada Department of Highways |title=Official Highway Map of Nevada |url=http://www.nevadadot.com/traveler/maps/historical/pdfs/1954HwyMapDuplexWeb.pdf |year=1954 |cartography=Rand McNally & Company|access-date=2009-08-03 }} Another straightening was made in 1976, when US 50 in central Utah was moved south onto the new extension of Interstate 70 at the request of the National Highway 50 Federation,Senate Committee on Public Works, [https://books.google.com/books?id=OjjeVS7e2VQC&q=%22State+Highway+63+from+Scipio Designating Highway US 50 as Part of the Interstate System, Nevada], 1970, p. 68: recommends that the road between Delta and Salina receive a single number{{cite web |title=SR-50 |url=http://www.udot.utah.gov/main/uconowner.gf?n=200609140952271 |pages=4–12 |publisher=Utah Department of Transportation |access-date=2 August 2009 |archive-date=October 19, 2007 |archive-url=https://web.archive.org/web/20071019011433/https://www.udot.utah.gov/main/uconowner.gf?n=200609140952271 |url-status=dead }} a group dedicated to promoting US 50.{{cite news |work = Rocky Mountain News |title = Highway to Heaven |date = November 1, 1992 }} Among other things, the group has unsuccessfully pushed for an extension of Interstate 70 west along US 50 to California.{{cite web |publisher = Federal Highway Administration |url = https://www.fhwa.dot.gov/infrastructure/covefort.cfm |title = Ask the Rambler: Why Does I-70 End in Cove Fort, Utah? }}

The north–south split in Kansas was eliminated in the late 1950s, with the south route—which was to be US 250—becoming part of US 50, and most of US 50N becoming part of a new U.S. Route 56.[http://www.ksdot.org/burtransplan/maps/HistoricStateMaps.asp KDOT Historic State Maps], 1956 and 1957–1958 Another split was located between Athens, Ohio and Ellenboro, West Virginia from the late 1920s to the mid-1930s, when US 50 went back to its original southern route; that U.S. Route 50N is now Ohio State Route 550 and part of West Virginia Route 16.{{cite web |url = http://www.dot.state.oh.us/techservsite/availpro/GIS_Mapping/mrsid/default.htm |title = Ohio Transportation Maps |archive-url = https://web.archive.org/web/20070625053747/http://www.dot.state.oh.us/techservsite/availpro/GIS_Mapping/mrsid/default.htm |archive-date=2007-06-25 |date= 1928–1935 }}

At its west end, US 50 was extended south from Sacramento along U.S. Route 99 to Stockton and west to the San Francisco Bay Area, replacing U.S. Route 48, by the early 1930s.{{cite map |author = Rand McNally & Company |author-link = Rand McNally & Company |url = http://members.cox.net/mkpl2/hist/hist.html |year = 1933 |title = California |archive-url=https://web.archive.org/web/20111202003424/http://members.cox.net/mkpl2/hist/hist.html |archive-date=2011-12-02 }} US 50 was officially cut back to Sacramento in the 1964 renumbering, replaced by Interstate 580,California Streets and Highways Code, 1963: "Route 50 is from Route 80 in Sacramento to the Nevada state line near Lake Tahoe via Placerville. (Repealed and added by Stats. 1963, Ch. 385.)" but remained on maps and signs for several more years.{{cite map |author = Thomas Guide |author-link = Thomas Guide |url = http://www.pcpages.com/sanfrancisco/map3.htm|archive-url = https://web.archive.org/web/20040605163248/http://www.pcpages.com/sanfrancisco/map3.htm |archive-date = 2004-06-05 |title = San Francisco |year = 1967 }}{{cite news |date=July 19, 1967 |title=Highway Projects Speed Along |page=C1 |work=Modesto Bee and News-Herald |url=https://www.newspapers.com/clip/121025091/highway-projects-speed-along/ |via=Newspapers.com |accessdate=March 16, 2023 |quote=Route 205, which will be the North Tracy Bypass linking Route 580 (the present Route 50) to Interstate 5 }} US 50 was extended east from Annapolis to Ocean City, Maryland in 1949, three years prior to the opening of the Chesapeake Bay Bridge in 1952; this extension replaced Maryland Route 404 between Annapolis and Wye Mills and U.S. Route 213 between Wye Mills and Ocean City. Prior to the bridge opening, US 50 used a ferry across the Chesapeake Bay between Sandy Point and Matapeake and followed present-day Maryland Route 8 between Matapeake and Stevensville before continuing east.{{Maryland road map|year=1949}}

;California

: {{jct|country=USA|I|80}} in West Sacramento

: {{jct|country=USA|I|5}} in Sacramento

;Nevada

: {{jct|country=USA|I|580|dab1=Nevada|US|395}} in Carson City. The highways travel concurrently through the city.

