dithiobutylamine

{{One source|date=July 2023}}

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| Reference = {{cite journal | last1=Lukesh | first1=John C. | last2=Palte | first2=Michael J. | last3=Raines | first3=Ronald T. | title=A Potent, Versatile Disulfide-Reducing Agent from Aspartic Acid | journal=Journal of the American Chemical Society | publisher=American Chemical Society (ACS) | volume=134 | issue=9 | date=2012-02-21 | issn=0002-7863 | doi=10.1021/ja211931f | pages=4057–4059| pmid=22353145 | pmc=3353773 }}

| ImageFile = Dithiobutylamine structure.svg

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| ImageAlt = Skeletal formula of dithiobutylamine

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| ImageAlt1 = Ball-and-stick model of the dithiobutylamine molecule

| PIN = (S)-2-aminobutane-1,4-dithiol

| OtherNames = DTBA

|Section1={{Chembox Identifiers

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| ChemSpiderID = 32696684

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| StdInChI = 1S/C4H11NS2/c5-4(3-7)1-2-6/h4,6-7H,1-3,5H2/t4-/m0/s1

| StdInChIKey = VGLCUHJZKWYDPC-BYPYZUCNSA-N

| CASNo_Ref = (2S)

| CASNo = 1363594-47-1

| CASNo1 = 1363376-98-0

| CASNo1_Comment = (hydrochloride)

| PubChem = 89734616

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| SMILES = SC[C@H](CCS)N

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|Section2={{Chembox Properties

| C=4 | H=11 | N=1 | S=2

| MolarMass = 137.26 g/mol

| Appearance = White solid

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| Odor = Nearly odorless

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| Solubility = Soluble

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|Section3={{Chembox Hazards

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Dithiobutylamine (DTBA) is a reducing agent intended as an alternative for DTT in biochemical uses. It was designed to be easily synthesized in non-racemic form, to have a lower pKa (allowing more effective reduction at neutral pH), and to have a low disulfide E°′ reduction potential. It was rationally designed & reported in 2012. It is commercially available.