User:Colin/ExistingPrices
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This page contains extracts of cost or price information from 530 drug articles as of 30 Dec 2019.
=[[Abacavir]]=
The wholesale cost in the developing world as of 2014 is between US$0.36 and US$0.83 per day.{{cite web|title=International Drug Price Indicator Guide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=975&searchYear=2014|website=ERC|access-date=20 November 2016}} As of 2016 the wholesale cost for a typical month of medication in the United States is US$70.50.{{cite web|title=NADAC as of 2016-12-07 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services|access-date=12 December 2016|df=dmy-all }}
=[[Abacavir/lamivudine]]=
The wholesale cost in the developing world is about US$14.19 to $16.74 per month as of 2014.{{cite web|title=
Abacavir + Lamivudine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1276&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=28 November 2016}} As of 2015 the cost for a typical month of medication in the United States is more than $200.TarasconPP2015, page 59
=[[Abiraterone]]=
In the United Kingdom it costs the NHS £2,735 a month as of 2018.BNF76, page 921 In the United States this amount costs US$3,276 as of 2019.{{cite web |title=Abiraterone Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/abiraterone |website=Drugs.com |language=en}} The medication is marketed widely throughout the world.{{cite web | title = Abiraterone | url = https://www.drugs.com/international/abiraterone.html | work = Drugs.com }}
==Cost==
In the United Kingdom it costs the NHS £2,735 a month as of 2018. In the United States this amount costs US$3,276 as of 2019. A generic version is available in India at a price of US$238 a month as of 2019.{{cite web |title=PROPOSAL FOR THE INCLUSION OF ENZALUTAMIDE AND ABIRATERONE ACETATE IN THE WHO MODEL LIST OF ESSENTIAL MEDICINES FOR THE TREATMENT OF METASTATIC CASTRATION RESISTANT PROSTATE CANCER |url=https://www.who.int/selection_medicines/committees/expert/22/applications/8.3_enzalutamide-abiraterone.pdf |accessdate=26 November 2019|page=22, 25}}
=[[Acetaminophen/butalbital]]=
In the United States the wholesale cost is about 1.20 USD per dose as of 2019.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Acetazolamide]]=
The wholesale cost in the developing world is about US$1.40–16.93 per month.{{cite web|title=Acetazolamide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States the wholesale cost is about US$125.34 per month.{{cite web|title=NADAC as of 2016-12-07 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services|accessdate=28 December 2016}}
=[[Aciclovir]]=
The wholesale cost as of 2014 to 2016 was between US$0.03 and US$0.12 for a typical dose by mouth.{{cite web|title=Aciclovir|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1016&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=6 September 2015}}{{cite web|title=Pharmacy Pricing|url=https://www.medicaid.gov/Medicaid-CHIP-Program-Information/By-Topics/Benefits/Prescription-Drugs/Pharmacy-Pricing.html|website=Medicaid|accessdate=8 March 2016|date=March 2016}} The cost of a typical course of treatment in the United States is less than US$25.TarasconPP2015, page 59
==Cost==
=[[Activated charcoal (medication)]]=
The wholesale costs in the developing world is between US$0.46 and US$0.86 per dose.{{cite web|title=Charcoal, Activated|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=141&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=13 August 2015}} In the United States a course of treatment costs less than US$25.TarasconPP2015, page 469
=[[Adalimumab]]=
A month supply in the United Kingdom costs the NHS about £704.28 as of 2018.BNF76, page 1074 In the United States the wholesale cost of this amount is about {{US$|5,041.12}}.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 }} In 2014, a biosimilar came to market in India at a price of {{US$|400}} per month.{{cite news |title=India's Cadila launches first cheaper copy of world's top-selling drug |url=https://www.reuters.com/article/us-cadila-health-humira-india/indias-cadila-launches-first-cheaper-copy-of-worlds-top-selling-drug-idUSKBN0JN0X820141209 |access-date=19 March 2019 |agency=Reuters |date=9 December 2014}}
=[[Albendazole]]=
The wholesale cost in the developing world is between 0.01 and US$0.06 per dose.{{cite web|title=Albendazole|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=12&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=August 18, 2015}} In the United States, as of 2019, the wholesale cost is about US$128 per dose.{{cite web |title=NADAC as of 2019-06-05 {{!}} Data.Medicaid.gov |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-06-05/33wi-gdcd |website=Centers for Medicare and Medicaid Services |accessdate=10 June 2019 |language=en}}
== Cost ==
In many areas of the world it costs between US$0.01 and US$0.06 per dose. In the United States, however, it costs about US$50 per dose, as of 2014.TarasconPP2014, page 40
In Raleigh, North Carolina, the brand-name prescription cost was around US$800, and US$540 for the generic. The pharmaceutical company Amedra increased the price after purchasing the rights to the drug, instead of lowering it as generics are predicted to do, drawing criticism from patients' rights advocates and US Democratic Party leaders.{{cite web | last=Greene | first=Jeremey A. | title=Generic drug price gouging: How Shkreli and other monopolists cornered the market on essential medications | work=Slate | url=http://www.slate.com/articles/health_and_science/medical_examiner/2015/09/generic_drug_price_gouging_how_shkreli_and_other_monopolists_cornered_the.html | date=2015-09-23 }}
=[[Alcohols (medicine)]]=
The wholesale cost in the developing world is about US$1.80–9.50 per litre of 70% denatured ethanol.{{cite web|title=Alcohol, Denatured |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1117&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom it costs the NHS about 3.90 GBP per liter of 99% denatured alcohol.BNF69, pages 42, 838
=[[Alendronic acid]]=
In the United Kingdom, a month of medication costs the NHS about 0.41 pounds as of 2019.BNF76, pages 710–711 In the United States, the wholesale cost is about US$1.16 per month.{{cite web |title=NADAC as of 2019-01-30 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-01-30/2c5s-3kst |website=Centers for Medicare and Medicaid Services |accessdate=2 February 2019 |language=en}}
=[[Allopurinol]]=
The wholesale cost in the developing world is about US$0.81–3.42 per month.{{cite web|title=Allopurinol|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=19&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a month of treatment costs less than $25.TarasconPP2015, page 465
=[[Alprazolam]]=
The wholesale cost in the United States is less than {{US$}}0.03 per dose as of 2018.{{cite web |title=NADAC as of 2018-10-24 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-10-24/95jf-evmp |website=Centers for Medicare and Medicaid Services |access-date=26 October 2018 }} In 2016, it was the 19th most prescribed medication in the United States, with more than 27 million prescriptions.{{cite web |title=The Top 300 of 2019 |url=https://clincalc.com/DrugStats/Top300Drugs.aspx |website=clincalc.com |access-date=22 December 2018}}
=[[Alteplase]]=
In the United Kingdom it costs about £864 per treatment as of 2018.BNF76, page 216 In the United States this amount costs about US$9,197 as of 2019.{{cite web |title=Activase Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/activase |website=Drugs.com |accessdate=12 November 2019 |language=en}}
==Society and culture==
=[[Amikacin]]=
The wholesale cost in the developing world is 13.80 to US$130.50 for a month.{{cite web|title=Amikacin Sulfate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=879&searchYear=2014|website=International Drug Price Indicator Guide |accessdate=8 December 2016}} In the United States a typical course of treatment costs 25 to US$50.TarasconPP2015, page 35
=[[Amiodarone]]=
In the developing world the wholesale cost as of 2014 is about US$0.06–0.26 per day.{{cite web|title=Amiodarone|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=34&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=22 August 2016}} In the United States a typical month supply is between $100 and $200.TarasconPP2015, page 124
=[[Amitriptyline]]=
The wholesale cost in the developing world {{as of|lc=1|2014}} was between 0.01 and US$0.04 per dose.{{cite web|title=Amitriptyline|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=36&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=2 December 2015}} In the United States, it costs about US$0.20 per dose.{{cite web|title=Amitriptyline Hydrochloride|url=https://www.drugs.com/monograph/amitriptyline-hydrochloride.html|publisher=The American Society of Health-System Pharmacists|accessdate=25 September 2014}}
=[[Amlodipine]]=
Wholesale cost in the developing world is US$0.003 to 0.066 per day for a typical dose as of 2015.{{cite web|title=Amlodipine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1029&searchYear=2015|website=International Drug Price Indicator Guide|accessdate=23 July 2016|df=dmy-all}} In the United States, a month's supply costs less than $25.TarasconPP2015, page 154
=[[Amlodipine/benazepril]]=
A month supply in the United States has a wholesale cost of about US$4.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Amodiaquine]]=
The wholesale cost is about US$0.01 per dose as of 2014.{{cite web|title=Amodiaquine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=39&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=4 December 2015}}
=[[Amoxicillin]]=
It has a wholesale cost in the developing world of between US$0.02 and $0.05 per pill.{{cite web|title=Amoxicillin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=42&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=1 August 2015}} In the United States, ten days of treatment costs about US$16 ($0.40 per pill).{{cite web|title=Amoxicillin|url=https://www.drugs.com/monograph/amoxicillin.html|work=The American Society of Health-System Pharmacists|accessdate=1 August 2015}}
=[[Amoxicillin/clavulanic acid]]=
The wholesale cost in the developing world is about US$0.18–1.14 per day.{{cite web|title=Amoxicillin + Clavulanic Acid|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=44&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a course of treatment costs $50–100.TarasconPP2015, page 97
=[[Ampicillin]]=
Its wholesale cost in the developing world is between US$0.13 and 1.20 for a vial of the intravenous solution as of 2014.{{cite web|title=Ampicillin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=50&searchYear=2014|website=International Drug Price Indicator Guide|access-date=1 August 2015|df=dmy-all}} In the United States, it is available as a generic medication and 10 days of treatment cost about $13.{{cite web|title=Ampicillin|url=https://www.drugs.com/monograph/ampicillin.html|publisher=The American Society of Health-System Pharmacists|access-date=1 August 2015|df=dmy-all}}
=Cost=
{{As of|2014}}, ampicillin's wholesale cost is between US$0.13 and 1.20 for a vial of the intravenous solution. In the United States, it is available as a generic medication: 10 days of treatment cost about $13.
=[[Anastrozole]]=
The wholesale cost in the developing world is about US$1.92–30.60 a month.{{cite web|title=Anastrozole|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1049&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United States the wholesale cost is about $3.81 per month.{{cite web|title=NADAC as of 2016-12-07 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services|access-date=18 December 2016}}
=[[Anti-tetanus immunoglobulin]]=
The wholesale cost in the developing world for the horse version is about US$0.90–3.60 per 1500 iu vial, while the human version is US$10.00–46.86 for 250 iu.{{cite web|title=Tetanus Antitoxin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=752&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}{{cite web|title=Immunoglobulin Prices 2013 - PAHO/WHO|url=http://www.paho.org/hq/index.php?option=com_docman&task=doc_download&Itemid=270&gid=20805&lang=en|website=PAHO|accessdate=8 January 2017}}{{cite web|title=Immunoglobulin, Anti-Tetanus|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=753&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a course of treatment costs about $100–200.TarasconPP2015, page 320
=[[Antivenom]]=
Depending on the type, the wholesale cost in the developing world is US$9.00–US$118.80 per vial.{{cite web|title=Antivenom Serum|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=62&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States, the wholesale cost is as high as $2,300 per dose.{{cite news|last1=Lewis|first1=Danny|title=Why A Single Vial Of Antivenom Can Cost $14,000|url=http://www.smithsonianmag.com/smart-news/why-single-vial-antivenom-can-cost-14000-180956564/|accessdate=9 January 2017|work=Smithsonian|date=11 September 2015}}{{cite news|title=One step closer to cheaper antivenom|url=https://www.sciencedaily.com/releases/2015/09/150903131719.htm|accessdate=9 January 2017|work=ScienceDaily|date=3 September 2015}}
=[[Apixaban]]=
A month supply in the United Kingdom costs the NHS about £57 as of 2019.BNF76, pages 124-125 In the United States the wholesale cost of this amount is about $427.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 }}
=[[Aprepitant]]=
In the United States it about US$230 per dose.{{cite web |title=Emend Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/emend |website=Drugs.com |accessdate=13 October 2019 |language=en}} This amount in the United Kingdom cost the NHS about £16.{{cite web |title=Aprepitant {{!}} Medicinal forms {{!}} BNFc content published by NICE |url=https://webcache.googleusercontent.com/search?q=cache:ZvX-BZ3knqcJ:https://bnfc.nice.org.uk/medicinal-forms/aprepitant.html+&cd=10&hl=en&ct=clnk&gl=ca |website=webcache.googleusercontent.com |publisher=NICE |accessdate=13 October 2019}}
=[[Aripiprazole]]=
In the United Kingdom, a month's supply costs the NHS about £2.75 as of 2019.BNF76, page 392 In the United States, the wholesale cost of this amount is 10 USD.{{cite web |title=NADAC as of 2019-02-20 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-20/4nuv-8qfq |website=Centers for Medicare and Medicaid Services |accessdate=26 February 2019 |language=en}}
=[[Arsenic trioxide]]=
In the United Kingdom it costs the NHS £292 a dose as of 2018.BNF76, page 907 In the United States this amount costs about US$508 as of 2019.{{cite web |title=Arsenic trioxide Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/arsenic-trioxide |website=Drugs.com |accessdate=16 November 2019 |language=en}}
==Cost==
In the United Kingdom it costs the NHS £292 a dose as of 2018. In the United States this amount costs about US$508 as of 2019. With initial treatment being 60 days the cost for a course of treatment is £17,520 and US$30,000 respectively.
=[[Artemether]]=
The wholesale cost in the developing world is between US$0.38 and US$16.47 per vial.{{cite web|title=Artemether|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=65&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=1 January 2016}} The combination form costs between US$100 and US$200 for a course of treatment in the United States.TarasconPP2015, page 45
=[[Artemether/lumefantrine]]=
The wholesale cost in the developing world is between US$0.10 and US$1.2 per day as of 2014.{{cite web|title=Artemether + Lumefantrine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1441&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=4 December 2015}}{{dead link|date=September 2017 |bot=InternetArchiveBot |fix-attempted=yes }} It is not available as a generic medication and a course of treatment costs between US$100 and US$200 in the United States.TarasconPP2015, page 45
=[[Artesunate]]=
The wholesale cost in the developing world is US$2.09 to US$2.57 a dose.{{cite web|title=Artesunate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1282&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=1 January 2016}}
=[[Artesunate/amodiaquine]]=
The wholesale cost in the developing world is about US$0.85 to US$1.52 for a course of treatment.{{cite web|title=Artesunate + Amodiaquine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1447&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Asparaginase]]=
The wholesale cost in the developing world is about US$42.00 per 10,000 IU vial.{{cite web|title=Asparaginase|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=69&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} This amount in the United Kingdom costs the NHS 613.00 pounds.BNF69, page 600
=[[Aspirin]]=
{{As of|2014}}, the wholesale cost in the developing world is {{US$|link=yes}}0.002 to {{US$}}0.025 per dose.{{cite web|title=Acetylsalicylic Acid|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=3&searchYear=2014|website=International Drug Price Indicator Guide|access-date=30 August 2016}} {{As of|2015}}, the cost for a typical month of medication in the United States is less than {{US$}}25.00.TarasconPP2015, page 5
=[[Atenolol]]=
Atenolol was patented in 1969 and approved for medical use in 1975.{{cite book|last1=Fischer|first1=Janos|last2=Ganellin|first2=C. Robin|title=Analogue-based Drug Discovery|date=2006|publisher=John Wiley & Sons|isbn=9783527607495|page=461|url=https://books.google.ca/books?id=FjKfqkaKkAAC&pg=PA461|language=en}} It is available as a generic medication.{{cite web |title=Atenolol Monograph for Professionals |url=https://www.drugs.com/monograph/atenolol.html |website=Drugs.com |publisher=AHFS |accessdate=23 December 2018 |language=en}} In the United States, the wholesale cost per month is less than 15 USD as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}} In the United Kingdom, a month of treatment costs the NHS less than 5 pounds.BNF76, pages 151–153
=[[Atenolol/chlorthalidone]]=
A month supply in the United Kingdom costs the NHS less than 2 £ as of 2019.BNF76, page 153 In the United States the wholesale cost of this amount is about US$12.30.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Atomoxetine]]=
A month's supply in the United Kingdom costs the NHS about £53 as of 2019.BNF76, pages 344–345 In the United States, the wholesale cost of this amount is about US$77.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 |language=en |df=dmy-all }}
=[[Atorvastatin]]=
In the United States, the wholesale cost per month is about 3.80 USD as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |access-date=22 December 2018 }} In the United Kingdom, it costs the NHS about £0.70 per month as of 2018.BNF76, pages 200–201
=[[Atovaquone/proguanil]]=
In the United Kingdom it costs £2.10 per dose as of 2019.BNF76, page 604 The wholesale cost in the United States is $US 2.82 per dose as of 2019.{{cite web |title=NADAC as of 2019-09-11 {{!}} Data.Medicaid.gov |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-09-11/xh57-kaa3 |website=Centers for Medicare and Medicaid Services |accessdate=12 September 2019 |language=en}}
=[[Atracurium besilate]]=
The wholesale cost in the developing world is about US$1.69–1.87 per dose.{{cite web|title=Atracurium|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=74&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Atropine]]=
It is available as a generic medication and is not very expensive.{{cite web|title=Atropine|url=https://www.drugs.com/monograph/atropine.html|publisher=The American Society of Health-System Pharmacists|accessdate=Aug 13, 2015}}TarasconPP2014, page 386 A one-milligram vial costs between US$0.06 and US$0.44, wholesale, in the developing world.{{cite web|title=Atropine Sulfate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=78&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=13 August 2015}}
=[[Atropine/diphenoxylate]]=
In the United States the wholesale cost per is dose is US$0.31.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Azathioprine]]=
The wholesale cost in the developing world is about US$7.63–17.19 a month.{{cite web|title=Azathioprine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=82&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} The wholesale cost in the United States is about US$35.34 per month.{{cite web|title=NADAC as of 2016-12-07 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services|accessdate=20 December 2016}}
=[[Azelastine]]=
A 22 millilitre bottle in the United Kingdom costs the NHS about £10.50 as of 2019.BNF76, page 1169 In the United States the wholesale cost of this amount is about US$8.40.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Azithromycin]]=
The wholesale cost in the developing world is about {{US$}}0.18 to {{US$}}2.98 per dose.{{cite web|title=Azithromycin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1062&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=4 September 2015}} In the United States, it is about {{US$}}4 for a course of treatment {{as of|2018|lc=y}}.{{cite web|title=NADAC as of 2018-05-23|url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-05-23/5kr5-j2di|website=Centers for Medicare and Medicaid Services|accessdate=24 May 2018|language=en}}
==Cost==
=[[BCG vaccine]]=
Between 2011 and 2014 the wholesale price was US$0.16 to US$1.11 a dose in the developing world.{{cite web|title=Vaccine, Bcg|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=788&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=6 December 2015}}{{dead link|date=September 2017 |bot=Level C |fix-attempted=yes }}{{cite web|title=Vaccine, Bcg|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=788&searchYear=2014|website=ERC|accessdate=13 June 2016}} In the United States it costs US$100 to US$200.TarasconPP2015, page 312
=[[Baclofen]]=
A month supply in the United Kingdom costs the NHS about £1 as of 2019.BNF76, page 1092 In the United States the wholesale cost of this amount is about US$8.40.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Barium sulfate suspension]]=
The wholesale cost in the developing world is about US$37.80–79.33 per kilogram.{{cite web|title=Barium Sulfate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=84&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a course of treatment is not very expensive.TarasconPP2015, page 171
=[[Beclometasone]]=
The wholesale price in the developing world for an inhaler containing 200 doses of medication is about US$3.20 as of 2014.{{cite web|title=Beclometasone|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1004&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=6 December 2015}} In the United States it costs US$50–100 for a typical month supply of the inhaled form.TarasconPP2015, page 451
=[[Benazepril]]=
A month supply in the United States costs about US$1.32 as of 2019.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Benzathine benzylpenicillin]]=
The wholesale cost in the developing world is about 0.27 to 1.71 USD for a course of treatment.{{cite web|title=Penicillin, Benzathine Benzyl|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=596&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States the medication costs 50 to 100 USD for a dose as of 2015.TarasconPP2015, page 94 In the United Kingdom it costs the NHS about 0.95 to 1.89 pounds a dose as of 2015.BNF 69, page 367
=[[Benzatropine]]=
In the United States the wholesale cost is about 6 USD per month.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Benzonatate]]=
In the United States the wholesale cost of is about 0.12 USD per dose.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Benzoyl peroxide/clindamycin]]=
Currently Duac costs $362.69 for 45 grams in the US (significantly less elsewhere, eg. $15 for 60 grams in Poland{{Cite web|url=https://indeks24.pl/leki/duac-zel-10-mg-g-50-mg-g-tuba-60-g,32904|title=Duac żel(10 mg/g+50 mg/g) - tuba 60 g - wyszukiwarka i baza leków - Indeks24.pl|website=indeks24.pl|language=pl|access-date=2019-08-13}}) and Onexton costs $477.74 for 50 grams.{{Cite web|url=https://www.drugs.com/price-guide/duac|title=Duac Prices, Coupons & Patient Assistance Programs - Drugs.com|website=www.drugs.com|access-date=2016-11-19}}{{Cite web|url=https://www.drugs.com/price-guide/onexton|title=Onexton Prices, Coupons & Patient Assistance Programs - Drugs.com|website=www.drugs.com|access-date=2016-11-19}}
=[[Benzyl benzoate]]=
The wholesale cost in the developing world is about US$0.21–0.53 per 100 mL.{{cite web|title=Benzyl Benzoate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=91&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom it costs the NHS about £2.50 for 500 mL.BNF69, page 836
=[[Benzylpenicillin]]=
The wholesale cost in the developing world is about US$0.24–2.72 per day.{{cite web|title=Penicillin, Benzyl|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=599&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a course of treatment costs $100–200.TarasconPP2015, page 95
=[[Bevacizumab]]=
The wholesale cost in the developing world is about {{US$}}638.54 per vial.{{cite web|title=Bevacizumab |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1676&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} This dose in the United Kingdom cost the NHS about £242.66 in 2015.BNF69, page 597
==Costs==
In countries with national health care systems (such as the UK and Canada), many of those national health services have restricted bevacizumab on the basis of cost-benefit calculations; in the U.K., for example, the National Institute for Health and Care Excellence has taken the position that bevacizumab should not be funded by the NHS because it costs nearly £21,000 per patient but only minimal benefit in many cancers.{{cite news|url=https://www.bbc.co.uk/news/health-11060968|title=Critics condemn bowel cancer drug rejection|author=Briggs, Helen (BBC News Health Reporter)|access-date=2010-08-24|date=August 24, 2010}} In 2006, the Scottish Medicines Consortium recommended against the NHS funding Avastin for first-line treatment of metastatic carcinoma of the colon or rectum, due to estimated costs of £24,000 to £93,000 per quality-adjusted life year (QALY).{{cite web|title=Bevacizumab|url=http://www.scottishmedicines.org.uk/files/bevacizumab__Avastin__Resubmissionn_May_06_FINAL_for_website.pdf|publisher=Scottish Medicines|access-date=18 July 2012}}
The addition of bevacizumab to standard treatment can prolong the lives of lung cancer patients by several months, at a cost of $100,000 a year in the United States.{{cite news |author=Berenson, Alex |title=A Cancer Drug Shows Promise, at a Price That Many Can't Pay |newspaper=The New York Times |date=February 15, 2006 |url=https://www.nytimes.com/2006/02/15/business/15drug.html }} For colorectal cancer, Robert J. Mayer wrote in the New England Journal of Medicine that bevacizumab extended life by 4.7 months (20.3 months vs. 15.6 months) in the initial study, at a cost of $42,800 to $55,000.{{cite journal | vauthors = Mayer RJ | title = Two steps forward in the treatment of colorectal cancer | journal = The New England Journal of Medicine | volume = 350 | issue = 23 | pages = 2406–8 | date = June 2004 | pmid = 15175443 | doi = 10.1056/NEJMe048098 }} Costs in other countries vary; in Canada it is reported to cost $40,000 CAD per year.{{cite news |title=P.E.I. sole holdout on cancer drug |newspaper=CBC News |date=November 26, 2009 |url=http://www.cbc.ca/news/canada/prince-edward-island/p-e-i-sole-holdout-on-cancer-drug-1.843966 }}
On September 16, 2014 Genentech reclassified bevacizumab as a specialty drug which are only available through specialty pharmacies. "Specialty drugs usually fall under the FDA’s Risk Evaluation and Mitigation Strategy (REMS) program, established for compounds like the testosterone... that may have unusual side effects; or for drugs that are unusually expensive." This has caused concern to hospitals as the price increased.{{cite web | url=http://time.com/3541484/cancer-drug-price-hikes/ | title=Hospitals Furious at Cancer-Drug Price Hikes | work=Time | date=27 October 2014 | access-date=26 October 2015 | author=Saporito, Bill }} According to IMS Health, the average price charged by hospitals for bevacizumab is approximately $9000 compared to approximately $2300 when administered in a doctor's office. As a result of the new distribution arrangement, many hospitals will no longer be eligible for the 51% discount to average wholesale price that was mandated by the Affordable Healthcare Act under the old distribution arrangement.{{cite web|url=http://www.imshealth.com/portal/site/imshealth/menuitem.762a961826aad98f53c753c71ad8c22a/?vgnextoid=f8d4df7a5e8b5410VgnVCM10000076192ca2RCRD&vgnextchannel=736de5fda6370410VgnVCM10000076192ca2RCRD&vgnextfmt=default|title=Innovation in Cancer Care and Implications for Health Systems: Global Oncology Trend Report | Reports}}
When bevacizumab is used in the treatment of wet age-related macular degeneration (wet AMD), only tiny and relatively inexpensive doses (compared to amounts used in colon and other cancers) are required. Some investigators reported in 2010 that bevacizumab at a cost of around $42 a dose is as effective as ranibizumab at a cost of over $1,593 a dose.{{cite news |title=Medicare Eye Study Finds Untapped Savings |newspaper=Wall Street Journal |date=June 17, 2010 |url=https://www.wsj.com/articles/SB20001424052748703513604575311070894017154 |first=Alicia |last=Mundy}}{{cite journal | vauthors = Tufail A, Patel PJ, Egan C, Hykin P, da Cruz L, Gregor Z, Dowler J, Majid MA, Bailey C, Mohamed Q, Johnston R, Bunce C, Xing W | title = Bevacizumab for neovascular age related macular degeneration (ABC Trial): multicentre randomised double masked study | journal = BMJ | volume = 340 | pages = c2459 | date = June 2010 | pmid = 20538634 | doi = 10.1136/bmj.c2459 | url = http://www.bmj.com/cgi/reprint/340/jun09_4/c2459 }}
=[[Bicalutamide]]=
The wholesale cost in the developing world is about {{currency|7.07|USD}} to {{currency|144.22|USD}} per month.{{cite web |title=Bicalutamide |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1213&searchYear=2014 |website=International Drug Price Indicator Guide |accessdate=8 December 2016}} In the United States it costs about {{currency|10.00|USD}} and above per month.{{cite web |title=NADAC as of 2016-12-07 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services|accessdate=17 January 2017|df=dmy-all}}
==Cost and generics==
Bicalutamide is off-patent and available as a generic, and its cost is low in comparison to a number of other similar medications (from {{currency|10.00|USD|linked=no}} to {{currency|15.44|USD|linked=no}} for a 30-day supply of once-daily 50 mg tablets).{{cite web |url=https://www.drugs.com/price-guide/bicalutamide |title=Bicalutamide Prices, Coupons and Patient Assistance Programs |publisher=Drugs.com |accessdate=31 August 2015 |df=dmy-all}} Brand name Casodex costs {{currency|556.17|USD|linked=no}} for a 30-day supply of once-daily 50 mg tablets {{as of|2017|lc=y}}.{{cite web |url=https://www.drugs.com/price-guide/casodex |title=Casodex Prices, Coupons and Patient Assistance Programs |work=Drugs.com |df=dmy-all}} Unlike bicalutamide, the newer {{abbr|NSAA|nonsteroidal antiandrogen}} enzalutamide is still on-patent, and for this reason, is considerably more expensive in comparison ({{currency|7,450|USD|linked=no}} for a 30-day supply {{as of|2015|lc=y}}).{{cite journal |vauthors=Ramadan WH, Kabbara WK, Al Basiouni Al Masri HS |title=Enzalutamide for patients with metastatic castration-resistant prostate cancer |journal=OncoTargets and Therapy |volume=8 |pages=871–6 |year=2015 |pmid=25945058 |doi=10.2147/OTT.S80488 |pmc=4407758}}
Bicalutamide is considerably less costly than {{abbr|GnRH|gonadotropin-releasing hormone}} analogues, which, in spite of some having been off-patent many years, have been reported (in 2013) to typically cost {{currency|10,000|USD|linked=no}}–$15,000 per year (or about {{currency|1,000|USD|linked=no}} per month) of treatment.{{cite book |first1=S. Jean |last1=Emans |first2=Marc R. |last2=Laufer|name-list-style=vanc |title=Emans, Laufer, Goldstein's Pediatric and Adolescent Gynecology |url=https://books.google.com/books?id=pdNh7ieMJzQC&pg=PT365 |date=5 January 2012 |publisher=Lippincott Williams & Wilkins |isbn=978-1-4511-5406-1 |pages=365–|quote=Therapy with GnRH analogs is expensive and requires intramuscular injections of depot formulations, the insert of a subcutaneous implant yearly, or, much less commonly, daily subcutaneous injections. |df=dmy-all}}{{cite book |first=Paula J. Adams |last=Hillard | name-list-style = vanc |title=Practical Pediatric and Adolescent Gynecology |url=https://books.google.com/books?id=vAA5Z5aqlUQC&pg=PT182 |date=29 March 2013 |publisher=John Wiley & Sons |isbn=978-1-118-53857-9 |pages=182–|quote=Treatment is expensive, with costs typicall in the range of $10,000–$15,000 per year.}}
=[[Bimatoprost]]=
A 3{{nbsp}}milliliter bottle in the United Kingdom costs the NHS about 9.30 £ as of 2019.BNF76, page 1149 In the United States the wholesale cost of this amount is about US$80.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare & Medicaid Services (CMS) |accessdate=3 March 2019 }}
=[[Biperiden]]=
The wholesale cost in the developing world is about US$1.52–12.92 per month.{{cite web|title=Biperiden|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=96&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States it costs about $50–100 per month.TarasconPP2015, page 340
=[[Bisoprolol]]=
The wholesale cost in the developing world is about US$2.98–4.94 per month.{{cite web|title=Bisoprolol|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1583&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States, as of 2015, it costs about $25–50 a month.TarasconPP2015, page 151
=[[Bleomycin]]=
The wholesale cost in the developing world is between US$14 and US$78 a dose.{{cite web|title=Bleomycin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=100&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=26 August 2015}}
=[[Bortezomib]]=
In the United States it costs US$1,360 per 3.5 mg vial.{{cite web |title=Bortezomib Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/bortezomib |website=Drugs.com |accessdate=13 October 2019 }} In the United Kingdom this amount costs the NHS £762 such that a course of treatment is about £12,261 as of 2014.{{cite web |title=Bortezomib for induction therapy in multiple myeloma before high-dose chemotherapy and autologous stem cell transplantation |url=https://www.nice.org.uk/guidance/ta311/documents/multiple-myeloma-bortezomib-induction-therapy-fad-document2 |website=NICE |accessdate=13 October 2019 |page=2|date=February 2014}}
=Costs=
In the UK, NICE initially recommended against Velcade in October 2006 due to its cost of about £18,000 per person, and because studies reviewed by NICE reported that it could only extend the life expectancy by an average of six months over standard treatment.{{cite web|url=http://news.bbc.co.uk/1/hi/health/6069386.stm | title=NHS watchdog rejects cancer drug | accessdate=2009-08-14 | publisher=BBC News UK | date=2006-10-20 }} However, the company later proposed a performance-linked cost reduction for multiple myeloma,{{cite web |url=http://www.nice.org.uk/nicemedia/pdf/MyelomaDofHSummaryResponderScheme.pdf |title=Summary of VELCADE Response Scheme |accessdate=2009-08-14 }} and this was accepted.{{cite web | url=http://www.europharmatoday.com/2009/01/more-velcadestyle-risksharing-in-the-uk.html | title=More Velcade-Style Risk-Sharing In The UK? | accessdate=2009-08-14 | publisher=Euro Pharma Today | date=2009-01-21 }}
=[[Bremelanotide]]=
In the United States it is sold for US$948 per dose as of 2019.{{cite web |title=Vyleesi Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/vyleesi |website=Drugs.com |accessdate=21 November 2019 |language=en}}
=[[Brimonidine]]=
One milliliter in the United Kingdom costs the NHS about 1.13 £ as of 2019.BNF76, page 1153 In the United States the wholesale cost of this amount is about US$0.60.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Budesonide]]=
The wholesale price in the developing world for an inhaler containing 200 doses is about US$5 to US$7 as of 2014.{{cite web|title=Budesonide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1406&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=5 December 2015}} As of 2015 the cost for a typical month of the inhaler medication in the United States is US$100 to US$200.TarasconPP2015, page 451 In 2016 it was the 207th most prescribed medication in the United States with more than 2 million prescriptions.{{cite web |title=The Top 300 of 2019 |url=https://clincalc.com/DrugStats/Top300Drugs.aspx |website=clincalc.com |accessdate=22 December 2018}}
=[[Budesonide/formoterol]]=
In the United States, as of 2017, the wholesale cost of an inhaler is about 30 USD.{{cite web|title=NADAC as of 2017-12-13|url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2017-12-13/iqwu-vhmf|website=Centers for Medicare and Medicaid Services|accessdate=13 December 2017}} In the United Kingdom the cost as of 2015 was about 35 pounds for a unit with 120 doses.BNF69, page 202
=[[Bumetanide]]=
A month supply in the United Kingdom costs the NHS about 1.20 £ as of 2019.BNF76, pages 225–226 In the United States the wholesale cost of this amount is about US$12.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Bupivacaine]]=
Bupivacaine is available as a generic medication and is not very expensive.{{cite web|title=Bupivacaine Hydrochloride|url=https://www.drugs.com/monograph/bupivacaine-hydrochloride.html|publisher=The American Society of Health-System Pharmacists|accessdate=Aug 1, 2015}}TarasconPP2015, page 22 The wholesale cost in the developing world of a vial is about US$2.10.{{cite web|title=Bupivacaine HCL|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=103&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=29 August 2015}}
=Cost=
Bupivacaine is available as a generic medication and is not very expensive.TarasconPP2015, page 22 The wholesale cost of a vial of bupivacaine is about US$2.10.
