UBR4

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

E3 ubiquitin-protein ligase UBR4 is an enzyme that in humans is encoded by the UBR4 gene.{{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S | title = Complete sequencing and characterization of 21,243 full-length human cDNAs | journal = Nat Genet | volume = 36 | issue = 1 | pages = 40–45 |date=Dec 2003 | pmid = 14702039 | doi = 10.1038/ng1285 | doi-access = free }}{{cite journal |vauthors=Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Res | volume = 7 | issue = 1 | pages = 65–73 |date=Apr 2000 | pmid = 10718198 | doi =10.1093/dnares/7.1.65 | doi-access = free }}{{cite journal |vauthors=Tasaki T, Mulder LC, Iwamatsu A, Lee MJ, Davydov IV, Varshavsky A, Muesing M, Kwon YT | title = A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons | journal = Mol Cell Biol | volume = 25 | issue = 16 | pages = 7120–7136 |date=Aug 2005 | pmid = 16055722 | pmc = 1190250 | doi = 10.1128/MCB.25.16.7120-7136.2005 }}{{cite web | title = Entrez Gene: ZUBR1 zinc finger, UBR1 type 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23352}}

References

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Further reading

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  • {{cite journal | author=Andersson B |title=A "double adaptor" method for improved shotgun library construction |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–113 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 |name-list-style=vanc| author2=Wentland MA | author3=Ricafrente JY | display-authors=3 | last4=Liu | first4=W | last5=Gibbs | first5=RA }}
  • {{cite journal | author=Yu W |title=Large-scale concatenation cDNA sequencing |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi= 10.1101/gr.7.4.353| pmc=139146 |name-list-style=vanc| author2=Andersson B | author3=Worley KC | display-authors=3 | last4=Muzny | first4=DM | last5=Ding | first5=Y | last6=Liu | first6=W | last7=Ricafrente | first7=JY | last8=Wentland | first8=MA | last9=Lennon | first9=G }}
  • {{cite journal | author=Seki N |title=Characterization of cDNA clones in size-fractionated cDNA libraries from human brain |journal=DNA Res. |volume=4 |issue= 5 |pages= 345–349 |year= 1998 |pmid= 9455484 |doi=10.1093/dnares/4.5.345 |name-list-style=vanc| author2=Ohira M | author3=Nagase T | display-authors=3 | last4=Ishikawa | first4=K | last5=Miyajima | first5=N | last6=Nakajima | first6=D | last7=Nomura | first7=N | last8=Ohara | first8=O | doi-access=free }}
  • {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–16903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-style=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal | author=Huh KW |title=Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600 |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 32 |pages= 11492–11497 |year= 2005 |pmid= 16061792 |doi= 10.1073/pnas.0505337102 | pmc=1182135 |name-list-style=vanc| author2=DeMasi J | author3=Ogawa H | display-authors=3 | last4=Nakatani | first4=Y | last5=Howley | first5=PM | last6=Münger | first6=K |bibcode=2005PNAS..10211492H |doi-access=free }}
  • {{cite journal | author=Nakatani Y |title=p600, a unique protein required for membrane morphogenesis and cell survival |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 42 |pages= 15093–15098 |year= 2005 |pmid= 16214886 |doi= 10.1073/pnas.0507458102 | pmc=1247991 |name-list-style=vanc| author2=Konishi H | author3=Vassilev A | display-authors=3 | last4=Kurooka | first4=H | last5=Ishiguro | first5=K | last6=Sawada | first6=J | last7=Ikura | first7=T | last8=Korsmeyer | first8=SJ | last9=Qin | first9=J |doi-access=free }}
  • {{cite journal | author=Lennerz V |title=The response of autologous T cells to a human melanoma is dominated by mutated neoantigens |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 44 |pages= 16013–16018 |year= 2005 |pmid= 16247014 |doi= 10.1073/pnas.0500090102 | pmc=1266037 |name-list-style=vanc| author2=Fatho M | author3=Gentilini C | display-authors=3 | last4=Frye | first4=RA | last5=Lifke | first5=A | last6=Ferel | first6=D | last7=Wölfel | first7=C | last8=Huber | first8=C | last9=Wölfel | first9=T |bibcode=2005PNAS..10216013L |doi-access=free }}
  • {{cite journal | author=Ewing RM |title=Large-scale mapping of human protein-protein interactions by mass spectrometry |journal=Mol. Syst. Biol. |volume=3 |issue= 1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 | pmc=1847948 |name-list-style=vanc| author2=Chu P | author3=Elisma F | display-authors=3 | last4=Li | first4=Hongyan | last5=Taylor | first5=Paul | last6=Climie | first6=Shane | last7=McBroom-Cerajewski | first7=Linda | last8=Robinson | first8=Mark D | last9=O'Connor | first9=Liam }}

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