UnaL2 LINE 3′ element

{{Infobox rfam

| Name = UnaL2 LINE 3′ element

| image = RF00436.jpg

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| caption = Predicted secondary structure and sequence conservation of UnaL2

| Symbol = UnaL2

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| Rfam = RF00436

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| RNA_type = Cis-reg

| Tax_domain = Eukaryota

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| SO = {{SO|0000233}}

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The UnaL2 LINE 3′ element is an RNA element found in the UnaL2 LINE (long interspersed nuclear element) and partner SINE (short interspersed nuclear element) from eel.{{cite journal | vauthors = Baba S, Kajikawa M, Okada N, Kawai G | title = Solution structure of an RNA stem-loop derived from the 3′ conserved region of eel LINE UnaL2 | journal = RNA | volume = 10 | issue = 9 | pages = 1380–1387 | date = September 2004 | pmid = 15273327 | pmc = 1370625 | doi = 10.1261/rna.7460104 }} This conserved element is a stem-loop that is critical for their retrotransposition found in their 3′ end. The first step of retrotransposition is the recognition of their 3′ tails by UnaL2-encoded reverse transcriptase. The NMR structure of a 17-nucleotide RNA derived from the 3′ tail of UnaL2 has been determined.