=[[Buprenorphine]]=
For the tablets the wholesale cost in the United States is between {{USD}}0.86 and {{USD}}1.32 per daily dose as of 2017.{{cite web|title=NADAC as of 2017-11-29|url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2017-11-29/pmhw-skdi|website=Centers for Medicare and Medicaid Services|accessdate=3 December 2017|language=en}}
=[[Buprenorphine/naloxone]]=
In the United States the wholesale cost as of 2017 is between {{US$}}2.32 and {{US$}}3.15 per day.{{cite web|title=NADAC as of 2017-11-29|url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2017-11-29/pmhw-skdi|website=Centers for Medicare and Medicaid Services|accessdate=3 December 2017|language=en}} In the United Kingdom a similar dose costs the NHS £0.90 to £2.72 per day, according to 2015 data.BNF69, page 346
==Cost==
In the United States the wholesale cost as of 2017 is between {{US$}}2.32 and {{US$}}3.15 per day. In the United Kingdom a similar dose costs the NHS £0.90 to £2.72 per day, according to 2015 data.
=[[Bupropion]]=
In the United States the wholesale cost per dose is less than US$0.50 as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 }}
=[[Buspirone]]=
A month supply in the United Kingdom costs the NHS about 10 GBP as of 2019.BNF76, page 338 In the United States the wholesale cost of this amount is about 2.65 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Calamine]]=
The wholesale cost in the developing world is about US$0.25–3.85 per 100-ml bottle.{{cite web|title=Calamine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=105&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom, it costs the National Health Service about £0.44.BNF69, page 801
=[[Calcium gluconate]]=
The wholesale cost in the developing world is about US$0.21–1.34 per one-gram vial, 10 ml of 100 mg/ml (10% solution).{{cite web|title=Calcium Gluconate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=109&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom this amount costs the NHS about 0.65 pounds.BNF69, pages 680, 694
=[[Calcium supplement]]=
The wholesale cost in the developing world is about US$0.92–4.76 per month.{{cite web|title=Calcium Lactate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=110&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States treatment generally costs less than $25 per month.TarasconPP2015, pages 215–216
=[[Canagliflozin]]=
A month's supply in the United Kingdom costs the NHS about £39.20 as of 2019.BNF76, page 687 In the United States the wholesale cost of this amount is about {{US$}}475.20.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 |language=en}}
=[[Canakinumab]]=
One 150 mg subcutaneous injection, usually needed every two weeks, costs over $16,700; discounts are sometimes available.https://www.drugs.com/price-guide/ilaris
=[[Capecitabine]]=
The wholesale cost in the developing world is about US$122.64–195.66 per cycle of medication.{{cite web|title=Capecitabine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1037&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom it costs the NHS about £210.67 per cycle.BNF69, pages 585, 588 In the United States it costs about $1,892.00 as of 2016.{{cite web|title=NADAC as of 2016-12-07 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services|accessdate=19 December 2016}}
=[[Capreomycin]]=
The wholesale cost in the developing world is about 6.25 to 8.98 USD a dose.{{cite web|title=Capreomycin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1064&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Carbamazepine]]=
The wholesale cost in the developing world is about US$0.07 to US$0.24 per day as of 2015.{{cite web |title=Carbamazepine |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=117&searchYear=2015 |website=International Medical Products Price Guide |accessdate=26 November 2019}}
=[[Carbidopa/levodopa]]=
The wholesale price in the developing world is about US$1.80 to $3.00 a month.{{cite web|title=Levodopa + Carbidopa|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=462&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=22 August 2015}} In the United States, a month's supply costs about $50 to $150.{{cite web|title=Levodopa/Carbidopa|url=https://www.drugs.com/monograph/levodopa-carbidopa.html|publisher=The American Society of Health-System Pharmacists|accessdate=Aug 21, 2015}}
==Cost==
It is available as a generic medication and is moderately expensive.TarasconPP2013, page 303 Globally, the wholesale price of the medication is about US$1.80 to $3.00 a month. In the United States a month's supply is about $50 to $150.
=[[Carboplatin]]=
The wholesale cost in the developing world is about US$26.49–37.37 per 450 mg vial.{{cite web|title=Carboplatin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1452&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom it costs the National Health Service (NHS) about 160 pounds (around US$200).BNF69, page 605
=[[Carisoprodol]]=
In the United States the wholesale cost is less than US$0.10 per dose.{{cite web |title=NADAC as of 2019-02-27 {{!}} Data.Medicaid.gov |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=8 April 2019 |language=en}}
=[[Carvedilol]]=
In the United States, the wholesale cost per dose is less than 0.05 USD as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}}
=[[Cefalexin]]=
Generic drug versions are available under other trade names and are inexpensive.{{cite web|title=Cephalexin|url=https://www.drugs.com/monograph/cephalexin.html|publisher=The American Society of Health-System Pharmacists|accessdate=Apr 21, 2014}}{{cite book|last=Hanlon|first=Geoffrey|title=Essential Microbiology for Pharmacy and Pharmaceutical Science|date=2012|publisher=Wiley|location=Hoboken|isbn=9781118432433|page=140|url=https://books.google.com/books?id=P4Ucifn76PUC&pg=PT140|author2=Hodges, Norman}}
==Cost==
A seven day course of cephalexin costs a consumer about CA$25 in Canada in 2014.{{cite web |title=Price Comparison of Commonly Prescribed Pharmaceuticals in Alberta 2014 |url=https://www.acfp.ca/wp-content/uploads/2014/06/ACFPPricingDoc2014.pdf |accessdate=25 November 2019}} The wholesale cost of this amount is about CA$4.76 as of 2019.{{cite web |title=Online Formulary 2019 |url=http://formulary.drugplan.health.gov.sk.ca/SearchFormulary/BG/562880 |website=formulary.drugplan.health.gov.sk.ca |accessdate=25 November 2019}} In the United States this amount costs a consumer about US$20.96 as of 2019.{{cite web |title=Cephalexin Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/cephalexin |website=Drugs.com |accessdate=25 November 2019 |language=en}} In Australia a course of treatment costs at most AU$26.77 as of 2019.{{cite web |last1=Health |first1=Australian Government Department of |title=Pharmaceutical Benefits Scheme (PBS) {{!}} |url=http://www.pbs.gov.au/medicine/item/3119E |publisher=Australian Government Department of Health |accessdate=25 November 2019 |language=en}} The wholesale price in the developing world is about US$2.18 as of 2015.{{cite web |title=Search Results By Name {{!}} International Medical Products Price Guide |url=http://mshpriceguide.org/en/search-results-by-name-2/?searchYear=2015&searchString=Cefalexin&searchType=Name |website=The International Medical Products Price Guide |accessdate=25 November 2019}}
=[[Cefdinir]]=
In the United States the wholesale cost of ten days of medication is about US$9.40.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Cefixime]]=
The wholesale cost in the developing world is about US$0.26–2.09 per dose.{{cite web|title=Cefixime |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1131&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a course of treatment costs about $100–200 as of 2015.TarasconPP2015, page 86
=[[Cefotaxime]]=
The wholesale cost in the developing world is about US$0.23–4.70 per dose.{{cite web|title=Cefotaxime |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=122&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a course of treatment costs $100–200.TarasconPP2015, page 87
=[[Ceftazidime]]=
The wholesale cost in the developing world is about US$2.84–16.76 per day.{{cite web|title=Ceftazidime |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=125&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a course of treatment costs $100–200.TarasconPP2015, page 87
=[[Ceftriaxone]]=
In the developed world the wholesale cost per dose is about {{US$}}0.20 to {{US$}}2.32 as of 2014.{{cite web|title=Ceftriaxone|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=126&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=29 August 2016}} In the United States a course of treatment is typically less than {{US$}}25.TarasconPP2014, page 75
=[[Cefuroxime]]=
A week of treatment when taken by mouth in the United Kingdom costs the NHS about £18 as of 2019.BNF76, page 518 In the United States, the wholesale cost of this amount is about US$8.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 }}
=[[Celecoxib]]=
A month supply in the United Kingdom costs the NHS less than £2 as of 2019.BNF 76, pages 1097–1098 In the United States, the wholesale cost of this amount is about $US12.90.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Ceritinib]]=
== Cost ==
{{As of|2019}}, Zykadia is priced at {{US$|8,578}} per bottle of 70 capsules.{{cite web|title=Zykadia Prices|url=https://www.drugs.com/price-guide/zykadia|website=Drugs.com|accessdate=27 August 2019}}
=[[Cetirizine]]=
A month's supply in the United Kingdom costs the NHS about £0.70 as of 2019.BNF76, page 279 In the United States the wholesale cost of this amount is about US$2.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Chlorambucil]]=
The wholesale cost in the developing world is about US$111.87 per month.{{cite web|title=Chlorambucil|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=142&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom it costs the NHS about £145.84 per month.BNF69, page 580
=[[Chloramphenicol]]=
The wholesale cost in the developing world of an intravenous dose is about US$0.40–1.90.{{cite web|title=Chloramphenicol|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=145&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=26 August 2015}} In the United States an intravenous dose costs about $41.47.{{cite news|title=Chloramphenicol Prices, Coupons & Patient Assistance Programs - Drugs.com|url=https://www.drugs.com/price-guide/chloramphenicol|newspaper=Drugs.com}}
==Cost==
In many areas of the world an intravenous dose is about US$0.40–1.90. In the United States it costs about $3.60 per dose in oral tablet form at wholesale.
It is the cheapest treatment available for meningitis (US$5 per treatment course, compared to US$30 for ampicillin and US$15 for five days of ceftriaxone). It has the great advantage of requiring only a single injection, whereas ceftriaxone is traditionally given daily for five days. This recommendation may yet change, now that a single dose of ceftriaxone (cost US$3) has been shown to be equivalent to one dose of oily chloramphenicol.{{cite journal | title = Ceftriaxone as effective as long-acting chloramphenicol in short-course treatment of meningococcal meningitis during epidemics: a randomised non-inferiority study | journal = Lancet |author1=Nathan, N. |author2=Borel, T. |author3=Djibo, A. | year = 2005 | volume = 366 | issue = 9482 | pages = 308–313 | pmid = 16039333 | doi=10.1016/S0140-6736(05)66792-X |hdl=10144/23232 | url = https://fieldresearch.msf.org/bitstream/10144/23232/1/187_Ceftriaxone_as_effective_as_long-acting_-_Lancet_9482_2005.pdf }}
=[[Chlorhexidine]]=
The wholesale cost in the developing world is about US$2.20–4.10 per liter of 5% solution.{{cite web|title=Chlorhexidine Gluconate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=159&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom this amount costs the NHS about £4.80.BNF69, pages 568, 791, 839
=[[Chlorine-releasing compounds]]=
The wholesale cost in the developing world is about US$0.01–0.02 per 500 mg of the chloramine type.{{cite web|title=Chloramine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=143&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} They are used extensively in both the medical and the food industry.{{cite book|last1=Block|first1=Seymour Stanton|title=Disinfection, Sterilization, and Preservation|date=2001|publisher=Lippincott Williams & Wilkins|isbn=9780683307405|page=1082|url=https://books.google.ca/books?id=3f-kPJ17_TYC&pg=PA1082|language=en}}
==Disinfectants==
They are easy to use, widely available, and very cheap: as of 2014, the wholesale cost of chloramine-T in the developing world was US$0.01–0.02 per 500 mg tablet.
=[[Chloroquine]]=
The wholesale cost in the developing world is about {{US$}}0.04.{{cite web|title=Chloroquine (Base)|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=160&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=4 December 2015}} In the United States, it costs about {{US$}}5.30 per dose.{{cite web|title=Aralen Phosphate|url=https://www.drugs.com/monograph/chloroquine-phosphate.html|publisher=The American Society of Health-System Pharmacists|accessdate=Dec 2, 2015|df=dmy-all}}
=[[Chloroxylenol]]=
The wholesale cost in the developing world is about US$2.00–6.20 per litre of 5% solution.{{cite web|title=Chloroxylenol|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1214&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}{{dead link|date=September 2017 |bot=Level C |fix-attempted=yes }}
=[[Chlorpromazine]]=
The wholesale cost in the developing world is between US$0.02 and US$0.12 per day.{{cite web|title=Chlorpromazine HCL|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=173&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=1 December 2015|df=dmy-all}} In the United States the wholesale costs is about US$7.80 per day as of 2019.{{cite web |title=NADAC as of 2019-02-13 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-13/and3-kbbi |website=Centers for Medicare and Medicaid Services |accessdate=14 February 2019 |language=en}}
=[[Chlortalidone]]=
In the United States the wholesale cost is about US$13.50 a month.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Cholecalciferol]]=
==Cost==
In 2015, the wholesale cost in Costa Rica is about US$2.15 per 30 ml bottle of 10,000 IU/ml.{{cite web|title=Single Drug Information {{!}} International Medical Products Price Guide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1190&searchYear=2015|website=mshpriceguide.org|access-date=6 July 2017}} In the United States, human treatment costs less than US$25 per month.TarasconPP2015, page 231 In the UK, the cost to the NHS in 2018 for one month's treatment can be less than 3 GBP.{{cite web|last1=NICE|title=Colecalciferol|url=https://bnf.nice.org.uk/medicinal-forms/colecalciferol.html|access-date=3 May 2018}}
=[[Ciclosporin]]=
In 2016, the wholesale cost in the developing world was about {{US$}}106 a month.{{cite web|title=Ciclosporin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=895&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom, it cost the NHS about £121 per month.BNF69, page 632 The wholesale price in the United States was about US$173 per month.{{cite web|title=NADAC as of 2016-12-07 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services|accessdate=20 December 2016}}
=[[Cilostazol]]=
A month supply in the United Kingdom costs the NHS about 5 £ as of 2019.BNF76, pages 231–232 In the United States the wholesale cost of this amount is about US$6.20.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Ciprofloxacin]]=
It is available as a generic medication and is not very expensive.{{cite web|title=Ciprofloxacin Hydrochloride|url=https://www.drugs.com/monograph/ciprofloxacin-hydrochloride.html|publisher=The American Society of Health-System Pharmacists|access-date=23 August 2015|url-status=live|archive-url=https://web.archive.org/web/20150923232645/http://www.drugs.com/monograph/ciprofloxacin-hydrochloride.html|archive-date=23 September 2015|df=dmy-all}}TarasconPP2014, page 85 The wholesale cost in the developing world is between {{US$}}0.03 and {{US$}}0.13 a dose.{{cite web|title=Ciprofloxacin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=184&searchYear=2014|website=International Drug Price Indicator Guide|access-date=24 August 2015}} In the United States it is sold for about {{US$}}0.40 per dose.
==Cost==
=[[Cisplatin]]=
The wholesale cost in the developing world is about {{US$}}5.56 to {{US$}}7.98 per 50 mg vial.{{cite web |title=Cisplatin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1533&searchYear=2014|website=International Drug Price Indicator Guide |accessdate=8 December 2016}} In the United Kingdom this costs the NHS about £17.BNF69, page 605
=[[Clarithromycin]]=
The wholesale cost in the developing world is between US$0.13 and $0.79 per dose.{{cite web|title=Clarithromycin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1071&searchYear=2014|website=International Drug Price Indicator Guide|access-date=7 September 2015}} In the United States it is moderately expensive at $50–100 for a course of treatment.TarasconPP2015, page 92
== Cost ==
The wholesale cost is between US$0.13 and $0.79 per dose.{{cite web|title=Clarithromycin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1071&searchYear=2014|website=International Drug Price Indicator Guide|access-date=7 September 2015}} In the United States it is moderately expensive at $50–100 for a course of treatment.TarasconPP2015, page 92
=[[Clindamycin]]=
It is available as a generic medication and is not very expensive.TarasconPP2015 page 108 The wholesale cost in the developing world is about US$0.06–0.12 per pill.{{cite web|title=Clindamycin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1011&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=6 September 2015}} In the United States, it costs about $2.70 per dose.{{cite web |title=Clindamycin Hydrochloride |url=https://www.drugs.com/monograph/clindamycin-hydrochloride.html |publisher=The American Society of Health-System Pharmacists |accessdate=Sep 4, 2015 }}
==Cost==
It is available as a generic medication and is not very expensive.TarasconPP2015, page 108 The wholesale cost in the developing world is about US$0.06 to US$0.12 per pill.{{cite web |title=Clindamycin |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1011&searchYear=2014 |website=International Drug Price Indicator Guide |accessdate=6 September 2015 }} In the United States it costs about $2.70 per dose.
=[[Clobetasol propionate]]=
A month supply in the United Kingdom costs the NHS about 7.90 £ as of 2019.BNF76, page 1210 In the United States the wholesale cost of this amount is about 66 USD.{{cite web |title=NADAC as of 2019-02-27 |website=Centers for Medicare and Medicaid Services |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |accessdate=3 March 2019}}
=[[Clofazimine]]=
The wholesale cost in the developing world is about US$24 per month.{{cite web|title=Clofazimine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=192&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Clomifene]]=
The wholesale cost in the developing world is about 0.79 to 2.00 USD for a course of treatment.{{cite web|title=Clomifene|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=193&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States the wholesale cost of a course of treatment is 4.80 USD.{{cite web|title=NADAC as of 2016-12-21 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-21/6ebu-k7ew|website=Centers for Medicare and Medicaid Services|accessdate=26 December 2016}}
=[[Clomipramine]]=
The wholesale price in the developing world is between 0.11 and 0.21 per day as of 2014.{{cite web|title=Clomipramine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=195&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=3 December 2015}} In the United States the wholesale costs as of 2018 is about US$9 per day.{{cite web|title=NADAC as of 2018-02-07|url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-02-07/p5w9-7jxh|website=Centers for Medicare and Medicaid Services|accessdate=9 February 2018|language=en}}
=[[Clonazepam]]=
The wholesale cost in the developing world is between US$0.01 and US$0.07 per pill.{{cite web|title=Clonazepam|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=196&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=15 August 2015}} In the United States, the pills are about US$0.40 each.{{cite web |title=Clonazepam |url=https://www.drugs.com/monograph/clonazepam.html |publisher=The American Society of Health-System Pharmacists |access-date=August 15, 2015 }}
=[[Clonidine]]=
As of 2019 a month of medication costs the NHS about £8.BNF76, page 144 In the United States this amount costs about US$2.70 as of 2019.{{cite web |title=NADAC as of 2019-01-30 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-01-30/2c5s-3kst |website=Centers for Medicare and Medicaid Services |accessdate=3 February 2019 |language=en}}
=[[Clopidogrel]]=
The wholesale cost in the developing world is about US$0.77–31.59 per month.{{cite web|title=Clopidogrel Bisulfate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1486&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States, a month of treatment costs less than US$25.TarasconPP2015 page 147
=[[Clotrimazole]]=
The wholesale cost in the developing world as of 2014 is 0.20–0.86 USD per 20 gram tube of cream.{{cite web|title=Clotrimazole|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=198&searchYear=2014|website=International Drug Price Indicator Guide|access-date=28 October 2016}} In the United States a course of treatment typically costs less than US$25.TarasconP2016, page 176
==Society and culture==
The wholesale cost in the developing world as of 2014 is 0.20–0.86 USD per 20gm tube of cream. In the United States treatment typically costs less than US$25.TarasconPP2015, page 176
=[[Cloxacillin]]=
The wholesale cost in the developing world is about US$0.16 per day for the pills.{{cite web|title=Cloxacillin Sodium|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=204&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Clozapine]]=
The wholesale cost in the developing world is between US$0.05 and US$2.10 per day as of 2014.{{cite web|title=Clozapine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=894&searchYear=2014|website=International Drug Price Indicator Guide|access-date=2 December 2015}}
==Cost==
The wholesale cost in the developing world is between 0.05 and US$2.10 per day as of 2014. In the United Kingdom the injectable form is about 100 pounds per dose.{{Cite web |url= https://www.sussexpartnership.nhs.uk/sites/default/files/documents/im_cloz_-_trust_protocol_-v1_-_0417_-_final_0.pdf |title=Protocol for the use of intramuscular (IM) clozapine injection |last=Hewitt |first=Jed |last2=Haste |first2=Jules | name-list-style = vanc |date=April 2017 |website=Sussex Partnership NHS Foundation Trust |access-date=2019-03-15 }}
=[[Codeine]]=
The wholesale cost in the developing world is between {{US$|link=yes}}0.04 and {{US$}}0.29 per dose as of 2014.{{cite web|title=Codeine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=207&searchYear=2014|accessdate=10 January 2016 |publisher=International Drug Price Indicator Guide}} In the United States it costs about one dollar a dose.{{cite web|title=Codeine|url=https://www.drugs.com/monograph/codeine.html|publisher=The American Society of Health-System Pharmacists|accessdate=January 5, 2016|df=dmy-all}}
=[[Colchicine]]=
It is available as a generic medication in the United Kingdom where a month's supply costs the NHS about £7.27, as of 2019.BNF76, pages 1085–1086 In the United States, the wholesale cost of this amount is about US$252.20.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
==History==
URL Pharma raised the price from $0.09 per tablet to $4.85{{cite web | url=https://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/EnforcementActivitiesbyFDA/SelectedEnforcementActionsonUnapprovedDrugs/ucm227961.htm | title=Questions and Answers for Patients and Healthcare Providers Regarding Single-ingredient Oral Colchicine Products | work=fda.gov}}
=[[Colistin]]=
In the United Kingdom it costs the NHS about £5.40 per day for the injectable form as of 2018.BNF76, page 547 In the United States this amount costs about US$47 as of 2019.{{cite web |title=Colistimethate Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/colistimethate |website=Drugs.com |accessdate=11 November 2019 |language=en}}
=[[Condom]]=
The wholesale cost in the developing world is about 0.03 to US$0.08 each.{{cite web|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=209&searchYear=2015|title=Condoms (Lubricated)|website=International Medical Products Price Guide|publisher=Management Sciences For Health, Inc.|accessdate=2 August 2017}} In the United States condoms usually cost less than US$1.00.{{cite book|last1=Shoupe|first1=Donna|title=Contraception|date=2011|publisher=John Wiley & Sons|isbn=9781444342635|page=15|url=https://books.google.com/books?id=ksjJcx1CeKcC&lpg=PA15&pg=PA15|language=en}}
=[[Copper IUDs]]=
The wholesale cost in the developing world is about US$0.37–3.00 per IUD.{{cite web|title=Iud (Copper)|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=450&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom they cost the NHS about £10 GBP.BNF69, pages 557–559 In the United States they cost around $750.{{cite book|last1=Zieman|first1=Mimi|title=Managing Contraception 2012–2014|publisher=Managing Contraception|isbn=978-1-4675-3640-0|page=Chapter 27|url=https://books.google.com/books?id=SdUDdQtGMGoC&pg=PT378|language=en|year=2012}}
=[[Cyanocobalamin]]=
In the United Kingdom it costs the NHS about 2.90 £ per injection as of 2019.BNF76, pages 993–994 In the United States the wholesale cost of this amount was about US$0.77 in 2019.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019}}
=[[Cyclobenzaprine]]=
n the United States, the wholesale cost per dose is less than US$0.05 as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |access-date=22 December 2018 |language=en}}
=[[Cyclophosphamide]]=
The wholesale cost in the developing world is about US$3.65–14.30 per 1 g vial.{{cite web|title=Cyclophosphamide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=996&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United Kingdom this dose costs the NHS about 17.06 pounds.BNF69, page 580 In the United States this dose by mouth is about $19.56.{{cite web|title=NADAC as of 2016-12-07 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services|access-date=20 December 2016}}
=[[Cycloserine]]=
The wholesale cost in the developing world is about {{nowrap|{{Currency|29|USD}}.70–51.30}} per month.{{cite web|title=Cycloserine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=221&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In 2015, the cost in the United States was increased to {{Currency|3,150|USD|linked=no}} a month and then decreased to {{Currency|1,050|USD|linked=no}} per month.{{cite news|author1=Andrew Pollack|title=Big Price Increase for Tuberculosis Drug Is Rescinded|url=https://www.nytimes.com/2015/09/22/business/big-price-increase-for-tb-drug-is-rescinded.html?_r=0|accessdate=24 September 2015|work=NYT|date=21 September 2015}}
==Economics==
In the U.S., the price of cycloserine increased from $500 for 30 pills to $10,800 in 2015 after the Chao Center for Industrial Pharmacy and Contract Manufacturing changed ownership to Rodelis Therapeutics in August 2015.{{cite news|author1=ANDREW POLLACK|title=Drug Goes From $13.50 a Tablet to $750, Overnight|url=https://www.nytimes.com/2015/09/21/business/a-huge-overnight-increase-in-a-drugs-price-raises-protests.html?ref=health&_r=0|accessdate=21 September 2015|date=20 September 2015}}
The price increase was rescinded after the previous owner, the Purdue University Research Foundation, which retained "oversight of the manufacturing operation" intervened and Rodelis returned the drug to an NGO of Purdue University. The foundation now will charge $1,050 for 30 capsules, twice what it charged before".
