enefexine

{{Short description|Abandoned antidepressant}}

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| class = Antidepressant

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| CAS_number = 67765-04-2

| CAS_supplemental =
67765-33-7 (hydrochloride)

| PubChem = 208916

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| ChemSpiderID = 181012

| UNII = 2JMM46GA2V

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| ChEMBL = 2106188

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| synonyms = 4-(4-Ethylphenyl)piperidine

| IUPAC_name = 4-(4-ethylphenyl)piperidine

| C=13 | H=19 | N=1

| SMILES = CCC1=CC=C(C=C1)C2CCNCC2

| StdInChI = 1S/C13H19N/c1-2-11-3-5-12(6-4-11)13-7-9-14-10-8-13/h3-6,13-14H,2,7-10H2,1H3

| StdInChIKey = NDPOGPAZKKPOPV-UHFFFAOYSA-N

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Enefexine ({{Abbrlink|INN|International Nonproprietary Name}}), also known as 4-(4-ethylphenyl)piperidine, is a drug of the phenylpiperidine group which is described as an antidepressant but was never marketed.{{cite book | vauthors = Elks J | title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies | publisher=Springer US | year=2014 | isbn=978-1-4757-2085-3 | url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA519 | access-date=20 October 2024 | page=519}}{{cite book | title = Use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances | date = 2024 | url = https://iris.who.int/bitstream/handle/10665/379226/9789240099388-eng.pdf | publisher = World Health Organization | page = 100 | isbn = 978-92-4-009938-8 }} It was first described in the literature by 1983.{{cite patent | country = CH | number = 634298 | title=Process for preparing phenylazacycloalkanes | pubdate = 31 January 1983 | url=https://patents.google.com/patent/CH634298A5 | inventor = Georges H, Alberto R, Giorgio FP, Oswald S | assign = Ciba Geigy AG }} The drug was developed by Ciba-Geigy.