Wim Crusio
{{Short description|Dutch behavioral neurogeneticist}}
{{Use dmy dates|date=April 2022}}
{{Infobox scientist
| name = Wim E. Crusio
| image = WimCrusio.jpg
| caption = Wim Crusio, August 2006
| birth_date = {{Birth date and age|df=yes|1954|12|20}}
| birth_place = Bergen op Zoom, The Netherlands
| native_name = Wilhelmus Elisabeth Crusio
| death_date =
| death_place =
| citizenship = Dutch
| nationality =
| ethnicity =
| fields = behavioral and neural genetics, behavioral neuroscience
| workplaces = Radboud University Nijmegen, University of Heidelberg, French National Centre for Scientific Research (CNRS; Paris, Orleans, and Talence (Bordeaux)), University of Massachusetts Medical School
| alma_mater = Radboud University Nijmegen
| thesis_title = Olfaction and behavioral responses to novelty in mice: a quantitative-genetic analysis
| thesis_url = http://repository.ubn.ru.nl/bitstream/handle/2066/148360/mmubn000001_027651975.pdf?sequence=1
| thesis_year = 1984
| doctoral_advisor = Hans van Abeelen
| academic_advisors = Bram van Overbeeke,
Hendrik de Wit,
Victor Westhoff
| doctoral_students =
| notable_students =
| known_for = Behavioral neurogenetics of the hippocampus, mouse models of neuropsychiatric disorders
| author_abbrev_bot = Crusio
| influences =
| influenced =
| awards = IBANGS Distinguished Service Award
| website = {{URL|https://wimcrusio.com/}}
}}
{{wikispecies|Wim Crusio}}
Wim E. Crusio (born Wilhelmus Elisabeth Crusio on 20 December 1954) is a Dutch behavioral neurogeneticist and a directeur de recherche (research director) with the French National Centre for Scientific Research in Talence, France.
Education and career
Crusio received his bachelor's degree in biology from Radboud University Nijmegen in 1975, where he went on to obtain a master's degree and then a PhD in 1979 and 1984, respectively.{{Cite web |url=http://www.mousebehavior.com/CV-WEC.pdf |title=Wim E. Crusio Curriculum Vitae |website=Wim E. Crusio Blog |date=February 2016 |archive-url=https://web.archive.org/web/20171107005135/http://www.mousebehavior.com/CV-WEC.pdf |archive-date=7 November 2017 |access-date=15 August 2018}} His Anubias revision, which was originally published in 1979, was translated in German{{cite journal |last1=Brünner |first1=Gerhard |title=Crusio, Wim: Die Gattung Anubias (Araceae) |journal=Aquarien Magazin |date=1987 |volume=21 |issue=7 |department=Für Ihre Bücherei |language=de}} and continues to engender interest.{{cite journal |title=Protokoll der Mitgliederversammlung 2009 des Arbeitskreises Wasserpflanzen in Dresden |journal=Aqua Planta |year=2009 |first=Wolf-Dieter |last=Klix |volume=34 |issue=4 |pages=150–151 |url=http://www.arbeitskreis-wasserpflanzen.de/aquaplanta.php |access-date=2010-08-22 |quote=Announcement of re-issue on CD of 1987 German edition of Anubias revision |language=de |archive-date=7 October 2010 |archive-url=https://web.archive.org/web/20101007080739/http://arbeitskreis-wasserpflanzen.de/aquaplanta.php |url-status=dead }} For his PhD thesis, Crusio studied the inheritance of the effects of anosmia on exploratory behavior of mice, and more in general the genetic architecture of exploratory behavior, using quantitative-genetic methods such as the diallel cross.