conjunctival suffusion

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|image = Conjunctival suffusion of the eyes due to leptospirosis.jpg

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|caption = Conjunctival suffusion (red conjunctiva) together with jaundice is a specific feature of leptospirosis

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|diagnosis = Weil's disease, Hantavirus

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Conjunctival suffusion is an eye finding occurring early in leptospirosis, which is caused by Leptospira interrogans. Conjunctival suffusion is characterized by redness of the conjunctiva that resembles conjunctivitis, but it does not involve inflammatory exudates. Swelling of the conjunctiva (chemosis) is seen along the corners of the eye (palpebral fissures).

About 30 percent of people with leptospirosis (also known as Weil's disease) develop conjunctival suffusion.{{cite book|last=Goldman|first=Lee|title=Goldman's Cecil Medicine|publisher=Elsevier Saunders|location=Philadelphia|isbn=978-1437727883|year=2011|pages=1938|edition=24th}} When it does occur, it develops towards the end of the early phase of the illness. Even in severe cases, the suffusion occurs in the first phase of the illness.{{cite web|last=Gompf|first=Sandra|title=Leptospirosis Clinical Presentation|url=http://emedicine.medscape.com/article/220563-clinical#showall|work=WebMD, LLC|publisher=Medscape|accessdate=9 December 2012}}

Conjunctival suffusion may also occur in patients with a Hantavirus infection.{{cite journal|last=Duchin|first=Jeffrey S.|author2=Koster, Frederick T. |author3=Peters, C.J. |author4=Simpson, Gary L. |author5=Tempest, Bruce |author6=Zaki, Sherif R. |author7=Ksiazek, Thomas G. |author8=Rollin, Pierre E. |author9=Nichol, Stuart |author10=Umland, Edith T. |author11=Moolenaar, Ronald L. |author12=Reef, Susan E. |author13=Nolte, Kurt B. |author14=Gallaher, Margaret M. |author15=Butler, Jay C. |author16=Breiman, Robert F. |title=Hantavirus Pulmonary Syndrome: A Clinical Description of 17 Patients with a Newly Recognized Disease|journal=New England Journal of Medicine|date=Apr 7, 1994|volume=330|issue=14|pages=949–955|doi=10.1056/NEJM199404073301401|pmid=8121458|doi-access=free }} In a 1994 study of 17 patients with Hantavirus infections, 3 had conjunctival suffusion.