=[[Cytarabine]]=
The wholesale cost in the developing world is about {{US$}}4.27 to US$5.70 per 500 mg vial.{{cite web|title=Cytarabine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1215&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} This dose in the United Kingdom costs the NHS about {{GBP}}50.00 while the liposomal form is {{GBP}}1,223.75 per 50 mg vial.BNF69, page 589
=[[Dabigatran]]=
A month supply in the United Kingdom costs the NHS about £51 as of 2019.BNF76, pages 135–137 In the United States the wholesale cost of this amount is< about 416 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 }}
==History==
According to a BBC article in 2008, Dabigatran was expected to cost the NHS £4.20 per day, which was similar to several other anticoagulants.{{cite news | title= Clot drug 'could save thousands' | date=2008-04-20 | url=http://news.bbc.co.uk/1/hi/health/7354818.stm | work=BBC News Online | accessdate=2008-04-21 }}
=[[Dacarbazine]]=
The wholesale cost in the developing world is about US$7.45–18.24 per 200 mg vial.{{cite web|title=Dacarbazine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=997&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom this dose costs the NHS about 7.50 pounds.BNF69, page 600
=[[Dactinomycin]]=
The wholesale cost in the developing world is about US$24.73 per 500 mcg vial.{{cite web|title=Dactinomycin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=224&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Daunorubicin]]=
The wholesale cost in the developing world is about 5.79 to 37.18 USD for a 20 mg vial.{{cite web|title=Daunorubicin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1298&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} This amount in the United Kingdom costs the NHS about 55.00 pounds.BNF69, pages 581–583
=[[Deferoxamine]]=
The wholesale cost in the developing world is about US$6.76 to $13.52 per dose.{{cite web|title=Deferoxamine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=229&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a course of treatment costs more than $200.TarasconPP2014, page 470
=[[Desiccated thyroid extract]]=
In the United States the wholesale cost for a month of medication is about US$15.30.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Desonide]]=
== Cost ==
Desonide topical cream and ointment is sold in 15g and 60g tubes of %0.05 gel, and desonide lotion is sold in 2 fluid ounce bottles.Drugs.com: [https://www.drugs.com/price-guide/desonide-topical Topical Desonide] A single 60g tube or one (1) bottle of lotion costs as much as $200.
=[[Desvenlafaxine]]=
In the United States the wholesale cost is about 25.20 USD per month.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Dexlansoprazole]]=
In the United States the wholesale cost for a month is about US$270.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 |language=en}} In Canada this amount costs about 71.50 CAD in 2016 making it the most expensive PPI available at the time.{{cite web|title=[99] Comparative effectiveness of proton pump inhibitors {{!}} Therapeutics Initiative|url=http://www.ti.ubc.ca/2016/06/28/99-comparative-effectiveness-proton-pump-inhibitors/|access-date=14 July 2016|date=28 June 2016}}
=[[Dexmethylphenidate]]=
The wholesale cost of a month supply in the United States is about US$8.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Dextran 70]]=
The wholesale cost in the developing world is about US$4.10–5.25 per 500 ml.{{cite web|title=Dextran 70 6% in Sod. chloride 0.9%|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=240&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom this dose costs the NHS about 57.00 pounds.BNF69, page 686 In the United States it costs about $25–50 per dose.TarasconPP2015, page 167
=[[Diatrizoate]]=
As of 2016, the wholesale cost in the developing world is about US$5.49 per 20 ml vial.{{cite web|title=Amidotrizoate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1001&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a dose costs less than US$25.TarasconPP2015, page 171
=[[Diazepam]]=
The wholesale cost in the developing world is about US$0.01 per dose {{as of|2014|lc=y}}.{{cite web|title=Diazepam|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=250&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=2 December 2015}} In the United States, it is about US$0.40 per dose.{{cite web|title=Diazepam|url=https://www.drugs.com/monograph/diazepam.html|publisher=The American Society of Health-System Pharmacists|accessdate=2015-06-05}}
=[[Diazoxide]]=
In the United States as of 2019 it costs about US$1500 per month.{{cite web |title=Proglycem Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/proglycem |website=Drugs.com |accessdate=11 October 2019 |language=en|quote=Typical dose is 3mg/kg * 70 kg * 30 days = 6,300 mg at 11.58 per 50 mg }} In the United Kingdom this amount costs the NHS about £59.BNF76, page 708
=[[Diclofenac]]=
The wholesale cost in the developing world is generally less than US$2 per month as of 2015.{{cite web |title=Diclofenac Sodium |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=256&searchYear=2015 |website=International Medical Products Price Guide |accessdate=4 December 2019}} In the United States the wholesale cost of this amount is typically less than US$9 as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |access-date=22 December 2018 |language=en}}
==Cost==
In the United States the NADAC per dose is less than US$0.15 as of 2018 for 50 mg and 75 mg tablets.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |access-date=22 December 2018 |language=en}} The average wholesale cost in the United States in 2019 is about US$50 to $US100 per month at a typical dose.TarasonPP2019, page 6
=[[Dicycloverine]]=
In the United Kingdom the NHS pays about 1.84 £ per dose as of 2019.BNF76, page 759 In the United States the wholesale cost of this amount is about 0.15 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Diethylcarbamazine]]=
=[[Digoxin]]=
The wholesale cost in the developing world is about US$0.21 to $6.60 a month.{{cite web |title=Digoxin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=266&searchYear=2014 |website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United States it generally costs less than $25 per month, as of 2015.TarasconPP2015
=[[Diltiazem]]=
In the United States the wholesale cost per day of the by mouth formulation is less than 0.70 USD as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |access-date=22 December 2018 |language=en}}
=[[Diphenhydramine]]=
The wholesale price in the developing world {{Asof|2014|lc=y}} is about {{currency|.01|USD}} per dose.{{cite web|title=Diphenhydramine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=273&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=28 September 2016}} In the United States, it costs less than {{currency|25|USD}} for a typical month’s supply.TarasconPP2015, page 240
=[[Diphtheria vaccine]]=
The wholesale price in the developing world of a version that contains tetanus toxoid is between 0.12 and 0.99 USD per dose as of 2014.{{cite web|title=Vaccine, Diphtheria-Tetanus|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=790&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=6 December 2015}} In the United States it is less than 25 USD.TarasconPP2015, page 313
=[[Docetaxel]]=
The wholesale cost in the developing world is about {{US$}}15.53 to {{US$}}87.37 per 80 mg vial.{{cite web|title=Docetaxel|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1454&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} This dose in the United Kingdom costs the NHS about £454.53.BNF69, page 622
==Costs==
In the UK (in 2009) The cost of six cycles (18 weeks) of docetaxel at a dose of 75 mg/m2 IV every 21 days is £5,262 (based on an average body surface area 1.75 m2).http://www.haps.bham.ac.uk/publichealth/horizon/outputs/documents/2009/jan-apr/Cabazitaxel.pdf ref : National Institute for Health and Clinical Excellence. Prostate cancer (hormone-refractory) — docetaxel: analysis of cost impact London: NICE; September 2006. {{cite web |url=http://www.nice.org.uk/guidance/index.jsp?action=download&o=33354 |title=Archived copy |accessdate=2010-06-10 }}
=[[Docosanol]]=
When introduced in Canada in 2005 it sold for CA$6.12 per gram of 10% cream.{{cite web |title=Report on New Patented Drugs - Abreva |url=http://www.pmprb-cepmb.gc.ca/view.asp?ccid=574 |website=pmprb-cepmb.gc.ca |accessdate=25 November 2019 |language=en |date=13 May 2014}} In the United States in 2019 this amount cost US$10.36.{{cite web |title=Docosanol topical Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/docosanol-topical |website=Drugs.com |accessdate=25 November 2019 |language=en}}
=[[Donepezil]]=
In the United Kingdom a typical months supply costs the NHS about £8.44 as of 2019.BNF76, page 300 The wholesale cost of this amount in the United States is about US$1.38. {{cite web |title=NADAC as of 2019-01-30 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-01-30/2c5s-3kst |website=Centers for Medicare and Medicaid Services |accessdate=4 February 2019 |language=en}}
=[[Dopamine (medication)]]=
The wholesale cost in the developing world of a container of 400 mg is between $0.28 and $0.60 (USD) as of 2014.{{cite web|title=Dopamine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=280&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=5 December 2015}}
=[[Dorzolamide]]=
A 5 milliliter bottle in the United Kingdom costs the NHS less than 2 £ as of 2019.BNF76, page 1148 In the United States the wholesale cost of this amount is about US$7.10.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Dorzolamide/timolol]]=
A 5 milliliter bottle in the United Kingdom costs the NHS about 1.50 £ as of 2019.BNF 76, page 1149 In the United States the wholesale cost of this amount is about US$8.30.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
== Cost ==
The brand name Cosopt currently costs upwards of $200 after discounts{{Cite web|url=https://www.goodrx.com/cosopt|title=Prices and Coupons for Cosopt|access-date=2017-10-29}} while the generic formulation costs around $70 cash.{{Cite web|url=https://www.goodrx.com/cosopt|title=Prices and Coupons for Cosopt|website=www.goodrx.com|access-date=2017-10-29}} The more recent preservative free formulation can be purchased for less than the original brand name formulation at around $160{{Cite web|url=https://www.goodrx.com/cosopt-pf|title=Prices and Coupons for Cosopt PF|website=www.goodrx.com|access-date=2017-10-29}}
=[[Doxazosin]]=
A month supply in the United Kingdom costs the NHS about 0.50 £ as of 2019.BNF 76, page 765 In the United States the wholesale cost of this amount is about US$5.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Doxepin]]=
A month supply in the United Kingdom costs the NHS at least 100 £ as of 2019.BNF 76, page 372 In the United States the wholesale cost of this amount is about US$23.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Doxorubicin]]=
The wholesale cost in the developing world is about US$3.88–32.79 per 50 mg vial.{{cite web|title=Doxorubicin HCL|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=282&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom this amount costs the NHS about £100.12.{{Cite web|url=https://www.evidence.nhs.uk/formulary/bnf/current/8-malignant-disease-and-immunosuppression/81-cytotoxic-drugs/812-anthracyclines-and-other-cytotoxic-antibiotics/doxorubicin-hydrochloride/doxorubicin|title=Doxorubicin British National Formulary|website=BNF|access-date=6 March 2017}}BNF69, page 583
=[[Doxycycline]]=
The wholesale cost in the developing world is between US$0.01 and US$0.04 per pill.{{cite web|title=Doxycycline|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=283&searchYear=2015|website=International Medical Products Price Guide|accessdate=16 January 2018}} In the United States, ten days of treatment has a wholesale costs of about US$3.40 as of 2019.{{cite web |title=NADAC as of 2019-09-11 {{!}} Data.Medicaid.gov |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-09-11/xh57-kaa3 |website=Centers for Medicare and Medicaid Services |accessdate=10 September 2019 |language=en}} However, in 2014, due to supply issues, it was being sold for as much as US$60.00–200.00 for that amount.{{cite web|title=Doxycycline calcium|url=https://www.drugs.com/monograph/doxycycline-calcium.html|publisher=The American Society of Health-System Pharmacists|accessdate=Aug 18, 2015|df=dmy-all}}{{cite news|title=Officials Question the Rising Costs of Generic Drugs|url=https://www.nytimes.com/2014/10/08/business/officials-question-the-rising-costs-of-generic-drugs.html|accessdate=22 September 2015|work=New York Times|date=Oct 7, 2014|df=dmy-all}}
==History==
The market price for doxycycline dramatically increased in the United States in 2013 and early 2014 (from $20 to over $1800 for a bottle of 500 tablets),[http://www.wsmv.com/story/21616095/sudden-increase-in-cost-of-common-drug-concerns-many Sudden increase in cost of common drug concerns many] {{webarchive|url=https://web.archive.org/web/20141231084623/http://www.wsmv.com/story/21616095/sudden-increase-in-cost-of-common-drug-concerns-many |date=31 December 2014 }}, WSMV-TV, 12 March 2013 (updated 26 March 2013).Rosenthal, Elisabeth, [https://www.nytimes.com/2014/10/08/business/officials-question-the-rising-costs-of-generic-drugs.html Officials Question the Rising Costs of Generic Drugs] {{webarchive|url=https://web.archive.org/web/20170223043227/https://www.nytimes.com/2014/10/08/business/officials-question-the-rising-costs-of-generic-drugs.html |date=23 February 2017 }}, The New York Times, 7 October 2014.Eric Palmer for FiercePharmaManufacturing. 13 March 2014 [http://www.fiercepharmamanufacturing.com/story/hikma-hits-jackpot-doxycycline-shortage/2014-03-13 Hikma hits the jackpot with doxycycline shortage] {{webarchive|url=https://web.archive.org/web/20150101012858/http://www.fiercepharmamanufacturing.com/story/hikma-hits-jackpot-doxycycline-shortage/2014-03-13 |date=1 January 2015 }} before decreasing again.{{cite web|url=http://www.costco.com/Pharmacy/drug-results-details-price?storeId=10301&catalogId=10051&langId=-1&searchKeyword=Doxycycline&drugId=212&drugName=Doxycycline&drugSearch=headerDrugSearch&isPharmacy=true&encodedDrugName=Doxycycline|title=Costco Drug Information|date=|website=|accessdate=July 31, 2016|df=dmy-all}}{{cite web|url=http://www.goodrx.com/doxycycline-hyclate?drug-name=doxycycline+hyclate|title=Doxycycline Hyclate Prices and Doxycycline Hyclate Coupons|format=|work=GoodRx|accessdate=July 31, 2016|date=|df=dmy-all}}
==Society and culture==
Doxycycline is available as a generic medicine and is generally inexpensive.TarasconPP2011, page 79 The wholesale cost is between US$0.01 and $0.04 per pill.
=[[Duloxetine]]=
In the United States the wholesale cost per dose is about US$0.20 as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}} In 2016 it was the 48th most prescribed medication in the United States with more than 15 million prescriptions.{{cite web |title=The Top 300 of 2019 |url=https://clincalc.com/DrugStats/Top300Drugs.aspx |website=clincalc.com |accessdate=22 December 2018}}
=[[Dutasteride]]=
A month supply in the United Kingdom costs the NHS about £12 as of 2019.BNF76, page 769 In the United States, the wholesale cost of this amount is about $6.66.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Efavirenz]]=
The wholesale cost in the developing world is about {{USD|3.27 to 9.15}} per month.{{cite web|title=Efavirenz|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1023&searchYear=2014|website=International Drug Price Indicator Guide|access-date=28 November 2016}} As of 2015 the cost for a typical month of medication in the United States is more than {{USD|200}}.TarasconPP2015, page 62
==Society and culture==
A one-month supply of 600 mg tablets costs approximately US$1,010 in July 2016.{{Cite web|url=https://aidsinfo.nih.gov/guidelines/html/1/adult-and-adolescent-arv-guidelines/459/cost-considerations-and-antiretroviral-therapy|title=Cost Considerations and Antiretroviral Therapy {{!}} Adult and Adolescent ARV Guidelines {{!}} AIDSinfo|website=AIDSinfo|access-date=2016-11-16}} In 2007, Merck provided Efavirenz in certain developing countries and countries largely affected by HIV for about US$0.65 per day.{{cite news|url=https://www.drugs.com/news/merck-amp-co-inc-again-reduces-price-stocrin-efavirenz-patients-least-developed-countries-countries-5302.html|title=Merck & Co., Inc., Again Reduces Price of Stocrin (Efavirenz) for Patients in Least Developed Countries and Countries Hardest Hit by Epidemic|work=Drugs.com MedNews}} Some emerging countries have opted to purchase Indian generics.[http://www.indiadaily.com/editorial/16665.asp IndiaDaily - A new trend in emerging nations - Brazil opts for Indian generic drug ignoring US pharmaceutical giant Merck's patent on AIDS drug Efavirenz] {{webarchive|url=https://web.archive.org/web/20080219112307/http://www.indiadaily.com/editorial/16665.asp |date=2008-02-19 }}
In Thailand, a one month supply of efavirenz + Truvada, as of June 2012, cost 2,900 baht ({{USD|90}}), and there is a social program for patients who cannot afford the medication. {{Asof|2018}} Thailand will produce efavirenz domestically. Its Government Pharmaceutical Organization product costs 180 baht per bottle of thirty 600 mg tablets. The imported version in Thailand retails for more than 1,000 baht per bottle. GPO will devote 2.5 percent of its manufacturing capacity to make 42 million efavirenz pills in 2018, allowing it to serve export markets as well as domestic. The Philippines alone will order about 300,000 bottles of efavirenz for 51 million baht.{{cite news |last1=Wipatayotin |first1=Apinya |title=Thailand gets nod to make HIV/Aids drug |url=https://www.bangkokpost.com/news/general/1569426/thailand-gets-nod-to-make-hiv-aids-drug |access-date=3 November 2018 |work=Bangkok Post |date=3 November 2018}}
=[[Efavirenz/emtricitabine/tenofovir]]=
The wholesale cost in the developing world is about US$10.71–14.19 per month as of 2014.{{cite web|title=Efavirenz + Emtricitabine + Tenofovir Df|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1269&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=28 November 2016}} The wholesale cost in the United States is about $2308.20 a month as of 2016, while in the United Kingdom it costs the NHS {{GB£}}532.87 per month as of 2015.{{cite web|title=NADAC as of 2016-12-07 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services|accessdate=12 December 2016}}BNF69, page 423
==History==
An equivalent two pill regimen is available in developing countries at a price of about US$1.00 per day, as Gilead Sciences has licensed the patents covering emtricitabine/tenofovir to the Medicines Patent Pool{{cite web|url=http://www.unitaid.eu/en/resources/news/348-medicines-patent-pool-signs-licence-agreement-with-gilead-to-increase-access-to-hivaids-medicines|title=Medicines Patent Pool Signs Licence Agreement with Gilead to Increase Access to HIV/AIDS Medicines}} and Merck and Co makes efavirenz available in developing countries at a reduced price.{{cite web|url=http://www.aidsmap.com/Merck-cuts-price-of-efavirenz-for-developing-countries-again/page/1426314/|title=HIV & AIDS Information :: Merck cuts price of efavirenz for developing countries again}}
==Cost==
The wholesale cost in the developing world is about US$10.71–14.19 per month as of 2014.
=[[Empagliflozin]]=
A month supply in the United Kingdom costs the NHS about £36.59 as of 2019.BNF76, page 691 In the United States the wholesale cost of this amount is about US$442.{{cite web |title=NADAC |date=2019-02-27 |df=dmy-all |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 }}
=[[Emtricitabine/tenofovir]]=
The 2015 wholesale cost in the developing world is about {{US$}}6.06 to {{US$}}7.44 per month.{{cite web|title = Tenofovir DF+Emtricitabine|url = http://mshpriceguide.org/en/single-drug-information/?DMFId=1274&searchYear=2014|website = International Drug Price Indicator Guide|accessdate = 2015-08-01|publisher = Management Sciences for Health and World Health Organization|year = 2014}} In the United States, as of 2019, the wholesale cost is about US$1,710.00 per month.{{cite web |title=NADAC as of 2019-11-13 {{!}} Data.Medicaid.gov |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-11-13/sbun-j698 |website=Centers for Medicare and Medicaid Services |accessdate=15 November 2019 |language=en}} In Australia, this amount costs about US$8.{{cite web |title=AOC asks pharma CEO why $2,000 HIV drug costs just $8 in Australia |url=https://www.independent.co.uk/news/world/americas/us-politics/aoc-hiv-drug-cost-us-australia-ceo-gilead-video-a8919316.html?fbclid=IwAR3zDFEnIM7M4xoT91k-Jf638bt5gArLS-XQx3NbHRbGrWeHwAjAc7DYWeE |website=The Independent |accessdate=15 November 2019 |language=en |date=17 May 2019}}
== Cost ==
{{As of|2014}}, the median cost per tablet, in Namibia and South Africa, was {{US$|0.20}}. In Canada, emtricitabine/tenofovir cost between $800 - $1,100 per month in 2016.{{cite web|url=http://www.actoronto.ca/home.nsf/pages/act.docs.2293|title=Pre-Exposure Prophylaxis (PrEP) as a form of HIV prevention|website=AIDS Committee of Toronto |access-date=2016-11-01}} Generic emtricitabine/tenofovir was approved by Health Canada in August 2017, with a wholesale cost of $400 per month.{{cite web|url=http://www.catie.ca/en/catienews/2017-07-27/generic-tenofovir-ftc-coming-canada|title=Generic tenofovir + FTC coming to Canada|website=www.catie.ca|access-date=30 August 2017}} The cost for emtricitabine/tenofovir PrEP in Ontario, Canada dropped significantly after approval in September 2017.{{cite web | title=PrEP in Ontario | website=AIDS Committee of Toronto | date=28 September 2017 | url=http://www.actoronto.org/health-information/sexual-health/prep-info/prepontario.pdf | access-date=31 October 2019}}
In the United States, {{as of|2016|lc=yes}}, the wholesale cost is about {{US$|1415.00}} per month.{{cite web|title=NADAC as of 2016-12-07 |url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services (CMS)|accessdate=12 December 2016}} This increased in 2019 to about US$1,710.00 per month. The price of emtricitabine/tenofovir in the United States has been criticized by activists, who argued in a 2018 The New York Times opinion piece that the high cost keeps the drug out of reach for millions, thus harming efforts to reduce new HIV infections.{{cite news | first1=James | last1=Krellenstein | first2=Aaron | last2=Lord | first3=Peter | last3=Staley |title=Why Don't More Americans Use PrEP? |url=https://www.nytimes.com/2018/07/16/opinion/prep-hiv-aids-drug.html |accessdate=30 July 2018 |work=The New York Times |date=16 July 2018 | name-list-style=vanc }} The Gilead CEO defended the high price at a U.S. House of Representatives committee hearing.{{cite web | title=Under fire for Truvada US pricing at House hearing, Gilead chief O'Day touts R&D costs, asserts governments patents are void | first=Natalie | last=Grover | website=Endpoints News | date=17 May 2019 | url=https://endpts.com/under-fire-for-truvada-us-pricing-at-house-hearing-gilead-chief-oday-touts-rd-costs-asserts-governments-patents-are-void/ | access-date=31 October 2019 | name-list-style=vanc }} Generic emtricitabine/tenofovir was approved in the United States in 2018,{{cite web | title=2018 First Generic Drug Approvals | website=U.S. Food and Drug Administration (FDA) | date=2019-11-01 | url=https://www.fda.gov/drugs/first-generic-drug-approvals/2018-first-generic-drug-approvals | access-date=29 October 2019}}{{PD-notice}} and it is scheduled to be released by Teva in September 2020.{{cite web | title=Gilead Sciences Form 10-Q Quarterly Filing | website=Gilead Sciences | date=31 March 2019 | url=http://investors.gilead.com/node/35611/html | access-date=29 October 2019}}
=[[Enalapril]]=
The wholesale cost in the developing world is about US$0.08 to 0.80 per month.{{cite web|title=Enalapril|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=287&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United States, it costs about $25 to $50 per month.TarasconPP2015, page 120
=[[Enoxaparin sodium]]=
The wholesale cost in the developing world is about US$1.90–10.80 per day.{{cite web|title=Enoxaparin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=291&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States the wholesale cost is about $14.13 per day as of 2016.{{cite web|title=NADAC as of 2016-12-07 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services|accessdate=15 December 2016}}
=[[Ephedrine]]=
The wholesale cost in the developing world is about US$0.69–1.35 per dose.{{cite web|title=Ephedrine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=293&searchYear=2014|website=International drug price indicator guide|access-date= 1 January 2016}} In the United States it is not very expensive.TarasconPP2015, page 162
=[[Epinephrine (medication)]]=
The wholesale cost in the developing world is between US$0.10 and US$0.95 a vial.{{cite web |title=Epinephrine |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=298&searchYear=2014 |website=International Drug Price Indicator Guide |accessdate=15 August 2015 }} In the United States, the cost of the most commonly used autoinjector for anaphylaxis was about US$600 for two in 2016, while a generic version was about US$140 for two.{{cite web|url=http://www.consumerreports.org/drugs/can-you-get-a-cheaper-epipen/|title=Can You Get A Cheaper EpiPen?|author=Ginger Skinner|date=August 11, 2016|publisher=Consumer Reports}} In Canada the wholesale cost of two cost is CA$190 as of 2019.{{cite web |title=[119] Epinephrine autoinjectors available in Canada |url=https://www.ti.ubc.ca/2019/05/23/119-epinephrine-autoinjectors-available-in-canada/ |website=Therapeutics Initiative |accessdate=26 May 2019 |language=en-CA |date=23 May 2019}}
==Cost==
The wholesale cost of epinephrine in the developing world is between US$0.10 and US$0.95 a vial. In the United States, the cost of the most commonly used autoinjector for anaphylaxis was about US$600 for two in 2016, while a generic version was about US$140 for two. In Canada the wholesale cost of two cost is CA$190 as of 2019.
=[[Ergometrine]]=
The wholesale cost in the developing world is between US$0.12 and US$0.41 for an injectable dose and US$0.01 for a pill as of 2014.{{cite web|title=Ergometrine Maleate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=305&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=25 December 2015}}{{cite web|title=Ergometrine Maleate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=304&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=25 December 2015}} In the United States it is about US$1.75 per dose.{{cite web|title=Ergonovine Maleate|url=https://www.drugs.com/monograph/ergonovine-maleate.html|publisher=The American Society of Health-System Pharmacists|accessdate=1 December 2015}}
=[[Erlotinib]]=
In the United States, {{as of|2019|lc=yes}}, it costs about US$8,832 per month.{{cite web |title=Tarceva Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/tarceva |website=Drugs.com }} In the United Kingdom this amount costs the NHS about £1,631.53 per month.BNF76, page 950
==Price==
In the United States, {{as of|2019|lc=yes}}, it costs about US$8,832 per month. In the United Kingdom this amount costs the NHS about £1,631.53 per month.