{{cite book |url=http://repository.ubn.ru.nl/handle/2066/148360 |title=Olfaction and behavioral responses to novelty in mice: A quantitative-genetic analysis |publisher=Krips Repro |year=1984 |location=Meppel |pages=viii+146+78 |author=Crusio, WE |access-date=31 July 2016 |archive-date=14 August 2016 |archive-url=https://web.archive.org/web/20160814090047/http://repository.ubn.ru.nl/handle/2066/148360 |url-status=live }} From 1984 to 1987, Crusio worked as a postdoc at the University of Heidelberg, supported by a NATO Science Fellowship{{Cite web |url=http://www.mousebehavior.com/vitae_wec.htm |title=Curriculum Vitae Wim E. Crusio |archive-url=https://web.archive.org/web/20170130230232/http://mousebehavior.com/vitae_wec.htm |archive-date=30 January 2017 |access-date=15 August 2018}} and an Alexander von Humboldt Research Fellowship.{{cite web |url=http://www.avh.de/automat_db/pub_humboldtiana2.humboldtiana_index_pub?p_year=2005&p_group=1&p_fg2=2G |title=Publications by Humboldt Research Fellows from abroad in 2005: Biosciences, Life Sciences |access-date=2009-08-11 |archive-date=27 September 2011 |archive-url=https://web.archive.org/web/20110927223351/http://www.avh.de/automat_db/pub_humboldtiana2.humboldtiana_index_pub?p_year=2005&p_group=1&p_fg2=2G |url-status=dead }} During 1988, Crusio spent a year in Paris, France, supported by a fellowship from the Fyssen Foundation.{{cite journal |title=Liste des boursiers 1987/1988 |journal=Annales de la Fondation Fyssen |year=1989 |volume=4 }} He then returned to Heidelberg as a senior research scientist before being recruited as chargé de recherche by the CNRS, initially working in an institute of the Université René Descartes (Paris V) and later moving to the CNRS campus in Orléans, having been promoted to directeur de recherche. In 2000 he became full professor of psychiatry at the University of Massachusetts Medical School in Worcester, Massachusetts, returning to the CNRS in 2005 as a group leader in the Centre de Neurosciences Intégratives et Cognitives in Talence, a suburb of Bordeaux.{{cite web |url=http://www.cnic.u-bordeaux1.fr/rubrique.php3?id_rubrique=29 |url-status=dead |archive-url=https://web.archive.org/web/20071030031635/http://www.cnic.u-bordeaux1.fr/rubrique.php3?id_rubrique=29 |archive-date=2007-10-30 |title=CNIC UMR5228 – Equipe 3 – Neurogénétique comportementale |language=fr |access-date=2009-08-15}}{{cite web |url=http://www.inb.u-bordeaux2.fr/siteneuro2/pages/archiindex/Crusio/CrusioWim.php |title=Nouvel arrivant à l'INB, aujourd'hui : Wim CRUSIO |author=Deris, Yves |publisher=Institut des Neurosciences de Bordeaux |access-date=2009-08-23 |language=fr |archive-date=17 July 2009 |archive-url=https://web.archive.org/web/20090717061310/http://www.inb.u-bordeaux2.fr/siteneuro2/pages/archiindex/Crusio/CrusioWim.php |url-status=dead }} He is currently adjunct director of the Institut de Neurosciences Cognitives et Intégratives d'Aquitaine.{{cite web |url=http://www.incia.u-bordeaux1.fr/spip.php?article168 |title=Crusio Wim |publisher=The Aquitaine Institute for Cognitive and Integrative Neuroscience |access-date=2012-12-29 |archive-date=21 October 2014 |archive-url=https://web.archive.org/web/20141021164838/http://www.incia.u-bordeaux1.fr/spip.php?article168 |url-status=live }}
Research
= Hippocampal mossy fibers =
Crusio and his collaborators found that neuroanatomical variations in the mouse hippocampus, in particular the sizes of their intra- and infrapyramidal mossy fibers (IIPMF) correlated with learning performance.{{cite book |title=La Biologie de la Mémoire |publisher=Presses Universitaires de France |series=Que sais-je? |last1=Chapouthier |first1=Georges |author-link=Georges Chapouthier |year=1994 |pages=128 |language=fr |isbn=2-13-046261-8}} Together with Herbert Schwegler and Hans-Peter Lipp, Crusio showed that an inverse correlation, that is, animals with larger IIPMF learn better, could be found for spatial learning in a radial arm maze task.