Yoshito Kishi
{{Short description|Japanese chemistry professor (1937–2023)}}
{{Eastern name order|Kishi Yoshito}}
{{Infobox scientist
| name = Yoshito Kishi
| birth_name =
| image = Yoshito Kishi 2002 2003.jpg
| caption = Kishi in 2003
| birth_date = {{birth date|1937|4|13|df=y}}
| death_date = {{death date and age|2023|1|9|1937|4|13|df=y}}
| death_place =
| field = Organic chemistry
| work_institutions = Nagoya University
Harvard University
| alma_mater = Nagoya University (BS, PhD)
| doctoral_advisor = Yoshimasa Hirata
| doctoral_students = Tohru Fukuyama
Stuart L. Schreiber
| thesis_title = ウミホタルルシフェリンの構造とその全合成
| thesis_url = https://m-opac.nul.nagoya-u.ac.jp/webopac/WB03272929
| thesis_year = 1966
| notable_students = René Peters (chemist)
| known_for =
| awards =
| spouse =
| website =
}}
{{Nihongo|Yoshito Kishi|岸 義人|Kishi Yoshito|13 April 1937 – 9 January 2023}}[https://www.nikkei.com/article/DGXZQOUE1221O0S3A110C2000000/ 岸義人氏が死去 天然物有機化学者] {{in lang|ja}} was a Japanese chemist who was the Morris Loeb Professor of Chemistry at Harvard University. He was known for his contributions to the sciences of organic synthesis and total synthesis.
Early life and education
Kishi was born in Nagoya, Japan and attended Nagoya University, where he obtained both his BS and PhD degrees.{{cite journal |last1=Williams |first1=Robert M. |title=Preface: Honoring the 70th Birthday of Professor Yoshito Kishi |journal=Heterocycles |date=2007 |volume=72 |issue=1 |page=1–3 |doi=10.3987/2007-72-0001 |url=https://www.heterocycles.jp/newlibrary/downloads/PDF/00089/72/1 |access-date=26 February 2023|doi-access=free }}{{cite journal | last1 = Kishi | first1 = Yoshito | last2 = Rando | first2 = Robert R. | title = Structural Basis of Protein Kinase C Activation by Tumor Promoters | journal = Accounts of Chemical Research | volume = 31 | pages = 9672–6 | year = 1998 | doi = 10.1021/ar9600751 | issue = 4| pmc = 298563 | pmid=2602368}} He was a postdoctoral research fellow at Harvard University where he worked with Robert Burns Woodward. From 1966 through 1974, he was a professor of chemistry at Nagoya University. Since 1974, Kishi had been a professor of chemistry at Harvard University.{{cite news |last1=Chaudhry |first1=Yahya |title=Yoshito Kishi, 86, remembered for developing important anti-cancer agent |url=https://news.harvard.edu/gazette/story/2023/01/yoshito-kishi-86-remembered-for-developing-important-anti-cancer-agent/ |access-date=26 February 2023 |work=Harvard Gazette |date=31 January 2023 |language=en}}{{cite news |last1=Wang |first1=Austin H. |title=Yoshito Kishi, Organic Chemist Who Climbed 'Mount Everest' of Synthesis, Dies at 85 |url=https://www.thecrimson.com/article/2023/3/21/yoshito-kishi-obituary/ |access-date=25 March 2023 |work=Harvard Crimson |date=21 March 2023}}
Kishi's research has focused on the total synthesis of complex natural products. The accomplishments of his research group include the total syntheses of palytoxin, mycolactones, halichondrins, saxitoxin, tetrodotoxin, geldanamycin, batrachotoxin and many others.[http://www.chem.harvard.edu/research/faculty/yoshito_kishi.php Yoshito Kishi] {{webarchive |url=https://web.archive.org/web/20101018045129/http://www.chem.harvard.edu/research/faculty/yoshito_kishi.php |date=October 18, 2010 }}, Department of Chemistry and Chemical Biology, Harvard University{{cite journal |last1=Lowe |first1=Derek |title=Prof. Yoshito Kishi, 1937-2023 |journal=Science |date=January 18, 2023 |url=https://www.science.org/content/blog-post/prof-yoshito-kishi-1937-2023 |access-date=26 February 2023 |language=en}}{{cite journal |last1=Krietsch Boerner |first1=Leigh |title=Organic chemist Yoshito Kishi dies at 85 |journal=Chemical & Engineering News |date=January 24, 2023 |volume=101 |issue=4 |url=https://cen.acs.org/people/obituaries/Organic-chemist-Yoshito-Kishi-dies-85/101/web/2023/01 |access-date=26 February 2023}} Kishi has also contributed to the development of new chemical reactions including the Nozaki–Hiyama–Kishi reaction.{{cite journal | last1 = Takai | first1 = K. | last2 = Tagashira | first2 = M. | last3 = Kuroda | first3 = T. | last4 = Oshima | first4 = K. | last5 = Utimoto | first5 = K. | last6 = Nozaki | first6 = H. | title = Reactions of alkenylchromium reagents prepared from alkenyl trifluoromethanesulfonates (triflates) with chromium(II) chloride under nickel catalysis | journal = Journal of the American Chemical Society | volume = 108 | pages = 6048–50 | year = 1986 | doi = 10.1021/ja00279a068 | issue = 19 | pmid=22175376| bibcode = 1986JAChS.108.6048T }}
Recognition
- 1999 Imperial Prize of the Japan Academy
- 2001 Tetrahedron Prize for Creativity in Organic Chemistry & BioMedicinal Chemistry {{cite web|url=http://www.elsevier.com/physical-sciences/chemistry/organic-chemistry/tetrahedron-prize-for-creativity-in-organic-chemistry-or-bioorganic-medicinal-chemistry |title=Tetrahedron Prize for Creativity in Organic Chemistry or Bioorganic & Medicinal Chemistry |publisher=Elsevier |access-date=28 January 2015 |url-status=dead |archive-url=https://web.archive.org/web/20140909101444/http://www.elsevier.com/physical-sciences/chemistry/organic-chemistry/tetrahedron-prize-for-creativity-in-organic-chemistry-or-bioorganic-medicinal-chemistry |archive-date=September 9, 2014 }}
- 2001 Ernest Guenther Award
- 2001 Person of Cultural Merit
- 2013 Order of the Sacred Treasure
- 2018 Ryoji Noyori Prize
See also
References
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Category:21st-century American chemists
Category:Japanese organic chemists
Category:Nagoya University alumni
Category:Academic staff of Nagoya University
Category:Harvard University faculty
Category:Fellows of the American Academy of Arts and Sciences