VFDB

{{Short description|Biological database}}

{{Infobox biodatabase|title=Virulence Factor Database|logo=|description=A database that tracks bacterial virulence factors|scope=Pathogenic bacteria|organism=Bacteria|center=|laboratory=|author=|pmid=15608208|released=|standard=|format=|url={{URL|http://www.mgc.ac.cn/VFs/main.htm}}|download=|webservice=|sql=|sparql=|webapp=|standalone=|license=|versioning=|frequency=|curation=|bookmark=yes|version=}}VFDB also known as Virulence Factor Database is a database that provides scientist quick access to virulence factors in bacterial pathogens.{{cite journal|last=Chen|first=L.|date=2004-12-17|title=VFDB: a reference database for bacterial virulence factors|journal=Nucleic Acids Research|language=en|volume=33|issue=Database issue|pages=D325–D328|doi=10.1093/nar/gki008|pmid=15608208|issn=1362-4962|pmc=539962}} It can be navigated and browsed using genus or words. A BLAST tool is provided for search against known virulence factors.{{cite journal|last=Altschul|first=S.|date=1997-09-01|title=Gapped BLAST and PSI-BLAST: a new generation of protein database search programs|journal=Nucleic Acids Research|volume=25|issue=17|pages=3389–3402|doi=10.1093/nar/25.17.3389|pmid=9254694|issn=1362-4962|pmc=146917}} VFDB contains a collection of 16 important bacterial pathogens. Perl scripts were used to extract positions and sequences of VF from GenBank.{{cite journal|last1=Benson|first1=D. A.|last2=Karsch-Mizrachi|first2=I.|last3=Lipman|first3=D. J.|last4=Ostell|first4=J.|last5=Sayers|first5=E. W.|date=2009-01-01|title=GenBank|journal=Nucleic Acids Research|volume=37|issue=Database|pages=D26–D31|doi=10.1093/nar/gkn723|pmid=18940867|pmc=2686462|issn=0305-1048}} Clusters of Orthologous Groups (COG) was used to update incomplete annotations. More information was obtained by NCBI. VFDB was built on Windows operation systems on DELL PowerEdge 1600SC servers.{{cn|date=June 2022}}