Warkany syndrome 1

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Warkany syndrome 1 was an X-chromosome linked recessive genetic condition originally described by Joseph Warkany in 1961 as part of an article on intrauterine growth retardation{{cite journal |author=Warkany J |title=Intrauterine growth retardation. |journal=Am. J. Dis. Child. |volume=102 |pages=249–79 |year=1961 |issue=2 |doi=10.1001/archpedi.1961.02080010251018 |pmid=13783175}} - the condition is no longer diagnosed. The family history was consistent with X-linked recessive inheritance of intrauterine growth retardation and small head size, but these features are not unique to this condition and no linkage to a specific gene was ever established. In fact, the condition appears to have been abandoned, given that the OMIM number ([https://www.ncbi.nlm.nih.gov/omim?term=308400 308400]) assigned to it ([https://www.nlm.nih.gov/archive/20061212/mesh/jablonski/cgi/jablonski/syndrome_cgi96c9.html?term=Warkany+syndrome+1&field=name]) and listed in a review article on X-linked mental retardation{{cite journal |author=Lubs H |title=XLMR genes: update 1998. |journal=Am. J. Med. Genet. |volume=83 |pages=237–47 |year=1999 |issue=4 |pmid=10208155|doi=10.1002/(SICI)1096-8628(19990402)83:4<237::AID-AJMG2>3.0.CO;2-8}} has been removed from the OMIM database. Furthermore, this condition is no longer mentioned in a more recent review of X-linked mental retardation.{{cite journal |author=Chiurazzi P |title=XLMR genes: update 2007. |journal=Eur. J. Hum. Genet. |volume=16 |pages=422–34 |year=2008 |issue=4 |pmid=18197188 |doi=10.1038/sj.ejhg.5201994|doi-access=free }}