fetal distress

{{Short description|Paediatric and children's diseases}}

Fetal distress, also known as non-reassuring fetal status, is a condition during pregnancy or labor in which the fetus shows signs of inadequate oxygenation.{{Cite web|date=2014-08-28|title=Fetal Distress|url=https://americanpregnancy.org/healthy-pregnancy/labor-and-birth/fetal-distress/|access-date=2021-09-09|website=American Pregnancy Association|language=en-US}} Due to its imprecision, the term "fetal distress" has fallen out of use in American obstetrics.{{Cite journal|last=Committee on Obstetric Practice, American College of Obstetricians and Gynecologists|date=Dec 2005|title=ACOG Committee Opinion. Number 326, December 2005. Inappropriate use of the terms fetal distress and birth asphyxia|journal=Obstetrics and Gynecology|volume=106|issue=6|pages=1469–1470|doi=10.1097/00006250-200512000-00056|issn=0029-7844|pmid=16319282|doi-access=free}}{{cite journal | vauthors = Parer JT, Livingston EG | title = What is fetal distress? | journal = Am J Obstet Gynecol | volume = 162 | issue = 6 | pages = 1421–5; discussion 1425–7 | date = June 1990 | pmid = 2193513 | doi = 10.1016/0002-9378(90)90901-i }} The term "non-reassuring fetal status" has largely replaced it.{{cite journal | vauthors = Gravett C, Eckert LO, Gravett MG, Dudley DJ, Stringer EM, Mujobu TB, Lyabis O, Kochhar S, Swamy GK | title = Non-reassuring fetal status: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data | journal = Vaccine | volume = 34 | issue = 49 | pages = 6084–6092 | date = December 2016 | pmid = 27461459 | pmc = 5139811 | doi = 10.1016/j.vaccine.2016.03.043 }} It is characterized by changes in fetal movement, growth, heart rate, and presence of meconium stained fluid.

Risk factors for fetal distress/non-reassuring fetal status include anemia, restriction of fetal growth, maternal hypertension or cardiovascular disease, low amniotic fluid or meconium in the amniotic fluid, or a post-term pregnancy. The condition is detected most often with electronic fetal heart rate (FHR) monitoring through cardiotocography (CTG), which allows clinicians to measure changes in the fetal cardiac response to declining oxygen.{{cite journal | vauthors = Kwon JY, Park IY | title = Fetal heart rate monitoring: from Doppler to computerized analysis | journal = Obstet Gynecol Sci | volume = 59 | issue = 2 | pages = 79–84 | date = March 2016 | pmid = 27004196 | pmc = 4796090 | doi = 10.5468/ogs.2016.59.2.79 }} Specifically, heart rate decelerations detected on CTG can represent danger to the fetus and to delivery.

Treatment primarily consists of intrauterine resuscitation, the goal of which is to restore oxygenation of the fetus.{{Cite journal|vauthors = Kither H, Monaghan S|date=Jul 2019|title=Intrauterine fetal resuscitation|url=http://dx.doi.org/10.1016/j.mpaic.2019.04.006|journal=Anaesthesia & Intensive Care Medicine|volume=20|issue=7|pages=385–388|doi=10.1016/j.mpaic.2019.04.006|issn=1472-0299|url-access=subscription}} This can involve improving the position, hydration, and oxygenation of the mother, as well as amnioinfusion to restore sufficient amniotic fluid, delaying preterm labor contractions with tocolysis, and correction of fetal acid-base balance. An algorithm is used to treat/resuscitate babies in need of respiratory support post-birth.{{Cite web|title=Respiratory Support in Neonates and Infants - Pediatrics|url=https://www.msdmanuals.com/professional/pediatrics/respiratory-problems-in-neonates/respiratory-support-in-neonates-and-infants?query=respiratory%20support%20in%20neonates|access-date=2021-09-13|website=MSD Manual Professional Edition|language=en}}

Signs and symptoms

Generally it is preferable to describe specific signs in lieu of declaring fetal distress that include:{{citation needed|date=September 2022}}

File:Cardiotocography diagram.jpg

Some of these signs are more reliable predictors of fetal compromise than others. For example, cardiotocography can give high false positive rates, even when interpreted by highly experienced medical personnel. Fetal acid-base status is a more reliable predictor, but is not always available.{{cite journal | vauthors = Omo-Aghoja L | title = Maternal and fetal Acid-base chemistry: a major determinant of perinatal outcome | journal = Ann Med Health Sci Res | volume = 4 | issue = 1 | pages = 8–17 | date = January 2014 | pmid = 24669324 | pmc = 3952302 | doi = 10.4103/2141-9248.126602 | doi-access = free }}

= Complications =

Complications are primarily those associated with insufficient fetal oxygenation, most notably increased mortality risk. Other complications include fetal encephalopathy, seizures, cerebral palsy, and neurodevelopmental delay.

