geissoschizine methyl ether

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| ImageFile = Methyl Geissoschizine.svg

| ImageSize = 200px

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| PIN = Methyl (2Z)-2-[(2S,3E,12bS)-3-ethylidene-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate

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|Section1={{Chembox Identifiers

| CASNo = 60314-89-8

| CASNo_Ref = {{Cascite|changed|CAS}}

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = TNN2THT2NX

| ChemSpiderID = 4947088

| PubChem = 6443046

| SMILES = C/C=C\1/CN2CCC3=C([C@@H]2C[C@@H]1/C(=C/OC)/C(=O)OC)NC4=CC=CC=C34

| StdInChI=1S/C22H26N2O3/c1-4-14-12-24-10-9-16-15-7-5-6-8-19(15)23-21(16)20(24)11-17(14)18(13-26-2)22(25)27-3/h4-8,13,17,20,23H,9-12H2,1-3H3/b14-4-,18-13-/t17-,20-/m0/s1

| StdInChIKey = VAMJZLUOKJRHOW-XEASWFAXSA-N

}}

|Section2={{Chembox Properties

| C=22 | H=26 | N=2 | O=3

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|Section3={{Chembox Hazards

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Geissoschizine methyl ether is an alkaloid contained in the kampo medicine Yokukansan. Geissoschizine methyl ether has an antagonistic effect on 5-HT7 receptors.{{cite journal|pmid=22968712|year=2013|last1=Ueki|first1=T|last2=Nishi|first2=A|last3=Imamura|first3=S|last4=Kanno|first4=H|last5=Mizoguchi|first5=K|last6=Sekiguchi|first6=K|last7=Ikarashi|first7=Y|last8=Kase|first8=Y|title=Effects of geissoschizine methyl ether, an indole alkaloid in Uncaria hook, a constituent of yokukansan, on human recombinant serotonin(7) receptor|volume=33|issue=1|pages=129–35|doi=10.1007/s10571-012-9878-3|journal=Cellular and Molecular Neurobiology|s2cid=16204547|pmc=11497864}}

References