{{cite journal |title=Radial-maze performance and structural variation of the hippocampus in mice: a correlation with mossy fibre distribution |journal=Brain Research |volume=425 |issue=1 |pages=182–185 |date=November 1987 |pmid=3427419 |doi= 10.1016/0006-8993(87)90498-7|last1=Crusio |first1=W. E. |last2=Schwegler |first2=H |last3=Lipp |first3=H. P. |s2cid=39198617 }}{{cite journal |title=Hippocampal mossy fibers and radial-maze learning in the mouse: a correlation with spatial working memory but not with non-spatial reference memory |journal=Neuroscience |volume=34 |issue=2 |pages=293–298 |year=1990 |pmid=2333144 |doi= 10.1016/0306-4522(90)90139-U|last1=Schwegler |first1=H |last2=Crusio |first2=W. E. |last3=Brust |first3=I |s2cid=9557091 }}{{cite book | url=https://books.google.com/books?id=CTES09IWtm0C&pg=PA138 | title=What's Wrong with My Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice | publisher=John Wiley & Sons | author=Crawley, Jacqueline | year=2007 | pages=138 | author-link=Jacqueline Crawley | isbn=9780470119044 | access-date=8 February 2015 | archive-date=10 May 2016 | archive-url=https://web.archive.org/web/20160510175836/https://books.google.com/books?id=CTES09IWtm0C&pg=PA138 | url-status=live }} Taken together, Crusio and collaborators think that it is highly likely that this correlation is causal,{{cite journal|title=Learning spatial orientation tasks in the radial-maze and structural variation in the hippocampus in inbred mice |journal=Behavioral and Brain Functions |volume=1 |issue=3 |pages=3 |date=April 2005 |pmid=15916698 |doi=10.1186/1744-9081-1-3 |pmc=1143776|last1=Crusio |first1=W. E. |last2=Schwegler |first2=H |doi-access=free }} although this is not universally accepted.{{cite book |editor1-first=P. |editor1-last=Andersen |editor1-link=Per Andersen |editor2-first=R. |editor2-last=Morris |editor2-link=Richard G. Morris |editor3-first=D. |editor3-last=Amaral |editor3-link=David Amaral |editor4-first=T. |editor4-last=Bliss |editor4-link=Tim Bliss |editor5-last=O'Keefe |editor5-first=J. | title=The Hippocampus Book |chapter=Theories of hippocampal function | publisher=Oxford University Press |location=Oxford, UK| year=2007 |isbn=978-0-19-510027-3 |pages=581–713 |editor5-link=John O'Keefe (neuroscientist) |last=Morris | first=R.}}
= Mouse model of depression =
When mice are exposed to unpredictable chronic mild stress (UCMS), they start exhibiting symptoms reminiscent of major depressive disorder in humans.{{cite journal |author=Willner P |title=Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation |journal=Psychopharmacology |volume=134 |issue=4 |pages=319–329 |date=December 1997 |pmid=9452163 |doi=10.1007/s002130050456 |s2cid=40941720 |url=http://link.springer.de/link/service/journals/00213/bibs/7134004/71340319.htm |access-date=2009-08-15 |archive-date=30 April 1999 |archive-url=https://web.archive.org/web/19990430040840/http://link.springer.de/link/service/journals/00213/bibs/7134004/71340319.htm |url-status=live }} As it had been suggested that deficits in hippocampal neurogenesis might underlie depression,{{cite journal |title=Depressed new neurons--adult hippocampal neurogenesis and a cellular plasticity hypothesis of major depression |journal=Biological Psychiatry |volume=54 |issue=5 |pages=499–503 |date=September 2003 |pmid=12946878 |doi= 10.1016/S0006-3223(03)00319-6|last1=Kempermann |first1=G |last2=Kronenberg |first2=G |s2cid=26823096 }} Crusio and collaborators undertook a series of experiments investigating changes in behavior and neurogenesis in mice that had undergone UCMS. They showed dramatic changes in levels of aggression,{{cite journal |title=Agonistic behavior