concentrative nucleoside transporter

{{Infobox protein family

| Symbol = Nucleos_tra2_C

| Name = Nucleos_tra2_C

| image =

| width =

| caption =

| Pfam = PF07662

| Pfam_clan =

| InterPro = IPR011657

| SMART =

| PROSITE =

| MEROPS =

| SCOP =

| TCDB = 2.A.41

| OPM family = 388

| OPM protein = 3tij

| CAZy =

| CDD =

}}

Human concentrative nucleoside transporters include SLC28A1, SLC28A2 and SLC28A3 proteins. SLC28A2 is a purine-specific Na⁺-nucleoside cotransporter localised to the bile canalicular membrane.{{cite journal | vauthors = Che M, Ortiz DF, Arias IM | title = Primary structure and functional expression of a cDNA encoding the bile canalicular, purine-specific Na(+)-nucleoside cotransporter | journal = The Journal of Biological Chemistry | volume = 270 | issue = 23 | pages = 13596–9 | date = Jun 1995 | pmid = 7775409 | doi = 10.1074/jbc.270.23.13596 | doi-access = free }} SLC28A1 is a Na⁺-dependent nucleoside transporter selective for pyrimidine nucleosides and adenosine. It also transports the anti-viral nucleoside analogues Zidovudine and Zalcitabine.{{cite journal | vauthors = Huang QQ, Yao SY, Ritzel MW, Paterson AR, Cass CE, Young JD | title = Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein | journal = The Journal of Biological Chemistry | volume = 269 | issue = 27 | pages = 17757–60 | date = Jul 1994 | doi = 10.1016/S0021-9258(17)32370-0 | pmid = 8027026 | doi-access = free }}