gadoversetamide

{{Short description|Chemical compound}}

{{Drugbox

| Verifiedfields = changed

| verifiedrevid = 461116090

| IUPAC_name =

| image = Gadoversetamide.svg

| width =

| image2 = Gadoversetamide3D.png

| tradename =

| Drugs.com = {{drugs.com|CONS|gadoversetamide}}

| pregnancy_AU =

| pregnancy_US = C

| pregnancy_category =

| licence_EU = yes

| legal_AU =

| legal_CA =

| legal_UK =

| legal_US =

| legal_status =

| routes_of_administration = Intravenous

| bioavailability =

| protein_bound = Nil

| metabolism = Nil

| elimination_half-life = 80 to 120 minutes

| excretion = Renal

| CAS_number_Ref = {{cascite|correct|??}}

| CAS_number = 131069-91-5

| ATC_prefix = V08

| ATC_suffix = CA06

| PubChem = 6435809

| DrugBank_Ref = {{drugbankcite|correct|drugbank}}

| DrugBank = DB00538

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 392041

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = RLM74T3Z9D

| KEGG_Ref = {{keggcite|correct|kegg}}

| KEGG = D01646

| ChEMBL_Ref = {{ebicite|changed|EBI}}

| ChEMBL = 1200457

| C=20 | H=34 | Gd=1 | N=5 | O=10

| smiles = [Gd+3].O=C(NCCOC)CN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC(=O)NCCOC)CC([O-])=O

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C20H37N5O10.Gd/c1-34-9-3-21-16(26)11-24(14-19(30)31)7-5-23(13-18(28)29)6-8-25(15-20(32)33)12-17(27)22-4-10-35-2;/h3-15H2,1-2H3,(H,21,26)(H,22,27)(H,28,29)(H,30,31)(H,32,33);/q;+3/p-3

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = HBEAOBRDTOXWRZ-UHFFFAOYSA-K

}}

Gadoversetamide is a gadolinium-based MRI contrast agent, particularly for imaging of the brain, spine and liver.{{cite web|url=https://www.drugs.com/MMX/Gadoversetamide.html |title=Gadoversetamide Drug Information |date=2000-03-20 |access-date=2007-03-23 |publisher=Drugs.com |url-status=dead |archive-url=https://web.archive.org/web/20071010060901/http://www.drugs.com/MMX/Gadoversetamide.html |archive-date=2007-10-10 }}{{cite book | vauthors = Cheng KT | chapter = Gadoversetamide: Gd-DTPA-BMEA | title = Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. | location = Bethesda (MD) | publisher = National Center for Biotechnology Information (US)| date = 10 December 2007 | pmid = 20641436 | url = https://pubmed.ncbi.nlm.nih.gov/20641436/ }} It is marketed under the trade name OptiMARK.

Notes

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{{Contrast media}}

Category:Organogadolinium compounds

Category:MRI contrast agents

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