and unpredictable chronic mild stress in mice |journal=Behavior Genetics |volume=33 |issue=5 |pages=513–519 |date=September 2003 |pmid=14574128 |doi=10.1023/A:1025770616068 |url=http://www.kluweronline.com/art.pdf?issn=0001-8244&volume=33&page=513 |access-date=2009-08-16 |last1=Mineur |first1=Y. S. |last2=Prasol |first2=D. J. |last3=Belzung |first3=C |last4=Crusio |first4=W. E. |s2cid=20402648 }}{{Dead link|date=October 2021 |bot=InternetArchiveBot |fix-attempted=yes }} anxiety,{{cite journal |title=Effects of unpredictable chronic mild stress on anxiety and depression-like behavior in mice |journal=Behavioural Brain Research |volume=175 |issue=1 |pages=43–50 |date=November 2006 |pmid=17023061 |doi=10.1016/j.bbr.2006.07.029 |last1=Mineur |first1=Y. S. |last2=Belzung |first2=C |last3=Crusio |first3=W. E. |s2cid=28014881 |doi-access=free }}{{cite book | url=https://books.google.com/books?id=a2DVctEczBMC&pg=PT16 | title=Mouse Behavioral Testing: How to Use Mice in Behavioral Neuroscience | publisher=Academic Press | author=Wahlsten, Douglas | year=2010 | pages=166 | isbn=9780123756756 | access-date=6 February 2015 | archive-date=3 June 2016 | archive-url=https://web.archive.org/web/20160603191737/https://books.google.com/books?id=a2DVctEczBMC&pg=PT16 | url-status=live }} depressive-like behaviors, and learning,{{cite journal |title=Functional implications of decreases in neurogenesis following chronic mild stress in mice |journal=Neuroscience |volume=150 |issue=2 |pages=251–259 |date=December 2007 |pmid=17981399 |doi=10.1016/j.neuroscience.2007.09.045 |last1=Mineur |first1=Y. S. |last2=Belzung |first2=C |last3=Crusio |first3=W. E. |s2cid=25560162 }} with a concomitant drop in neurogenesis. However, the results were strain- and sex-specific and there did not appear to be a clear-cut correlation between the different changes, so that they finally concluded that although their data do not disprove the idea that deficits in hippocampal neurogenesis solely underlie the behavioral impairments observed in human psychiatric disorders such as depression, they do not provide support for this hypothesis either.
= Mouse model of autism =
More recently, Crusio has been investigating the possibility that Fmr1 knockout mice might perhaps be used as a model for autism. This idea is based on the fact that patients suffering from the Fragile X syndrome, caused by a deficiency of the FMR1 gene often show autistic symptoms. A good mouse model for the Fragile X syndrome is available in the form of mice in which the Fmr1 gene (the mouse homologue of the human FMR1 gene) has been invalidated.{{cite journal |author=The Dutch-Belgian Fragile X Consortium |title=Fmr1 knockout mice: a model to study fragile X mental retardation |journal=Cell |volume=78 |issue=1 |pages=23–33 |date=July 1994 |pmid=8033209 |doi= 10.1016/0092-8674(94)90569-X|s2cid=29674883 }} A review of the findings obtained with these mice in many different laboratories did indeed indicate that these animals display autistic-like symptoms,{{cite journal |title=Fmr1 KO mice as a possible model of autistic features |journal=The Scientific World Journal |volume=6 |pages=1164–1176 |year=2006 |pmid=16998604 |doi=10.1100/tsw.2006.220 |last1=Bernardet |first1=M |last2=Crusio |first2=W. E. |pmc=5917219 |doi-access=free }} especially changes in social behavior, a key symptom of autism.{{cite journal |title=Social behavior deficits in the Fmr1 mutant mouse |journal=Behavioural Brain Research |volume=168 |issue=1 |pages=172–175 |date=March 2006 |pmid=16343653 |doi=10.1016/j.bbr.2005.11.004 |last1=Mineur |first1=Y. S. |last2=Huynh |first2=L. X. |last3=Crusio |first3=W. E. |s2cid=45731129 }}{{cite journal |title=Altered anxiety-related and social behaviors in the Fmr1 knockout mouse model of fragile X syndrome |journal=Genes, Brain and Behavior |volume=4 |issue=7 |pages=420–430 |date=October 2005 |pmid=16176388 |doi=10.1111/j.1601-183X.2005.00123.x |last1=Spencer |first1=C. M. |last2=Alekseyenko |first2=O |last3=Serysheva |first3=E |last4=Yuva-Paylor |first4=L. A. |last5=Paylor |first5=R |s2cid=9094269 |doi-access=free }}