=[[Erythromycin]]=
It is available as a generic medication and is not very expensive.TarasconPP2013, page 72 The wholesale price in the developing world is between 0.03 and 0.06 USD per tablet.{{cite web|title=Erythromycin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=311&searchYear=2014 | website = International Drug Price Indicator Guide|access-date=23 August 2015}}
== Cost ==
It is available as a generic medication and was inexpensive for many years. The wholesale price was between 0.03 and 0.06 USD per pill.
In the United States in 2014 the price increased to seven dollars per tablet.Stahl, Stephanie (September 26, 2014) [http://philadelphia.cbslocal.com/2014/09/26/health-generic-drugs-prices-increasing/ Health: Generic Drugs Prices Increasing] {{webarchive|url=https://web.archive.org/web/20160409212651/http://philadelphia.cbslocal.com/2014/09/26/health-generic-drugs-prices-increasing/ |date=2016-04-09 }} CBS Philadelphia. Retrieved March 24, 2016.
The price of Erythromycin rose three times between 2010 and 2015, from 24 cents per tablet in 2010 to $8.96 in 2015.{{cite web |title=Some Generic Drugs See Huge Price Increases|url=https://www.medscape.com/viewarticle/868812 |website=www.medscape.com |access-date=29 June 2018}} In 2017, a Kaiser Health News study found that the per-unit cost of dozens of generics doubled or even tripled from 2015 to 2016, increasing spending by the Medicaid program. Due to price increases by drug manufacturers, Medicaid paid on average $2,685,330 more for Erythromycin in 2016 compared to 2015 (not including rebates).{{cite web |title=Climbing cost of decades-old drugs threatens to break Medicaid bank |url=http://www.philly.com/philly/health/health-cents/climbing-cost-of-decades-old-drugs-threatens-to-break-medicaid-bank-20170814.html |website=Philly.com |access-date=29 June 2018}} By 2018, generic drug prices had climbed another 5% on average.{{cite web |title=Are Drugs Really Getting More Expensive? Yes. |url=https://www.goodrx.com/blog/are-drugs-getting-more-expensive/ |website=The GoodRx Prescription Savings Blog |access-date=29 June 2018 |date=27 February 2018}}
=[[Erythropoiesis-stimulating agent]]=
The wholesale cost of one version in the developing world, as of 2015, is about 3.80 USD per 2000 unit vial.{{cite web|title=Single Drug Information|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=301&searchYear=2015&classifDetailsId=37|website=International Medical Products Price Guide|accessdate=10 December 2017}} In the United Kingdom this amount costs about 10 pounds as of 2015.BNF69, pages 666–671
=[[Escitalopram]]=
In the United States the wholesale cost is about $2.04 per month {{as of|2017|lc=y}}.{{cite web|title=NADAC as of 2017-12-27|url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2017-12-27/aie5-m2gf|website=Centers for Medicare and Medicaid Services|access-date=31 December 2017|language=en}} In the United Kingdom, {{as of|2018|lc=y}}, non-proprietary escitalopram is around 1 / 20th as costly as the proprietary version.{{cite web|title=Escitalopram Medicinal Forms|url=https://bnf.nice.org.uk/medicinal-forms/escitalopram.html|website=BNF|access-date=27 September 2018|date=2018}} Link restricted to the UK.
=[[Esomeprazole]]=
A month supply in the United Kingdom costs the NHS about £3 as of 2019.BNF76, page 78 In the United States the wholesale cost of this amount is about 10 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 }}
=[[Eszopiclone]]=
In the United States the wholesale cost is about 0.20 USD per dose.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Ethambutol]]=
The wholesale cost in the developing world is about US$2.58–4.73 per month.{{cite web|title=Ethambutol|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=317&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States it costs US$100–200 per month.TarasconPP2015, page 48
=[[Ethambutol/isoniazid]]=
The wholesale cost in the developing world is about 1.47 to 1.99 USD a month.{{cite web|title=Ethambutol + Isoniazid|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=321&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Ethambutol/isoniazid/rifampicin]]=
The wholesale cost in the developing world is about 6.74 to 16.13 USD a month.{{cite web|title=Rifampicin + Isoniazid + Ethambutol|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1100&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Ethinylestradiol/etonogestrel]]=
In the United States the wholesale cost of this amount is about US$468.78.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Ethionamide]]=
The wholesale cost in the developing world is about $5.94 to $24.12 USD per month.{{cite web|title=Ethionamide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=337&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Ethosuximide]]=
The wholesale cost in the developing world is about US$27.77 per month as of 2014.{{cite web|title=Ethosuximide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=338&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United States the wholesale cost of this amount is about US$95.97 per month.{{cite web |title=NADAC as of 2019-11-27 {{!}} Data.Medicaid.gov |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-11-27/qjsh-shte |website=Centers for Medicare and Medicaid Services |accessdate=3 December 2019 |language=en}}
=[[Etonogestrel birth control implant]]=
The wholesale cost in the developing world is about 8.93 to 13.29 USD.{{cite web|title=Etonogestrel|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1263&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United Kingdom the device costs the NHS about 83.43 pounds.BNF76, page 791 The cost in the United States is about 625.00 USD.{{cite book|last1=Wipf|first1=Joyce| name-list-style = vanc |title=Women's Health, An Issue of Medical Clinics of North America|date=2015|publisher=Elsevier Health Sciences|isbn=9780323376082|pages=507–509|url=https://books.google.com/books?id=fJzuCQAAQBAJ&pg=PA507|url-status=live|archive-url=https://web.archive.org/web/20170924000754/https://books.google.com/books?id=fJzuCQAAQBAJ&pg=PA507|archive-date=2017-09-24}}
=[[Etoposide]]=
The wholesale cost in the developing world is about US$3.24 to US$5.18 per 100 mg vial.{{cite web|title=Etoposide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=340&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom this costs the NHS about £12.15 as of 2015.BNF69, page 593
=[[Exenatide]]=
A month supply in the United Kingdom costs the NHS about £82 for the daily injectable and £73 for the weekly injectable version as of 2019.BNF76, pages 684–685 In the United States the wholesale cost of this amount is about {{US$}}700 and {{US$}}789 respectively.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |publisher=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}} In 2016 it was the 293rd most prescribed medication in the United States with more than a million prescriptions.{{cite web |title=The Top 300 of 2019 |url=https://clincalc.com/DrugStats/Top300Drugs.aspx |publisher=clincalc.com |accessdate=22 December 2018}}
=[[Ezetimibe]]=
A month supply in the United Kingdom costs the NHS about £26.21 as of 2019.BNF76, page 196 In the United States the wholesale cost of this amount is about US$5.85.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=Cost=
In the United States as of 2019 it costs about 0.21 USD per dose. In 2015, it cost between US$4.84 and 7.88.{{cite news|last1=Langreth|first1=Robert|title=Decoding Big Pharma’s Secret Drug Pricing Practices|url=https://www.bloomberg.com/graphics/2016-drug-prices/|accessdate=15 July 2016|publisher=Bloomberg|date=June 29, 2016}}
=[[Factor VIII (medication)]]=
The wholesale cost in the developing world is about US$119–497 per 500 IU vial.{{cite web|title=Factor Viii|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=911&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Famotidine]]=
A month supply in the United Kingdom costs the NHS about 30 ₤ as of 2019.BNF76, pages 74–75 In the United States the wholesale cost of this amount is about 2 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 |language=en}}
=[[Febuxostat]]=
In the United Kingdom a month of treatment costs the NHS about 24 pounds.BNF76, page 1087 In the United States the wholesale cost of a month's worth of medication is about US$320.{{cite web |title=NADAC as of 2019-02-20 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-20/4nuv-8qfq |website=Centers for Medicare and Medicaid Services |accessdate=26 February 2019 |language=en}}
=[[Fenofibrate]]=
A month supply in the United Kingdom costs the NHS about 3.67 £ per month as of 2019.BNF76, page 198 In the United States the wholesale cost of this amount is about US$8.40.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Fentanyl]]=
For a 100 microgram vial, the average wholesale cost in the developing world was {{US$}}0.66 in 2015.{{cite web|title=Single Drug Information|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=343&searchYear=2015|website=International Medical Products Price Guide|access-date=14 December 2017|df=dmy-all}} In 2017, the price in the United States was {{US$}}0.49 for that same amount.{{cite web|title=NADAC as of 2017-12-13|url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2017-12-13/iqwu-vhmf|website=Centers for Medicare and Medicaid Services|access-date=14 December 2017|df=dmy-all}}
==Cost==
The wholesale cost in the developing world {{as of|2015|lc=y}} is between {{US$}}0.08 and {{US$}}0.81 per 100 microgram vial. In the United States this amount costs about {{US$}}0.40 {{as of|2017|lc=y}}. In the United States the patches cost {{US$}}11.22 for a 12 µg/hr version and {{US$}}8.74 for a 100 µg/hr version.
=[[Ferrous salt/folic acid]]=
The wholesale cost in the developing world is about 0.07 to 1.02 USD a month.{{cite web|title= Ferrous Salt + Folic Acid|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=348&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom, it costs the NHS about 2.64 to 4.25 pounds per month.BNF69, page 661
=[[Filgrastim]]=
The wholesale cost in the developing world is about {{US$}}3.95 to {{US$}}94.66 per dose.{{cite web |title=Filgrastim |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1646&searchYear=2014|website=International Drug Price Indicator Guide |access-date=8 December 2016 }}{{cite web|title=Filgrastim- ERC: International Drug Price Indicator Guide |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1046&searchYear=2014|website=erc.msh.org|access-date=19 December 2016 }} In the United Kingdom it cost the NHS about £50.15 per 300 μg dose.BNF69, page 678 In the United States treatment costs more than {{US$}}200.TarasconPP2015, page 292 Filgrastim biosimilar medications are also available.{{cite web|title=Filgrastim|url=https://www.drugs.com/monograph/filgrastim.html |publisher=The American Society of Health-System Pharmacists|access-date=8 December 2016}}
=[[Finasteride]]=
A month supply in the United Kingdom costs the NHS about £0.89 per month as of 2019.BNF76, page 769 In the United States the wholesale cost of this amount is about US$2.34.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Flecainide]]=
A month supply in the United Kingdom costs the NHS about £7.68 as of 2019.BNF76, page 103 In the United States the wholesale cost of this amount is about 18.60 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Fluconazole]]=
The wholesale cost in the developing world is about US$0.05–0.10 per day.{{cite web|title=Fluconazole|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=906&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States the wholesale price is about US$1.14–1.75 per day as of 2016.{{cite web|title=NADAC as of 2016-12-07 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services|accessdate=11 December 2016}}
=[[Fludarabine]]=
The wholesale cost in the developing world is about US$54.00 per 50 mg vial.{{cite web|title=Fludarabine Phosphate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=351&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom it costs about 155.00 pounds per 50 mg vial.BNF69, page 590
=[[Fluorescein (medical use)]]=
The wholesale cost in the developing world is about US$12.25 per 5 ml bottle.{{cite web|title=Fluorescein|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1590&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom a single dose costs the NHS about 0.43 pounds.BNF69, pages 769, 772 It is also not very expensive in the United States.TarasconPP2015, page 416
=[[Fluorouracil]]=
The wholesale cost in the developing world is about US$1.18–3.40 per 500 mg vial.{{cite web|title=Fluorouracil|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=356&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom this amount costs the NHS about £6.40.BNF69, page 590 In the United States it costs about $18.71.{{cite web|title=Fluorouracil Prices, Coupons & Patient Assistance Programs - Drugs.com|url=https://www.drugs.com/price-guide/fluorouracil|website=Drugs.com|accessdate=27 June 2017}}
=[[Fluoxetine]]=
The wholesale cost in the developing world is between {{US$}}0.01 and {{US$}}0.04 per day as of 2014.{{cite book | veditors = Frye JE, Johnson K | publisher = Management Sciences for Health | location = Medford, Massachusetts | chapter = Fluoxetine | title = International Drug Price Indicator Guide | chapter-url = http://mshpriceguide.org/wp-content/uploads/2016/06/MSH-International-Drug-Price-Indicator-Guide-2014.pdf | date = 2014 }} In the United States, it costs about {{US$}}0.85 per day.{{cite web|title=Fluoxetine Hydrochloride|url=https://www.drugs.com/monograph/fluoxetine-hydrochloride.html|publisher=The American Society of Health-System Pharmacists|access-date=2 December 2015|df=dmy-all}} In 2016 it was the 29th most prescribed medication in the United States with more than 23 million prescriptions.{{cite web |title=The Top 300 of 2019 |url=https://clincalc.com/DrugStats/Top300Drugs.aspx |website=clincalc.com |accessdate=22 December 2018}}
=[[Fluphenazine]]=
In the United States the tablets costs between $0.22 and $0.42 per day for a typical dose.{{cite web|title=fluphenazine decanoate|url=https://www.drugs.com/monograph/fluphenazine-decanoate.html|publisher=The American Society of Health-System Pharmacists|access-date=Dec 1, 2015} The wholesale cost in the developing world of the long acting form is between US$0.20 and US$6.20 per injection as of 2014.{{cite web |title=Fluphenazine Decanoate |url= http://mshpriceguide.org/en/single-drug-information/?DMFId=358&searchYear=2014 |website=International Drug Price Indicator Guide|access-date=2 December 2015 }}
==Availability==
In the United States the tablets costs between 0.22 and 0.42 USD per day for a typical dose. The wholesale cost in the developing world of the long acting form is between 0.20 and 6.20 USD per injection as of 2014.
=[[Fluticasone propionate]]=
In the United States the wholesale cost per spray is about 0.33 USD as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}} In the United Kingdom, it costs the NHS about 0.13 GBP per spray as of 2019.BNF76, pages 262, 1172
=[[Fluticasone/salmeterol]]=
A two month supply in the United Kingdom costs the National Health Service about £35 per month as of 2019.BNF76, pages 263–264 In the United States the wholesale cost of this amount is about 89 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Folate]]=
The wholesale cost of supplements in the developing world is between US$0.001 and 0.005 per dose as of 2014.{{cite web|title=Folic Acid|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=361&searchYear=2014|website=International Drug Price Indicator Guide|access-date=1 September 2016}}
=[[Fremanezumab]]=
The wholesale cost in the United States as of 2019 is $US 369.90 per month.{{cite web |title=NADAC as of 2019-07-10 {{!}} Data.Medicaid.gov |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-07-10/8ghf-3bkk |website=Centers for Medicare and Medicaid Services |accessdate=15 July 2019 |language=en}}
=[[Furosemide]]=
In the United States, it is available as a generic medication and costs about US$0.15 per day.{{cite web|title=Furosemide|url=https://www.drugs.com/monograph/furosemide.html|publisher=The American Society of Health-System Pharmacists|accessdate=October 23, 2015|url-status=live|archiveurl=https://web.archive.org/web/20151119161939/http://www.drugs.com/monograph/furosemide.html|archivedate=2015-11-19}}
=[[Gabapentin]]=
The wholesale price in the developing world {{as of|2015|lc=y}} was about {{USD|10.80|link=yes}} per month;{{cite web |title = Gabapentin |url = http://mshpriceguide.org/en/single-drug-information/?DMFId=1036&searchYear=2015 |website = International Drug Price Indicator Guide |access-date = 13 March 2016 }} in the United States, it was US$100 to US$200.TarasconPP2015, page 327
=[[Gemcitabine]]=
The wholesale cost in the developing world is about US$24.41 to $316.99 per gram vial.{{cite web|title=Gemcitabine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1536&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United Kingdom a 1 g vial costs the NHS approximately £155.BNF69, page 590
=[[Gemfibrozil]]=
A month supply in the United Kingdom costs the NHS about 30 £ as of 2019.BNF76, pages 198–199 In the United States the wholesale cost of this amount is about 6 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Gentamicin]]=
The injectable's wholesale cost in the developing world in 2014 was between US$0.05 and US$0.58 per mL.{{cite web|title=Gentamicin sulfate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=369&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=15 August 2015}}
=[[Glecaprevir/pibrentasvir]]=
In the United States, a course of treatment costs about $27,600 as of 2019.{{cite web |title=Mavyret Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/mavyret |website=Drugs.com |language=en}} This amount in the United Kingdom costs the NHS about £26,000 as of 2018.BNF76, page 620
=Cost=
In the United States, a course of treatment costs about $27,600 as of 2019.{{cite web |title=Mavyret Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/mavyret |website=Drugs.com |language=en}} This amount in the United Kingdom costs the NHS about £26,000 as of 2018 while in Canada it is CA$40,000.{{cite journal |title=Pharmacoeconomic Review Report: Glecaprevir / Pibrentasvir (Maviret): (AbbVie Corporation): Indication: Hepatitis C genotype 1 to 6 [Internet]. |date=February 2018 |pmid=30462452}}
=[[Glibenclamide]]=
A month supply in the United Kingdom costs the NHS about £3.20 as of 2019.BNF76, page 692 In the United States the wholesale cost of this amount is about $2.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Gliclazide]]=
The wholesale cost in the developing world is about US$2.46–3.92 per month.{{cite web|title=Gliclazide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1079&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom a month of medication costs the NHS about 2.12 pounds.BNF69, page 474
=[[Glimepiride]]=
A month supply in the United Kingdom costs the NHS about 7.00 £ per month as of 2019.BNF76, page 693 In the United States, the wholesale cost of this amount is about 2.15 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Glipizide]]=
In the United States the wholesale cost per dose is less than 0.05 USD as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}} In the United Kingdom it costs the NHS less than 0.05 pounds per dose as of 2018.BNF76, page 693
=[[Glucagon (medication)]]=
The wholesale cost in the developing world is about {{US$}}25.75 a dose.{{cite web|title=Glucagon|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=374&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom that dose costs the NHS about £11.52.BNF69, page 487 In the United States the wholesale cost of a dose is {{US$}}247.32.{{cite web|title=NADAC as of 2016-12-21 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-21/6ebu-k7ew|website=Centers for Medicare and Medicaid Services|accessdate=27 December 2016}}
=[[Glutaraldehyde]]=
The wholesale cost in the developing world is about US$1.50–7.40 per liter of 2% solution.{{cite web|title=Glutaraldehyde|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=375&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
==History and culture==
The wholesale cost in the developing world is about US$1.50–7.40 per liter of 2% solution.{{cite web|title=Glutaraldehyde|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=375&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Griseofulvin]]=
The wholesale cost in the developing world is about US$0.05–0.18 per day.{{cite web|title=Griseofulvin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=381&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a course of treatment costs $100–200.TarasconPP2015, page 44
=[[Guaifenesin]]=
In the United States the wholesale cost is less than 0.10 USD per dose.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Guanfacine]]=
A month supply in the United Kingdom costs the NHS about £60 as of 2019.BNF76, pages 349–350 In the United States the wholesale cost of this amount is about 7.11 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[HPV vaccine]]=
The wholesale cost in the developing world is about {{US$|47}} a dose as of 2014.{{cite web|title=Vaccine, Hpv|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1472&searchYear=2014|website=International Drug Price Indicator Guide|access-date=6 December 2015|}} In the United States, it costs more than US$200.TarasconPP2015, page 314
<
=[[Halothane]]=
As of 2014, the wholesale cost in the developing world is about 22 to 52 USD for a 250 mL bottle.{{cite web|title=Halothane|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=389&searchYear=2014|website=International Drug Price Indicator Guide|access-date=13 August 2015}}
==Society and culture==
As of 2014, the wholesale cost in the developing world was 22 to 52 USD for a 250 mL bottle.{{cite web|title=Halothane|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=389&searchYear=2014|website=International Drug Price Indicator Guide|access-date=13 August 2015}}
=[[Hand sanitizer]]=
The wholesale cost in the developing world is about US$1.40–3.70 per liter bottle.{{cite web|title=Alcohol, isopropyl|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=15&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}{{cite book|title=The selection and use of essential medicines: Twentieth report of the WHO Expert Committee 2015 (including 19th WHO Model List of Essential Medicines and 5th WHO Model List of Essential Medicines for Children).|date=2015|publisher=WHO|isbn=9789240694941|pages=323|url=http://apps.who.int/iris/bitstream/10665/189763/1/9789241209946_eng.pdf?ua=1|accessdate=8 December 2016|url-status=live|archiveurl=https://web.archive.org/web/20161220085929/http://apps.who.int/iris/bitstream/10665/189763/1/9789241209946_eng.pdf?ua=1|archivedate=20 December 2016}}
=[[Heparin]]=
The wholesale cost in the developing world, when used for prevention, is about US$9.63–37.95 per month.{{cite web|title=Heparin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=391&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States it costs about $25–50 per month.TarasconPP2015
=[[Hepatitis B vaccine]]=
{{As of|2014}}, the wholesale cost in the developing world is {{US$|0.58–13.20}} per dose.{{cite web|title=Vaccine, Hepatitis B|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=791&searchYear=2014|website=International Drug Price Indicator Guide|access-date=6 December 2015}} In the United States it costs {{US$|50–100}}.TarasconPP2015, page 314
|Costa Rica ||97
=[[Hib vaccine]]=
The wholesale cost of a pentavalent vaccine which includes Hib in the developing world was US$15.40 per dose as of 2014.{{cite web|title=Vaccine, Pentavalent|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1556&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=7 December 2015}} In the United States it costs about $25–50 per dose.TarasconPP2015, page 313
=[[Hormonal IUDs]]=
The wholesale cost in the developing world is about US$122.46 each.{{cite web|title=IUD (Levonorgestrel)|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1599&searchYear=2014 |publisher=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom they cost the NHS about £88.BNF69, page 556 In the United States they cost around US$844.00,{{cite book|last1=Zieman|first1=Mimi|title=Managing Contraception 2012–2014|publisher=Managing Contraception|isbn=9781467536400|chapter=Chapter 27|chapter-url=https://books.google.com/books?id=SdUDdQtGMGoC&pg=PT378|df=dmy-all|year=2012}}
=[[Hydralazine]]=
The wholesale cost in the developing world is about US$2.78–9.11 per month.{{cite web|title=Hydralazine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=395&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States treatment costs about $50–100 per month.TarasconPP2015, page 145
=[[Hydrochlorothiazide/triamterene]]=
A month supply in the United Kingdom costs the NHS about 0.95 £ per month as of 2019.BNF76, page 76 In the United States the wholesale cost of this amount is about 3.90 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Hydrocodone]]=
In the United States the wholesale cost of the long-acting formulation is about 10 to 30 USD per dose as of 2019.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 }}
=[[Hydrocortisone]]=
The wholesale cost in the developing world is about {{US$}}0.27 per day as of 2014 for the form taken by mouth.{{cite web|title=Hydrocortisone|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1422&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=1 September 2016}} In the United States, it costs less than {{US$}}25 for a typical month of treatment.TarasconPP2015, page 202
=[[Hydromorphone]]=
In the United Kingdom it costs the NHS about £0.32 per 2 mg tablet as of 2019.BNF76, pages 24, 456 In the United States the wholesale cost of this amount is about {{US$}}0.07.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Hydroxocobalamin]]=
The wholesale cost in the developing world is about {{US$}}0.12 to {{US$}}0.84 per dose (1 ml with 1 mg/ml concentration).{{cite web|title=Vitamin B12|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=823&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United States the same amount costs about {{US$}}0.84 wholesale.{{cite web|title=NADAC as of 2016-12-07 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services|access-date=30 December 2016|}}
=[[Hydroxycarbamide]]=
The wholesale cost in the developing world is about US$0.35–0.47 per day.{{cite web|title=Hydroxycarbamide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=408&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States it costs less than $25 a month.TarasconPP2015, page 295
=[[Hydroxychloroquine]]=
The wholesale cost in the developing world is about $5.40 to 7.44 per month.{{cite web|title=Hydroxychloroquine Sulfate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=909&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom this dose costs the NHS about £5.15.BNF69, page 730 In the United States the wholesale cost of a month of treatment is about US$25 as of 2019.{{cite web |title=NADAC as of 2019-08-07 {{!}} Data.Medicaid.gov |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-08-07/m7ng-9e3x |website=Centers for Medicare and Medicaid Services |accessdate=9 August 2019 }}
=[[Hydroxyzine]]=
In the United Kingdom 28 doses cost less than a pound.BNF74 In the United States the wholesale cost in 2018 was about 0.05 USD per dose.{{cite web|url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-11-21/j5j5-fxwa|title=NADAC as of 2018-11-21|website=Centers for Medicare and Medicaid Services|accessdate=21 Nov 2018}}
=[[Hyoscine butylbromide]]=
The wholesale cost in the developing world is US$0.004–0.11 per pill as of 2014.{{cite web|title=Hyoscine Butylbromide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=412&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=4 December 2015}}
=[[Ibuprofen]]=
The wholesale cost in the developing world is between {{US$}}0.01 and {{US$}}0.04 per dose.{{cite web|title=Ibuprofen|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=416&searchYear=2014|accessdate=12 January 2016}} In the United States, it costs about {{US$}}0.05 per dose.{{cite web|url=https://www.drugs.com/monograph/ibuprofen.html|title=Ibuprofen|last=|first=|date=|website=|publisher=The American Society of Health-System Pharmacists|access-date=2016-10-12|df=dmy-all}}
=[[Ifosfamide]]=
The wholesale cost in the developing world is about US$7.35–70.70 per 2 gm vial.{{cite web|title=Ifosfamide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1542&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the UK this dose costs the NHS about 130.04 pounds.BNF69, page 580
=[[Imipenem/cilastatin]]=
The wholesale cost in the developing world is about US$12.68 to $60 per day.{{cite web|title=Imipenem + Cilastatin |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=422&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States it costs more than $200 for a course of treatment.TarasconPP2015
=[[Influenza vaccine]]=
The wholesale price in the developing world is about US$5.25 per dose {{as of|2014|lc=yes}}.{{cite web|title=Vaccine, influenza|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=792&searchYear=2014|publisher=International Drug Price Indicator Guide|access-date=December 6, 2015}} In the United States, the vaccine costs less than US$25 per dose, {{as of| 2015|lc=yes}}.TarasconPP2015, page 314
<
=[[Insulin (medication)]]=
The wholesale cost in the developing world is about US$2.39 to $10.61 per 1,000 iu (34.7 mg) of regular insulin and $2.23 to $10.35 per 1,000 iu of NPH insulin.{{cite web|title=Insulin, Neutral Soluble|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=431&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}}{{cite web|title=Insulin, isophane|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=430&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United Kingdom 1,000 iu of regular or NPH insulin costs the NHS £7.48, while this amount of insulin glargine costs £30.68.BNF69, pages 464–472
<
=[[Insulin aspart]]=
In the United Kingdom it costs the NHS about £1.89 per 100 units as of 2019.BNF76, page 697 In the United States the wholesale cost of this amount is about US$30.00.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Insulin detemir]]=
In the United Kingdom it costs the NHS about £2.80 per 100 units as of 2019.BNF76, page 701 In the United States the wholesale cost of this amount is about US$29.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Insulin glargine]]=
In the United States the wholesale cost per 100 units is about {{US$}}26 USD as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}} In the United Kingdom this amount costs the NHS about £2.35.BNF76, page 701
=[[Insulin lispro]]=
In the United Kingdom it costs the NHS about £1.89 per 100 units as of 2019.BNF76, page 698 In the United States the wholesale cost of this amount is about US$30.00.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=Cost=
In the United States, in 2015, the cost was between $10.06 and $29.36 per 100 units.{{cite news|last1=Langreth|first1=Robert|title=Decoding Big Pharma's Secret Drug Pricing Practices|url=https://www.bloomberg.com/graphics/2016-drug-prices/|accessdate=15 July 2016|publisher=Bloomberg|date=June 29, 2016}} In April of 2019, Eli Lilly and Company announced they would produce a version selling for $137.35 per vial, about half the current cost. The chief executive said that this was a contribution "to fix the problem of high out-of-pocket costs for Americans living with chronic conditions", but Patients for Affordable Drugs Now said this was just a public relations move, as "other countries pay $20 for a vial of insulin.”{{cite news |title=Drug company announces new version of insulin at half the price |url=https://thehill.com/policy/healthcare/432439-drug-company-announces-new-version-of-insulin-at-half-the-price |accessdate=15 April 2019 |publisher=The Hill |date=3 April 2019}}
The cost in the UK was between £1.66 (about $2.50) and £1.96 (about $3.00) per 100 units, in 2017.{{Cite web|url=http://www.mims.co.uk/drugs/diabetes/insulins/humalog|title=Humalog {{!}} MIMS online|website=www.mims.co.uk|access-date=2017-01-12}}
=[[Intravenous sodium bicarbonate]]=
The wholesale cost in the developing world is about US$0.09–2.58 per 10 ml of 8.4% solution.{{cite web|title=Sodium Bicarbonate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=723&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom this amount costs the NHS about 11.10 pounds.BNF69, page 684
=[[Intravenous sugar solution]]=
The wholesale cost in the developing world is about US$1.00–1.80 per liter of 10% dextrose in water, and it is about US$0.60–2.40 per liter of 5% dextrose in normal saline.{{cite web|title=Dextrose 10% in Water|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=248&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}{{cite web|title=Dextrose 5% in Sodium Chloride 0.9%|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=241&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom a 50 ml vial of 50% solution costs the NHS 2.01 pounds.BNF69, pages 683–684
=[[Iohexol]]=
The wholesale cost in the developing world is about US$10.99 per 50 ml vial.{{cite web|title=Iohexol|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=438&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a dose costs US$50–100.TarasconPP2015, page 171
=[[Ipratropium bromide]]=
The wholesale price in the developing world is about 6.60 USD for a 200 dose inhaler.{{cite web|title=Ipratropium Bromide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1228&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=5 December 2015}}{{dead link|date=November 2017 |bot=InternetArchiveBot |fix-attempted=yes }} In the United States, a month worth of medication costs 100 to 200 USD.TarasconPP2015, page 455
=[[Ipratropium bromide/salbutamol]]=
Sixty doses in the United Kingdom costs the NHS about 18 £ as of 2019.BNF76, page 247 In the United States the wholesale cost of this amount is about US$9.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Irbesartan]]=
A month supply in the United Kingdom costs the NHS less than two pounds as of 2019.BNF76, page 175 In the United States the wholesale cost of this amount is about six dollars.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Iron supplement]]=
The wholesale cost in the developing world is about US$0.05–0.63 per month.{{cite web|title=Ferrous Salt|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=344&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a typical month of treatment costs less than $25.TarasconPP2015, page 217
=[[Isoflurane]]=
The wholesale cost in the developing world is about US$17.24–170.40 per 250 ml bottle.{{cite web|title=Isoflurane|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=918&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}}
=[[Isoniazid]]=
The wholesale cost in the developing world is about US$0.60–4.75 per month.{{cite web|title=Isoniazid|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=445&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a month of treatment costs less than $25.TarasconPP2015, page 49
=[[Isoniazid/rifampicin]]=
The wholesale cost in the developing world is about {{US$|5.10}} a month.{{cite web|title=Rifampicin + Isoniazid|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=946&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom a month of medication costs the NHS about 28.11 pounds.BNF69, page 403
=[[Isosorbide dinitrate]]=
The wholesale cost in the developing world is about US$6.36 a month.{{cite web|title=Isosorbide Dinitrate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1501&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States it costs less than US$25 per month.TarasconPP2015, page 160
=[[Isosorbide mononitrate]]=
A month supply in the United Kingdom costs the NHS about one £ per month as of 2019.BNF76, pages 219–220 In the United States the wholesale cost of this amount is about US$4.30.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Itraconazole]]=
The wholesale cost in the developing world is about 0.29 USD per day of treatment {{as of|2015|lc=y}}.{{cite web|title=Single Drug Information|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=920&searchYear=2015|website=International Medical Products Price Guide|accessdate=9 December 2017}} In the United States, {{as of|2017|lc=y}}, the wholesale cost of this dose is 6.36 USD.{{cite web|title=NADAC as of 2017-12-06|url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2017-12-06/8h2n-xgjm|website=Centers for Medicare and Medicaid Services|accessdate=10 December 2017|language=en}}
=[[Ivermectin]]=
The wholesale cost in the developing world for the tablets is about US$0.12 for a course of treatment.{{cite web|title=Ivermectin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1376&searchYear=2014|website=International Drug Price Indicator Guide|access-date=January 16, 2016}} In the United States, the costs is less than US$50.TarasconPP2014, page 40{{cite web |title=NADAC as of 2019-09-25 {{!}} Data.Medicaid.gov |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-09-25/s3gx-n3zd |website=Centers for Medicare and Medicaid Services |accessdate=26 September 2019 |language=en}}
Ivermectin is more effective than albendazole and equally as effective as thiabendazole for treatment of threadworm (strongyloidiasis). Ivermectin has fewer adverse effects than does thiabendazole and is at least as well tolerated as albendazole.{{cite journal | vauthors = Henriquez-Camacho C, Gotuzzo E, Echevarria J, White AC, Terashima A, Samalvides F, Pérez-Molina JA, Plana MN | title = Ivermectin versus albendazole or thiabendazole for Strongyloides stercoralis infection | journal = The Cochrane Database of Systematic Reviews | volume = | issue = 1 | pages = CD007745 | date = January 2016 | pmid = 26778150 | pmc = 4916931 | doi = 10.1002/14651858.CD007745.pub3 }} An analysis based on an economic model suggests that it is cost effective for people moving to Europe from areas where threadworm is common to be given a single-dose of ivermectin on arrival so as to cure presumptive infection with threadworm.{{cite journal |vauthors=Agbata EN, Morton RL, Bisoffi Z, Bottieau E, Greenaway C, Biggs BA, Montero N, Tran A, Rowbotham N, Arevalo-Rodriguez I, Myran DT, Noori T, Alonso-Coello P, Pottie K, Requena-Méndez A |title=Effectiveness of Screening and Treatment Approaches for Schistosomiasis and Strongyloidiasis in Newly-Arrived Migrants from Endemic Countries in the EU/EEA: A Systematic Review |journal=Int J Environ Res Public Health |volume=16 |issue=1 |pages= 11|date=December 2018 |pmid=30577567 |doi=10.3390/ijerph16010011 |url=|pmc=6339107 }} Persons who are immunocompromised or who will receive immunosuppressive treatment and who have confirmed or presumptive threadworm infestation are likely to benefit from treatment with ivermectin.{{cite book | last1=Kotton | first1=Camille | last2=Mileno | first2=Maria | first3 = J. |last3 = Keystone | title = Travel medicine | chapter = The Immunocompromised Traveler| pages = 269–277 | publisher = Elsevier | location = Edinburgh | year = 2019 | isbn = 978-0-323-54696-6 }}
==Cost==
The wholesale cost in the developing world is about US$0.12 for a course of treatment as of 2014. This is down from an initial cost of US$6 proposed by Merck in 1987.{{cite journal |last1=Crump |first1=A |last2=Ōmura |first2=S |title=Ivermectin, 'wonder drug' from Japan: the human use perspective. |journal=Proceedings of the Japan Academy. Series B, Physical and Biological Sciences |date=2011 |volume=87 |issue=2 |pages=13–28 |doi=10.2183/pjab.87.13 |pmid=21321478|bibcode=2011PJAB...87...13C }}
In the United States a course of treatment with pills costs about US$25–50 for a typical adult. As of 2019 ivermectin tablets were the least expensive treatment option for lice in children at about US$10.{{cite book |last1=Kliegman |first1=Robert M. |last2=Geme |first2=Joseph St |title=Nelson Textbook of Pediatrics E-Book |date=2019 |publisher=Elsevier Health Sciences |isbn=9780323568883 |page=3575 |url=https://books.google.ca/books?id=LJuRDwAAQBAJ&pg=PA3867 |language=en}} The hair lotion, however, is about US$300 for a course of treatment.
