flutrimazole

{{Short description|Chemical compound}}

{{Drugbox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 444165382

| IUPAC_name = (RS)-1-[(2-Fluorophenyl)(4-fluorophenyl)benzyl]-1H-imidazole

| image = Flutrimazole.svg

| width = 180

| chirality = Racemic mixture

| tradename =

| Drugs.com = {{drugs.com|international|flutrimazole}}

| pregnancy_AU =

| pregnancy_US =

| pregnancy_category =

| legal_AU =

| legal_CA =

| legal_UK =

| legal_US =

| legal_status =

| routes_of_administration =

| bioavailability =

| protein_bound =

| metabolism =

| elimination_half-life =

| excretion =

| CAS_number_Ref = {{cascite|correct|??}}

| CAS_number = 119006-77-8

| ATC_prefix = D01

| ATC_suffix = AC16

| ATC_supplemental = {{ATC|G01|AF18}}

| PubChem = 3401

| DrugBank_Ref = {{drugbankcite|correct|drugbank}}

| DrugBank =

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 3284

| ChEMBL_Ref = {{ebicite|changed|EBI}}

| ChEMBL = 2107430

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 776S0UP252

| KEGG_Ref = {{keggcite|correct|kegg}}

| KEGG = D07193

| ChEBI_Ref = {{ebicite|changed|EBI}}

| ChEBI = 82864

| C=22 | H=16 | F=2 | N=2

| smiles = Fc1ccc(cc1)C(c2c(F)cccc2)(c3ccccc3)n4ccnc4

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C22H16F2N2/c23-19-12-10-18(11-13-19)22(26-15-14-25-16-26,17-6-2-1-3-7-17)20-8-4-5-9-21(20)24/h1-16H

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = QHMWCHQXCUNUAK-UHFFFAOYSA-N

}}

Flutrimazole is a wide-spectrum antifungal drug. It is used for the topical treatment of superficial mycoses of the skin. Flutrimazole is an imidazole derivative. Its antifungal activity has been demonstrated in in vivo and in vitro studies to be comparable to that of clotrimazole and higher than bifonazole.{{cite journal | vauthors = Alomar A, Videla S, Delgadillo J, Gich I, Izquierdo I, Forn J | title = Flutrimazole 1% dermal cream in the treatment of dermatomycoses: a multicentre, double-blind, randomized, comparative clinical trial with bifonazole 1% cream. Efficacy of flutrimazole 1% dermal cream in dermatomycoses. Catalan Flutrimazole Study Group | journal = Dermatology | volume = 190 | issue = 4 | pages = 295–300 | date = 1995 | pmid = 7655109 | doi = 10.1159/000246720 }}