anti-Jo1

Anti-Jo1 is an anti-nuclear antibody.{{cite journal |author1=Gutiérrez-Ramos R |author2=Gonzalez-Díaz V |author3=Pacheco-Tovar MG |author4=López-Luna A |author5=Avalos-Díaz E |author6=Herrera-Esparza R |title=A dermatomyositis and scleroderma overlap syndrome with a remarkable high titer of anti-exosome antibodies |journal=Reumatismo |volume=60 |issue=4 |pages=296–300 |year=2008 |pmid=19132155 |doi= 10.4081/reumatismo.2008.296|url=http://www.reumatismo.org/admin/filesArticoli/60-4-296.pdf|doi-access=free }}{{cite journal |author1=Zold E |author2=Szodoray P |author3=Gaal J |display-authors=etal |title=Vitamin D deficiency in undifferentiated connective tissue disease |journal=Arthritis Res. Ther. |volume=10 |issue=5 |pages=R123 |year=2008 |pmid=18928561 |pmc=2592813 |doi=10.1186/ar2533 |doi-access=free }}

Anti-Jo1 has been associated with inflammatory myopathies such as polymyositis, dermatomyositis and antisynthetase syndrome.{{cite journal |author1=Kalenian M |author2=Zweiman B |title=Inflammatory myopathy, bronchiolitis obliterans/organizing pneumonia, and anti-Jo-1 antibodies--an interesting association |journal=Clinical and Diagnostic Laboratory Immunology |volume=4 |issue=2 |pages=236–40 |date=March 1997 |pmid=9067664 |pmc=170510 |doi= 10.1128/CDLI.4.2.236-240.1997|url=}}{{cite web |title=Antisynthetase syndrome |url=https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=81 |website=Orphanet |accessdate=20 March 2019}}

It has histidine-tRNA ligase as a target.

References

Category:Autoantibodies