aquayamycin
{{chembox
| verifiedrevid = 458036550
| ImageFile=Aquayamycin.svg
| ImageSize=150px
| PIN=(3R,4aR,12bS)-9-[(2R,4R,5S,6R)-4,5-Dihydroxy-6-methyloxan-2-yl]-3,4a,8,12b-tetrahydroxy-3-methyl-3,4,4a,12b-tetrahydrotetraphene-1,7,12(2H)-trione
| OtherNames=
| Reference=[https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=73441 Aquayamycin - Compound Summary], PubChem.
|Section1={{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|??}}
| CASNo=26055-63-0
| PubChem=73441
| SMILES=C[C@@H]1[C@H]([C@@H](C[C@@H](O1)C2=C(C3=C(C=C2)C(=O)C4=C(C3=O)C=C[C@]5([C@@]4(C(=O)C[C@](C5)(C)O)O)O)O)O)O
| MeSHName=aquayamycin
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 66147
| InChI = 1/C25H26O10/c1-10-19(28)14(26)7-15(35-10)11-3-4-12-17(20(11)29)21(30)13-5-6-24(33)9-23(2,32)8-16(27)25(24,34)18(13)22(12)31/h3-6,10,14-15,19,26,28-29,32-34H,7-9H2,1-2H3/t10-,14-,15-,19-,23+,24+,25+/m1/s1
| InChIKey = KCOULPRVOZDQEL-IFNZWHIZBY
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C25H26O10/c1-10-19(28)14(26)7-15(35-10)11-3-4-12-17(20(11)29)21(30)13-5-6-24(33)9-23(2,32)8-16(27)25(24,34)18(13)22(12)31/h3-6,10,14-15,19,26,28-29,32-34H,7-9H2,1-2H3/t10-,14-,15-,19-,23+,24+,25+/m1/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = KCOULPRVOZDQEL-IFNZWHIZSA-N
}}
|Section2={{Chembox Properties
| Formula= C25H26O10
| MolarMass= 486.47 g/mol
| Appearance=
| Density=
| MeltingPt=
| BoilingPt=
| Solubility=
}}
|Section3={{Chembox Hazards
| MainHazards=
| FlashPt=
| AutoignitionPt =
}}
}}
Aquayamycin is an anthraquinone derivative.{{Cite journal | last1 = Sezaki | first1 = M. | last2 = Kondo | first2 = S. | last3 = Maeda | first3 = K. | last4 = Umezawa | first4 = H. | last5 = Ono | first5 = M. | title = The structure of aquayamycin | doi = 10.1016/S0040-4020(01)98726-5 | journal = Tetrahedron | volume = 26 | issue = 22 | pages = 5171–5190 | year = 1970 | pmid = 5499897}}
It is an inhibitor of the enzyme tyrosine hydroxylase.
Saquayamycins (saquayamycins A, B, C and D) are antibiotics of the aquayamycin group found in Streptomyces nodosus cultures broth.{{Cite journal
| doi = 10.7164/antibiotics.38.1171
| last1 = Uchida | first1 = T.
| last2 = Imoto | first2 = M.
| last3 = Watanabe | first3 = Y.
| last4 = Miura | first4 = K.
| last5 = Dobashi | first5 = T.
| last6 = Matsuda | first6 = N.
| last7 = Sawa | first7 = T.
| last8 = Naganawa | first8 = H.
| last9 = Hamada | first9 = M.
| last10 = Takeuchi | first10 = T.
| last11 = Umezawa | first11 = H.
| title = Saquayamycins, new aquayamycin-group antibiotics
| journal = The Journal of Antibiotics
| volume = 38
| issue = 9
| pages = 1171–1181
| year = 1985
| pmid = 3840796
| doi-access = free
}}
References
{{Reflist}}
{{Monoamine metabolism modulators}}
Category:Anthraquinone glycosides
Category:Tyrosine hydroxylase inhibitors
{{nervous-system-drug-stub}}