=[[Kanamycin A]]=
The wholesale cost in the developing world is US$0.85–1.52 per dose as of 2014.{{cite web|title=Kanamycin Sulfate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=452&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=7 December 2016}}
=[[Ketamine]]=
The wholesale price in the developing world is between US$0.84 and US$3.22 per vial.{{cite web |title=Ketamine |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=454&searchYear=2014 |accessdate=12 January 2016 |df=dmy-all}}
=[[Ketoconazole]]=
A 30-gram tube in the United Kingdom costs the NHS less than £5 as of 2019.BNF76, page 1198 In the United States, where the topical cream is available only by prescription, the wholesale cost of this amount is about {{US$|6.30}}.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Ketorolac]]=
In the United Kingdom it costs the NHS less than £1 per injectable dose as of 2019.BNF76, pages 1144, 1302–1303 In the United States the wholesale cost of this amount is about US$1.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 |language=en}}
=[[Labetalol]]=
A month supply in the United Kingdom costs the NHS about 8 £ as of 2019.BNF76, pages 147–148 In the United States the wholesale cost of this amount is about US$12.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Lactulose]]=
In various countries it could be purchased for about {{USD}}0.16 per 15 ml of syrup (10 g of lactulose) in 2015.{{cite web|title=Lactulose|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=922&searchYear=2015|website=mshpriceguide.org|access-date=26 March 2017}}{{cite web|url=https://www.weldricks.co.uk/products/lactulose-solution-500ml|title=Lactulose Solution 500ml|website=Weldricks Pharmacy (UK)|access-date=31 March 2017}} A UK source of lactulose at £2.95 for 500 ml ($0.11/15 ml). In the United States, the cost of this amount is about US$0.63.{{cite web |url=https://www.drugs.com/price-guide/lactulose |title=Lactulose Prices, Coupons & Patient Assistance Programs |website=Drugs.com |access-date=25 March 2017 }} Source gives cost for 473 ml as about $20.
==Cost==
The wholesale price is about US$0.18 per 15-ml dose.{{cite web|title=Lactulose|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=922&searchYear=2014|website=International Drug Price Indicator Guide|access-date=11 August 2015}} In the United States, 30 doses of the liquid cost about $20.
=[[Lamivudine]]=
The wholesale cost in the developing world as of 2014 is about US$0.06 per day.{{cite web|title=Lamivudine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1231&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=23 July 2016}} As of 2015 the cost for a typical month of medication in the United States is more than $200.TarasconPP2015, page 65
==History==
As of 2015 the cost for a typical month of medication in the United States is more than $200.TarasconPP2015, page 65
=[[Lamivudine/nevirapine/stavudine]]=
=[[Lamivudine/nevirapine/zidovudine]]=
The wholesale cost in the developing world is about 8.54 to 18.94 USD a month as of 2014.{{cite web|title=Lamivudine + Zidovudine + Nevirapine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1087&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Lamivudine/zidovudine]]=
The wholesale cost in the developing world is about US$6.90 to $29.64 per month.{{cite web|title=Lamivudine + Zidovudine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=457&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} As of 2015 the cost for a typical month of medication in the United States more than $200.TarasconPP2015, page 59
==Society and culture==
- Combivir: lamivudine 150 mg and zidovudine 300 mg (scored). 60 tablets cost $994.{{Cite web|url=http://www.healthline.com/health/hiv-aids/cost-of-treatment#1|title=The Cost of HIV Treatment|date=2015-04-02|access-date=2016-11-16}}
=[[Lamotrigine]]=
The wholesale cost in the developing world is about US$3.50 to US$23 per month as of 2015.{{cite web|title=Single Drug Information|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1601&searchYear=2015|website=International Medical Products Price Guide|access-date=9 December 2017}} In the United States, this amount has a wholesale cost of about US$4.60 as of 2019.{{cite web |title=NADAC as of 2019-11-27 {{!}} Data.Medicaid.gov |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-11-27/qjsh-shte |website=Centers for Medicare and Medicaid Services |accessdate=26 November 2019 |language=en}}
=[[Lansoprazole]]=
A one month supply, in the United Kingdom, costs the NHS less than £5, {{as of|2019|lc=yes}}.BNF76, pages 79–80 In the United States, the wholesale cost of this amount is about $5.40, as of 2019.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Latanoprost]]=
The wholesale cost in the developing world is about US$0.69–3.79 per 2.5 ml bottle.{{cite web|title=Latanoprost|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1057&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}{{dead link|date=November 2017 |bot=Level C |fix-attempted=yes }} In the United States a month of treatment costs less than $25.TarasconPP2015, page 413
=[[Lenalidomide]]=
In the United States it costs about US$16,000 to US$21,000 per month as of 2019.{{cite web |title=Revlimid Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/revlimid |website=Drugs.com |accessdate=27 October 2019 |language=en}} In the United Kingdom this amount costs the NHS about £3,400 to 4,400.BNF76, page 935
=Price=
Lenalidomide costs $163,381 per year for the average person in the United States.{{cite journal| title = Lenalidomide in Myeloma — A High-Maintenance Friend| journal = N Engl J Med | date = 10 May 2012| vauthors = Badros AZ| volume = 366| issue = 19| pages = 1836–1838| doi =10.1056/NEJMe1202819| pmid =22571206}}
=[[Levamisole]]=
The wholesale cost in the developing world is about {{US$}}0.18 to {{US$}}0.33 for a course of treatment.{{cite web|title=Levamisole|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=459&searchYear=2014|website=International Drug Price Indicator Guide|access-date=1 December 2016}}
=[[Levetiracetam]]=
A month supply in the United Kingdom costs the NHS about £19.31 per month as of 2019.BNF76, page 319 In the United States the wholesale cost of this amount is about {{USD}}4.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Levocetirizine]]=
A month supply in the United Kingdom costs the NHS about 4.50 £ as of 2019.BNF76, pages 280–281 In the United States the wholesale cost of this amount is about US$3.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Levofloxacin]]=
The wholesale cost in the developing world is about US$0.44–0.95 per week of treatment.{{cite web|title=Levofloxacin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1088&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=August 25, 2016}} In the United States a week of treatment costs about $50–100.TarasconPP2015, page 102
=[[Levonorgestrel]]=
The wholesale cost in the developing world is between $0.23 and $1.65 US for the dose required for emergency birth control.{{cite web|title=Levonorgestrel|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1603&searchYear=2014|website=International Drug Price Indicator Guide|access-date=21 August 2015}}
=[[Levonorgestrel-releasing implant]]=
The wholesale cost in the developing world is about US$8.93–13.29 per set.{{cite web|title=Levonorgestrel|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1234&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Levothyroxine]]=
The wholesale cost in the developing world is about {{US$}}0.58 to {{US$}}12.28 per month.{{cite web|title=Levothyroxine |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=466&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United States, a typical month of treatment costs less than {{US$}}25.TarasconPP2015, page 223
=[[Lidocaine]]=
It is available as a generic medication and is not very expensive.{{cite web|title=Lidocaine Hydrochloride (Local)|url=https://www.drugs.com/monograph/lidocaine-hydrochloride-local.html|publisher=The American Society of Health-System Pharmacists|accessdate=Aug 26, 2015}}TarasconPP2015, page 22 The wholesale cost in the developing world in 2014 was {{US$|0.45}} to $1.05 wholesale per 20 ml vial of medication.{{cite web|title=Lidocaine HCL|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=473&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=27 August 2015}}
=[[Linagliptin]]=
A month supply in the United Kingdom costs the NHS about £33.26 as of 2019.BNF76, page 680 In the United States the wholesale cost of this amount is about 391 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Liothyronine]]=
A month's supply in the United Kingdom costs the NHS about {{GBP}}247 as of 2019.BNF76, page 757 In the United States the wholesale cost of this amount is about {{USD}}22.40.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
==Pricing==
The British Competition and Markets Authority launched an investigation into the alleged "excessive and unfair pricing" of liothyronine tablets in 2017. It alleged that Advanz Pharma overcharged the NHS from before 2007 to July 2017. The price of a pack increased by almost 1,600% from £4.46 before it was debranded in 2007 to £258.19 by July 2017.{{cite news |title=CMA investigates 1,600% price increase of liothyronine over eight-year period |url=https://www.pharmaceutical-journal.com/20206079.article |accessdate=17 March 2019 |publisher=Pharmaceutical Journal |date=31 January 2019}}
=[[Liraglutide]]=
A month supply in the United Kingdom costs the NHS about £78.50 as of 2019.BNF76, page 685 In the United States the wholesale cost of this amount is about US$98.30.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Lisdexamfetamine]]=
A month supply in the United Kingdom costs the British National Health Service about {{currency|amount=58.00|code=POUND}} {{as of|2019|lc=y|post=.}}BNF76, pages 348–349 In the United States, the wholesale cost of this amount is about {{Currency|amount=264|code=US}}.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Lisinopril]]=
In the United States the wholesale cost per month was less than 0.70 USD as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}} In the United Kingdom it cost the NHS about 10 pounds per month as of 2018.BNF76, page 170
=[[Lisinopril/hydrochlorothiazide]]=
In the United States the wholesale cost per dose is less than US$0.05 {{as of|2018|lc=yes}}.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 }} In the United Kingdom it costs the NHS about 0.40 pounds per dose {{as of|2017|lc=yes}}.BNF74, page 166
=[[Lithium (medication)]]=
The wholesale cost in the developing world in 2014 was between 0.12 and 0.20 USD per day.{{cite web|title=Lithium Carbonate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=481&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=1 December 2015}} In the United States at usual doses it costs about 0.90 to 1.20 USD per day.{{cite web|title=Lithium Salts|url=https://www.drugs.com/monograph/lithium-salts.html|publisher=The American Society of Health-System Pharmacists|accessdate=Dec 1, 2015}}
=[[Loperamide]]=
Loperamide is available as an inexpensive generic medication.{{cite web|title=Loperamide Hydrochloride|url=https://www.drugs.com/monograph/loperamide-hydrochloride.html|publisher=The American Society of Health-System Pharmacists|accessdate=25 August 2015|df=dmy-all}}TarasonPP2013, page 217 The wholesale cost in the developing world is about {{US$|0.004}} to 0.040 per dose.{{cite web|title=Loperamide HCL|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=482&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=26 August 2015|df=dmy-all}} In August 2016, the US retail cost is about US$0.31 per dose.{{Cite web|url=https://data.medicaid.gov/Drug-Prices/NADAC-National-Average-Drug-Acquisition-Cost-/a4y5-998d|title=NADAC (National Average Drug Acquisition Cost) Loperamide|website=Centers for Medicare and Medicaid Services|access-date=16 April 2016|quote=Loperamide 2mg Capsule ... 0.33803 [USD] ... 03/23/2016|df=dmy-all}}
==Cost==
=[[Loratadine]]=
The wholesale cost in the developing world is about US$0.01 to 0.06 per dose as of 2015.{{cite web|title=Loratadine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=925&searchYear=2015|website=International Drug Price Indicator Guide|access-date=1 June 2018}}
=[[Lorazepam]]=
The wholesale cost in the developing world of 1 mg dose by mouth is about US$0.02 to US$0.21 as of 2015.{{cite web |title=Lorazepam |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=483&searchYear=2015 |website=International Medical Products Price Guide |accessdate=29 November 2019}} This amount in the United Kingdom costs the NHS about £0.14.BNF76, page 336 In the United States as of 2015 a typical month's supply is less than US$25.TarasconPP2015, page 437
=[[Losartan]]=
The wholesale cost in the developing world is about US$0.28–3.45 per month as of 2015.{{cite web|title=Single Drug Information|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=484&searchYear=2015|website=International Medical Products Price Guide|accessdate=9 December 2017}} In the United States, as of 2017, the wholesale cost of a typical dose is $1.13 per month.{{cite web|title=NADAC as of 2017-12-06|url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2017-12-06/8h2n-xgjm|website=Centers for Medicare and Medicaid Services|accessdate=10 December 2017}}
=[[Losartan/hydrochlorothiazide]]=
A month supply in the United Kingdom costs the NHS about 1.50 £ per month as of 2019.BNF76, page 176 In the United States the wholesale cost of this amount is about US$2.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Lovastatin]]=
In the United States the wholesale cost is about 0.05 USD per dose.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Lurasidone]]=
A month supply in the United Kingdom costs the NHS about £90.72 as of 2019.BNF76, pages 393–394 In the United States the wholesale cost of this amount is about {{US$}}190.20.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Macrogol]]=
In the United Kingdom it costs the NHS about £0.14 per dose as of 2019.BNF76, pages 57–58 In the United States the wholesale cost of this amount is about US$1.40.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Magnesium sulfate (medical use)]]=
The wholesale cost in the developing world is about US$0.35–8.73 per 10 ml of 50% solution.{{cite web|title=Magnesium Sulfate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=489&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom 4 ml of 20% solution costs the NHS about 10.23 pounds.BNF69, page 696 In the United States a course of medication typically costs less than $25.TarasconPP2015, page 220
=[[Mannitol]]=
The wholesale cost in the developing world is about 1.12 to US$5.80 per dose.{{cite web|title=Mannitol|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=491&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United States, a course of treatment costs $25 to $50.TarasconPP2015, page 344
=[[Measles vaccine]]=
The wholesale cost in the developing world is about 0.70 USD per dose as of 2014.{{cite web|title=Vaccine, Measles|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=793&searchYear=2014|website=International Drug Price Indicator Guide|access-date=6 December 2015}}
=[[Mebendazole]]=
The wholesale cost in the developing world is between USD 0.004 and 0.04 per dose.{{cite web|title=Mebendazole|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=493&searchYear=2014|website=International Drug Price Indicator Guide|access-date=18 August 2015}} In the United States a single dose is about USD 440.00 as of 2016, while in Australia and the UK it costs about USD 5.00.{{cite news|last1=Crow|first1=David|title=US drugmaker charges 200 times UK price for common worm pill|url=https://www.ft.com/content/f0080fe4-c3ad-11e6-9bca-2b93a6856354|access-date=8 January 2017|work=www.ft.com|date=18 December 2016|url-access=subscription }}
==Cost==
In the developing world the wholesale cost is between USD 0.004 and 0.04 per dose as of 2014. In the United States a single dose was about USD 18.00 in 2015.{{cite web|title=Mebendazole|url=https://www.drugs.com/monograph/mebendazole.html|publisher=The American Society of Health-System Pharmacists|access-date=Aug 18, 2015}} In 2016 the price increased to USD 440.00 per dose in the U.S. as Amedra Pharmaceuticals acquired the rights from Teva in 2013.
=[[Meclizine]]=
In the United States the wholesale cost per dose is about US$0.03.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 |language=en}}
=[[Medroxyprogesterone acetate]]=
The wholesale cost in the developing world is about US$0.59–1.57 per vial.{{cite web|title=Medroxyprogesterone Acetate | url = http://mshpriceguide.org/en/single-drug-information/?DMFId=497&searchYear=2014 | website = International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom this dose costs the NHS about 6.01 pounds.BNF69, page 555 In the United States it costs less than $25 a dose as of 2015.TarasconPP2015, page 363
=[[Mefloquine]]=
The wholesale price in the developing world is about US$0.6–1.3 per dose.{{cite web|title=Mefloquine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=499&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=27 November 2015}} In the United Kingdom it costs the NHS £1.82 per dose.BNF76, page 607 In the United States it costs about $10 a dose.{{cite web|title=Mefloquine Hydrochloride|url=https://www.drugs.com/monograph/mefloquine-hydrochloride.html|work=The American Society of Health-System Pharmacists|accessdate=27 Nov 2015}}
=[[Meglumine antimoniate]]=
The wholesale cost in the developing world is about 4.32 USD per vial as of 2014.{{cite web|title=Meglumine Antimonate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=502&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Meloxicam]]=
In the United States the wholesale cost per dose is less than US$0.02 {{as of|2018|lc=yes}}.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare & Medicaid Services (CMS) |access-date=22 December 2018 }} In the United Kingdom it costs about 0.13 pounds {{as of|2018|lc=yes}}.BNF76, pages 1112–1113
=[[Melphalan]]=
In the United Kingdom it costs the NHS £137 per 50 mg vial.BNF76, pages 873–874 In the United States the cost of this amount is US$257.{{cite web |title=Melphalan Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/melphalan |website=Drugs.com |accessdate=27 October 2019 |language=en}}
=[[Memantine]]=
A month supply in the United Kingdom costs the NHS about 1.60 GBP as of 2019.BNF76, pages 303–304 In the United States the wholesale cost of this amount is about US$5.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 |language=en}}
==History==
The cost of Namenda was $269 to $489 a month in 2012.{{cite web | url = http://www.consumerreports.org/health/resources/pdf/best-buy-drugs/AlzheimersFINAL.pdf | work = Consumer Reports Health | title = Evaluating Prescription Drugs Used to Treat: Alzheimer's Disease. Comparing Effectiveness, Safety, and Price. | date = May 2012 }}
=[[Meningococcal vaccine]]=
The wholesale cost in the developing world is between US $3.23 and $10.77 per dose as of 2014.{{cite web|title=Vaccine, Meningococcal|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=796&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=6 December 2015}} In the United States it costs $100–200 for a course.TarasconPP2015, page 315
=[[Mercaptopurine]]=
The wholesale cost in the developing world is about US$18.42–200.16 a month.{{cite web|title=Mercaptopurine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=505&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom this costs the NHS about 121.13 pounds per month.BNF69, page 590 In the United States the wholesale cost is about $99.16 per month as of 2016.{{cite web|title=NADAC as of 2016-12-07 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services|accessdate=21 December 2016}}
=[[Meropenem]]=
The wholesale cost in the developing world is between 3.44 and 20.58 USD per one gram vial as of 2015.{{cite web|title=Single Drug Information|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1313&searchYear=2015|website=International Medical Products Price Guide|accessdate=9 December 2017}} In the United Kingdom this amount costs the NHS about £16 in 2015.BNF69, page 379
=[[Meropenem/vaborbactam]]=
In the United States it costs about US$1,126 per day as of 2019.{{cite web |title=Vabomere Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/vabomere |website=Drugs.com |accessdate=6 November 2019 |language=en}}
=[[Mesalazine]]=
A month supply in the United Kingdom costs the NHS about £43 as of 2019.BNF76, pages 39-41 In the United States the wholesale cost of this amount is about 288 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Mesna]]=
The wholesale cost in the developing world is about US$3.50 per 400 mg vial.{{cite web|title=Mesna|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1550&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom this amount costs the NHS about £3.95.BNF69, page 578
=[[Metformin]]=
The wholesale price in the developed world was between {{US$}}0.21 and $5.55 per month as of 2014.{{cite web|title=Metformin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=508&searchYear=2014|access-date=11 January 2016|df=}} In the United States, it costs {{US$}}5 to {{US$}}25 per month.{{cite web|title=Metformin Hydrochloride|url=https://www.drugs.com/monograph/metformin-hydrochloride.html|publisher=The American Society of Health-System Pharmacists|access-date=2 January 2017}}
=[[Methocarbamol]]=
A month supply in the UK costs the NHS about £12.72 as of 2019.BNF76 In the US the wholesale cost of this quantity is about US$6.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Methotrexate]]=
The wholesale cost as of 2014 in the developing world is between US$0.06 and US$0.36 per day for the form taken by mouth.{{cite web |title=Methotrexate Sodium|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=510&searchYear=2014|website=International Drug Price Indicator Guide|access-date=23 August 2016}} In the United States, a typical month of treatment costs $25 to $50.TarasconPP2015, page 464
=[[Methyldopa]]=
The wholesale cost in the developing world is about US$4.31–9.48 per month.{{cite web|title=Methyldopa|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=514&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States it costs less than $25 per month.TarasconPP2015, page 140
=[[Methylene blue]]=
In the United States, a 50 mg vial costs about 191.40 USD.{{cite web|title=Provayblue Prices, Coupons & Patient Assistance Programs - Drugs.com|url=https://www.drugs.com/price-guide/provayblue|website=www.drugs.com|accessdate=12 January 2017}} In the United Kingdom, a 50 mg vial costs the NHS about £39.38.BNF69, page 34
=[[Methylphenidate]]=
In the United States, the wholesale cost of the immediate release formulation is less than US$0.30 per dose as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=19 December 2018 |language=en }}
== Cost ==
Generic immediate-release methylphenidate is relatively inexpensive. The average wholesale cost is about US$0.15 per defined daily dose (retail pharmacies normally charge more).Based on: {{cite web|title=Methylphenidate Hydrochloride|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=928&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=9 May 2016}} However, the most expensive brand-name extended-release tablets may retail for as much as $12.40 per defined daily dose.The [http://www.healthinfo.moh.gov.on.ca/formulary/ Ontario Drug Benefit online formulary] indicates that, in Ontario, Canada, the local most-expensive methylphenidate product is probably Concerta. Drug prices in the US are often higher than in Canada. The GoodRx website correctly points out that short-term refills (e.g. 30 tablets) often cost more per tablet than longer-term refills (e.g. 90 tablets). For 30 tablets of brand-name Concerta 27 mg, the relevant [http://www.goodrx.com/concerta?form=tablet&dosage=27mg&quantity=30&days_supply=&label_override=Concerta GoodRx webpage] {{Webarchive|url=https://web.archive.org/web/20160605082649/http://www.goodrx.com/concerta?form=tablet&dosage=27mg&quantity=30&days_supply=&label_override=Concerta |date=5 June 2016 }} offers coupons. However, if a patient ignores the coupons, and if the patient does not shop around, the website indicates that it is possible to pay more than twelve US dollars per defined daily dose. Data retrieved 17 May 2016.
