fundic gland polyp
{{Infobox medical condition (new)
| name = Fundic gland polyp
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| image = Fundic Gland Polyp, Stomach (3295692096).jpg
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| caption = On histopathology, a fundic gland polyp displays cystically dilated glands.{{cite web|url=https://www.pathologyoutlines.com/topic/stomachfundicgland.html|title=Stomach Polyps - Fundic gland polyp|website=PathologyOutlines|author=Naziheh Assarzadegan, M.D., Raul S. Gonzalez, M.D.}} Topic Completed: 1 November 2017. Minor changes: 11 December 2019
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| specialty = Gastroenterology
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| frequency = 0.8 - 1.9% of patients undergoing EGD
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A fundic gland polyp is a type of polyp, found in the fundus of the stomach. Fundic gland polyps are found in 0.8 to 1.9% of patients who undergo esophagogastroduodenoscopy, and are more common in middle-aged women.{{cite journal | last1 = Weston | first1 = BR | last2 = Helper | first2 = DJ | last3 = Rex | first3 = DK | title = Positive predictive value of endoscopic features deemed typical of gastric fundic gland polyps | journal = Journal of Clinical Gastroenterology | volume = 36 | issue = 5 | pages = 399–402 | year = 2003 | pmid = 12702980 | doi = 10.1097/00004836-200305000-00007 | s2cid = 7220827 }}
The risk of malignancy is very low or none, when sporadic.{{cite web|url=https://www.uptodate.com/contents/gastric-polyps|title=Gastric polyps|author=Varocha Mahachai, MDDavid Y Graham, MDRobert D Odze, MD, FRCPC|website=UpToDate}} Literature review current through: Sep 2020. | This topic last updated: Feb 14, 2019.
Fundic gland polyposis is a medical syndrome with multiple fundic gland polyps. The condition has been described both in patients with familial adenomatous polyposis (FAP) and attenuated variants (AFAP), and in patients in whom it occurs sporadically.{{cite journal | last1 = Declich | first1 = P | last2 = Tavani | first2 = E | last3 = Ferrara | first3 = A | last4 = Caruso | first4 = S | last5 = Bellone | first5 = S | title = Sporadic fundic gland polyps: clinico-pathologic features and associated diseases | journal = Polish Journal of Pathology | volume = 56 | issue = 3 | pages = 131–7 | year = 2005 | pmid = 16334981 }}
File:Pie chart of relative incidences{{verify spelling|date=September 2022|reason=incidence is normally used only in the singular form, perhaps incidence or incidence rates was intended}} of gastric polyps.png|thumb|Relative incidences of gastric polyps (with fundic gland polyp at upper right).{{cite journal|last1=García-Alonso|first1=Francisco Javier|last2=Martín-Mateos|first2=Rosa María|last3=González-Martín|first3=Juan Ángel|last4=Foruny|first4=José Ramón|last5=Vázquez-Sequeiros|first5=Enrique|last6=Boixeda de Miquel|first6=Daniel|title=Gastric polyps: analysis of endoscopic and histological features in our center|journal=Revista Española de Enfermedades Digestivas|volume=103|issue=8|year=2011|pages=416–420|issn=1130-0108|doi=10.4321/S1130-01082011000800005|pmid=21867351 |doi-access=free}}
File:Histopathology of fundic gland polyp, high magnification, annotated.jpg|The glands are lined by chief cells and parietal cells, and possibly also mucinous foveolar cells.
File:Histopathology of a fundic gland polyp with dysplasia.jpg|Fundic gland polyp with dysplasia (center), compared to normal mucosa (at right).