calamine

{{Short description|Cream or lotion for treating skin conditions}}

{{distinguish|Chamomile}}

{{about|the medication}}

{{Infobox drug

| drug_name =

| type = combo

| image = Calamine lotion.png

| width =

| alt = A puddle of a thin pink lotion, next to a pink plastic bottle

| caption = A puddle of calamine lotion next to a pink plastic bottle

| component1 = zinc oxide

| class1 = astringent

| component2 = ferric oxide

| class2 = antipruritic

| pronounce = {{respell|KAL|ə|mine}}

| tradename =

| Drugs.com =

| MedlinePlus =

| licence_EU =

| DailyMedID = Calamine

| licence_US =

| pregnancy_AU =

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| routes_of_administration = Topical

| ATCvet =

| ATC_prefix = D02

| ATC_suffix = AB

| ATC_supplemental =

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| legal_US = OTC

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| CAS_number = 8011-96-9

| CAS_supplemental =

| PubChem = 23083748

| IUPHAR_ligand =

| DrugBank =

| ChemSpiderID = 16112062

| UNII =

| KEGG = D03284

| ChEBI =

| ChEMBL = 3989426

| synonyms = Calamine lotion

| StdInChI=1S/2Fe.4O.Zn/q2*+3;4*-2;+2

| StdInChIKey = CPYIZQLXMGRKSW-UHFFFAOYSA-N

| SMILES = [O-2].[O-2].[O-2].[O-2].[Fe+3].[Fe+3].[Zn+2]

}}

{{wikt | calamine}}

Calamine, also known as calamine lotion, is a medication made from powdered calamine mineral that is used to treat mild itchiness.{{cite book | title = WHO Model Formulary 2008 | year = 2009 | isbn = 9789241547659 | vauthors = ((World Health Organization)) | veditors = Stuart MC, Kouimtzi M, Hill SR | hdl = 10665/44053 | author-link = World Health Organization | publisher = World Health Organization | page = 303 }} Conditions treated include sunburn, insect bites, poison ivy, poison oak, and other mild skin conditions.{{cite web|title= Aqueous Calamine Cream BP - Summary of Product Characteristics (SPC) - (eMC)|url= https://www.medicines.org.uk/emc/medicine/25283|website= www.medicines.org.uk|access-date= 29 December 2016|date= 18 November 2016|url-status= live|archive-url= https://web.archive.org/web/20161230000012/https://www.medicines.org.uk/emc/medicine/25283|archive-date=30 December 2016}} It may also help dry out secretions resulting from skin irritation.{{cite web|title= Calamine (topical) medical facts from Drugs.com|url= https://www.drugs.com/mtm/calamine-topical.html|website= www.drugs.com|url-status= live|archive-url= https://web.archive.org/web/20171107030453/https://www.drugs.com/mtm/calamine-topical.html|archive-date= 2017-11-07}} It is applied on the skin as a cream or lotion.{{cite book|title= British National Formulary: BNF 69 |date= 2015|publisher= British Medical Association|isbn= 9780857111562|page= 801|edition= 69}}

Side effects may include skin irritation. It is considered to be safe in pregnancy. Calamine is a combination of zinc oxide and 0.5% ferric oxide (Fe₂O₃). The lotion is produced with additional ingredients such as phenol and calcium hydroxide.{{cite book| vauthors = Braun-Falco O, Plewig G, Wolff HH, Burgdorf W | chapter = Topical Therapy |title= Dermatology|date= 2012|publisher= Springer Science & Business Media|isbn= 9783642979316|page= 1724|edition=2nd | chapter-url= https://books.google.com/books?id=kK_rCAAAQBAJ&pg=PA1724|language= en|url-status= live|archive-url= https://web.archive.org/web/20161229170841/https://books.google.ca/books?id=kK_rCAAAQBAJ&pg=PA1724|archive-date= 2016-12-29}}{{cite book| vauthors = Ma JK, Hadzija B | chapter = Rheology in Pharmacy |title= Basic Physical Pharmacy|date= 2012|publisher= Jones & Bartlett Publishers|isbn= 9780763757342|page= 327| chapter-url = https://books.google.com/books?id=NLabiVZSE7QC&pg=PA327|language= en|url-status= live|archive-url= https://web.archive.org/web/20161230000202/https://books.google.ca/books?id=NLabiVZSE7QC&pg=PA327|archive-date= 2016-12-30}}

The use of calamine lotion dates back as far as 1500 BC.{{cite book| vauthors = Darnton-Hill I, Ahmed F, Samman S | chapter = The impact of micronutrients on inflammation and health in low-and middle-income countries. | veditors = Bendich A, Deckelbaum RJ |title= Preventive Nutrition: The Comprehensive Guide for Health Professionals|date= 2016|publisher= Springer|isbn= 9783319224312|pages = 597-644 (608) |edition= 5th |chapter-url= https://books.google.com/books?id=l7xPCwAAQBAJ&pg=PA608|language= en|url-status= live|archive-url= https://web.archive.org/web/20161230000055/https://books.google.ca/books?id=l7xPCwAAQBAJ&pg=PA608|archive-date= 2016-12-30}} It is on the World Health Organization's List of Essential Medicines.{{cite book | vauthors = ((World Health Organization)) | title = World Health Organization model list of essential medicines: 21st list 2019 | year = 2019 | hdl = 10665/325771 | author-link = World Health Organization | publisher = World Health Organization | location = Geneva | id = WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO | hdl-access=free }} Calamine is available over-the-counter as a generic medication.{{cite book | vauthors = Hamilton R | title = Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition | date = 2015 | publisher = Jones & Bartlett Learning | isbn = 9781284057560 | page = 191 }}