Editorial activities
Crusio is the founding editor-in-chief of Genes, Brain and Behavior, which he edited from 2001 to 2011.{{cite journal |author=Pagel, Mark |date=7 May 2004 |title=The order in a billion sequences |url=http://www.timeshighereducation.co.uk/story.asp?storyCode=188536§ioncode=26 |journal=Times Higher Education |access-date=2010-07-09 |archive-date=3 April 2012 |archive-url=https://web.archive.org/web/20120403011355/http://www.timeshighereducation.co.uk/story.asp?storyCode=188536§ioncode=26 |url-status=live }} The standards for the publication of mouse mutant studies that he and his co-editors developed for this journal{{cite journal |title=Standards for the publication of mouse mutant studies |journal=Genes, Brain and Behavior |volume=8 |issue=1 |pages=1–4 |date=February 2009 |pmid=18778401 |doi=10.1111/j.1601-183X.2008.00438.x|last1=Crusio |first1=W. E. |last2=Goldowitz |first2=D |last3=Holmes |first3=A |last4=Wolfer |first4=D |s2cid=205853147 |doi-access=free }} are gradually being accepted in the field.{{cite journal |title=Author Guidelines |journal=European Journal of Neuroscience |doi=10.1111/(ISSN)1460-9568|citeseerx = 10.1.1.721.6506}}{{cite journal|title=Troublesome variability in mouse studies|journal=Nature Neuroscience|date=September 2009|last=Editorial|volume=12|issue=9|page=1075|pmid=19710643 |doi=10.1038/nn0909-1075|doi-access=free}}{{cite web |title=Preparing your manuscript – Research – Criteria |url=https://behavioralandbrainfunctions.biomedcentral.com/submission-guidelines/preparing-your-manuscript/research |website=Behavioral and Brain Functions |publisher=BioMed Central |access-date=2020-05-05 |archive-date=3 June 2021 |archive-url=https://web.archive.org/web/20210603221106/https://behavioralandbrainfunctions.biomedcentral.com/submission-guidelines/preparing-your-manuscript/research |url-status=live }} Since 2017, Crusio is the editor-in-chief of Behavioral and Brain Functions{{cite web |url=https://behavioralandbrainfunctions.biomedcentral.com/about/editorial-board |title=Editorial Board |website=Behavioral and Brain Functions |publisher=BioMed Central |access-date=2017-08-25 |archive-date=19 September 2020 |archive-url=https://web.archive.org/web/20200919091620/https://behavioralandbrainfunctions.biomedcentral.com/about/editorial-board |url-status=live }} and since 2019 co-editor of Advances in Experimental Medicine and Biology.{{cite web |title=Advances in Experimental Medicine and Biology |url=https://www.springer.com/series/5584 |publisher=Springer Nature |access-date=2019-10-30 |archive-date=30 November 2019 |archive-url=https://web.archive.org/web/20191130033416/https://www.springer.com/series/5584 |url-status=live }} He is also an academic editor of PLoS ONE and served as associate editor of Behavioral and Brain Sciences (1991–2008) and The Scientific World Journal (2002-2011). Crusio serves or has served on the editorial boards of Behavioral and Brain Functions, Behavior Genetics (1991–1995), Behavioural Brain Research (1997–2007), BMC Neuroscience, BMC Research Notes, Frontiers in Behavioral Neuroscience, Journal of Visualized Experiments, Molecular