: {{jct|country=USA|US|95}} in Fallon. The highways travel concurrently through the city.

: {{jct|country=USA|US|93}} in Ely. The highways travel concurrently to Majors Place.

: {{jct|country=USA|US|6}} in Ely. The highways travel concurrently to Delta, Utah.

;Utah

: {{jct|country=USA|I|15}} north-northeast of Holden. The highways travel concurrently to Scipio.

: {{jct|country=USA|US|89}} in Salina. The highways travel concurrently through the city.

: {{jct|country=USA|I|70|US|89}} in Salina. I-70/US 50 travels concurrently to south-southwest of Mack, Colorado.

: {{jct|country=USA|US|6|US|191}} west of Green River. US 6/US 50 travels concurrently to Grand Junction, Colorado. US 50/US 191 travels concurrently to west-southwest of Thompson Springs.

;Colorado

: {{jct|country=USA|I|70}} in Grand Junction

: {{jct|country=USA|US|550}} in Montrose

: {{jct|country=USA|US|285}} in Poncha Springs. The highways travel concurrently through the town.

: {{jct|country=USA|I|25|US|85|US|87}} in Pueblo. The highways travel concurrently through the city.

: {{jct|country=USA|US|350}} in La Junta

: {{jct|country=USA|US|287}} south of Wiley. The highways travel concurrently to Lamar.

: {{jct|country=USA|US|287|US|385}} in Lamar. US 50/US 385 travels concurrently to Granada.

: {{jct|country=USA|US|385|US|400}} in Granada. US 50/US 400 travels concurrently to west of Dodge City, Kansas.

;Kansas

: {{jct|country=USA|US|83}} north-northwest of Garden City. The highways travel concurrently to Garden City.

: {{jct|country=USA|US|56|US|283}} in Dodge City. US 50/US 56 travels concurrently to Kinsley. US 50/US 283 travels concurrently to west-southwest of Wright.

: {{jct|country=USA|US|183}} in Kinsley

: {{jct|country=USA|US|281}} south of St. John

: {{jct|country=USA|I|135|US|81}} in Newton. The highways travel concurrently through the city.

: {{jct|country=USA|US|77}} in Florence.

: {{jct|country=USA|I|35|I|335|dab2=Kansas}} in Emporia

: {{jct|country=USA|I|35}} east of Emporia. The highways travel concurrently to Lenexa.

: {{jct|country=USA|US|75}} south-southeast of Olivet

: {{jct|country=USA|US|59}} in Ottawa. The highways travel concurrently to northeast of Ottawa.

: {{jct|country=USA|US|56}} in Gardner. The highways travel concurrently to Lenexa.

: {{jct|country=USA|US|169}} in Olathe. The highways travel concurrently to Lenexa.

: {{jct|country=USA|I|35|I|435|US|56|US|169}} in Lenexa. I-435/US 50 travels concurrently to Kansas City, Missouri.

: {{jct|country=USA|US|69}} in Overland Park

;Missouri

: {{jct|country=USA|I|49|I|435|I|470|dab3=Missouri|US|71}} in Kansas City. I-470/US 50 travel concurrently to Lee's Summit.

: {{jct|country=USA|US|65}} in Sedalia

: {{jct|country=USA|US|54|US|63}} in Jefferson City. US 50/US 63 travels concurrently to north of Westphalia.

: {{jct|country=USA|I|44}} south-southwest of Villa Ridge. The highways travel concurrently to the Sunset Hills–Kirkwood city line.

: {{jct|country=USA|I|270|dab1=Illinois–Missouri}} in Sunset Hills

: {{jct|country=USA|I|44|US|61|US|67}} on the Sunset Hills–Kirkwood city line. US 50/US 61/US 67 travels concurrently to Mehlville.

: {{jct|country=USA|I|255}} in Mehlville. The highways travel concurrently to Caseyville, Illinois.

;Illinois

: {{jct|country=USA|I|64|I|255}} in Caseyville. I-64/US 50 travels concurrently to O'Fallon.

: {{jct|country=USA|US|51}} in Sandoval. The highways travel concurrently through the village.

: {{jct|country=USA|I|57}} in Salem

: {{jct|country=USA|US|45}} northwest of Flora. The highways travel concurrently to east of Flora.

;Indiana

: {{jct|country=USA|US|41|US|150}} in Vincennes. US 41/US 50 travels concurrently through the city. US 50/US 150 travels concurrently to Shoals.