=[[Methylprednisolone]]=
The wholesale cost in the developing world is about US$3.81–9.35 per 500 mg vial.{{cite web|title=Methylprednisolone|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=929&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States, a course of treatment typically costs less than $25.TarasconPP2015, page 202
=[[Metoclopramide]]=
The wholesale cost in the developing world as of 2014 is {{US$}}0.003 to {{US$}}0.08 per pill.{{cite web|title=Metoclopramide HCL|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=515&searchYear=2014|website=International Drug Price Indicator Guide|access-date=23 August 2016}} In the United States a month worth of medication is generally less than {{US$}}25.TarasconPP2015, page 262
=[[Miconazole]]=
The wholesale cost in the developing world is about 0.23 to US$0.60 for a 30 gram tube.{{cite web|title=Miconazole Nitrate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=527&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a course of treatment costs less than US$25.TarasconPP2015, page 180
=[[Midazolam]]=
Midazolam is available as a generic medication and is not very expensive.TarasconPP2015, page 21 The wholesale cost in the developing world of a vial is about US$0.35.{{cite web|title=Midazolam|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1316&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=29 August 2015}}
==Cost==
Midazolam is available as a generic medication and is not very expensive. The wholesale price of a vial is about US$0.35.
=[[Minocycline]]=
A month supply in the United Kingdom costs the NHS about 14 £ as of 2019.BNF76, page 556 In the United States the wholesale cost of this amount is about US$12.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
==Cost==
A month supply in the United Kingdom costs the NHS about 14 £ as of 2019. In the United States the wholesale cost of this amount is about US$12.
In October 2015, a bottle of 30 of tablets of one brand cost $1,040.41 wholesale.{{cite web | url=http://www.advfn.com/news_Pharmacys-Sales-Tactics-Disclosed_69068448.html | title=Pharmacy's Sales Tactics Disclosed | work=Dow Jones News | date=28 October 2015 | accessdate=1 November 2015 | author1=Rockoff, Jonathan D. | author2=Whalen, Jeanne}} Expensive medications like this were sold through the specialty pharmacy Philidor by Valeant Pharmaceuticals International Inc in a 2015 controversial legal tangle involving both companies.{{cite web | url=https://www.wsj.com/articles/valeant-countersues-r-o-pharmacy-1446176996 | title=Valeant Countersues R&O Pharmacy Billing dispute draws attention to drug maker’s work with specialty pharmacies | date=29 October 2015 |newspaper=The Wall Street Journal | author=Rapoport, Michael}}{{cite news |title=Alexion to Buy Synageva for $8.4 Billion |newspaper=The Wall Street Journal |date=May 6, 2015 |url=https://www.wsj.com/articles/alexion-to-buy-synageva-in-8-4-billion-biotech-deal-1430911447 |first=Chelsey |last=Dulaney}}
=[[Mirabegron]]=
A month supply in the United Kingdom costs the NHS about £29 as of 2019.BNF76, page 763 In the United States the wholesale cost of this amount is about 369 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Mirtazapine]]=
In the United States the wholesale cost as of 2018 is about US$3 per month.{{cite web |title=NADAC as of 2018-11-21 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-11-21/j5j5-fxwa |website=Centers for Medicare and Medicaid Services |accessdate=21 November 2018 }} In the United Kingdom a month supply costs less than £20 per month.BNF74, page 354
=[[Misoprostol]]=
The wholesale cost in the developing world is about 0.36 to 2.00 USD a dose.{{cite web|title=Misoprostol|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1154&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=20 December 2015}} A month's supply to treat stomach ulcers in the United States is between 100 and 200 USD.TarasconPP2015, page 271 The same costs between 30 and 55 EUR in Europe.{{cite web|title=DocMorris - Cytotec 200 µg Tabletten |url=https://www.docmorris.de/cytotec-200-g-tabletten/01559347?sc=PKV |accessdate=20 May 2016 |date=6 May 2016 }}
=[[Modafinil]]=
In the United Kingdom it costs the NHS about £105.21 a month as of 2018.BNF74, page 468 In the United States the wholesale cost per month is about US$34.20 as of 2018.{{cite web |title=NADAC as of 2018-06-13 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-06-13/kywb-5uhe |website=Centers for Medicare and Medicaid Services |accessdate=24 June 2018 }}
=[[Mometasone/formoterol]]=
In the United States the wholesale cost of a puffer is about 202 USD as of 2019.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Monochloramine]]=
The wholesale cost in the developing world is about {{US$|link=yes}}13.80 to {{US$}}18.41 per 500 grams.{{cite web|title=Chloramine |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=143&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Montelukast]]=
In the United States, the wholesale cost per dose is less than 0.15 USD as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}} In the United Kingdom, it costs the NHS about a pound per dose.BNF76, page 269 In 2016, it was the 23rd most prescribed medication in the United States, with more than 25 million prescriptions.{{cite web |title=The Top 300 of 2019 |url=https://clincalc.com/DrugStats/Top300Drugs.aspx |website=clincalc.com |accessdate=22 December 2018}}
=[[Moxifloxacin]]=
The wholesale cost in the developing world is US$0.45–2.70 per day, as of 2015.{{cite web|title=Single Drug Information|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1508&searchYear=2015|website=International Medical Products Price Guide|accessdate=9 December 2017}} In the United States, as of 2017, the wholesale cost is about $4.00 per day.{{cite web|title=NADAC as of 2017-12-06|url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2017-12-06/8h2n-xgjm|website=Centers for Medicare and Medicaid Services|accessdate=10 December 2017|language=en}}
=[[Mumps vaccine]]=
The wholesale cost in the developing world of the version that includes measles and rubella is 0.24 USD per dose as of 2014.{{cite web|title=Vaccine, Measles-Mumps-rubella|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=795&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2015}}
=[[Mupirocin]]=
The wholesale cost in the developing world is about US$2.10 for a 15 g tube.{{cite web|title=Mupirocin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1464&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States, a course of treatment costs $25 to $50.TarasconPP2015, page 178
=[[Mycophenolic acid]]=
In the United Kingdom it costs the NHS about £14 per month.BNF76, pages 826–827 In the United States this amount is about US$114.{{cite web |title=Mycophenolate mofetil Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/mycophenolate-mofetil |website=Drugs.com |accessdate=29 October 2019 |language=en}}
=[[NPH insulin]]=
The wholesale cost in the developing world is about US$2.23–10.35 per 1,000 iu of NPH insulin.{{cite web|title=Insulin, Neutral Soluble|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=431&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom 1,000 iu of NPH insulin costs the NHS £7.48 while in the United States this amount costs about US$134.00.BNF69, pages 464–472{{cite web|title=NADAC as of 2016-12-07 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services|accessdate=17 January 2017}}
=[[Nadolol]]=
A month supply in the United Kingdom costs the NHS about £6 as of 2019.BNF76, page 148 In the United States the wholesale cost of this amount is about $US 52 .{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Naloxone]]=
Its wholesale price in developing countries is between $0.50 and $5.30 per dose.{{cite web|title=Naloxone HCL|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=537&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=13 August 2015}} Vials of naloxone are not very expensive (less than $25) in the United States.TarasconPP2014, page 174 However, the price for a package of two auto-injectors in the US has increased from $690 in 2014 to $4,500 in 2016.{{cite journal | title =Perspective: The Rising Price of Naloxone — Risks to Efforts to Stem Overdose Deaths | journal =N Engl J Med | date =December 8, 2016 | authors =Ravi Gupta, Nilay D. Shah, and Joseph S. Ross | volume =375 | issue =23 | pages =2213–2215 | doi =10.1056/NEJMp1609578 | pmid = 27959694| pmc = }} The 2018 price for the NHS in the United Kingdom is about £5 per dose.BNF74, page 1260 In Australia, a single dose without prescription costs AU$20 while with a prescription five doses is AU$40.{{cite web |last1=Coulter |first1=Ellen |title=This drug can temporarily reverse an opioid overdose. So why aren't people using it? |url=https://www.abc.net.au/news/2019-08-27/naloxone-can-stop-an-overdose-why-arent-people-using-it/11448540 |website=ABC News |accessdate=28 August 2019 |date=27 August 2019}}
=[[Naltrexone]]=
As of 2019, the wholesale cost of tablets is about US$0.78 per day in the United States.{{cite web |title=NADAC as of 2019-07-17 {{!}} Data.Medicaid.gov |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-07-17/p2wi-peat |website=Centers for Medicare and Medicaid Services |accessdate=16 July 2019 |language=en}} The extended-release injections cost about $1,267 per month ($41.20 per day).
=[[Naproxen]]=
In the United Kingdom, it cost about £0.15 per dose in 2017.BNF74, pages 1048–1049 In the United States, the wholesale cost per dose is less than US$0.10 as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |access-date=22 December 2018}}
=[[Natamycin]]=
The wholesale cost in the developing world is between US$92.90 and 126.72 per 5-ml bottle as of 2015.{{cite web|title=Single Drug Information|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1606&searchYear=2015|website=International Medical Products Price Guide|accessdate=9 December 2017}}
=[[Nebivolol]]=
A month supply in the United Kingdom costs the NHS about 0.89 £ as of 2019.BNF76, page 154 In the United States the wholesale cost of this amount is about US$128.00.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Neomycin/polymyxin B/hydrocortisone]]=
In the United Kingdom a 10 ml bottle costs the NHS about £7.45 as of 2019.BNF76, page 1164 In the United States the wholesale cost of this amount is about 50 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=Cost=
In David Lazarus' February 4, 2016 LA Times column, a pharmacist recalled a 10 milliliter vial of the drug selling for around $10 in the early 2010s. In 2015, the price was $100, and in 2016, it reportedly was selling for $195. A generic version is priced at $144.{{cite web|url=http://www.latimes.com/business/la-fi-lazarus-shkreli-20160204-column.html |title=Martin Shkreli isn't alone in ripping off patients with crazy drug prices |publisher=latimes.com |first=David|last=Lazarus|date=2016-02-04 |accessdate=2016-02-05}}
=[[Neostigmine]]=
The wholesale cost in the developing world is about US$0.18–2.6 per dose.{{cite web|title=Neostigmine Methylsulfate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=545&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Nepafenac]]=
==Cost==
The average yearly cost for a Medicare Part D patient for Ilevro is $94. The estimated per unit price in the United States for Nevanac is $88.93.{{cite web|title=Nevanac Prices, Coupons and Patient Assistance Programs|url=https://www.drugs.com/price-guide/nevanac|website=Drugs.com|accessdate=October 31, 2017}} For Ilevro, the per unit price for the 1.7 mL bottle averages $156.89 and the per unit price for the 3 mL bottle averages $88.91.{{cite web|title=Ilevro Prices, Coupons and Patient Assistance Programs|url=https://www.drugs.com/price-guide/ilevro|website=Drugs.com|accessdate=October 31, 2017}} Average price for both drugs is similar.
=[[Nevirapine]]=
The wholesale cost in the developing world is US$2.16 to $16.62 per month as of 2014.{{cite web|title=Nevirapine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=547&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=3 December 2016}} As of 2015, the cost for a typical month of medication in the United States was more than $200.TarasconPP2015, page 63
=[[Niclosamide]]=
The wholesale cost in the developing world is about 0.24 USD for a course of treatment.{{cite web|title=Niclosamide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=548&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=1 December 2016}}
=[[Nifedipine]]=
The wholesale price in the developing world for the slow-release form is approximately US$1.90–3.80 per month.{{cite web|title=Nifedipine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=934&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=25 December 2015}} In the United States, it costs approximately $40–60 per month, depending on the dose.{{cite web|title=Nifedipine|url=https://www.drugs.com/monograph/nifedipine.html|publisher=The American Society of Health-System Pharmacists|accessdate=Sep 17, 2019
=[[Nilotinib]]=
In the United Kingdom it costs the NHS £2,432.85 per month as of 2018.BNF76, page 960 In the United States this amount costs US$14,367.94 as of 2019.{{cite web |title=Tasigna Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/tasigna |website=Drugs.com |accessdate=14 November 2019 |language=en}}
In the United Kingdom it costs the NHS £2,432.85 per month as of 2018. In the United States this amount costs US$14,367.94 as of 2019.
=[[Nitrofurantoin]]=
The wholesale cost in the developing world is between 0.10 and 9.20 USD for a course of treatment.{{cite web|title=Nitrofurantoin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=554&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=31 August 2015}} In the United States, the wholesale cost is about 8 USD for this amount as of 2018.{{cite web |title=NADAC as of 2018-09-12 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-09-12/df3u-3kse |website=Centers for Medicare and Medicaid Services |accessdate=26 June 2018 |language=en}}
==Cost==
The wholesale cost in the developing world is between 0.10 and 9.20 USD for a course of treatment. In the United States, the wholesale cost is about 8 USD for this amount as of 2018.
The cost of the liquid formulation of nitrofurantoin in the U.S. became controversial after a 400% price increase. There are two manufacturers of the liquid formulation in the U.S., Casper Pharma and Nostrum Laboratories. In 2018, Casper increased their price to $2,800. In response to Casper, Nostrum increased their price from $474.75 to $2,392. In the U.K., a slightly larger bottle costs £446.95. In an interview with the Financial Times, Nirmal Mulye, Nostrum chief executive, said that there was a "moral requirement to sell the product at the highest price." He defended Martin Shkreli, and said, "This is a capitalist economy and if you can’t make money you can’t stay in business." Mulye also attacked the U.S. Food and Drug Administration as "incompetent and corrupt." There is a shortage of liquid nitrofurantoin, because the FDA implemented new rules on impurities, he said. Mulye dismissed the new rules on impurities as a "piece of nonsense."[https://www.ft.com/content/48b0ce2c-b544-11e8-bbc3-ccd7de085ffe Pharma chief defends 400% drug price rise as a ‘moral requirement’], David Crow, Financial Times, Sept. 11, 2018
FDA commissioner Scott Gottlieb tweeted a response: "[T]here’s no moral imperative to price gouge and take advantage of patients. FDA will continue to promote competition so speculators and those with no regard to public health consequences can’t take advantage of patients who need medicine."{{cite news |last1=Hiltzik |first1=Michael |title=Drug executive: It's a 'moral requirement' to charge patients the highest price |url=http://www.latimes.com/business/hiltzik/la-fi-hiltzik-drug-prices-20180911-story.html |accessdate=14 September 2018 |work=latimes.com}}
=[[Nitroglycerin (medication)]]=
The wholesale cost in the developing world as of 2014, was {{US$|0.06{{ndash}}0.22|link = yes}} per dose by mouth.{{cite web|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=379&searchYear=2014| date = 2014 | title=Nitroglycerin |accessdate=8 December 2016}}
=[[Nivolumab]]=
In the United Kingdom it costs the NHS about £5266 a month as of 2018.BNF76, page 852 In the United States this amount costs about US$13,556 as of 2019,{{cite web |title=Opdivo Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/opdivo |website=Drugs.com |access-date=14 November 2019 |language=en}} while in China it is about US$7,000.{{Cite web|url=https://endpts.com/bristol-myers-will-sell-opdivo-in-china-at-half-of-us-cost-setting-precedent-for-checkpoint-wave-report/|title=Bristol-Myers will sell Opdivo in China at half of US cost, setting precedent for checkpoint wave — report|website=Endpoints News|language=en|access-date=2019-09-09}}
=[[Norepinephrine (medication)]]=
The wholesale cost in the developing world as of 2015 is about 0.42 USD per vial of four milligrams.{{cite web|title=Norepinephrine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=558&searchYear=2015|website=mshpriceguide.org|accessdate=26 March 2017}} In the United Kingdom this amount costs the NHS about 4.40 pounds.BNF69, page 145
=[[Norethisterone enanthate]]=
The wholesale cost in the developing world is about US$1.04–7.99 per 200 mg vial.{{cite web|title=Norethisterone|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=561&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Nortriptyline]]=
Nortriptyline was approved for medical use in the United States in 1964.{{cite web |title=Nortriptyline Hydrochloride Monograph for Professionals |url=https://www.drugs.com/monograph/nortriptyline-hydrochloride.html |website=Drugs.com |publisher=American Society of Health-System Pharmacists |accessdate=22 March 2019 |language=en}} A month supply in the United Kingdom costs the NHS about £25.00 as of 2019.BNF76, page 374 In the United States the wholesale cost of this amount is about US$4.20.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Nystatin]]=
The wholesale price of the cream in the developing world is about US$0.70 per 30 gram tube.{{cite web|title=Nystatin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=568&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=2016-01-27}} In the United States a course of treatment costs less than US$25.TarasconPP2015, page 180
=[[Ofloxacin]]=
The wholesale cost in the developing world is about US$3.27 per month.{{cite web|title=Ofloxacin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=969&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States, a course of treatment costs about $50–100.TarasconPP2015, page 101
=[[Olanzapine]]=
In the United States, the wholesale cost is less than {{USD}}0.25 per dose as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}}
=[[Olmesartan]]=
A month supply in the United Kingdom costs the NHS less than 2.50 £ as of 2019.BNF76, page 177 In the United States the wholesale cost of this amount is less than US$5.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Olmesartan/hydrochlorothiazide]]=
A month supply in the United Kingdom costs the NHS about 13 £ as of 2019.BNF76, pages 177–178 In the United States the wholesale cost of this amount is about US$6.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Olopatadine]]=
A 5 milliliter bottle of the eye drops in the United Kingdom costs the NHS less than £5 as of 2019.BNF76, page 1126 In the United States the wholesale cost of this amount is about US$12.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Omega-3 acid ethyl esters]]=
A one-month supply in the United Kingdom costs the NHS about £6 as of 2019.BNF76, pages 206–207 In the United States the wholesale cost of this amount is about 7.50 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 |language=en}}
=[[Omeprazole]]=
The wholesale cost in the developing world as of 2014 is US$0.01 to US$0.07 per dose.{{cite web |title=Omeprazole |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=571&searchYear=2014 |website=International Drug Price Indicator Guide |access-date=October 21, 2018 }} In the United States, it costs on average US$0.50 per pill.{{cite web |title=NADAC as of 2016-11-16 Data.Medicaid.gov |url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-11-16/dyki-3gk4 |publisher=Centers for Medicare and Medicaid Services |access-date=October 21, 2018}}
=[[Ondansetron]]=
The wholesale cost of the injectable form in the developing world is about {{US$}}0.10 to {{US$}}0.76 per dose.{{cite web|title=Ondansetron|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1040&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=26 January 2016}} In the United States it costs about {{US$}}1.37 per tablet.{{cite web|title=Ondansetron Hydrochloride|url=https://www.drugs.com/monograph/ondansetron-hydrochloride.html|publisher=The American Society of Health-System Pharmacists|accessdate=February 11, 2017}}
=[[Oral rehydration therapy]]=
The wholesale cost in the developing world of a package to mix with a liter of water is US$0.03 to 0.20.{{cite web|title=Oral Rehydration Salts|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=572&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Oseltamivir]]=
{{As of |2014}} the wholesale cost in the developing world was about {{US$|4.27}} per day.{{cite web|title=Oseltamivir|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1611&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=30 July 2016}} The wholesale cost for a course of treatment in the United States is about {{US$|54.00}} as of 2019.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Oxaliplatin]]=
The wholesale cost in the developing world is 8.74 to 125.43 USD a vial.{{cite web|title=Oxaliplatin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1554&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom it costs the NHS 299.50 pounds per 100 mg dose.BNF69, page 605
=[[Oxcarbazepine]]=
A month supply in the United Kingdom costs the NHS about 6.50 £ as of 2019.BNF76, pages 319–320 In the United States the wholesale cost of this amount is about US$7.15.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Oxybutynin]]=
A month supply in the United Kingdom costs the NHS less than GB£3 per month as of 2019.BNF76 In the United States the wholesale cost of this amount is about US$14.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Oxycodone]]=
In the United States, the wholesale cost per dose is less than US$0.30 as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}}
=[[Oxytocin (medication)]]=
{{As of|2014}}, the wholesale cost in the developing world is US$0.10 to 0.56 per dose.{{cite web | title = Oxytocin | url = http://mshpriceguide.org/en/single-drug-information/?DMFId=580&searchYear=2014 | website = International Drug Price Indicator Guide | access-date = 20 December 2015 }}
=[[Paclitaxel]]=
The wholesale cost in the developing world is about US$7.06–13.48 per 100 mg vial.{{cite web|title=Paclitaxel|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1555&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} This amount in the United Kingdom costs the NHS about 66.85 GBP.BNF69, page 623
==Cost==
{{as of|2006}}, the cost to the NHS per patient in early breast cancer, assuming four cycles of treatment, was about £4000 (approx. $6000).{{cite web|title=NICE Guidance TA108|url=http://guidance.nice.org.uk/TA108/guidance/pdf/English}}
=[[Pancreatic enzymes (medication)]]=
In the United Kingdom a typical month's supply costs the NHS about £12.93 to £47.55 as of 2019.BNF76, pages 96–97 In the United States the wholesale cost of this amount is about {{US$}}300 to {{US$}}900.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Pantoprazole]]=
As of 2018, the wholesale cost of the pills in the United States is less than US$0.10 per dose.{{cite web |title=NADAC as of 2018-10-24 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-10-24/95jf-evmp |website=Centers for Medicare and Medicaid Services |access-date=28 October 2018 |language=en}} In the United Kingdom, this amount costs less than 0.05 pounds, while the intravenous formulation costs about 5 pounds per dose.BNF74, page 79
=[[Paracetamol]]=
The wholesale price in the developing world is less than {{US$|0.01}} per dose.{{cite web|title=Paracetamol|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=592&searchYear=2014|access-date=11 January 2016}} In the United States, it costs about {{US$|0.04}} per dose.{{cite web|title=Acetaminophen prices, coupons and patient assistance programs|url=https://www.drugs.com/price-guide/acetaminophen|access-date=19 February 2016}}
==Cost==
The wholesale price in the developing world is less than US$0.01 per dose. In the United States, it costs about US$0.04 per dose.
In Europe, prices differ from country to country; low-cost prices for 10 doses could reach €0.54 in Portugal, €0.91 in France and €1.97 in Germany.{{cite web|url=http://www.linternaute.com/acheter/chiffres/07/prix-europe/7.shtml |title=Les prix en Europe - La boîte paracétamol 10 comprimés (générique) |language=fr|publisher=Linternaute.com |date= |access-date=2018-10-10}}
=[[Paroxetine]]=
A month supply in the United Kingdom costs the NHS about £1.10 per month as of 2019.BNF76, page 363 In the United States the wholesale cost of this amount is about {{US$}}2.40.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 |language=en}}
==Society and culture==
A month supply in the United Kingdom costs the NHS about 1.10 £ per month as of 2019. In the United States the wholesale cost of this amount is about US$2.40.
=[[Pegaspargase]]=
In the United States it costs about $US17,800 per 3750 units vial.{{cite web |title=Oncaspar Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/oncaspar |website=Drugs.com |accessdate=11 October 2019 |language=en}}
=[[Penicillamine]]=
The wholesale cost in the developing world is about US$0.55 to $1.20 a dose.{{cite web|title=Penicillamine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=595&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} A month supply in the United Kingdom costs the NHS about 178 £ as of 2019.BNF76, page 1064 In the United States the costs of the medication increased from about 500 USD to 24,000 USD per month in 2016.{{cite news |last1=Petersen |first1=Melody |title=How 4 drug companies rapidly raised prices on life-saving drugs |url=https://www.latimes.com/business/la-fi-senate-drug-price-study-20161221-story.html |accessdate=27 March 2019 |work=latimes.com}}
=[[Pentavalent vaccine]]=
==Society and culture==
In November 2010, the public-private consortium GAVI announced that the cost of the pentavalent vaccine for emerging-market countries had dropped below $3.00 USD per dose.{{cite web|url=https://www.gavi.org/library/news/press-releases/2010/price-of-life-saving-vaccine-expected-to-drop-significantly-in-2011/|website=GAVI|access-date=3 July 2018|title=Price of life-saving vaccine expected to drop significantly in 2011|date=26 November 2010}}
In contrast, a typical wholesale cost of a DTPw-HepB-Hib pentavalent vaccine was about $15.40 USD in 2014.{{cite web|title=Vaccine, Pentavalent|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1556&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=6 December 2015}}
=[[Peritoneal dialysis]]=
The cost of dialysis solution in the developing world is about US$6.77–7.30 per two-liter bag or about $12,000 per year.{{cite web|title=Dialysis Sol. Peritoneal W/ Dextrose |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=249&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}{{cite book|last1=Ronco|first1=Claudio|last2=Crepaldi|first2=Carlo|last3=Cruz|first3=Dinna N.|title=Peritoneal Dialysis: From Basic Concepts to Clinical Excellence|date=2009|publisher=Karger Medical and Scientific Publishers|isbn=9783805592024|page=244|url=https://books.google.ca/books?id=rA8Xo5xEVeoC&pg=PA244|language=en|url-status=live|archiveurl=https://web.archive.org/web/20170113133606/https://books.google.ca/books?id=rA8Xo5xEVeoC&pg=PA244|archivedate=2017-01-13}} In the United States peritoneal dialysis costs the government about $53,400 per person per year.{{cite book|last1=Barkoudah|first1=Ebrahim|title=Volume 5, Issue 4, An Issue of Hospital Medicine Clinics|date=2016|publisher=Elsevier Health Sciences|isbn=9780323463164|chapter-url=https://books.google.ca/books?id=4NsqDQAAQBAJ&pg=PT13|language=en|chapter=Dialysis Initiation During the Hospital Stay}}
=[[Permethrin]]=
The wholesale cost in the developing world is about US$0.02 to US$0.06 per gram.{{cite web|title=Permethrin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1615&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United States, a course of treatment costs US$25 to US$50, and it is available over the counter.TarasconPP2015, page 182
=[[Pertussis vaccine]]=
A version that also includes tetanus, diphtheria, polio, and Hib vaccine is available wholesale in the developing world at a cost of 15.41 USD per dose as of 2014.{{cite web|title=Vaccine, Pentavalent|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1556&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2015}}
=[[Phenoxymethylpenicillin]]=
The wholesale cost in the developing world is about US$0.05–0.96 per day.{{cite web|title=Penicillin, Phenoxymethyl|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=602&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a course of treatment costs less than $25.TarasconPP2015, page 95
=[[Phentermine]]=
The wholesale cost of a month supply in the United States is about US$2.55.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Phenytoin]]=
Phenytoin is available as a generic medication and usually not too expensive.TarasonPP2013, page 294 The wholesale cost in the developing world is between US$0.003 and US$0.15 per dose.{{cite web|title=Phenytoin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=628&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=23 August 2015}} A month of treatment is about US$30 in the United States.{{cite web|title=Phenytoin|url=https://www.drugs.com/monograph/phenytoin.html|publisher=The American Society of Health-System Pharmacists|accessdate=Aug 22, 2015}}
==Cost==
Phenytoin is available as a generic medication and usually not too expensive. Wholesale it costs between US$0.003 and US$0.15 per dose. A month of treatment is about US$30 in the United States.
