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CSRP2BP

{{Short description|Protein-coding gene in humans}}

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CSRP2 binding protein is a protein that in humans is encoded by the CSRP2BP gene.{{cite web | title = Entrez Gene: CSRP2 binding protein| url = https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=retrieve&list_uids=57325| access-date = 2011-09-20 }}

CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse function. CSRP2 and some related proteins are thought to act as protein adapters, bridging two or more proteins to form a larger protein complex. The protein encoded by this gene binds to one of the LIM domains of CSRP2 and contains an acetyltransferase domain. Although the encoded protein has been detected in the cytoplasm, it is predominantly a nuclear protein. Alternatively spliced transcript variants have been described.{{cite web | title = Entrez Gene: CSRP2 binding protein| url = https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=retrieve&list_uids=57325| access-date = 2011-09-20 }}

References

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External links

  • {{UCSC gene info|CSRP2BP}}

Further reading

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{{cite journal | vauthors = Weiskirchen R, Gressner AM | title = The cysteine- and glycine-rich LIM domain protein CRP2 specifically interacts with a novel human protein (CRP2BP) | journal = Biochemical and Biophysical Research Communications | volume = 274 | issue = 3 | pages = 655–663 | date = August 2000 | pmid = 10924333 | doi = 10.1006/bbrc.2000.3187 }}

{{cite journal | vauthors = Wang YL, Faiola F, Xu M, Pan S, Martinez E | title = Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein | journal = The Journal of Biological Chemistry | volume = 283 | issue = 49 | pages = 33808–33815 | date = December 2008 | pmid = 18838386 | pmc = 2590711 | doi = 10.1074/jbc.M806936200 | doi-access = free }}

{{cite journal | vauthors = Guelman S, Kozuka K, Mao Y, Pham V, Solloway MJ, Wang J, Wu J, Lill JR, Zha J | title = The double-histone-acetyltransferase complex ATAC is essential for mammalian development | journal = Molecular and Cellular Biology | volume = 29 | issue = 5 | pages = 1176–1188 | date = March 2009 | pmid = 19103755 | pmc = 2643826 | doi = 10.1128/MCB.01599-08 }}

{{cite journal | vauthors = Wang K, Zhang H, Bloss CS, Duvvuri V, Kaye W, Schork NJ, Berrettini W, Hakonarson H | title = A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa | journal = Molecular Psychiatry | volume = 16 | issue = 9 | pages = 949–959 | date = September 2011 | pmid = 21079607 | doi = 10.1038/mp.2010.107 | s2cid = 15188506 | url = http://nrs.harvard.edu/urn-3:HUL.InstRepos:11879352 }}

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Category:Genes mutated in mice

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