: {{jct|country=USA|I|69}} east of Washington

: {{jct|country=USA|US|231}} in Loogootee. The highways travel concurrently through the city.

: {{jct|country=USA|I|65}} in Seymour

: {{jct|country=USA|US|31}} in Seymour

: {{jct|country=USA|US|421}} in Versailles. The highways travel concurrently through the town.

: {{jct|country=USA|I|275|dab1=Ohio–Indiana–Kentucky}} in Greendale.

;Ohio

: {{jct|country=USA|US|27|US|42|US|52|US|127}} in Cincinnati

: {{jct|country=USA|I|71|I|75}} in Cincinnati. I-71/US 50 travels concurrently through the city.

: {{jct|country=USA|I|471}} in Cincinnati

: {{jct|country=USA|US|52}} in Cincinnati

: {{jct|country=USA|US|68}} in Fayetteville

: {{jct|country=USA|US|62}} in Hillsboro

: {{jct|country=USA|US|23|US|35}} in Scioto Township. US 23/US 50 travels concurrently through the township. US 35/US 50 travels concurrently to Schrader.

: {{jct|country=USA|US|33}} in Athens. The highways travel concurrently to Athens Township.

;West Virginia

: {{jct|country=USA|I|77}} east of Parkersburg

: {{jct|country=USA|US|19}} in Clarksburg

: {{jct|country=USA|I|79}} in Clarksburg

: {{jct|country=USA|US|250}} west-southwest of Pruntytown. The highways travel concurrently to Pruntytown.

: {{jct|country=USA|US|119}} in Grafton

;Maryland

: {{jct|country=USA|US|219}} in Red House

;West Virginia

: {{jct|country=USA|US|220}} southeast of New Creek. The highways travel concurrently to Junction.

;Virginia

: {{jct|country=USA|US|11|US|17|US|522}} in Winchester. US 11/US 50 travels concurrently through the city. US 17/US 50 travels concurrently to Paris. US 50/US 522 travels concurrently to southeast of Winchester.

: {{jct|country=USA|I|81}} in Winchester

: {{jct|country=USA|US|340}} in Waterloo

: {{jct|country=USA|US|15}} in Gilberts Corner

: {{jct|country=USA|I|66}} in Fair Oaks

: {{jct|country=USA|US|29}} in Fairfax. The highways travel concurrently through the city.

: {{jct|country=USA|I|495|dab1=Capital Beltway}} on the Annandale–Merrifield–West Falls Church line

;District of Columbia

: {{jct|country=USA|I|66}} in Washington, D.C.. The highways travel concurrently through the city, to the Foggy Bottom neighborhood.

: {{jct|country=USA|US|1}} in Washington, in the National Mall. The highways travel concurrently to Mount Vernon Square.

: {{jct|country=USA|I|395|dab1=District of Columbia–Virginia}} in Washington, in Mount Vernon Square

;Maryland

: {{jct|country=USA|I|95|I|495|dab2=Capital Beltway}} in Lanham. The unsigned I-595 is entirely concurrent with US 50 from here to Annapolis.

: {{jct|country=USA|US|301}} in Bowie. The highways travel concurrently to southwest of Queenstown.

: {{jct|country=USA|I|97}} in Parole

: {{jct|country=USA|US|13}} in Salisbury. The highways travel concurrently around the northeastern corner of the city.

: {{jct|country=USA|US|113}} in Berlin

: {{jct|state=MD|MD|528}} in Ocean City

{{cite book |author = Rand McNally |year = 2014 |title = The Road Atlas |edition = Walmart |location = Chicago |publisher = Rand McNally |pages = 12, 20-21, 33, 37, 40-41, 46-47, 58-59, 64, 81-81, 102-103, 107, 111-112|isbn = 978-0-528-00771-2}}

• U.S. Bicycle Route 50

• U.S. Route 150
• U.S. Route 250
• U.S. Route 350
• U.S. Route 450
• U.S. Route 550
• U.S. Route 650
• Special routes of U.S. Route 50

{{Reflist|group=note}}

{{Reflist|30em}}

{{Attached KML|display=title,inline}}

{{Commons category|U.S. Route 50}}

• [http://usends.com/50.html Endpoints of U.S. Highway 50]
• Kansas Highway Maps: [http://www.ksdot.org/burtransplan/maps/MapsState.asp Current], [http://www.ksdot.org/burtransplan/maps/HistoricStateMaps.asp Historic], KDOT

{{US Highways}}

{{US 50}}

{{good article}}

50