enterodiol

{{short description|Lignan formed by the action of intestinal bacteria on lignan precursors found in plants.[1]}}

{{Chembox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 443726976

| ImageFile = Enterodiol.png

| ImageSize = 180px

| PIN = (2R,3R)-2,3-Bis[(3-hydroxyphenyl)methyl]butane-1,4-diol

| OtherNames = (−)-Enterodiol

|Section1={{Chembox Identifiers

| CASNo_Ref = {{cascite|correct|??}}

| CASNo = 80226-00-2

| PubChem = 115089

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = BZF4X2AWRP

| KEGG_Ref = {{keggcite|correct|kegg}}

| KEGG = C18166

| SMILES = C1=CC(=CC(=C1)O)C[C@@H](CO)[C@@H](CC2=CC(=CC=C2)O)CO

| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}

| ChemSpiderID = 102992

| ChEMBL_Ref = {{ebicite|changed|EBI}}

| ChEMBL = 471076

| InChI = 1/C18H22O4/c19-11-15(7-13-3-1-5-17(21)9-13)16(12-20)8-14-4-2-6-18(22)10-14/h1-6,9-10,15-16,19-22H,7-8,11-12H2/t15-,16-/m0/s1

| InChIKey = DWONJCNDULPHLV-HOTGVXAUBO

| StdInChI_Ref = {{stdinchicite|changed|chemspider}}

| StdInChI = 1S/C18H22O4/c19-11-15(7-13-3-1-5-17(21)9-13)16(12-20)8-14-4-2-6-18(22)10-14/h1-6,9-10,15-16,19-22H,7-8,11-12H2/t15-,16-/m0/s1

| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}

| StdInChIKey = DWONJCNDULPHLV-HOTGVXAUSA-N

}}

|Section2={{Chembox Properties

| C=18|H=22|O=4

| Appearance = colorless

| Density =

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|Section3={{Chembox Hazards

| MainHazards =

| FlashPt =

| AutoignitionPt =

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Enterodiol is an organic compound with the formula [HOC6H4CH2CH(CH2OH)]2.

It is formed by the action of intestinal bacteria on lignan precursors. As such it is sometimes classified as a enterolignan or mammalian lignan.{{cite journal |doi=10.1080/10408360701612942|title=Lignans and Human Health|year=2007|last1=Adlercreutz|first1=Herman|journal=Critical Reviews in Clinical Laboratory Sciences|volume=44|issue=5–6|pages=483–525|pmid=17943494|s2cid=31753060}}{{cite journal | author = Lampe JW | title = Isoflavonoid and lignan phytoestrogens as dietary biomarkers | journal = J Nutr | year = 2003 | volume = 133 | issue = Suppl 3 | pages = 956S–964S | pmid = 12612182 | doi=10.1093/jn/133.3.956S| doi-access = free }} Elevated levels of enterodiol in urine are attributed consumption of tea and other lignan-rich foods.{{cite journal |doi=10.1093/ajcn/54.6.1093|title=Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese Diet|year=1991|last1=Adlercreutz|first1=H.|last2= Honjo|first2=H.|last3=Higashi|first3=A.|last4=Fotsis|first4=T.|last5= Hämäläinen|first5=E.|last6=Hasegawa|first6=T.|last7=Okada|first7=H.|journal=The American Journal of Clinical Nutrition|volume=54|issue=6|pages=1093–1100|pmid=1659780|doi-access=free}}

References