VAMP5

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{infobox protein

|Name=vesicle-associated membrane protein 5 (myobrevin)

|caption=

|image=

|width=

|HGNCid=12646

|Symbol=VAMP5

|AltSymbols=

|EntrezGene=10791

|OMIM=607029

|RefSeq=NM_006634

|UniProt= O95183

|PDB=

|ECnumber=

|Chromosome=2

|Arm=p

|Band=11.2

|LocusSupplementaryData=

}}

Vesicle-associated membrane protein 5 (VAMP-5) is a synaptobrevin protein encoded in the human by the VAMP5 gene.{{cite journal | vauthors = Zeng Q, Subramaniam VN, Wong SH, Tang BL, Parton RG, Rea S, James DE, Hong W | title = A novel synaptobrevin/VAMP homologous protein (VAMP5) is increased during in vitro myogenesis and present in the plasma membrane | journal = Molecular Biology of the Cell | volume = 9 | issue = 9 | pages = 2423–37 |date=September 1998 | pmid = 9725904 | pmc = 25509 | doi = 10.1091/mbc.9.9.2423| url = http://www.molbiolcell.org/cgi/content/abstract/9/9/2423 }}{{cite web | title = Entrez Gene: STX12 syntaxin 12| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10791 }}

Function

VAMPs (synaptobrevins) along with syntaxins and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of vesicles and cell membranes. The VAMP5 gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. This VAMP family member may participate in vesicle trafficking events that are associated with myogenesis.

References

External links

{{MeshName|VAMP5+protein,+human|3=VAMP5 protein, human}}