benproperine

{{short description|Chemical compound}}

{{Drugbox

| Watchedfields = changed

| verifiedrevid = 447813319

| IUPAC_name = (RS)-1-[2-(2-Benzylphenoxy)-1-methylethyl]piperidine

| image =Benproperine.svg

| tradename = Blascorid, Pectipront, Pirexyl, Tussafug

| Drugs.com = {{drugs.com|international|benproperine}}

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| legal_US =

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| routes_of_administration =

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| CAS_number_Ref = {{cascite|correct|??}}

| CAS_number = 2156-27-6

| CAS_supplemental = 19428-14-9 (phosphate salt)

| ATC_prefix = R05

| ATC_suffix = DB02

| PubChem = 2326

| ChEMBL = 2105910

| DrugBank_Ref = {{drugbankcite|correct|drugbank}}

| DrugBank =

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 2236

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 3AA6IZ48YK

| KEGG_Ref = {{keggcite|correct|kegg}}

| KEGG = D07512

| C=21 | H=27

| N=1 | O=1

| smiles = O(c1ccccc1Cc2ccccc2)CC(N3CCCCC3)C

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C21H27NO/c1-18(22-14-8-3-9-15-22)17-23-21-13-7-6-12-20(21)16-19-10-4-2-5-11-19/h2,4-7,10-13,18H,3,8-9,14-17H2,1H3

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = JTUQXGZRVLWBCR-UHFFFAOYSA-N

}}

Benproperine (INN) is a cough suppressant.{{cite journal | vauthors = Li Y, Zhong DF, Chen SW, Maeba I | title = Identification of some benproperine metabolites in humans and investigation of their antitussive effect | journal = Acta Pharmacologica Sinica | volume = 26 | issue = 12 | pages = 1519–26 | date = December 2005 | pmid = 16297353 | doi = 10.1111/j.1745-7254.2005.00212.x | doi-access = free }} It has been marketed in multiple countries in Central America and Europe, as the phosphate or pamoate salts in either tablet, dragée, or syrup form. Trade names include Blascorid in Italy and Sweden, Pectipront and Tussafug in Germany, and Pirexyl in Scandinavia. The recommended dosage for adults is 25 to 50 mg two to four times daily, and for children 25 mg once or twice daily. Adverse effects include dry mouth, dizziness, fatigue, and heartburn.{{cite book |isbn=0-8103-7177-4 |title=Drugs Available Abroad, 1st Edition |page=6 |date=1991 | vauthors = Schlesser JL |publisher=Derwent Publications Ltd.}}