alkylhalidase

{{infobox enzyme

| Name = alkylhalidase

| EC_number = 3.8.1.1

| CAS_number = 9025-22-3

| GO_code = 0047651

| image =

| width =

| caption =

}}

In enzymology, an alkylhalidase ({{EC number|3.8.1.1}}) is an enzyme that catalyzes the chemical reaction

:bromochloromethane + H2O \rightleftharpoons formaldehyde + bromide + chloride

Thus, the two substrates of this enzyme are bromochloromethane and H2O, whereas its 3 products are formaldehyde, bromide, and chloride.

This enzyme belongs to the family of hydrolases, specifically those acting on halide bonds in carbon-halide compounds. The systematic name of this enzyme class is alkyl-halide halidohydrolase. Other names in common use include halogenase, haloalkane halidohydrolase, and haloalkane dehalogenase.

References

{{reflist|1}}

  • {{cite journal|vauthors=Heppel LA, Porterfield VT|title=Enzymatic dehalogenation of certain brominated and chlorinated compounds|journal=The Journal of Biological Chemistry|volume=176|issue=2|pages=763–9|date=November 1948|pmid=18889931|url=http://www.jbc.org/content/176/2/763.full.pdf|format=PDF}}{{Open access}}

Further reading

  • {{Cite book|title=Enzyme Functionality: Design: Engineering, and Screening|last=Damborský|first=Jiří|display-authors=et al|publisher=CRC Press|year=2003|isbn=9780203913048|editor-last=Svendsen|editor-first=Allan|chapter=Rational Redesign of Haloalkane Dehalogenases by Comparative Binding Energy Analysis|oclc=839656924}}

{{enzymes}}

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Category:EC 3.8.1

Category:Enzymes of unknown structure

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