bencyclane

{{chembox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 459531065

| ImageFile = Bencyclane.svg

| ImageAlt = Structural formula of bencyclane

| ImageFile1 = Bencyclane 3D ball.png

| ImageAlt1 = Ball-and-stick model of the bencyclane molecule

| IUPACName=3-[(1-benzylcycloheptyl)oxy]-N,N-dimethylpropan-1-amine

| OtherNames=

|Section1={{Chembox Identifiers

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 6I97Z6S135

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 2222

| ChEMBL_Ref = {{ebicite|changed|EBI}}

| ChEMBL = 2110767

| InChI = 1/C19H31NO/c1-20(2)15-10-16-21-19(13-8-3-4-9-14-19)17-18-11-6-5-7-12-18/h5-7,11-12H,3-4,8-10,13-17H2,1-2H3

| InChIKey = FYJJXENSONZJRG-UHFFFAOYAM

| CASNo_Ref = {{cascite|changed|??}}

| CASNo=2179-37-5

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C19H31NO/c1-20(2)15-10-16-21-19(13-8-3-4-9-14-19)17-18-11-6-5-7-12-18/h5-7,11-12H,3-4,8-10,13-17H2,1-2H3

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = FYJJXENSONZJRG-UHFFFAOYSA-N

| PubChem = 2312

| SMILES = O(CCCN(C)C)C1(CCCCCC1)Cc2ccccc2

}}

|Section2={{Chembox Properties

| C=19 | H=31 | N=1 | O=1

| MolarMass=289.45554

| Appearance=

| Density=

| MeltingPt=

| BoilingPt=

| Solubility=

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|Section6={{Chembox Pharmacology

| ATCCode_prefix = C04

| ATCCode_suffix = AX11

}}

|Section7={{Chembox Hazards

| MainHazards=

| FlashPt=

| AutoignitionPt =

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Bencyclane is an antispasmodic, vasodilator, and platelet aggregation inhibitor.{{cite book | title = The Dictionary of Drugs: Chemical Data, Structures and Bibliographies | editor = J. Elks | publisher = Springer | date = 2014 | url = https://books.google.com/books?isbn=1475720858 }}

Synthesis

File:Bencyclane synthesis.svg

Grignard addition of benzylmagnesiumbromide to suberone would give 1-benzylcycloheptanol [4006-73-9] (1'). Williamson ether synthesis with 3-dimethylaminopropylchloride [109-54-6] (2) completed the synthesis of bencyclane (3).

See also

References

{{Reflist}}

{{Calcium channel blockers}}

Category:Calcium channel blockers

Category:Ethers

Category:Dimethylamino compounds

{{Amine-stub}}