acetoin dehydrogenase

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = Acetoin dehydrogenase

| EC_number = 2.3.1.190

| CAS_number =

| GO_code =

| image =

| width =

| caption =

}}

Acetoin dehydrogenase ({{EC number|2.3.1.190}}, acetoin dehydrogenase complex, acetoin dehydrogenase enzyme system, AoDH ES) is an enzyme with systematic name acetyl-CoA:acetoin O-acetyltransferase.{{cite journal | vauthors = Priefert H, Hein S, Krüger N, Zeh K, Schmidt B, Steinbüchel A | title = Identification and molecular characterization of the Alcaligenes eutrophus H16 aco operon genes involved in acetoin catabolism | journal = Journal of Bacteriology | volume = 173 | issue = 13 | pages = 4056–71 | date = July 1991 | pmid = 2061286 | pmc = 208054 | doi = 10.1128/jb.173.13.4056-4071.1991 }}{{cite journal | vauthors = Oppermann FB, Steinbüchel A | title = Identification and molecular characterization of the aco genes encoding the Pelobacter carbinolicus acetoin dehydrogenase enzyme system | journal = Journal of Bacteriology | volume = 176 | issue = 2 | pages = 469–85 | date = January 1994 | pmid = 8110297 | pmc = 205071 | doi = 10.1128/jb.176.2.469-485.1994 }}{{cite journal | vauthors = Krüger N, Oppermann FB, Lorenzl H, Steinbüchel A | title = Biochemical and molecular characterization of the Clostridium magnum acetoin dehydrogenase enzyme system | journal = Journal of Bacteriology | volume = 176 | issue = 12 | pages = 3614–30 | date = June 1994 | pmid = 8206840 | pmc = 205551 | doi = 10.1128/jb.176.12.3614-3630.1994 }}{{cite journal | vauthors = Huang M, Oppermann FB, Steinbüchel A | title = Molecular characterization of the Pseudomonas putida 2,3-butanediol catabolic pathway | journal = FEMS Microbiology Letters | volume = 124 | issue = 2 | pages = 141–50 | date = December 1994 | pmid = 7813883 | doi = 10.1111/j.1574-6968.1994.tb07276.x | doi-access = free }}{{cite journal | vauthors = Huang M, Oppermann-Sanio FB, Steinbüchel A | title = Biochemical and molecular characterization of the Bacillus subtilis acetoin catabolic pathway | journal = Journal of Bacteriology | volume = 181 | issue = 12 | pages = 3837–41 | date = June 1999 | pmid = 10368162 | pmc = 93865 }} This enzyme catalyses the following chemical reaction

: acetoin + CoA + NAD⁺ $\backslash rightleftharpoons$ acetaldehyde + acetyl-CoA + NADH + H⁺

This enzyme requires thiamine diphosphate.