glafenine
{{Short description|Chemical compound}}
{{Drugbox
| drug_name =
| IUPAC_name = 2,3-Dihydroxypropyl 2-[(7-chloro-4-quinolinyl)amino]benzoate
| image = Glafenine.svg
| image_class = skin-invert-image
| width = 180
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| CAS_number = 3820-67-5
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 46HL4I09AH
| ATCvet =
| ATC_prefix = N02
| ATC_suffix = BG03
| PubChem = 3474
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 31653
| ChEMBL = 146095
| DrugBank =
| ChemSpiderID = 3355
| C=19 | H=17 | Cl=1 | N=2 | O=4
| smiles = O=C(OCC(O)CO)c1ccccc1Nc2c3ccc(Cl)cc3ncc2
| StdInChI = 1S/C19H17ClN2O4/c20-12-5-6-14-17(7-8-21-18(14)9-12)22-16-4-2-1-3-15(16)19(25)26-11-13(24)10-23/h1-9,13,23-24H,10-11H2,(H,21,22)
| StdInChIKey = GWOFUCIGLDBNKM-UHFFFAOYSA-N
| melting_point = 169
| melting_high = 170
}}
Glafenine is a nonsteroidal anti-inflammatory drug (NSAID). Use of glafenine is limited due to the risk of anaphylaxis and acute kidney failure.{{Cite journal | doi = 10.1016/0140-6736(92)91670-4 | title = Withdrawal of glafenine | year = 1992 | journal = The Lancet | volume = 339 | issue = 8789 | pages = 357| s2cid = 54255503 }}{{cite journal | vauthors = Kleinknecht D, Landais P, Goldfarb B | title = Analgesic and non-steroidal anti-inflammatory drug-associated acute renal failure: a prospective collaborative study | journal = Clinical Nephrology | volume = 25 | issue = 6 | pages = 275–81 | date = June 1986 | pmid = 2873910 }}
See also
- Floctafenine, a chemically related NSAID
References
{{Reflist}}
{{Analgesics}}
{{Prostanoidergics}}
Category:Nonsteroidal anti-inflammatory drugs
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