After Pfizer's sale of the UK marketing licence to Flynn Pharma, the price of a 28-pack of 25 mg phenytoin sodium capsules marked Epanutin rose from 66p (about $0.88) to £15.74 (about $25.06). Capsules of other strengths also went up in price by the same factor—2384%,[https://www.telegraph.co.uk/health/healthnews/9604683/Pharma-firm-hikes-cost-of-epilepsy-drug-24-times.html "Pharma firm hikes cost of epilepsy drug 24 times"], Stephen Adams, Medical Correspondent, Daily Telegraph, London, 12 October 2012 {{webarchive|url=https://web.archive.org/web/20140609234150/http://www.telegraph.co.uk/health/healthnews/9604683/Pharma-firm-hikes-cost-of-epilepsy-drug-24-times.html |date=9 June 2014 }}. Accessed 13 May 2014. costing the UK's National Health Service an extra £43 million (about $68.44 million) a year.[http://www.pulsetoday.co.uk/commissioning/commissioning-topics/prescribing/price-of-anti-epilepsy-drug-rockets/20000936.article#.U3Jez6G-ZQI "Price of anti-epilepsy drug rockets"], Mark Gould, Pulse, London, 21 November 2012 {{webarchive|url=https://web.archive.org/web/20121128130259/http://www.pulsetoday.co.uk/commissioning/commissioning-topics/prescribing/price-of-anti-epilepsy-drug-rockets/20000936.article |date=28 November 2012 }}. Accessed 13 May 2014. The companies were referred to the Competition and Markets Authority who found that they had exploited their dominant position in the market to charge "excessive and unfair" prices.{{cite news|last1=White|first1=Michael|title=Pharma market abuse isn't picked up fast enough|url=http://www.hsj.co.uk/comment/pharma-market-abuse-isnt-picked-up-fast-enough/5089545.article |accessdate=6 October 2015 |work=Health Service Journal |date=12 August 2015}}
The Competition and Markets Authority (CMA) imposed a record £84.2 million fine on the manufacturer Pfizer, and a £5.2 million fine on the distributor Flynn Pharma and ordered the companies to reduce their prices.{{Cite press release |url=https://www.gov.uk/government/news/cma-fines-pfizer-and-flynn-90-million-for-drug-price-hike-to-nhs|title=CMA fines Pfizer and Flynn £90 million for drug price hike to NHS |publisher=www.gov.uk |access-date=2016-12-07 }}
=[[Phytomenadione]]=
The wholesale cost in the developing world is about 0.11 to 1.27 USD for a 10 mg vial.{{cite web|title=Vitamin K1|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=839&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United States a course of treatment costs less than 25 USD.TarasconPP2015, page 229
=[[Pilocarpine]]=
The wholesale cost in the developing world is about US$1.61–4.88 per 10 ml bottle.{{cite web|title=Pilocarpine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=633&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United States a month of the drops costs less than $25 as of 2015.TarasconPP2015, pages 254, 412 It is one of the lowest cost medications for glaucoma.{{cite book |last1=Schwab |first1=Larry |title=Eye Care in Developing Nations |date=2007 |publisher=CRC Press |isbn=9781840765229 |page=110 |url=https://books.google.ca/books?id=ngB2c6k6wLMC&pg=PA110 |language=en}}
==Cost==
=[[Pioglitazone]]=
A month supply in the United Kingdom costs the NHS less than £1 as of 2019.BNF76, page 694 In the United States the wholesale cost of this amount is about 3.20 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Piperacillin/tazobactam]]=
The wholesale cost in the developing world, as of 2015, is about US$11 per day.{{cite web|title=Single Drug Information|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1160&searchYear=2015|website=International Medical Products Price Guide|accessdate=10 December 2017}} In the United Kingdom, as of 2015, this amount costs the NHS about 38.70 pounds per day.BNF69, page 373
=[[Plazomicin]]=
The price of 10 days of treatment in the United States costs about US$6,600.{{cite web |title=Zemdri Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/zemdri |website=Drugs.com |accessdate=10 October 2019 }}
=[[Pneumococcal vaccine]]=
The wholesale cost in the developing world is about US$17 per dose as of 2014.{{cite web|title=Vaccine, Pneumococcal|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1248&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=6 December 2015}} In the United States it is between US$25 and US$100.TarasconPP2015, page 316
=[[Polio vaccine]]=
The wholesale cost in the developing world is about {{usd|0.25}} per dose for the oral form as of 2014.{{cite web|title=Vaccine, Polio|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=797&searchYear=2014|website=International Drug Price Indicator Guide|access-date=6 December 2015|df=dmy-all}} In the United States, it costs between $25 and $50 for the inactivated form.TarasonPP2015, page 316
==Cost==
The wholesale cost is about {{USD|0.25}} per dose for the oral form as of 2014. The Global Alliance for Vaccines and Immunization supplies the inactivated vaccine to developing countries for as little as {{Currency|0.75|EURO}} (about {{USD|{{To USD|0.75|EUR}}}}) per dose in 10-dose vials.{{cite web | title = Availability and price of inactivated polio vaccine | work = The Global Polio Eradication Initiative | url = http://www.polioeradication.org/Mediaroom/Newsstories(old)/Newsstories2013/tabid/488/iid/354/Default.aspx#sthash.jGhJ4YUB.dpuf }} In the United States, the inactivated form costs between $25 and $50.
=[[Polymyxin B]]=
In the United States it costs about US$17 per day.{{cite web |title=Polymyxin b Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/polymyxin-b |website=Drugs.com |accessdate=11 November 2019 |language=en|quote=Typical dose is about 20,000 units per kg * 70 = 1.4 million. So three vials per day.}}
=[[Polystyrene sulfonate]]=
A single dose in the United States costs about $US13.50 while 30 doses cost about $US64.00 as of 2019.{{cite web |title=Sodium polystyrene sulfonate Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/sodium-polystyrene-sulfonate |website=Drugs.com |accessdate=25 October 2019 |language=en}}
=[[Potassium chloride (medical use)]]=
The wholesale cost in the developing world is about 0.44 USD per 10 ml of 10% solution.{{cite web|title=Potassium Chloride|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=641&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom 10 ml of 15% solution costs the NHS about 0.48 pounds.BNF69, pages 680, 684
=[[Potassium permanganate]]=
The wholesale cost in the developing world is about US$0.01 per gram of powder.{{cite web|title=Potassium Permanganate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=644&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Potassium permanganate (medical use)]]=
The wholesale cost in the developing world is about 0.01 USD per g.{{cite web|title=Potassium Permanganate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=644&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom this amount costs the NHS about £1.33.BNF69, page 840
=[[Povidone-iodine]]=
The wholesale cost in the developing world is about {{US$}}3.30 to {{US$}}11.40 per liter of 10% solution.{{cite web|title=Povidone iodine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=678&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} This amount in the United Kingdom cost the NHS about £10.86.BNF69, page 840
=[[Pramipexole]]=
A month supply in the United Kingdom costs the NHS about £8.40 as of 2019.BNF76, pages 417–418 In the United States the wholesale cost of this amount is about 5 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Pravastatin]]=
In the United States the wholesale cost per dose is less than 0.20 USD as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}} In the United Kingdom it costs the NHS about a pound per dose.BNF76, page 202
=[[Praziquantel]]=
The wholesale cost in the developing world is about US$0.4–18.15 per day.{{cite web|title=Praziquantel |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=646&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a typical course of treatment costs $100–200.TarasconPP2015, page 54
=[[Prazosin]]=
A month supply in the United Kingdom costs about £3.50 as of 2019.BNF76, page 766 In the United States, the wholesale cost of this amount is about US$20.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Prednisone]]=
In the United States, the wholesale cost per dose was less than US$0.30 in 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}}
=[[Pregabalin]]=
In the US the wholesale costs is about US$11 per month as of October 2019.{{cite web |title=NADAC as of 2019-10-23 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-10-23/6maf-7ayz |website=Centers for Medicare and Medicaid Services |accessdate=October 27, 2019 |language=en}} While in the United Kingdom a similar dose costs the NHS about £6 as of 2018.BNF76, page 323
==Cost==
In the United States as of July 2019 the cost for generic pregabalin is US$0.17-0.22 per 150 mg capsule.{{cite web |title=Generic Lyrica launches at 97% discount to brand version|url=https://www.46brooklyn.com/news/2019/7/23/lyrica-goes-generic}}
Pfizer's main patent for Lyrica, for seizure disorders, in the UK expired in 2013. In November 2018 the Supreme Court of the United Kingdom ruled that Pfizer's second patent on the drug, for treatment of pain, was invalid because there was a lack of evidence for the conditions it covered – central and peripheral neuropathic pain. From October 2015 GPs were forced to change people from generic pregabalin to branded until the second patent ran out in July 2017. This cost the NHS £502 million.{{cite news |title=Pfizer's failed pregabalin patent appeal means NHS could reclaim £502m |url=http://www.pulsetoday.co.uk/clinical/clinical-specialties/prescribing/pfizers-failed-pregabalin-patent-appeal-means-nhs-could-reclaim-502m/20037790.article |accessdate=November 15, 2018 |publisher=Pulse |date=November 14, 2018 }}
=[[Primaquine]]=
The wholesale cost in the developing world is US$0.04–0.11 per day.{{cite web|title=Primaquine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=655&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=3 December 2016}}
=[[Primidone]]=
A month supply in the United Kingdom costs the NHS about 68.40 £ as of 2019.BNF76, page 332 In the United States the wholesale cost of this amount is about US$13.20.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Procaine benzylpenicillin]]=
The wholesale cost in the developing world is about US$0.09–0.18 per day.{{cite web|title=Penicillin, Procaine Benzyl|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=P599&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a course of treatment costs $100–200.TarasconPP2015, page 95
=[[Prochlorperazine]]=
A dose in the United Kingdom costs the NHS about £0.04 as of 2019.BNF76, pages 385–386 In the United States the wholesale cost of this amount is about US$0.24.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Proguanil]]=
The wholesale cost in the developing world is about US$0.10–0.50 per day.{{cite web|title=Proguanil|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=664&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Promethazine]]=
The wholesale cost of the by mouth formulation is less than US$0.20 per dose as of 2018.{{cite web |title=NADAC as of 2018-10-24 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-10-24/95jf-evmp |website=Centers for Medicare and Medicaid Services |accessdate=24 October 2018 |language=en}} In the United Kingdom this dose costs less than £0.25.BNF74, page 276
=[[Propofol]]=
The wholesale price in the developing world is between 0.61 and 8.50 USD per vial.{{cite web|title=Propofol|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=670&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=23 January 2016}}
=[[Propranolol]]=
The wholesale cost in the developing world is between {{US$}}0.24 and {{US$}}2.16 per month as of 2014.{{cite web|title=Propranolol|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=673&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=7 October 2019}} In the United States it costs about $15 per month at a typical dose.{{cite web | title = Propranolol hydrochloride | work = Monograph | url = https://www.drugs.com/monograph/propranolol-hydrochloride.html | publisher = The American Society of Health-System Pharmacists | accessdate = 1 January 2015}}
=[[Propylthiouracil]]=
The wholesale cost in the developing world is about 3.62 USD a month.{{cite web|title=Propylthiouracil|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=675&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom a month costs the NHS about 52.51 pounds.BNF69, page 493 In the United States the wholesale price is 38.34 USD per month.{{cite web|title=NADAC as of 2016-12-21 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-21/6ebu-k7ew|website=Centers for Medicare and Medicaid Services|accessdate=26 December 2016}}
=[[Protamine sulfate]]=
The wholesale cost in the developing world is about US$2.82–12.20 per vial.{{cite web|title=Protamine Sulfate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=676&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Pyrazinamide]]=
The wholesale cost in the developing world is about {{US$}}2.76 per month.{{cite web|title=Pyrazinamide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1617&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States, it costs about {{US$}}100 to {{US$}}200 per month.TarasconPP2015, page 49
=[[Pyridostigmine]]=
The wholesale cost in the developing world is about US$7.17–65.93 a month.{{cite web|title=Pyridostigmine Bromide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=684&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States it costs about US$25–50 per month.TarasconPP2015, page 339
=[[Pyridoxine]]=
The wholesale cost in the developing world is about US$0.59–3.54 per month.{{cite web|title=Vitamin B6|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=828&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Quetiapine]]=
In the United States, the wholesale cost is about {{USD}}12 per month as of 2017.{{cite web|title=NADAC as of 2017-03-22|url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2017-03-22/9q7x-utx9|publisher=Centers for Medicare and Medicaid Services|access-date=26 March 2017|df=}} In the United Kingdom, a month's supply costs the NHS about £60 as of 2017.BNF74, page 383
==Cost==
In the United States as of 2015, the branded extended-release 400 mg pills cost between {{USD}}9.68 and {{USD}}23.16 each.{{cite news|last1=Langreth|first1=Robert| name-list-style = vanc |title=Decoding Big Pharma's Secret Drug Pricing Practices|url=https://www.bloomberg.com/graphics/2016-drug-prices/|access-date=15 July 2016|publisher=Bloomberg|date=June 29, 2016}} In 2017, the short-acting version had a wholesale cost of about {{USD}}12 per month.
In the United Kingdom, a month's supply, as of 2017, costs the NHS approximately £107.45. This is following an increase of 30 to 70 fold in 2017/2018.{{cite news |title=NHS hit by seven-fold increase in bill for certain drugs |url=https://www.hsj.co.uk/finance-and-efficiency/nhs-hit-by-seven-fold-increase-in-bill-for-certain-drugs/7022614.article |access-date=29 August 2018 |publisher=Health Service Journal |date=8 June 2018}}
=[[Quinapril]]=
In the United States the wholesale cost of this amount is about US$3.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Quinine]]=
The wholesale price in the developing world is about US$1.70 to $3.40 per course of treatment.{{cite web|title=Quinine Sulfate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=690&searchYear=2014|website=International Drug Price Indicator Guide|access-date=12 January 2016}} In the United States a course of treatment is more than $200.TarasconPP2015, page 47
=[[Rabeprazole]]=
A month supply in the United Kingdom costs the NHS about £1 as of 2019.BNF76, page 82 In the United States the wholesale cost of this amount is about 11 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Rabies vaccine]]=
The wholesale cost in the developing world is between 44 and 78 USD for a course of treatment as of 2014.{{cite web|title=Vaccine, Rabies|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=799&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=6 December 2015}} In the United States a course of rabies vaccine is more than 750 USD.{{cite web|last1=Shlim|first1=David|title=Perspectives: Intradermal Rabies Preexposure Immunization|url=https://wwwnc.cdc.gov/travel/yellowbook/2020/travel-related-infectious-diseases/perspectives-alternative-approaches-to-rabies-immunization|accessdate=26 December 2019|date=June 24, 2019|website=Centers for Disease Control and Prevention (CDC)}}
=[[Raloxifene]]=
In the United States the wholesale cost of this amount is about 16 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Raltegravir]]=
The wholesale cost in the developing world is about 50 USD per month.{{cite web|title=Single Drug Information|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1432&searchYear=2015|website=International Medical Products Price Guide|accessdate=9 December 2017}} In the United Kingdom it costs the NHS about 472.00 pounds per month.BNF69, page 429
=[[Ramipril]]=
A month supply in the United Kingdom costs the NHS less than £1 as of 2019.BNF76, pages 172–173 In the United States, the wholesale cost of this amount is about US$2.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Ranitidine]]=
The 2015 wholesale price in the developing world was about US$0.01–0.05 per pill.{{cite web|title=Ranitidine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=693&searchYear=2014|website=International Drug Price Indicator Guide|access-date=1 December 2015|df=dmy-all}} In the United States it is about $0.05 per dose.{{cite web|title=Ranitidine Hydrochloride Monograph|url=https://www.drugs.com/monograph/ranitidine-hydrochloride.html|publisher=The American Society of Health-System Pharmacists|access-date=1 December 2015}}
=[[Ranolazine]]=
A month supply in the United Kingdom costs the NHS about 50 £ as of 2019.BNF76, page 210 In the United States the wholesale cost of this amount is about 343 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 |language=en}}
=[[Regular insulin]]=
The wholesale cost in the developing world is about US$2.39–10.61 per 1,000 iu of regular insulin.{{cite web|title=Insulin, Neutral Soluble|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=431&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom 1,000 iu costs the NHS £7.48, while in the United States this amount is about $134.00.BNF69, pages 464-472{{cite web|title=NADAC as of 2016-12-07 {{!}} Data.Medicaid.gov|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-12-07/ry9m-tx78|website=Centers for Medicare and Medicaid Services|accessdate=17 January 2017|df=dmy-all}}
=[[Retinol]]=
The wholesale cost in the developing world is about US$0.02–0.30 per 50,000 units.{{cite web|title=Vitamin A|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=812&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United States it is not very expensive.TarasconPP2015, page 230
=[[Rifabutin]]=
The wholesale cost in the developing world is about US$30 a month.{{cite web|title=Rifabutin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1099&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a month of treatment is more than $200.TarasconPP2015, page 50
=[[Rifampicin]]=
The wholesale cost in the developing world is about US$3.90 a month.{{cite web|title=Rifampicin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1558&searchYear=2014|website=International Drug Price Indicator Guide|access-date=24 August 2015}} In the United States a month of treatment is about $120.{{cite web|title=Rifampin|url=https://www.drugs.com/monograph/rifampin.html|publisher=The American Society of Health-System Pharmacists|access-date=Aug 1, 2015}}TarasconPP2014, page 39
=[[Rifampicin/isoniazid/pyrazinamide]]=
The wholesale cost in the developing world is about 3.93 USD a month.{{cite web|title=Rifampicin + Isoniazid + Pyrazinamide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1331&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom a month of treatment costs the NHS about 39.51 pounds.BNF69, page 403
=[[Ringer's lactate solution]]=
The wholesale cost in the developing world is about {{US$}}0.60 to {{US$}}2.30 per liter.{{cite web|title=Sodium Lactate Compound|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=726&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Risperidone]]=
The wholesale price in the developing world is between {{US$}}0.01 and {{US$}}0.60 per day as of 2014.{{cite web|title=Risperidone|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1465&searchYear=2014|website=International Drug Price Indicator Guide|access-date=2 December 2015}} The cost for a typical month of medication in the United States is between {{US$}}100-200 as of 2015.TarasconPP2015, page XX
==History==
In 2003, Abbott (now AbbVie, Inc.) raised the price of a Norvir course from USD $1.71 per day to $8.57 per day, leading to claims of price gouging by patients' groups and some members of Congress.
=[[Rituximab]]=
The wholesale price in the developing world as of 2014 was US$148–496 per 100 mg.{{cite web|title=Rituximab|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1466&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=28 November 2015}} In the United Kingdom, the NHS paid approximately £182 per 100 mg in 2015.BNF69, page 638 In the United States, the average price paid was approximately $705 per 100 mg in 2014. The typical treatment for rheumatoid arthritis (1,000 mg IV dose, 2 weeks apart) in the United States would have been $14,100 a month in 2014.{{cite journal|title=Drugs for Rheumatoid Arthritis|journal=The Medical Letter|date=22 December 2014|volume=56|issue=1458|pages=127–32|url=http://secure.medicalletter.org/TML-article-1458a|url-access=subscription }}
=[[Rivaroxaban]]=
A month supply in the United Kingdom costs the NHS about £50 as of 2019.BNF76, pages 127–128 In the United States, the wholesale cost of this amount is about {{US$}}430.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 |language=en}}
==Society and culture==
Using rivaroxaban rather than warfarin costs 70 times more, according to Express Scripts Holding Co, the largest U.S. pharmacy benefits manager.{{Cite news |url= https://www.reuters.com/article/us-pharmaceuticals-bloodthinners-idUSKBN0U617320151223 |title= New blood thinner 'antidote' to help doctors move past warfarin |last=Bill Berkrot |date=December 23, 2015 |newspaper=Reuters}}
=[[Rizatriptan]]=
A dose in the United Kingdom costs the NHS about 3.10 £ as of 2019.BNF76, page 473 In the United States the wholesale cost of this amount is about US$0.73.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 |language=en}}
=[[Ropinirole]]=
A month supply in the United Kingdom costs the NHS about 34 £ per month as of 2019.BNF76, pages 419–420 In the United States the wholesale cost of this amount is about US$7.90.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Rosuvastatin]]=
In the United States, the wholesale cost per dose is less than {{US$|0.15}} {{as of| 2018|lc=yes}}.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services (CMS) |access-date=22 December 2018 }} In the United Kingdom, it costs the NHS about £0.65 per dose as of 2018.BNF76, page 203
==Marketing==
Annual cost to the UK National Health Service (NHS) in 2018 for 5-40mg rosuvastatin daily was £24-40, compared to £10-20 for 20-80mg simvastatin.{{Cite web|url=http://gmmmg.nhs.uk/docs/cost_comparison_charts.pdf|title=COST COMPARISON CHARTS|publisher=REGIONAL DRUG AND THERAPEUTICS CENTRE (NEWCASTLE)|date=August 2018}}
=[[Rotavirus vaccine]]=
The wholesale cost in the developing world is between US$6.96 and $20.66 per dose as of 2014.{{cite web|title=Vaccine, Rotavirus|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1473&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=6 December 2015}} In the United States it is more than US$200.TarasconPP2015, page 317
<<
=[[Rubella vaccine]]=
The wholesale cost of the MMR vaccine in the developing world is 0.24 USD per dose as of 2014.{{cite web|title=Vaccine, Measles-Mumps-rubella|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=795&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2015}} In the United States it costs between 50 and 100 USD.TarasconPP2015, page 315
=[[Salbutamol]]=
The wholesale cost in the developing world of an inhaler which contains 200 doses is between US$1.12 and US$2.64 as of 2014.{{cite web|title=Salbutamol|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=708&searchYear=2014|website=International Drug Price Indicator Guide|access-date=5 December 2015}} In the United States, it is between US$25 and US$50 for a typical month's supply.TarasconPP2015, page 448
==Cost==
File:IntWholesaleSalbutamol.pngThe wholesale cost of a 200-dose inhaler is between US$1.12 and US$2.64 in the developing world {{As of|2014|lc=y}} and {{GBP|1.50}} in the United Kingdom {{As of|2015|lc=y}}.BNF69, page 190 In the United States, a typical month's supply is between $25 and $50.TarasconPP2015, page XX
=[[Saline (medicine)]]=
The wholesale cost in the developing world is about US$0.60–4.20 per liter of normal saline.{{cite web|title=Sodium Chloride in Water|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=724&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
==Cost==
As of 2015 it is not available as a generic medication and is expensive.TarasconPP2015, page XX The wholesale cost is about 4.50 USD per day.
=[[Senna glycoside]]=
The wholesale cost in the developing world is about 0.01 USD per pill.{{cite web|title=Senna|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=717&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=11 August 2015}} Sennosides come from the group of plants Senna.{{cite book|last1=Navti|first1=Phyllis|title=Pharmacology for pharmacy and the health sciences : a patient-centred approach|date=2010|publisher=Oxford University Press|location=Oxford|isbn=9780199559824|page=337|url=https://books.google.ca/books?id=KVicAQAAQBAJ&pg=PA337}}
=[[Sertraline]]=
In the United States, the wholesale cost is about US$1.50 per month as of 2018.{{cite web|title=NADAC as of 2018-01-03|url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-01-03/v54n-gpyk|website=Centers for Medicare and Medicaid Services|access-date=7 January 2018}}
=[[Sildenafil]]=
As of 2018 in the United States the wholesale cost is less than US$1 per dose.{{cite web |title=NADAC as of 2018-11-21 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-11-21/j5j5-fxwa |website=Centers for Medicare and Medicaid Services |accessdate=24 November 2018 |language=en}}
=[[Silver sulfadiazine]]=
In the developing world the wholesale cost is between 0.004 and 0.072 USD per gram.{{cite web|title=Silver Sulfadiazine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=719&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=30 August 2016}} In the United States, a course of treatment is generally less than 25 USD.{{cite web |title=NADAC as of 2018-10-03 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-10-03/exd6-q7k7 |website=Centers for Medicare and Medicaid Services |accessdate=7 October 2018 |language=en}}{{cite web|url=https://www.goodrx.com/silver-sulfadiazine?form=tube-of-cream&dosage=50g-of-1%25|title=Silver Sulfadiazine Prices and Silver Sulfadiazine Coupons - GoodRx|date=October 7, 2018}}
=[[Simvastatin]]=
The wholesale cost in the developing world is US$0.01 to 0.12 per day {{as of|2014|lc=y}}.{{cite web|title=Simvastatin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1561&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=28 November 2015}} In the United States, it costs between US$0.50 and 1.00 per day.{{cite web|title=Simvastatin|url=https://www.drugs.com/monograph/simvastatin.html|publisher=The American Society of Health-System Pharmacists|accessdate=8 January 2015}}
==Society and culture==
In the UK in 2008, the typical per-patient cost to the NHS of simvastatin was about £1.50 per month.{{cite news |url=http://news.bbc.co.uk/1/hi/programmes/politics_show/7192271.stm |title=NHS overspends on statins |date=Jan 2008 }} (40 mg/day costs UK NHS £1.37/month in 2012{{cite web |url=http://www.cks.nhs.uk/diabetes_type_2/drugs_in_this_topic/scenario_managing_lipids/simvastatin_40mg_tablets |title=Simvastatin 40mg tablets }})
=[[Sitagliptin]]=
A month's supply in the United Kingdom costs the NHS about £33.26 per month as of 2019.BNF76, page 681 In the United States the wholesale cost of this amount is about US$405.00.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Sitagliptin/metformin]]=
A month supply in the United Kingdom costs the NHS about 33.26 £ as of 2019.BNF76, page 682 In the United States the wholesale cost of this amount is about 433 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
==Price==
A month supply in the United Kingdom costs the NHS about 33.26 £ as of 2019. In the United States the wholesale cost of this amount is about 433 USD. In Denmark 100 tablets (each 1,000 mg) cost over the counter in a pharmacy DKK 62.60 = US$ 9.40 = £7.50, thus a month supply in Denmark costs DKK 37.50 = US$ 5.70 = £ 4.50. The pharmacy buys wholesale at DKK 33.83 = US$ 5.11 = £4.10.{{cite web |title=Medicinpriser |url=https://www.medicinpriser.dk/Default.aspx?id=15&vnr=554406 |website=Medicinpriser |accessdate=17 June 2019 |language=da}}
=[[Sodium stibogluconate]]=
The wholesale price in the developing world is 9.66 USD per vial.{{cite web|title=Sodium Stibogluconate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=728&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=6 December 2016}} This gives the cost for a course of treatment at between 12 and 56 USD.{{cite book|title=Control of the leishmaniasis: report of a meeting of the WHO Expert Committee on the Control of Leishmaniases|date=March 2010|publisher=World Health Organization|isbn=9789241209496|page=55,186|url=http://apps.who.int/iris/bitstream/10665/44412/1/WHO_TRS_949_eng.pdf?ua=1|url-status=live|archive-url=https://web.archive.org/web/20160608074251/http://apps.who.int/iris/bitstream/10665/44412/1/WHO_TRS_949_eng.pdf?ua=1|archive-date=2016-06-08|df=}}
=[[Sodium zirconium cyclosilicate]]=
In the United States it costs about $US24 per dose.{{cite web |title=Lokelma Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/lokelma |website=Drugs.com |accessdate=11 October 2019 |language=en}} In the United Kingdom as of 2019 it costs the NHS about £7.12 per dose.{{cite web |title=SODIUM ZIRCONIUM CYCLOSILICATE {{!}} Medicinal forms {{!}} BNF content published by NICE |url=https://webcache.googleusercontent.com/search?q=cache:9v3PbuaPblAJ:https://bnf.nice.org.uk/medicinal-forms/sodium-zirconium-cyclosilicate.html+&cd=1&hl=en&ct=clnk&gl=ca |website=webcache.googleusercontent.com |publisher=NICE |accessdate=11 October 2019}}
=[[Solifenacin]]=
A month's supply in the United Kingdom costs the NHS about £27.62 as of 2019.BNF76, page 761 In the United States the wholesale cost of this amount is about 370 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
== Cost ==
A 2006 cost-effectiveness study found that 5 mg solifenacin had the lowest cost and highest effectiveness among anticholinergic drugs used to treat overactive bladder in the United States, with an average medical cost per successfully treated patient of $6863 per year.{{cite journal |vauthors=Ko Y, Malone DC, Armstrong EP | title = Pharmacoeconomic evaluation of antimuscarinic agents for the treatment of overactive bladder | journal = Pharmacotherapy | volume = 26 | issue = 12 | pages = 1694–702 |date=Dec 2006 | doi = 10.1592/phco.26.12.1694 |url=https://www.jstage.jst.go.jp/article/jjp/86/3/86_3_281/_pdf|PMID = 17125433}} By 2019, with the introduction of generics, the retail cost of a month's supply was down to $20 in the US.
