fetal thrombotic vasculopathy

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| image = Fetal thrombotic vasculopathy - intermed mag.jpg

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| caption = Intermediate magnification micrograph of the placental disc showing a thrombosed fetal vein, as may be seen in fetal thrombotic vasculopathy. H&E stain.

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| field = Pathology

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Fetal thrombotic vasculopathy is a chronic disorder characterized by thrombosis in the fetus leading to vascular obliteration and hypoperfusion.

It is associated with cerebral palsy and stillbirth.{{Cite journal | last1 = Kraus | first1 = FT. | last2 = Acheen | first2 = VI. | title = Fetal thrombotic vasculopathy in the placenta: cerebral thrombi and infarcts, coagulopathies, and cerebral palsy. | journal = Hum Pathol | volume = 30 | issue = 7 | pages = 759–69 |date=Jul 1999 | doi = 10.1016/s0046-8177(99)90136-3 | pmid = 10414494 }}

It is more common in women who have diabetes mellitus.

Diagnosis

It can be diagnosed by histomorphologic examination of the placenta and is characterized by fetal vessel thrombosis and clustered fibrotic chorionic villi without blood vessels.

Image: Fetal thrombotic vasculopathy - low mag.jpg | Low mag.

Image: Fetal thrombotic vasculopathy - high mag.jpg | High mag.

Image: Fetal thrombotic vasculopathy - very high mag.jpg | Very high mag.

See also

References