USS Grayback
{{Italic title prefixed|3}}
USS Grayback may refer to the following vessels of the United States Navy:
- {{USS|Grayback|SS-208}}, a {{sclass|Tambor|submarine}}, commissioned in 1941 and sunk in 1944
- {{USS|Grayback|SSG-574}}, a {{sclass|Grayback|submarine|2}}, commissioned in 1958 and stricken in 1984
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