gltS RNA motif

{{primary sources|date=November 2021}}

{{DISPLAYTITLE:gltS RNA motif}}

{{Infobox rfam

| Name = gltS

| image = RF02982.svg

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| caption = Consensus secondary structure and sequence conservation of gltS RNA

| Symbol = gltS

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| Rfam = RF02982

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| RNA_type = Cis-reg

| Tax_domain =

| GO =

| SO = {{SO|0005836}}

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| EntrezGene =

| HGNCid =

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| RefSeq =

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The gltS RNA motif is a conserved RNA structure that was discovered by bioinformatics.{{cite journal |vauthors=Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR |title=Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions |journal=Nucleic Acids Res. |volume=45 |issue=18 |pages=10811–10823 |date=October 2017 |pmid=28977401 |pmc=5737381 |doi=10.1093/nar/gkx699 }}

gltS motifs are found in the bacterial lineage Vibrionaceae.

gltS motif RNAs likely function as cis-regulatory elements, in view of their positions upstream of protein-coding genes. These presumably regulated genes encode subunits of glutamate synthase or a related enzyme (the exact specificity of the enzyme is uncertain). A glutamine riboswitch was discovered that is often located upstream of glutamate synthase genes, but is also present upstream of other genes, such as those encoding glutamine synthetase and ammonium transporters.