Brain (2012-2017), Neurogenetics (1998–2006), Physiology and Behavior, and Current Opinion in Behavioral Sciences. He edited special issues for the journals Behavior Genetics,{{cite journal |editor=Crusio WE |title=Special issue: The neurobehavioral genetics of aggression |journal=Behavior Genetics |volume=26 |issue=5 |pages=459–504 |date=September 1996 |doi=10.1007/BF02359749 |pmid=8917943 |url=https://link.springer.com/journal/10519/26/5/page/1 |access-date=2009-08-14 |author=Crusio, Wim E. |s2cid=31579336 |archive-date=25 August 2017 |archive-url=https://web.archive.org/web/20170825020013/https://link.springer.com/journal/10519/26/5/page/1 |url-status=live }} Behavioural Brain Research,{{cite journal |editor=Crusio WE |title=Special issue: The genetic dissection of brain-behaviour relationships: An introduction to neurobehavioural genetics |journal=Behavioural Brain Research |volume=95 |issue=1 |pages=1–142 |date=September 1998 |doi=10.1016/S0166-4328(97)00203-9 |s2cid=208791454 |url=http://www.sciencedirect.com/science/journal/01664328/95/1 |access-date=2009-08-14 |archive-date=13 March 2013 |archive-url=https://web.archive.org/web/20130313202627/http://www.sciencedirect.com/science/journal/01664328/95/1 |url-status=live }} Physiology and Behavior (with Robert Gerlai),{{cite journal |veditors=Gerlai RT, Crusio WE |title=Special issue: Bridging the gap from gene to behavior: Recombinant DNA techniques merge with behavioral neurobiology |journal=Physiology and Behavior |volume=73 |issue=5 |pages=671–886 |date=August 2001 |doi=10.1016/S0031-9384(01)00583-2 |url=http://www.sciencedirect.com/science/journal/00319384/73/5 |access-date=2009-08-14 |last1=Gerlai |first1=Robert T. |s2cid=54311109 |archive-date=24 September 2015 |archive-url=https://web.archive.org/web/20150924193457/http://www.sciencedirect.com/science/journal/00319384/73/5 |url-status=live }} Hippocampus (with Aryeh Routtenberg),{{cite journal |veditors=Routtenberg A, Crusio WE |title=Special Issue: Gene Targeting and Hippocampal Function |journal=Hippocampus |volume=12 |issue=1 |pages=2–3 |date=February 2001 |doi=10.1002/hipo.10001 |pmid=11918284 |url=http://onlinelibrary.wiley.com/doi/10.1002/hipo.v12:1/issuetoc |access-date=2009-08-14 |last1=Crusio |first1=Wim E. |last2=Routtenberg |first2=Aryeh |s2cid=37535269 |archive-date=22 October 2012 |archive-url=https://web.archive.org/web/20121022005843/http://onlinelibrary.wiley.com/doi/10.1002/hipo.v12:1/issuetoc |url-status=live }} and Brain Research Bulletin (with Catherine Belzung and Robert Gerlai).{{cite journal |veditors=Belzung C, Crusio WE, Gerlai RT |title=Special issue: Behavioral neurogenetics, the genetic dissection of brain and behavior |journal=Brain Research Bulletin |volume=57 |issue=1 |pages=1–131 |date=January 2002 |doi=10.1016/S0361-9230(01)00629-3 |url=http://www.sciencedirect.com/science/journal/03619230/57/1 |access-date=2009-08-14 |pmid=11827730 |last1=Belzung |first1=Catherine |last2=Crusio |first2=Wim E. |last3=Gerlai |first3=Robert T. |s2cid=9742148 |archive-date=24 September 2015 |archive-url=https://web.archive.org/web/20150924194141/http://www.sciencedirect.com/science/journal/03619230/57/1 |url-status=live }} Together with Robert Gerlai he also edited a handbook on molecular genetic techniques for behavioral neuroscience.{{cite book |last1=Crusio |first1=WE |last2=Gerlai |first2=RT |title=Handbook of Molecular-Genetic Techniques for Brain and Behavior Research |publisher=Elsevier |location=Amsterdam |year=1999 |pages=xxvii+965 |isbn=978-0-444-50239-1 }}{{cite web |url=http://www.worldcat.org/identities/lccn-n99-46580 |title=Crusio, W.E.
