dense irregular connective tissue
{{Short description|Type of connective tissue in animals}}
File:Blausen 0296 DenseIrregularCT.png
Dense irregular connective tissue has fibers that are not arranged in parallel bundles as in dense regular connective tissue.
Dense irregular connective tissue has less ground substance than loose connective tissue.{{cite book|title=Junqueira's basic histology : text & atlas|date=2013|publisher=McGraw-Hill Medical|isbn=978-0-07-180798-2|edition=13th [rev.]|location=New York [etc.]|last1=Mescher|first1=Anthony L.}} Fibroblasts are the predominant cell type, scattered sparsely across the tissue.{{cite web|url=http://www.courseweb.uottawa.ca/medicine-histology/English/SS_BasicTissues/Connective_Tissue.htm|title=Connective Tissue|accessdate=2008-11-27|url-status=dead|archiveurl=https://web.archive.org/web/20081107231710/http://www.courseweb.uottawa.ca/medicine-histology/English/SS_BasicTissues/Connective_Tissue.htm|archivedate=2008-11-07}}
Function
This type of connective tissue is found mostly in the reticular layer (or deep layer) of the dermis.{{Cite web |url=http://www.pc.ctc.edu/hart/ctprop/dirr.html |title=Dense irregular connective tissue |access-date=2009-10-17 |archive-date=2009-09-25 |archive-url=https://web.archive.org/web/20090925090912/http://www.pc.ctc.edu/hart/ctprop/dirr.html |url-status=dead }} It is also in the sclera and in the deeper skin layers. Due to high portions of collagenous fibers, dense irregular connective tissue provides strength, making the skin resistant to tearing by stretching forces from different directions.{{Cite book|title=Histology: A Text and Atlas: With Correlated Cell and Molecular Biology 7th Edition|last=Pawlina|first=Wojciech|publisher=J. B. Lippincott|year=2016|isbn=978-1451187427|location=China|pages=158–159}}
Dense irregular connective tissue also makes up submucosa of the digestive tract, lymph nodes, and some types of fascia.{{Cite web |url=http://bioweb.uwlax.edu/APLab/Table_of_Contents/Lab_02/Irregular_2/irregular_2.html |title=Dense irregular connective tissue 2 |access-date=2009-10-17 |archive-url=https://web.archive.org/web/20090923160223/http://bioweb.uwlax.edu/APlab/Table_of_Contents/Lab_02/Irregular_2/irregular_2.html |archive-date=2009-09-23 |url-status=dead }} Other examples include periosteum and perichondrium of bones, and the tunica albuginea of testis. In the submucosa layer, the fiber bundles course in varying planes allowing the organ to resist excessive stretching and distension.