estradiol diundecylate
{{Short description|Chemical compound}}
{{Distinguish|Estradiol diundecylenate}}
{{Drugbox
| Verifiedfields =
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| IUPAC_name = [(8R,9S,13S,14S,17S)-13-methyl-3-undecanoyloxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] undecanoate
| image = Estradiol diundecylate.svg
| width = 250px
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| routes_of_administration = Intramuscular injection
| class = Estrogen; Estrogen ester
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| CAS_number_Ref =
| CAS_number = 1263-57-6
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| PubChem = 66422
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| ChemSpiderID_Ref =
| ChemSpiderID = 59796
| synonyms = Estradiol diundecanoate
| C=40 | H=64 | N= | O=4
| SMILES = CCCCCCCCCCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCc4cc(OC(=O)CCCCCCCCCC)ccc4[C@H]3CC[C@]12C
| StdInChI_Ref =
| StdInChI = 1S/C40H64O4/c1-4-6-8-10-12-14-16-18-20-38(41)43-32-23-25-33-31(30-32)22-24-35-34(33)28-29-40(3)36(35)26-27-37(40)44-39(42)21-19-17-15-13-11-9-7-5-2/h23,25,30,34-37H,4-22,24,26-29H2,1-3H3/t34-,35-,36+,37+,40+/m1/s1
| StdInChIKey_Ref =
| StdInChIKey = PWQIMJUJIMPDSQ-OBRFQGJBSA-N
}}
Estradiol diundecylate (brand name Estrolent), or estradiol diundecanoate, also known as 17β-estradiol 3,17β-diundecylate, is an estrogen and an estrogen ester – specifically, the 3,17β-diundecylate ester of estradiol – which has been marketed in Romania.{{cite book | vauthors = Elks J |title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=RA1-PA129|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|page=898}}{{cite book|title=Index Nominum 2000: International Drug Directory|url=https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA406|date=January 2000|publisher=Taylor & Francis|isbn=978-3-88763-075-1|pages=406–}}{{cite book| veditors = Muller NF, Dessing RP |title=European Drug Index: European Drug Registrations, Fourth Edition|url=https://books.google.com/books?id=2HBPHmclMWIC&pg=PA456|date=19 June 1998|publisher=CRC Press|isbn=978-3-7692-2114-5|pages=456–}} It was described, along with a variety of other estradiol esters such as estradiol undecylate, by Karl Junkmann of Schering AG in 1953.{{cite journal| vauthors = Junkmann K | title= Über protrahiert wirksame Östrogene|trans-title=Over protracted effective estrogens|journal=Naunyn-Schmiedebergs Archiv für Experimentelle Pathologie und Pharmakologie|volume=220|issue=5|year=1953|issn=0028-1298|doi=10.1007/BF00246561|s2cid=20753905}}
See also
References
{{Reflist}}
{{Estradiol}}
{{Estrogens and antiestrogens}}
{{Estrogen receptor modulators}}
{{Genito-urinary-drug-stub}}
{{Steroid-stub}}