caiA RNA motif

{{Short description|Conserved RNA structure}}

{{primary sources|date=November 2021}}

{{DISPLAYTITLE:caiA RNA motif}}

{{Infobox rfam

| Name = caiA

| image = RF02934.svg

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| caption = Consensus secondary structure and sequence conservation of caiA RNA

| Symbol = caiA

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| Rfam = RF02934

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| RNA_type = Gene; sRNA

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| SO = {{SO|0001263}}

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The caiA RNA motif is a conserved RNA structure that was discovered by bioinformatics.{{cite journal |vauthors=Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR |title=Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions |journal=Nucleic Acids Res. |volume=45 |issue=18 |pages=10811–10823 |date=October 2017 |pmid=28977401 |pmc=5737381 |doi=10.1093/nar/gkx699 }}

caiA motifs are found in Clostridiales.

caiA RNAs are found upstream of genes whose protein products function as acyl CoA dehydrogenases, although in one case the annotated substrate is butyryl-CoA. caiA RNAs might regulate these genes (i.e. function as cis-regulatory elements), but it is also possible that their association with these genes is a coincidence.