Community service
In 1996, Crusio was one of two co-founders of the International Behavioural and Neural Genetics Society,{{cite web |url=http://www.ibangs.org/mc/page.do?sitePageId=83923&orgId=ibngs |title=IBANGS History |work=IBANGS Homepage |access-date=2009-04-01 |archive-date=26 July 2011 |archive-url=https://web.archive.org/web/20110726164433/http://www.ibangs.org/mc/page.do?sitePageId=83923&orgId=ibngs |url-status=dead }} for which he served as member-at-large of the executive committee, treasurer, and president (1998–2001).{{cite web|url=http://www.ibangs.org/index.php?option=com_content&view=article&id=46|title=Past Officers and Executive Committee Members|access-date=9 March 2012|archive-date=9 March 2012|archive-url=https://web.archive.org/web/20120309151802/http://www.ibangs.org/index.php?option=com_content&view=article&id=46|url-status=live}} In 2011 he received from this society the "Distinguished Service Award",{{cite web |url=http://www.ibangs.org/mc/page.do?sitePageId=83207&orgId=ibngs |title=IBANGS Awards |work=IBANGS Homepage |access-date=2011-11-25 |archive-date=1 October 2011 |archive-url=https://web.archive.org/web/20111001232515/http://www.ibangs.org/mc/page.do?sitePageId=83207 |url-status=dead }} which is given for exceptional contributions to the field of behavioral neurogenetics.{{cite web |url=http://www.ibangs.org/mc/page.do?sitePageId=93495&orgId=ibngs |title=Call for 2011 IBANGS award nominations |work=IBANGS Homepage |access-date=2011-11-25 |archive-date=1 October 2011 |archive-url=https://web.archive.org/web/20111001234436/http://www.ibangs.org/mc/page.do?sitePageId=93495 |url-status=dead }} Crusio also served on the executive committees of the Behavior Genetics Association (from which he resigned in protest to Glayde Whitney's 1995 presidential address),{{cite book |editor1-first=Yong-Kyu |editor1-last=Kim |last1=Loehlin |first1=John |title=Handbook of Behavior Genetics |chapter=History of behavior genetics |publisher=Springer |location=Berlin |isbn=978-0-387-76726-0 |pages=3–11 |chapter-url=https://books.google.com/books?id=T3P_SLtfIN0C&q=crusio+%22glayde+whitney%22&pg=PA11 |date=2009-04-01 |access-date=17 December 2020 |archive-date=2 October 2021 |archive-url=https://web.archive.org/web/20211002112040/https://books.google.com/books?id=T3P_SLtfIN0C&q=crusio+%22glayde+whitney%22&pg=PA11 |url-status=live }}{{cite book | date=2014 | first1=Aaron | isbn=978-0-226-05831-3 | last1=Panofsky | title=Misbehaving Science. Controversy and the Development of Behavior Genetics | publisher=University of Chicago Press | location=Chicago | pages=3–4}} the European Brain and Behaviour Society,{{cite web|url=http://www.ebbs-science.org/cms/general/committee-members.html|title=Past committee members|access-date=2009-08-11|archive-date=14 March 2012|archive-url=https://web.archive.org/web/20120314123152/http://www.ebbs-science.org/cms/general/committee-members.html|url-status=live}} and the International Behavioral Neuroscience Society,{{cite web |url=http://www.ibnshomepage.org/history.htm |title=IBNS History of Officers |access-date=2009-08-11 |archive-date=21 November 2008 |archive-url=https://web.archive.org/web/20081121061052/http://www.ibnshomepage.org/history.htm |url-status=dead }} and has been a President of the Dutch Behavior Genetics Contact Group.{{cite journal |title=Obituary Sjeng Kerbusch (1947-1991) |journal=Behavior Genetics |year=1991 |first=W.E. |last=Crusio |volume=21 |issue=5 |pages=431–432 |doi=10.1007/BF01066721 |s2cid=148069790 |doi-access=free }} He has been a member of several program committees for scientific meetings, most notably the 8th and 10th{{cite web |url=http://www.wcpg2002.be/ |title=Xth World Congress on Psychiatric Genetics – Committees |access-date=2010-07-09 |archive-url = https://web.archive.org/web/20020930114155/http://www.wcpg2002.be/ |archive-date = 30 September 2002}} World Congresses of Psychiatric Genetics and the 2008, 2009 (co-chair), 2010 (chair), and 2011 (chair) Annual Meetings of the IBNS.{{cite web |url=http://www.ibnshomepage.org/committees.htm |title=IBNS Committees/Mission Statements |access-date=2009-08-11 |archive-date=4 May 2009 |archive-url=https://web.archive.org/web/20090504005059/http://www.ibnshomepage.org/committees.htm |url-status=dead }}
