carboxylate transporter
{{Short description|Membrane transport protein}}
A carboxylate transporter is a membrane transport protein that transports carboxylate.
They are responsible for the reabsorption of filtered carboxylate in renal physiology, resulting in a 100%{{cite book |author=Walter F., PhD. Boron |title=Medical Physiology: A Cellular And Molecular Approaoch |publisher=Elsevier/Saunders |isbn=1-4160-2328-3 }} Page 799 reabsorption in the proximal tubule.
In proximal tubule
In the renal proximal tubule, there are several kinds of carboxylate transporters in the apical membrane and the basolateral membrane.
=Apical=
- Na-monocarboxylate cotransporter
- 3Na-dicarboxylate cotransporter
- 3Na-tricarboxylate cotransporter
=Basolateral=
- H-monocarboxylate cotransporter
- organic anion-dicarboxylate exchanger