copper gluconate

{{Short description|Chemical compound}}

{{Drugbox

| Verifiedfields = changed

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| verifiedrevid = 447430210

| IUPAC_name = Copper(II) gluconate

| image = copper gluconate.png

| tradename =

| Drugs.com = {{drugs.com|CONS|copper_gluconate}}

| MedlinePlus = a601072

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| routes_of_administration = Oral

| bioavailability =

| protein_bound =

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| CAS_number_Ref = {{cascite|correct|??}}

| CAS_number = 527-09-3

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = RV823G6G67

| ATC_prefix = V03

| ATC_suffix = AB20

| DrugBank_Ref = {{drugbankcite|correct|drugbank}}

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| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}

| ChemSpiderID = 10242

| chemical_formula =

| C=12 | H=22 | Cu=1 | O=14

| PubChem = 10692

| SMILES = C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.[Cu+2]

| StdInChI_Ref = {{stdinchicite|changed|chemspider}}

| StdInChI = 1S/2C6H12O7.Cu/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1

| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}

| StdInChIKey = OCUCCJIRFHNWBP-IYEMJOQQSA-L

| melting_point = 156

| solubility = 30

}}

Copper gluconate is the copper salt of D-gluconic acid. It is an odorless light blue or blue-green crystal or powder which is easily soluble in water and insoluble in ethanol.{{cite web |url=http://www.lyty369.com/Product-38.html |title=产品列表-葡萄糖酸铜 |trans-title=Product list - copper gluconate |publisher=Liaoyang Tengyuan Food Additives Factory |accessdate=March 29, 2013 |archive-url=https://web.archive.org/web/20150402134321/http://www.lyty369.com/Product-38.html |archive-date=April 2, 2015 |url-status=dead }} {{in lang|zh}}{{cite web |url=http://www.chemicalland21.com/lifescience/foco/COPPER%20GLUCONATE.htm |title=Copper Gluconate |publisher=ChemicalLand21 |accessdate=March 29, 2013}}

Uses

  • Dietary supplement to treat copper deficiency.
  • Ingredient of Retsyn, which was an ingredient of Certs breath mints.
  • Fertilizer deficiency corrector to treat lacks of this nutrient.{{cite journal | vauthors = Sawyer DT |title=Metal-Gluconate Complexes |journal= Chemical Reviews |date=1964 |volume=64 |issue=6 |pages=633–643 |doi=10.1021/cr60232a003}}

Side effects

The U.S. Institute of Medicine (IOM) sets tolerable upper intake levels (ULs) for vitamins and minerals when evidence is sufficient. In the case of copper the adult UL is set at 10 mg/day.{{cite book | chapter = Chapter 9: Copper | chapter-url = https://www.nap.edu/read/10026/chapter/9 | pages = 224–257 |title=DRI: dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc : a report of the Panel on Micronutrients ... and the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes | author = Food and Nutrition Board, Institute of Medicine |date=2001 |publisher=National Academy Press |location=Washington, D.C. |isbn=978-0-309-07290-8}}

Copper gluconate is sold as a dietary supplement to provide copper. The typical dose is 2.0 mg copper per day. This is one-fifth what the IOM considers a safe upper limit. Long-term intake at amounts higher than the UL may cause liver damage.

References

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