Significant papers
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According to Google Scholar, Crusio's works have been cited over 10,000 times and he has an h-index of 46.{{cite web |title=Wim Crusio |url=https://scholar.google.com/citations?user=7qhmlzwAAAAJ&hl=en |website=Google Scholar |access-date=2022-05-16}} Some significant papers are:
- {{cite journal |title=A quantitative-genetic analysis of hippocampal variation in the mouse |journal=Journal of Neurogenetics |volume=21 |issue=4; Special Retrospective Issue: The Origins of Neurogenetics |pages=197–208 |year=2007 |pmid=18161583 |doi=10.1080/01677060701715827 |last1=Crusio |first1=W. E. |last2=Genthner-Grimm |first2=G. |last3=Schwegler |first3=H.|s2cid=7334116 }} Original publication: {{cite journal |journal=Journal of Neurogenetics |volume=3 |issue=4 |pages=203–214 |date=July 1986 |pmid=3746523 |doi= 10.3109/01677068609106850|title=A quantitative-genetic analysis of hippocampal variation in the mouse |last1=Crusio |first1=W. E. |last2=Genthner-Grimm |first2=G. |last3=Schwegler |first3=H.}}
- {{cite journal |title=Radial-maze performance and structural variation of the hippocampus in mice: a correlation with mossy fibre distribution |journal=Brain Research |volume=425 |issue=1 |pages=182–185 |date=November 1987 |pmid=3427419 |doi=10.1016/0006-8993(87)90498-7 |last1=Crusio |first1=W. E. |last2=Schwegler |first2=H. |last3=Lipp |first3=H. P.|s2cid=39198617 }}
- {{cite journal |title=Behavioral responses to novelty and structural variation of the hippocampus in mice. II. Multivariate genetic analysis |journal=Behavioural Brain Research |volume=32 |issue=1 |pages=81–88 |date=February 1989 |pmid=2930637 |doi=10.1016/S0166-4328(89)80075-0|last1=Crusio |first1=W. E. |last2=Schwegler |first2=H. |last3=van Abeelen |first3=J. H. F.|s2cid=42291976 }}
- {{cite journal |author=Crusio W. E. |title=Genetic dissection of mouse exploratory behaviour |journal=Behavioural Brain Research |volume=125 |issue=1–2 |pages=127–132 |date=November 2001 |pmid=11682103 |doi= 10.1016/S0166-4328(01)00280-7|s2cid=28031277 }}
- {{cite journal |title=Standards for the publication of mouse mutant studies |journal=Genes, Brain and Behavior |volume=8 |issue=1 |pages=1–4 |date=February 2009 |pmid=18778401 |doi=10.1111/j.1601-183X.2008.00438.x|last1=Crusio |first1=W. E. |last2=Goldowitz |first2=D. |last3=Holmes |first3=A. |last4=Wolfer |first4=D.|s2cid=205853147 |doi-access=free }}
References
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External links
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- {{cite web |url=http://www.incia.u-bordeaux1.fr/spip.php?article168 |title=Crusio Wim |publisher=The Aquitaine Institute for Cognitive and Integrative Neuroscience |work=Homepage |access-date=2012-01-12 |archive-date=21 October 2014 |archive-url=https://web.archive.org/web/20141021164838/http://www.incia.u-bordeaux1.fr/spip.php?article168 |url-status=dead }}
- {{cite web|url=https://scholar.google.com/citations?user=7qhmlzwAAAAJ |title=Wim Crusio – Google Scholar Citations |publisher=Google Scholar |access-date=2013-10-10}}
{{Authority control}}
{{DEFAULTSORT:Crusio, Wim}}
Category:Scientific journal editors
Category:Dutch neuroscientists
Category:20th-century Dutch biologists
Category:21st-century Dutch biologists
Category:People from Bergen op Zoom
Category:Radboud University Nijmegen alumni
Category:UMass Chan Medical School faculty
Category:Botanists with author abbreviations
Category:French National Centre for Scientific Research scientists
Category:20th-century Dutch botanists
Category:21st-century Dutch botanists
Category:Founders of learned societies