aurein

{{Infobox protein family

| Symbol = Antimicrobial20

| Name = Antimicrobial20

| image =

| width =

| caption =

| Pfam = PF08256

| Pfam_clan =

| InterPro = IPR013157

| SMART =

| PROSITE =

| MEROPS =

| SCOP =

| TCDB = 1.C.76

| OPM family = 211

| OPM protein = 1vm5

| CAZy =

| CDD =

}}

This family of antibacterial peptides are secreted from the granular dorsal glands of Litoria aurea (Green and golden bell frog), Litoria raniformis (Southern bell frog), Litoria citropa (Australian blue mountains tree frog) and frogs from genus Uperoleia. Amongst the more active of these are aurein 1.2,{{Cite web |title=Differential Stability of Aurein 1.2 Pores in Model Membranes of Two Probiotic Strains |url=http://dx.doi.org/10.1021/acs.jcim.0c00855.s001 |access-date=2023-10-03 |doi=10.1021/acs.jcim.0c00855.s001 }} aurein 2.2 and aurein 3.1; caerin 1.1, maculatin 1.1, uperin 3.6;{{cite journal |vauthors=Rozek T, Wegener KL, Bowie JH, Olver IN, Carver JA, Wallace JC, Tyler MJ | title = The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2 >| journal = Eur. J. Biochem. | volume = 267 | issue = 17 | pages = 5330–41 |date=September 2000 | pmid = 10951191 | doi = 10.1046/j.1432-1327.2000.01536.x}} citropin 1.1, citropin 1.2, citropin 1.3 and a minor peptide are wide-spectrum antibacterial peptides.{{cite journal |vauthors=Wegener KL, Wabnitz PA, Carver JA, Bowie JH, Chia BC, Wallace JC, Tyler MJ | title = Host defence peptides from the skin glands of the Australian blue mountains tree-frog Litoria citropa. Solution structure of the antibacterial peptide citropin 1.1 | journal = Eur. J. Biochem. | volume = 265 | issue = 2 | pages = 627–37 |date=October 1999 | pmid = 10504394 | doi = 10.1046/j.1432-1327.1999.00750.x| doi-access = free }}{{cite journal |last1=Shahmiri |first1=Mahdi |last2=Enciso |first2=Marta |last3=Mechler |first3=Adam |title=Controls and constrains of the membrane disrupting action of Aurein 1.2 |journal=Scientific Reports |date=17 November 2015 |volume=5 |issue=1 |pages=16378 |doi=10.1038/srep16378 |pmid=26574052 |pmc=4648102 |bibcode=2015NatSR...516378S }}