Causes

Several conditions and risk factors can lead to fetal distress or non-reassuring fetal status, including:

  • Low amniotic fluid (oligohydramnios)
  • If there is too little amniotic fluid around the baby in the uterus, the baby can have trouble moving around in the uterus and its growth and temperature can be impacted. Low amniotic fluid can be caused by placental issues, high gestational blood pressure, some medications, as well as problems with the fetal kidney or urinary tract.{{Cite web|title=Low Amniotic Fluid {{!}} Michigan Medicine|url=https://www.uofmhealth.org/health-library/abr8557|access-date=2021-09-13|website=www.uofmhealth.org}}
  • Meconium in the amniotic fluid
  • If a fetus has meconium in their lungs when they are born, this prevents the pressure in their lungs from falling, which normally facilitates the transition to independent breathing. Since aspiration of meconium can lead to improper oxygenation due to obstruction and carries the potential risk for inflammatory pneumonitis, this is an important diagnosis to make in the setting of newborn respiratory distress.{{Cite web|title=Meconium Aspiration Syndrome - Pediatrics|url=https://www.msdmanuals.com/professional/pediatrics/respiratory-problems-in-neonates/meconium-aspiration-syndrome?query=fetal%20distress|access-date=2021-09-10|website=MSD Manual Professional Edition|language=en}}
  • Gestational Hypertension
  • If hypertension in the mother occurs after the 20th week and meets certain criteria, this is considered preeclampsia/eclampsia. The mechanism of preeclampsia/eclampsia is unknown, but consequences if left untreated can include fetal growth restriction or death, as well as pose medical risks to the mother. Signs and symptoms of preeclampsia can include swelling, protein in the urine, headaches, vomiting, and abnormal labs that assess kidney and liver function, some of which may be considered severe preeclampsia or eclampsia.{{Cite web|title=Preeclampsia and Eclampsia - Gynecology and Obstetrics|url=https://www.msdmanuals.com/professional/gynecology-and-obstetrics/abnormalities-of-pregnancy/preeclampsia-and-eclampsia?query=preeclampsia|access-date=2021-09-13|website=MSD Manual Professional Edition|language=en}}
  • Post-term pregnancy
  • Breathing problems
  • Anemia
  • Abnormal position and presentation of the fetus
  • Multiple births
  • Shoulder dystocia
  • Umbilical cord prolapse
  • Nuchal cord
  • Placental abruption
  • Premature closure of the fetal ductus arteriosus
  • Uterine rupture
  • Intrahepatic cholestasis of pregnancy, a liver disorder during pregnancy
  • Maternal diabetes (Type 1 or 2) or gestational diabetes (GDM){{cite journal | vauthors = Tarvonen M, Hovi P, Sainio S, Vuorela P, Andersson S, Teramo K | title = Intrapartal cardiotocographic patterns and hypoxia-related perinatal outcomes in pregnancies complicated by gestational diabetes mellitus | journal = Acta Diabetol | volume = 58 | issue = 11 | pages = 1563–1573 | date = November 2021 | pmid = 34151398 | pmc = 8505288 | doi = 10.1007/s00592-021-01756-0 |s2cid = 235487220|doi-access = free}}

Prevention

Monitoring of the mother and fetus prior to birth is critical to avoid complications after birth. This is often done via electronic fetal heart rate (FHR) monitoring, which helps providers monitor the fetus' heart rate to ensure it is receiving enough oxygen, monitor the mother's contractions, and monitor the mother's blood pressure and systemic symptoms for gestational hypertension, preeclampsia, or eclampsia.

Treatment

File:Southern Partnership Station 2016 Medical Team 160906-N-CJ186-0025.jpg

Instead of referring to "fetal distress", current recommendations hold to look for more specific signs and symptoms, assess them, and take the appropriate steps to remedy the situation through the implementation of intrauterine resuscitation.{{cite journal | vauthors = Garite TJ, Simpson KR | title = Intrauterine resuscitation during labor | journal = Clin Obstet Gynecol | volume = 54 | issue = 1 | pages = 28–39 | date = March 2011 | pmid = 21278499 | doi = 10.1097/GRF.0b013e31820a062b }} Traditionally the diagnosis of "fetal distress" led the obstetrician to recommend rapid delivery by instrumental delivery or by caesarean section if vaginal delivery is not advised.{{citation needed|date=September 2022}}

An algorithm is used to treat/resuscitate babies in need of respiratory support post-birth. The algorithm steps include: clearing the airways and warming, stimulating, and drying the baby, positive-pressure ventilation (PPV), supplementary oxygen, intubation, chest compressions, and pharmacological therapy. The order of these interventions is set, and each step is done for 30 seconds with heart rate monitoring and assessment of chest movement prior to escalating to the next step in the algorithm.{{Cite web|title=Respiratory Support in Neonates and Infants - Pediatrics|url=https://www.msdmanuals.com/professional/pediatrics/respiratory-problems-in-neonates/respiratory-support-in-neonates-and-infants?query=fetal%20distress|access-date=2021-09-10|website=MSD Manual Professional Edition|language=en}}

References

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