cellobiose phosphorylase

{{infobox enzyme

| Name = cellobiose phosphorylase

| EC_number = 2.4.1.20

| CAS_number = 9030-20-0

| GO_code = 0047738

| image = 3s4a.jpg

| width = 270

| caption = Cellobiose phosphorylase dimer, Cellulomonas uda

}}

In enzymology, a cellobiose phosphorylase ({{EC number|2.4.1.20}}) is an enzyme that catalyzes the chemical reaction

:cellobiose + phosphate $\rightleftharpoons$ alpha-D-glucose 1-phosphate + D-glucose

Thus, the two substrates of this enzyme are cellobiose and phosphate, whereas its two products are alpha-D-glucose 1-phosphate and D-glucose.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is cellobiose:phosphate alpha-D-glucosyltransferase. This enzyme participates in starch and sucrose metabolism.

Structural studies

As of late 2006, two structures have been solved for this class of enzymes, with PDB accession codes {{PDB link|2CQS}} and {{PDB link|2CQT}}.

References

{{cite journal | vauthors = Alexander JK | title = Purification and specificity of cellobiose phosphorylase from Clostridium thermocellum | journal = The Journal of Biological Chemistry | volume = 243 | issue = 11 | pages = 2899–904 | date = June 1968 | doi = 10.1016/S0021-9258(18)93356-9 | doi-access = free | pmid = 5653182 }}
{{cite journal | vauthors = Ayers WA | title = Phosphorolysis and synthesis of cellobiose by cell extracts from Ruminococcus flavefaciens | journal = The Journal of Biological Chemistry | volume = 234 | pages = 2819–22 | date = November 1959 | issue = 11 | doi = 10.1016/S0021-9258(18)69677-2 | doi-access = free | pmid = 13795349 }}

Category:EC 2.4.1

Category:Enzymes of known structure