=[[Sotalol]]=
A month supply in the United Kingdom costs the NHS about 5 £ as of 2019.BNF76, page 108 In the United States the wholesale cost of this amount is about US$11.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Spectinomycin]]=
=[[Spironolactone]]=
The wholesale cost in the developing world as of 2014 is between {{US$}}0.02 and {{US$}}0.12 per day.{{cite web|title=Spironolactone|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=731&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=29 November 2015}} In the United States it costs about {{US$}}0.50 per day.{{cite web|title=Spironolactone|url=https://www.drugs.com/monograph/spironolactone.html|publisher=The American Society of Health-System Pharmacists|accessdate=Oct 24, 2015}}
=[[Stavudine]]=
The wholesale cost in the developing world is US$1.86–5.40 per month.{{cite web|title=Stavudine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=734&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=30 November 2016}}
==Adverse events==
On Monday 30 November 2009, the World Health Organization stated that "[The WHO] recommends that countries phase out the use of Stavudine, or d4T, because of its long-term, irreversible side-effects. Stavudine is still widely used in first-line therapy in developing countries due to its low cost and widespread availability. Zidovudine (AZT) or tenofovir (TDF) are recommended as less toxic and equally effective alternatives."{{cite web |publisher=World Health Organization |url=http://www.who.int/mediacentre/news/releases/2009/world_aids_20091130/en/index.html |title=New HIV recommendations to improve health, reduce infections and save lives |date=November 30, 2009 |df= }}
=[[Streptokinase]]=
The wholesale cost is between 30.00 and US$138.00 per dose as of 2014.{{cite web|title=Streptokinase|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=968&searchYear=2014|website=International Drug Price Indicator Guide|access-date=28 November 2015|df=}}
=[[Streptomycin]]=
The wholesale cost in the developing world is between US$0.38 and $4.39 per day.{{cite web|title=Streptomycin Sulfate |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=735&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=December 8, 2016}} In the United States, a course of treatment costs more than $200.TarasconPP2015, page 36
=[[Sucralfate]]=
In the United States the wholesale cost is about US$0.22 per dose.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Sulfadiazine]]=
The wholesale cost in the developing world is about US$2.70 to 7.32 a month.{{cite web|title=Sulfadiazine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=739&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States, treatment costs more than $200 per month.TarasconPP2015, page 104
=[[Sulfadoxine/pyrimethamine]]=
The wholesale cost in the developing world is about US$0.08–0.36 per day.{{cite web|title=Sulfadoxine + Pyrimethamine |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=742&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Sulfasalazine]]=
The wholesale cost in the developing world is about US$9–33 a month as of 2014.{{cite web|title=Sulfasalazine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=745&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016|df=}} In the United States it costs $25–50 per month for a typical dose.TarasconPP2015, page 464
=Cost=
=[[Sumatriptan]]=
In the United Kingdom it costs the NHS about £1 per dose as of 2019.BNF76, page 474 In the United States the wholesale cost of this amount is about US$0.60.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Sumatriptan/naproxen sodium]]=
In the United States the combination costs about 50 USD per dose.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}} By themselves a dose of sumatriptan costs about 0.60 USD while a dose of naproxen is about 0.18 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Suxamethonium chloride]]=
The wholesale cost in the developing world is about US$0.45 to US$1.31 a dose.{{cite web|title=Suxamethonium Cl|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=747&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}}
=[[Tadalafil]]=
In the UK it costs the NHS about 0.80 £ per dose as of 2019.BNF76, page 796 In the United States the wholesale cost of this amount is about US$1.91.{{cite web |title=NADAC as of 2019-05-15 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-05-15/rt4v-78r4 |website=Centers for Medicare and Medicaid Services |accessdate=29 May 2019 |language=en}}
==Cost==
In the United States, the wholesale cost of tadalafil as of May 2019 is US$1.91 for the 20 mg tabs and US$7.65 for the 2.5 mg tabs.
While some health insurance providers cover at least part of the cost (typically limiting the number of doses covered per month), many providers, including those operating under Medicare Part D, do not cover the cost of medications prescribed for erectile dysfunction.{{cite news|last1=Parker-Pope|first1=Tara|title=The Cost of Treating Erectile Dysfunction|url=http://well.blogs.nytimes.com/2009/08/28/the-cost-of-treating-erectile-dysfunction/|accessdate=20 Dec 2016|work=New York Times|date=August 28, 2009}}{{cite news|last1=United Health Care|title=Coverage Summary -- Impotence Treatment|url=https://www.unitedhealthcareonline.com/ccmcontent/ProviderII/UHC/en-US/Assets/ProviderStaticFiles/ProviderStaticFilesPdf/Tools%20and%20Resources/Policies%20and%20Protocols/UnitedHealthcare%20Medicare%20Coverage/Impotence_Treatment_UHCMA_CS.pdf|accessdate=20 Dec 2016|publisher=United Health Care|date=August 16, 2016}}
In the U.K., a generic version of tadalafil became available in November 2017, reducing its price per pill, and will be available on the NHS. Additionally, Tadacip, manufactured in India by Cipla, is considerably less expensive.
=[[Tafenoquine]]=
In the United States, {{as of|2019|lc=yes}}, a course of treatment costs about US$43.{{cite web |title=Krintafel Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/krintafel |website=Drugs.com |accessdate=22 November 2019 }} Tafenoquine is related to primaquine.{{cite web |title=Tafenoquine Approved for Malaria Prophylaxis and Treatment |url=https://wwwnc.cdc.gov/travel/news-announcements/tafenoquine-malaria-prophylaxis-and-treatment |website=Centers for Disease Control and Prevention (CDC) |date=25 April 2019 |accessdate=22 November 2019}}
=[[Tamoxifen]]=
The wholesale price in the developing world is about US$0.07–0.23 per day.{{cite web|title=Tamoxifen Citrate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=750&searchYear=2014|website=International Drug Price Indicator Guide|access-date=28 November 2015}} In the United States, it costs about $1 per day.{{cite web|title=Tamoxifen Citrate|url=https://www.drugs.com/monograph/tamoxifen-citrate.html|work=The American Society of Health-System Pharmacists|access-date=27 Nov 2015}}
=[[Tamsulosin]]=
In the United States, the wholesale cost per dose is less than 0.10 USD as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}} In the United Kingdom, it costs the NHS 0.04 pounds per dose as of 2018.BNF76, page 767
=[[Telmisartan]]=
A month supply in the United Kingdom costs the NHS less than £2 as of 2019.BNF76, page 178 In the United States the wholesale cost of this amount is about US$10.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
==Society and culture==
A month supply in the United Kingdom costs the NHS less than £2 as of 2019. In the United States the National Average Drug Acquisition Cost of this amount is about US$10 as of 2019.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Telmisartan/amlodipine]]=
In the United States it costs at least US$57 per month as of 2019.{{cite web |title=Amlodipine/telmisartan Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/amlodipine-telmisartan#oral-tablet-5-mg-40-mg |website=Drugs.com |accessdate=30 October 2019 |language=en}}
=[[Telmisartan/hydrochlorothiazide]]=
A month of medication costs the NHS about £17 as of 2018.BNF76, page 178 In the United States it costs about US$65 per month as of 2019.{{cite web |title=Hydrochlorothiazide/telmisartan Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/hydrochlorothiazide-telmisartan |website=Drugs.com |accessdate=29 October 2019 |language=en}}
=[[Temazepam]]=
A month supply in the United Kingdom costs the NHS about £1.40 as of 2019.BNF76, page 481 In the United States, the wholesale cost of this amount is about US$1.76.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Tenofovir disoproxil]]=
The wholesale cost in the developing world is between US$3.30 and $29.13 per month.{{cite web|title=Tenofovir Disoproxil Fumerate (Tdf)|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1247&searchYear=2014|website=International Drug Price Indicator Guide|access-date=30 November 2016}} As of 2015 the cost for a typical month of medication in the United States is more than $200.TarasconPP2015, page 66
=[[Terazosin]]=
A month supply in the United Kingdom costs the NHS less than 2 £ as of 2019.BNF76, page 768 In the United States the wholesale cost of this amount is about US$4.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Terbinafine]]=
The wholesale cost in the developing world is about 2.20 USD for a 20 g tube.{{cite web | title = Terbinafine | url = http://mshpriceguide.org/en/single-drug-information/?DMFId=1562&searchYear=2014 | website = International Drug Price Indicator Guide | accessdate = 8 December 2016 }} In the United States the price in 1999 was $547 for a 12-week course; this fell to $10 by 2015, after the patent had expired.{{cite journal |vauthors=Mikailov A, Cohen J, Joyce C, Mostaghimi A | title = Cost-effectiveness of Confirmatory Testing Before Treatment of Onychomycosis | journal = JAMA Dermatology | volume = 152 | issue = 3 |year = 2015| pmid = 26716567 | doi = 10.1001/jamadermatol.2015.4190 | pages=1–6}}
=[[Tetanus vaccine]]=
The wholesale cost in the developing world is between 0.17 and 0.65 USD per dose as of 2014.{{cite web|title=Vaccine, Tetanus Toxoid|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=800&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=6 December 2015}} In the United States a course of tetanus vaccine is between 25 and 50 USD.TarasconPP2015, page 317
=[[Tetracaine]]=
The wholesale cost in the developing world is about US$1.34–1.63 per 10 ml bottle.{{cite web|title=Tetracaine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=754&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom the eye drops cost the NHS about 0.49 pounds per dose.BNF69, pages 769, 897
=[[Tetracycline]]=
The wholesale cost in the developing world is about 0.35 to 1.78 USD for a course of treatment.{{cite web|title=Tetracycline HCL|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=760&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States a course of treatment typically costs less than 25 USD.TarasconPP2015, page 107 Tetracycline was originally made from bacteria of the Streptomyces type.{{cite web|title=Tetracycline|url=https://www.drugs.com/monograph/tetracycline.html|publisher=The American Society of Health-System Pharmacists|accessdate=8 December 2016}}
==Price==
According to data from EvaluatePharma and published in the Boston Globe, the price of tetracycline rose from $0.06 per 250-mg pill in 2013 to $4.06 a pill in 2015.{{cite web | url=https://www.bostonglobe.com/business/2015/11/06/generic-drug-price-increases-alarm-insurers-providers-and-consumers/H3iA9CSxAUylnCdGjLNKVN/story.html?event=event25 | title=As competition wanes, prices for generics skyrocket | work=Boston Globe | date=6 November 2015 | accessdate=18 November 2015 | author=McCluskey, Priyanka Dayal }} The Globe described the "big price hikes of some generic drugs" as a "relatively new phenomenon" which has left most pharmacists "grappling" with large upswings" in the "costs of generics, with 'overnight' price changes sometimes exceeding 1,000%."
=[[Thalidomide]]=
In the United Kingdom it costs the NHS about £1,194 per month as of 2018.BNF76, page 936 This amount in the United States costs about US$9,236 as of 2019.{{cite web |title=Thalomid Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/thalomid |website=Drugs.com |accessdate=15 November 2019 |language=en}}
==Cost==
In the United Kingdom it costs the NHS about £1,194 per month as of 2018. This amount in the United States costs about US$9,236 as of 2019.
=[[Thiamazole]]=
A month supply in the United States has a wholesale cost of about US$6.80.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 }} It is also available in Europe and Asia.{{cite journal |last1=Jastrzębska |first1=Helena |title=Antithyroid drugs |journal=Thyroid Research |date=2015 |volume=8 |issue=Suppl 1 |pages=A12 |doi=10.1186/1756-6614-8-S1-A12|pmc=4480840 }}
=[[Thiamine]]=
The wholesale cost in the developing world (as of 2016) is about US$2.17 per one gram vial.{{cite web|title=Vitamin B1|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=956&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United States a month's supply of a multivitamin containing thiamine is less than US$25.TarasconPP2015, page 230
=[[Timolol]]=
The wholesale cost in the developing world is about US$0.86–2.29 per 5 ml bottle.{{cite web|title=Timolol Maleate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=773&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States it costs US$25–50 per month.TarasconPP2015, page 411
=[[Tioguanine]]=
The wholesale price in the developing world is about 7.07 USD per 40 mg pill as of 2014.{{cite web|title=Tioguanine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=957&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=28 November 2015}} In the United Kingdom this amount costs the NHS about 4.14 pounds.BNF69, pages 588, 592
=[[Tiotropium bromide]]=
In the United States the wholesale cost was about US$13.75 per dose as of 2019.{{cite web |title=NADAC as of 2019-01-30 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-01-30/2c5s-3kst |website=Centers for Medicare and Medicaid Services |accessdate=31 January 2019 }} In the United Kingdom a dose costs the NHS about 0.86 pounds as of 2019.BNF76, pages 247–248
=[[Tizanidine]]=
A month supply in the United Kingdom costs the NHS about 3.45 £ as of 2019.BNF76, page 1094 In the United States the wholesale cost of this amount is about US$4.20.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 |language=en}}
=[[Tolterodine]]=
A month supply costs the NHS about GB£2.09 per month as of 2019.BNF76, page 762 In the United States the wholesale cost of this amount is about US$37.16.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Topiramate]]=
A month supply in the United Kingdom costs the NHS about £1.40 per month as of 2019.BNF76, page 328 In the United States the wholesale cost of this amount is about 4.00 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Torasemide]]=
A month supply in the United Kingdom costs the NHS less than 10 £ as of 2019.BNF76, pages 227–228 In the United States the wholesale cost of this amount is about XXX USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Tramadol]]=
In the United States, the wholesale cost is less than US$0.05 per dose as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}}
=[[Tranexamic acid]]=
The wholesale cost in the developing world is about 4.38 to US$4.89 for a course of treatment.{{cite web|title=Tranexamic Acid|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1470&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United States, a course of treatment costs between 100 and US$200.TarasconPP2015
=[[Trastuzumab]]=
{{As of|2014}}, the wholesale price in the developing world is between {{US$}}1,800 and {{US$}}1,955 per 440 mg vial.{{cite web|title=Trastuzumab|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1471&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=28 November 2015}} In the United Kingdom, a 150 mg vial costs the NHS £407.00.BNF69, page 626
==Costs==
Trastuzumab costs about {{US$|70,000}} for a full course of treatment,{{cite journal | author = Fleck L | title = The costs of caring: Who pays? Who profits? Who panders? | journal = Hastings Cent Rep | volume = 36 | issue = 3 | pages = 13–7 | year = 2006| pmid = 16776017 | doi = 10.1353/hcr.2006.0040}} Trastuzumab brought in $327 million in revenue for Genentech in the fourth quarter of 2007.{{cn|date=December 2019}}
Australia has negotiated a lower price of A$50,000 per course of treatment.{{cite web | publisher = Australian Government, Dept of Health and Ageing | title = Listing of Herceptin on PBS | date = 2006-10-01 | url = http://www.health.gov.au/internet/main/publishing.nsf/Content/herceptin-govtdecision.htm | access-date = 2009-08-06 }}
Since October 2006, trastuzumab has been made available for Australian women and men with early-stage breast cancer via the Pharmaceutical Benefits Scheme. This is estimated to cost the country over A$470 million for 4–5 years supply of the drug.Australian Government, Dept of Health and Ageing "Listing of Herceptin on PBS", 2006-10-1. {{cite web |url=http://www.pbs.gov.au/info/news/2006/10/listing-of-herceptin |title=Pharmaceutical Benefits Scheme (PBS) | Listing of Herceptin on the PBS |accessdate=2013-10-20 }}
Roche has changed the trade name of the drug and has re-introduced an affordable version of the same in the Indian market.{{when|date=December 2019}} The new drug named Herclon would cost approximately RS75,000 INR ({{US$}}1,200) {{clarify|reason=Per month?|date=August 2017}} in the Indian market.{{citation needed|date=June 2013}}
On September 16, 2014, Genentech notified hospitals in the United States that, as of October, trastuzumab could only be purchased through their selected specialty drugs distributors not through the usual general line wholesalers. By being forced to purchase through specialty pharmacies, hospitals lost rebates from the big wholesalers and the ability to negotiate cost-minus discounts with their wholesalers.{{cite web | url=http://time.com/3541484/cancer-drug-price-hikes/ | title=Hospitals Furious at Cancer-Drug Price Hikes | website=Time | date=27 October 2014 | accessdate=26 October 2015 | author=Saporito, Bill }}
=[[Travoprost]]=
A 2.5 milliliter bottle in the United Kingdom costs the NHS about 7.30 £ as of 2019.BNF76, page 1152 In the United States the wholesale cost of this amount is about US$177.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Trazodone]]=
The cost in the United Kingdom for the NHS is about £7.46 per month as of 2019.BNF76, page 367 In the United States, the wholesale cost is about {{US$}}4.53 per month as of 2018.{{cite web|title=NADAC as of 2018-01-03 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-01-03/v54n-gpyk |publisher=Centers for Medicare and Medicaid Services|accessdate=7 January 2018|language=en}}
=[[Triamcinolone]]=
In the United States the wholesale cost is about US$0.06 per gram for the cream.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |access-date=3 March 2019 |language=en}}
=[[Tropicamide]]=
The wholesale cost in the developing world is about US$4.19–4.55 per 15 ml bottle.{{cite web|title=Tropicamide|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=786&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United States a course of treatment costs less than $25.TarasconPP2015, page 415
=[[Tuberculin]]=
The wholesale cost in the developing world is about 0.22 USD per dose.{{cite web|title=Tuberculin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=953&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United States testing costs less than 25 USD.TarasconPP2015, page 323
=[[Typhoid vaccine]]=
The wholesale cost in the developing world is about US$4.44 per dose as of 2014.{{cite web|title=Vaccine, Typhoid|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=801&searchYear=2014|website=International Drug Price Indicator Guide|access-date=6 December 2015}} In the United States they cost $25–50.TarasconPP2015, page 317
=[[Valaciclovir]]=
A month supply in the United Kingdom costs the NHS about £3 as of 2019.BNF76, pages 625–626 In the United States the wholesale cost of this amount is about US$2.80.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 }} In 2016 it was the 168th most prescribed medication in the United States with more than 3 million prescriptions.{{cite web |title=The Top 300 of 2019 |url=https://clincalc.com/DrugStats/Top300Drugs.aspx |website=clincalc.com |accessdate=22 December 2018}}
==History==
A month supply in the United Kingdom costs the NHS about £3 as of 2019. In the United States the wholesale cost of this amount is about US$2.80.
=[[Valganciclovir]]=
The wholesale price in the developing world is between 30.16 and 52.14 USD per day.{{cite web|title=Valganciclovir|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1395&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=29 November 2016}} In the United States as of 2016 the wholesale costs were about 58.54 USD per day.{{cite web|title=NADAC|url=https://data.medicaid.gov/Drug-Prices/NADAC-as-of-2016-11-30/rfpb-hznz|website=Medicaid.gov|accessdate=29 November 2016}}
==Price and patent status==
The price of a four-month course of valganciclovir from Roche is about US$8,500 in high-income countries, $6,000 in India. However, the valganciclovir patent was rejected by the Indian Patent Office[https://web.archive.org/web/20120303202514/http://www.msf.org.uk/victory_for_access_to_medicine_20100506.news Valganciclovir rejected by the Indian Patent Office]
=[[Valproate]]=
The wholesale cost in the developing world is about {{US$|link=yes}}0.40 per day as of 2015.{{cite web |title=Sodium Valproate {{!}} International Medical Products Price Guide |url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1390&searchYear=2015}} In the United States, the wholesale cost is roughly {{US$}}1.30 per day as of 2019.{{cite web |title=NADAC as of 2019-11-27 {{!}} Data.Medicaid.gov |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-11-27/qjsh-shte |website=Centers for Medicare and Medicaid Services |accessdate=25 November 2019 |language=en}}
==Cost==
The wholesale cost in the developing world is about {{US$|link=yes}}0.40 per defined daily dose as of 2015. In the United States, the National Average Drug Acquisition Cost is roughly {{US$}}1.30 per day for the short acting formulation as of 2019. The price to a consumer in the United States for this amount is about $US2.30 per day as of 2019.{{cite web |title=Valproic acid Prices, Coupons & Patient Assistance Programs |url=https://www.drugs.com/price-guide/valproic-acid |website=Drugs.com |accessdate=25 November 2019 |language=en}} The long acting formulations are more expensive. In the European Union, end-user costs are less than 0.60 EUR for an average daily dose in Germany.Regular pharmacy price, including all taxes, et cetera: less than 34,43 EUR for 200 controlled release pills with 500mg each; date: 2016-11-30{{citation needed|date=November 2016}}
=[[Valsartan]]=
A month supply in the United Kingdom costs the NHS about 5 £ per month as of 2019.BNF76, page 179 In the United States the wholesale cost of this amount is about US$7.50.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019}}
=[[Valsartan/hydrochlorothiazide]]=
A month supply in the United Kingdom costs the NHS about 1.85 as of 2019.BNF76, page 179 In the United States the wholesale cost of this amount is about US$4.40.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Vancomycin]]=
The wholesale cost in the developing world of an intravenous dose is about US$1.70 to 6.00.{{cite web|title=Vancomycin|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=954&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=5 September 2015}} In the United States, the capsules are more expensive than the intravenous solution.{{cite web|title=Vancocin|url=https://www.drugs.com/monograph/vancocin.html|publisher=The American Society of Health-System Pharmacists|accessdate=Sep 4, 2015}}
=Cost=
The wholesale cost of an intravenous dose is about US$1.70 to 6.00. In the United States, the wholesale cost of the pills are about US$300 for a course of treatment as of 2018.{{cite web|title=NADAC as of 2018-01-17|url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-01-17/vd4a-ygn2|website=Centers for Medicare and Medicaid Services|accessdate=20 January 2018|language=en}}
=[[Venlafaxine]]=
In the United States the wholesale cost per dose is less than {{USD|0.20}} as of 2018.{{cite web |title=NADAC as of 2018-12-19 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2018-12-19/g7bs-ahj4 |website=Centers for Medicare and Medicaid Services |accessdate=22 December 2018 |language=en}}
=[[Verapamil]]=
The wholesale cost in the developing world is about US$1.71–2.70 per month.{{cite web|title=Verapamil HCL|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=806&searchYear=2014|website=International Drug Price Indicator Guide|access-date=8 December 2016}} In the United States a month of treatment costs $25–50.TarasconPP2015, page 156 Long acting formulations exist.{{cite book|title=WHO Model Formulary 2008|date=2009|publisher=World Health Organization|isbn=9789241547659|page=267|url=http://apps.who.int/medicinedocs/documents/s16879e/s16879e.pdf|access-date=8 December 2016|df=dmy-all}}
=[[Vilazodone]]=
In the United States the wholesale cost for a month of medication is about 261 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Vinblastine]]=
As of 2014 the wholesale cost in the developing world is about {{US$}}7.70 and {{US$}}31.70 per dose.{{cite web|title=Vinblastine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=809&searchYear=2014|accessdate=28 November 2015}} In the United Kingdom it costs £13.09 per 10 mg vial.BNF69, page 593
=[[Vincristine]]=
The wholesale cost in the developing world is between US$1.80 and US$42.60 per dose.{{cite web|title=Vincristine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=810&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=28 November 2015}}
=[[Vinorelbine]]=
The wholesale price in the developing world as of 2014 is between 18.10 and 42.82 USD per 50 mg vial.{{cite web|title=Vinorelbine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1668&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=28 November 2015}} This amount in the United Kingdom costs the NHS about 139.00 pounds.BNF69, page 594
=[[Vitamin C]]=
==Industrial production==
In 2017, China produced about 95% of the world supply of ascorbic acid (vitamin C),{{cite web |author1=Jeff Gelski |title=Vitamin C prices triple in a year's time |url=https://www.foodbusinessnews.net/articles/10836-vitamin-c-prices-triple-in-a-year-s-time |publisher=FoodBusiness News |accessdate=15 August 2019 |date=6 November 2017}} which is China's most exported vitamin, having total revenue of US$880 million in 2017.{{cite web |author1=Tingmin Koe |title='China-free' vitamin C: Industry defends standards against 'marketing claims' |url=https://www.nutraingredients-asia.com/Article/2018/08/27/China-free-vitamin-C-Industry-defends-standards-against-marketing-claims# |publisher=NutraIngredients-Asia.com, William Reed Business Media, Ltd |accessdate=15 August 2019 |date=28 August 2018}} Due to pressure on Chinese industry to discontinue burning coal normally used for vitamin C manufacturing, the price of vitamin C rose three-fold in 2016 alone to US$12 per kg.
=[[Voriconazole]]=
The wholesale cost in the United States, as of 2019, is about 9 USD per day.{{cite web|title=NADAC as of 2019-08-21|url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-08-21/8h2n-xgjm|website=Centers for Medicare and Medicaid Services|accessdate=2019-09-23|language=en}}
=[[Vortioxetine]]=
A month supply in the United Kingdom costs the NHS about £27.72 as of 2019.BNF76, page 376 In the United States the wholesale cost of this amount is about 368.40 USD.{{cite web |title=NADAC as of 2019-02-27 |url=https://data.medicaid.gov/Drug-Pricing-and-Payment/NADAC-as-of-2019-02-27/s7c9-pfa6 |website=Centers for Medicare and Medicaid Services |accessdate=3 March 2019 |language=en}}
=[[Warfarin]]=
The wholesale cost in the developing world is about US$1.12 to 7.20 for a typical month of treatment.{{cite web |title = Warfarin Sodium |url = http://mshpriceguide.org/en/single-drug-information/?DMFId=846&searchYear=2014 |website = International Drug Price Indicator Guide |accessdate = 8 December 2016 |df = dmy-all }} In the United States it usually costs less than $25 a month.TarasconPP2015, page 289
=[[Water for injection]]=
The wholesale cost in the developing world is about US$0.03–0.15 per 10 ml vial.{{cite web|title=Water for Injection|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=852&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom this amount cost the NHS 0.25 to 1.40 pounds.BNF69, page 685
=[[Xylometazoline]]=
The wholesale cost in the developing world is about 0.75 USD for a 10 ml bottle.{{cite web|title=Xylometazoline|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1630&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom that dose costs the NHS about 2.10 pounds.BNF69, page 786
=[[Yellow fever vaccine]]=
The wholesale price in the developing world is between US$4.30 and US$21.30 per dose as of 2014.{{cite web|title=Vaccine, Yellow Fever|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=802&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=6 December 2015}} In the United States it costs between US$50 and US$100.TarasconPP2015, page 318
=[[Zidovudine]]=
The wholesale cost in the developing world is US$5.10 to $25.60 per month.{{cite web|title=Zidovudine|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=985&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=November 28, 2016}} {{As of|2015}}, the cost for a typical month of medication in the United States was more than $200.TarasconPP2015, page 67
=[[Zinc sulfate (medical use)]]=
The wholesale cost in the developing world is about US$0.01–18 per day.{{cite web|title=Zinc Sulfate|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1191&searchYear=2014|website=International Drug Price Indicator Guide|accessdate=8 December 2016}} In the United Kingdom ten days of treatment costs the NHS about 4.32 pounds.BNF69, page 700
=[[Zoledronic acid]]=
The wholesale cost in the developing world is between 5.73 USD and 26.80 USD per vial.{{cite web|title=Single Drug Information|url=http://mshpriceguide.org/en/single-drug-information/?DMFId=1669&searchYear=2015|website=International Medical Products Price Guide|accessdate=9 December 2017}} In the United Kingdom, as of 2015, a dose costs the NHS about 220 pounds.BNF69, page 528
References
{{Reflist}}
- {{cite book|title=British National Formulary : BNF 69|date=2015|publisher=British Medical Association|isbn=9780857111562|edition=69}}
- {{cite book|title=British national formulary : BNF 74|date=2017|publisher=British Medical Association|isbn=978-0857112989|edition=74}}
- {{cite book|title=British national formulary : BNF 76|date=2018|publisher=Pharmaceutical Press|isbn=9780857113382|edition=76}}
- {{cite book|last1=Hamilton|first1=Richard J.|title=Tarascon Pharmacopoeia|date=2011|publisher=Jones & Bartlett Learning|location=Sudbury, MA|isbn=9781449600679|edition=2011 library ed., 2011 ed., 12th}}
- {{cite book|last1=Hamilton|first1=Richard J.|title=Tarascon Pocket Pharmacopoeia : delux lab-coat edition|date=2013|publisher=Jones & Bartlett Learning|location=Sudbury,MA|isbn=9781449673611|edition=14}}
- {{cite book|last1=Hamilton|first1=Richard J.|title=Tarascon Pocket Pharmacopoeia : 2014 deluxe lab-pocket edition|date=2014|location=Sudbury, MA|publisher=Jones & Bartlett Learning|isbn=9781284053999|edition=15}}
- {{cite book|last1=Hamilton|first1=Richard J.|title=Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition|date=2015|location=Sudbury, MA|publisher=Jones & Bartlett Learning|isbn=9781284057560}}
- {{cite book|last1=Hamilton|first1=Richard J.|title=Tarascon Pharmacopoeia 2016 Professional Desk Reference Edition|date=2016|location=Sudbury, MA|publisher=Jones & Bartlett Publishers|isbn=9781284095302|edition=6}}
- {{cite book|last1=Hamilton|first1=Richard J.|title=Tarascon Pocket Pharmacopoeia 2019 Deluxe Lab-Coat Edition |date=2018 |location=Sudbury, MA|publisher=Jones & Bartlett Learning |isbn=978-1-284-16754-2|edition=20}}