compound 48/80

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| ImageFile = Compound 48-80.svg

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| IUPACName = Poly({2-methoxy-5-[2-(methylamino)ethyl]-1,3-phenylene}methylene)

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| UNNumber = 2811

| RTECS = Gk2402500

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| Section2 = {{Chembox Properties

| Formula = (C₁₁H₁₅NO)_n

| MolarMass = Variable

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| Solubility = 50 mg/mL{{cite web | url = https://www.sigmaaldrich.com/catalog/product/sigma/c2313 | title = Compound48/80 | publisher = Sigma-Aldrich}}

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| Section3 = {{Chembox Hazards

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| HPhrases = {{H-phrases|301|311|331}}

| PPhrases = {{P-phrases|261|280|301|310|330|302|352|312|304|340|403|233}}

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Compound 48/80 is a polymer produced by the condensation of N-methyl-p-methoxyphenethylamine with formaldehyde. It promotes histamine release,{{cite journal | journal = Br J Pharmacol | year = 1970 | volume = 38 | issue = 1 | pages = 253–262 | title = Mechanisms of histamine release by compound 48/80 | author = A. M. Rothschild | pmid = 4189829 | pmc = 1702640 | doi=10.1111/j.1476-5381.1970.tb10354.x}} and in biochemical research, compound 48/80 is used to promote mast cell degranulation.{{cite journal | doi = 10.1371/journal.pone.0052104| pmid = 23272218| title = The Mast Cell Degranulator Compound 48/80 Directly Activates Neurons| journal = PLOS ONE| volume = 7| issue = 12| pages = e52104| year = 2012| last1 = Schemann| first1 = Michael| last2 = Kugler| first2 = Eva Maria| last3 = Buhner| first3 = Sabine| last4 = Eastwood| first4 = Christopher| last5 = Donovan| first5 = Jemma| last6 = Jiang| first6 = Wen| last7 = Grundy| first7 = David| pmc=3525567| bibcode = 2012PLoSO...752104S| doi-access = free}}