Vector NTI

{{Short description|Software package}}

{{Infobox software

| name = Vector NTI

| logo =

| screenshot =

| caption =

| developer = Life Technologies

| latest_release_version = Vector NTI Express v1.1.1 (Mac & Windows); Vector NTI Advance v11.5.2 (Windows & Mac w/PC Emulation)

| latest_release_date = {{start date|2012|09|20}}

| operating_system = Mac OS X 10.6+, Microsoft Windows XP, Windows 7

| genre = Molecular biology Suite of Sequence Analysis & Design Software Tools (Curate, Discover, Design, Provision, Confirm)

| license = Proprietary

| website = [http://www.lifetechnologies.com/es/en/home/life-science/cloning/vector-nti-software.html Vector NTI home]

}}

Vector NTI was a commercial bioinformatics software package used by many life scientists in the early 2000s to work, among other things, with nucleic acids and proteins in silico.{{Cite web|url=http://www.basic.northwestern.edu/VectorNTI/Documentation/VectorNTI/Introduction.htm|title=Home}}{{cite web|url=http://biodoc.ist.unomaha.edu/wiki/Vector_NTI|archive-url=https://web.archive.org/web/20141208082033/http://biodoc.ist.unomaha.edu/wiki/Vector_NTI|title=Vector NTI|archive-date=2014-12-08|access-date=2023-08-11}} It allowed researchers to, for example, plan a DNA cloning experiment on the computer before actually performing it in the lab.

It was originally created by InforMax Inc, North Bethesda, MD in 1993 and versions in the early 2000s were well reviewed at the time.{{Cite journal |last=Tippmann |first=H.-F. |date=2004-01-01 |title=Analysis for free: Comparing programs for sequence analysis |journal=Briefings in Bioinformatics |volume=5 |issue=1 |pages=82–87 |doi=10.1093/bib/5.1.82 |pmid=15153308 |issn=1467-5463|doi-access=free }}{{Cite journal |last=Lu |first=G. |date=2004-01-01 |title=Vector NTI, a balanced all-in-one sequence analysis suite |journal=Briefings in Bioinformatics |language=en |volume=5 |issue=4 |pages=378–388 |doi=10.1093/bib/5.4.378 |pmid=15606974 |issn=1467-5463|doi-access=free }} However, in 2008 it was locked and turned into a commercial software after 2008 which created problems for locked in users who were forced to buy the software to continue accessing their data on newer computers.{{Cite web|url=http://www.protocol-online.org/biology-forums/posts/41708.html|title = Vector NTI no longer free - Molecular Cloning}} What was previously a single software package was subsequently split into Vector NTI Express, Advanced, and Express Designer.{{Cite web|url=http://www.lifetechnologies.com/de/de/home/life-science/cloning/vector-nti-software.html|title = Vector NTI Software - US}}

Vector NTI was discontinued by its corporate parent Thermo Fisher at the end of 2019 and support ceased a year later.{{cite web|url=https://www.thermofisher.com/content/dam/LifeTech/global/life-sciences/Cloning/Images/TFS_Vector-NTI-Software_FAQ.pdf|title=FREQUENTLY ASKED QUESTIONS FOR VECTOR NTI SOFTWARE|access-date=2023-08-11}}

Features

  • create, annotate, analyse, and share DNA/protein sequences{{cite journal|last1=Lu|first1=Guoqing|last2=Moriyama|first2=Etsuko|title=Vector NTI, a balanced all-in-one sequence analysis suite|journal=Briefings in Bioinformatics|date=2004|volume=5|issue=4|pages=378–388|url=http://bib.oxfordjournals.org/content/5/4/378.short|doi=10.1093/bib/5.4.378|doi-access=free|pmid=15606974}}
  • perform and save BLAST searches
  • design primers for PCR, cloning, sequencing or hybridisation experiments
  • plan cloning and run gels in silico
  • align multiple protein or DNA sequences
  • search NCBI's Entrez, view, and save DNAs, proteins, and citations
  • edit chromatogram data, assemble into contigs

See also

References

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